JP2014515352A - シアリダーゼ阻害剤を用いた血小板の保存の改善法 - Google Patents
シアリダーゼ阻害剤を用いた血小板の保存の改善法 Download PDFInfo
- Publication number
- JP2014515352A JP2014515352A JP2014511561A JP2014511561A JP2014515352A JP 2014515352 A JP2014515352 A JP 2014515352A JP 2014511561 A JP2014511561 A JP 2014511561A JP 2014511561 A JP2014511561 A JP 2014511561A JP 2014515352 A JP2014515352 A JP 2014515352A
- Authority
- JP
- Japan
- Prior art keywords
- platelet
- platelets
- sialidase
- source
- pas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/124—Disinfecting agents, e.g. antimicrobials
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161487077P | 2011-05-17 | 2011-05-17 | |
| US61/487,077 | 2011-05-17 | ||
| US201161503984P | 2011-07-01 | 2011-07-01 | |
| US61/503,984 | 2011-07-01 | ||
| US201261613837P | 2012-03-21 | 2012-03-21 | |
| US201261613876P | 2012-03-21 | 2012-03-21 | |
| US61/613,837 | 2012-03-21 | ||
| US61/613,876 | 2012-03-21 | ||
| US13/474,679 US20120294842A1 (en) | 2011-05-17 | 2012-05-17 | Platelet Additive Solution Having a Sialidase Inhibitor |
| US13/474,679 | 2012-05-17 | ||
| PCT/US2012/038462 WO2012158983A2 (en) | 2011-05-17 | 2012-05-17 | Improved platelet storage using a sialidase inhibitor |
| US13/474,473 US20120321601A1 (en) | 2011-05-17 | 2012-05-17 | Increased In Vivo Circulation Time of Platelets After Storage With A Sialidase Inhibitor |
| US13/474,627 US20120321722A1 (en) | 2011-05-17 | 2012-05-17 | Platelet Storage and Reduced Bacterial Proliferation In Platelet Products Using A Sialidase Inhibitor |
| US13/474,473 | 2012-05-17 | ||
| US13/474,627 | 2012-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2014515352A true JP2014515352A (ja) | 2014-06-30 |
Family
ID=49716421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014511561A Pending JP2014515352A (ja) | 2011-05-17 | 2012-05-17 | シアリダーゼ阻害剤を用いた血小板の保存の改善法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2709446A2 (de) |
| JP (1) | JP2014515352A (de) |
| CN (1) | CN103702556A (de) |
| AU (1) | AU2012255137A1 (de) |
| CA (1) | CA2835434A1 (de) |
| WO (1) | WO2012158983A2 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017065280A1 (ja) * | 2015-10-14 | 2017-04-20 | 株式会社メガカリオン | 精製血小板の製造方法 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
| EP2903430A1 (de) * | 2012-10-05 | 2015-08-12 | Velico Medical, Inc. | Plättchenadditivlösung mit beta-galactosidase-inhibitor |
| CN114558032B (zh) * | 2012-12-21 | 2025-07-29 | 安斯泰来再生医药协会 | 由多能干细胞制备血小板的方法及其组合物 |
| WO2014120886A1 (en) * | 2013-01-30 | 2014-08-07 | Velico Medical, Inc. | Platelet additive solution having a self-assembling hydrogel-forming peptide |
| WO2016057041A1 (en) * | 2014-10-09 | 2016-04-14 | Biovec Transfusion, Llc | Compositions and methods for preserving platelet function |
| WO2016164693A1 (en) | 2015-04-10 | 2016-10-13 | Board Of Regents, The University Of Texas System | Compositions and methods for prolonged cell storage |
| WO2017002045A1 (en) | 2015-06-30 | 2017-01-05 | Stemlab, Sa | A viable cell population, method for production and uses thereof |
| CN111235132A (zh) * | 2019-12-23 | 2020-06-05 | 浙江工业大学 | 一种β-半乳糖苷酶、基因、工程菌及其应用 |
| CN117717059A (zh) * | 2022-09-09 | 2024-03-19 | 河络新图生物科技(上海)有限公司 | 一种血小板保存液及其制备方法和用途 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4412835A (en) | 1982-07-06 | 1983-11-01 | E. I. Du Pont De Nemours & Company | Sterile docking process, apparatus and system |
| US5256559A (en) | 1988-03-04 | 1993-10-26 | Biogen, Inc. | Methods and compositions for inhibiting platelet aggregation |
| SE8801537D0 (sv) | 1988-04-26 | 1988-04-26 | Ellco Food Ab | Cellodlingsmedium samt forfarande for dess framstellning |
| US5135916A (en) | 1989-06-12 | 1992-08-04 | Oklahoma Medical Research Foundation | Inhibition of complement mediated inflammatory response |
| US5152905A (en) | 1989-09-12 | 1992-10-06 | Pall Corporation | Method for processing blood for human transfusion |
| US5236716A (en) | 1990-02-12 | 1993-08-17 | Miles Inc. | Platelets concentrate with low white blood cells content |
| US5569579A (en) | 1991-04-01 | 1996-10-29 | Thomas Jefferson University | Synthetic-based platelet storage media |
| US5376524A (en) | 1991-04-01 | 1994-12-27 | Thomas Jefferson University | Platelet storage medium containing acetate and phosphate |
| US5269946A (en) | 1991-05-22 | 1993-12-14 | Baxter Healthcare Corporation | Systems and methods for removing undesired matter from blood cells |
| US5234808A (en) | 1991-10-30 | 1993-08-10 | Thomas Jefferson University | Acetate addition to platelets stored in plasma |
| US5344752A (en) | 1991-10-30 | 1994-09-06 | Thomas Jefferson University | Plasma-based platelet concentrate preparations |
| US5474891A (en) | 1991-10-30 | 1995-12-12 | Thomas Jefferson University | Plasma-based platelet concentrate preparations with additive |
| WO1996014740A1 (en) | 1992-03-02 | 1996-05-23 | Cerus Corporation | Synthetic media for blood components |
| US5459030A (en) * | 1992-03-02 | 1995-10-17 | Steritech, Inc. | Synthetic media compositions for inactivating bacteria and viruses in blood preparations with 8-methoxypsoralen |
| US5529821A (en) | 1992-06-29 | 1996-06-25 | Terumo Kabushiki Kaisha | Container for storing blood or blood component |
| US5571686A (en) | 1994-04-14 | 1996-11-05 | Massachusetts Institute Of Technology | Method of using megapoietin for prolonging the survival & viability of platlets |
| US5582821A (en) | 1994-07-22 | 1996-12-10 | Genetics Institute, Inc. | Methods for treating bleeding disorders |
| US6221669B1 (en) | 1994-10-19 | 2001-04-24 | Lifecell Corporation | Prolonged preservation of blood platelets |
| US5919614A (en) | 1994-10-19 | 1999-07-06 | Lifecell Corporation | Composition comprising three platelet lesion inhibitors for platelet storage |
| US5622867A (en) | 1994-10-19 | 1997-04-22 | Lifecell Corporation | Prolonged preservation of blood platelets |
| DE69532236D1 (de) | 1994-12-16 | 2004-01-15 | Baxter Int | Antikoagulierende Zusammensetzungen für Blutplättchen |
| JP2930908B2 (ja) | 1995-07-19 | 1999-08-09 | 川澄化学工業株式会社 | 血小板保存液 |
| TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
| JP2001524467A (ja) | 1997-11-26 | 2001-12-04 | 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド | ヘテロアリールアミノグアニジンおよびアルコキシグアニジンおよびプロテアーゼインヒビターとしてのこれらの使用 |
| EP1049495A2 (de) | 1998-01-23 | 2000-11-08 | Pall Corporation | System zum verarbeiten von biologischen flüssigkeiten |
| US6344486B1 (en) | 1998-04-03 | 2002-02-05 | 3-Dimensional Pharmaceuticals, Inc. | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors |
| US6417161B1 (en) | 1998-04-24 | 2002-07-09 | 3-Dimensional Pharmaceuticals, Inc. | Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines as protease inhibitors |
| PL344749A1 (en) | 1998-06-11 | 2001-11-19 | Dimensional Pharmaceuticals 3 | Pyrazinone protease inhibitors |
| EP1189901A1 (de) | 1999-05-27 | 2002-03-27 | 3-Dimensional Pharmaceuticals, Inc. | Oxazaheterocyclen als proteasehemmer |
| US6420397B1 (en) | 1999-07-09 | 2002-07-16 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl protease inhibitors and diagnostic imaging agents |
| PL208386B1 (pl) | 2000-07-06 | 2011-04-29 | Daiichi Sankyo Company | Sole addycyjne 2-acetoksy-5-(α-cyklopropylokarbonylo-2-flurobenzylo)-4,5,6,7-tetrahydrotieno[3,2-c]pirydyny z kwasem, lekarstwo zawierające jako składnik czynny te sole, zastosowanie soli, sposoby wytwarzania soli addycyjnych 2-acetoksy-5-(α-cyklopropylokarbonylo-2-fluorobenzylo)-4,5,6,7-tetrahydrotieno[3,2-c]pirydyny z kwasem, sposób wytwarzania chlorowodorku 2-acetoksy-5-(α-cyklopropylokarbonylo-2-fluorobenzylo)-4,5,6,7-tetrahydrotieno[3,2-c]pirydyny |
| JP2004504305A (ja) | 2000-07-17 | 2004-02-12 | 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド | プロテアーゼインヒビターとしての環状オキシグアニジンピラジノン |
| US6635637B2 (en) | 2000-08-04 | 2003-10-21 | Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine protease inhibitors |
| UA75093C2 (en) | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
| EP1331941A1 (de) | 2000-10-13 | 2003-08-06 | Pike Laboratories, Inc. | Kalte aufbewahrungslösung für die konservierung von organen und biologischen geweben |
| US6605302B2 (en) | 2001-07-17 | 2003-08-12 | Osmotica Corp. | Drug delivery device containing oseltamivir and an H1 antagonist |
| WO2004098675A2 (en) | 2003-05-01 | 2004-11-18 | Thermics, Llc | Method and system for warming a fluid |
| WO2006025983A2 (en) | 2004-07-26 | 2006-03-09 | The Regents Of The University Of California | Labeled substrate conjugates for identifying enzyme inhibitors |
| US8052667B2 (en) | 2004-09-07 | 2011-11-08 | Velico Medical, Inc. | Apparatus for prolonging survival of platelets |
| AU2005295467B2 (en) * | 2004-10-15 | 2011-07-07 | Velico Medical, Inc. | Compositions and methods for prolonging survival of platelets |
| US20090175805A1 (en) | 2006-03-13 | 2009-07-09 | The Trustees Of Columbia University In The City Of New York | Neuraminidase Inhibitors and uses thereof |
| WO2008011094A2 (en) | 2006-07-18 | 2008-01-24 | Robert Sackstein | Cytokine induction of selectin ligands on cells |
| CN101181302A (zh) * | 2007-11-29 | 2008-05-21 | 中国人民解放军军事医学科学院野战输血研究所 | 一种保养液以及一种血小板保存液 |
-
2012
- 2012-05-17 AU AU2012255137A patent/AU2012255137A1/en not_active Abandoned
- 2012-05-17 WO PCT/US2012/038462 patent/WO2012158983A2/en not_active Ceased
- 2012-05-17 EP EP12726520.5A patent/EP2709446A2/de not_active Withdrawn
- 2012-05-17 JP JP2014511561A patent/JP2014515352A/ja active Pending
- 2012-05-17 CA CA2835434A patent/CA2835434A1/en not_active Abandoned
- 2012-05-17 CN CN201280023800.4A patent/CN103702556A/zh active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017065280A1 (ja) * | 2015-10-14 | 2017-04-20 | 株式会社メガカリオン | 精製血小板の製造方法 |
| JPWO2017065280A1 (ja) * | 2015-10-14 | 2018-09-13 | 株式会社メガカリオン | 精製血小板の製造方法 |
| US10851343B2 (en) | 2015-10-14 | 2020-12-01 | Megakaryon Corporation | Method for producing purified platelets |
| JP7287634B2 (ja) | 2015-10-14 | 2023-06-06 | 株式会社メガカリオン | 精製血小板の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012255137A1 (en) | 2013-12-12 |
| WO2012158983A3 (en) | 2014-01-03 |
| WO2012158983A2 (en) | 2012-11-22 |
| CA2835434A1 (en) | 2012-11-22 |
| CN103702556A (zh) | 2014-04-02 |
| EP2709446A2 (de) | 2014-03-26 |
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