JP2014519480A5 - - Google Patents
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- Publication number
- JP2014519480A5 JP2014519480A5 JP2014505330A JP2014505330A JP2014519480A5 JP 2014519480 A5 JP2014519480 A5 JP 2014519480A5 JP 2014505330 A JP2014505330 A JP 2014505330A JP 2014505330 A JP2014505330 A JP 2014505330A JP 2014519480 A5 JP2014519480 A5 JP 2014519480A5
- Authority
- JP
- Japan
- Prior art keywords
- il1r1
- cancer
- il1racp
- il1beta
- csc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 101001076418 Homo sapiens Interleukin-1 receptor type 1 Proteins 0.000 claims 2
- 102100026016 Interleukin-1 receptor type 1 Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000000833 heterodimer Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11003183 | 2011-04-15 | ||
| EP11003183.8 | 2011-04-15 | ||
| PCT/US2012/033490 WO2012142391A1 (en) | 2011-04-15 | 2012-04-13 | Anti- il-1r1 inhibitors for use in cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014519480A JP2014519480A (ja) | 2014-08-14 |
| JP2014519480A5 true JP2014519480A5 (2) | 2015-06-11 |
Family
ID=46018101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014505330A Abandoned JP2014519480A (ja) | 2011-04-15 | 2012-04-13 | 癌で使用される抗ｉｌ−１ｒ１阻害物質 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20140308294A1 (2) |
| EP (1) | EP2697260A1 (2) |
| JP (1) | JP2014519480A (2) |
| CN (1) | CN103492416A (2) |
| AU (1) | AU2012242666A1 (2) |
| CA (1) | CA2833147A1 (2) |
| IL (1) | IL228847A0 (2) |
| WO (1) | WO2012142391A1 (2) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011515497A (ja) | 2008-03-26 | 2011-05-19 | セレラント セラピューティクス インコーポレイテッド | 骨髄性血液学的増殖性疾患と関連する免疫グロブリンおよび／またはＴｏｌｌ様受容体タンパク質ならびにその使用 |
| JP7114460B2 (ja) | 2015-06-26 | 2022-08-08 | サノフィ・バイオテクノロジー | モノクローナル抗ＩＬ－１ＲＡｃＰ抗体 |
| CN107033216B (zh) * | 2015-12-08 | 2021-08-03 | 财团法人农业科技研究院 | 靶向癌干细胞的胜肽和其应用 |
| EP3241845A1 (en) | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
| CN110431225B (zh) * | 2017-03-10 | 2024-04-12 | 默克专利股份公司 | 受感染的细胞培养物 |
| EP3401332A1 (en) * | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| CN112512637A (zh) * | 2018-05-29 | 2021-03-16 | 昂科霍斯特公司 | 通过阻断宿主诱导的il-1与放射疗法组合治疗癌症 |
| TW202021618A (zh) | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | 抗ｉｌ１ｒａｐ抗體及其使用方法 |
| CN109468380B (zh) * | 2018-10-31 | 2022-05-17 | 复旦大学附属肿瘤医院 | Il1r2在乳腺癌预后评估与靶向治疗中的应用 |
| WO2020233571A1 (zh) * | 2019-05-20 | 2020-11-26 | 上海一宸医药科技有限公司 | 一种双特异性分子及其制备与用途 |
| AU2023345467A1 (en) | 2022-09-21 | 2025-05-08 | Sanofi Biotechnology | Humanized anti-il-1r3 antibody and methods of use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR8907457A (pt) | 1988-05-27 | 1991-04-02 | Synergen Inc | Inibidores de interleucina-1 |
| US6927044B2 (en) | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
| US6472179B2 (en) | 1998-09-25 | 2002-10-29 | Regeneron Pharmaceuticals, Inc. | Receptor based antagonists and methods of making and using |
| US20030007972A1 (en) * | 1999-02-24 | 2003-01-09 | Edward Tobinick | Cytokine antagonists and other biologics for the treatment of bone metastases |
| WO2001042305A1 (en) | 1999-12-10 | 2001-06-14 | Amgen, Inc. | Interleukin-1 receptor antagonist-like molecules and uses thereof |
| GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
| CA2824167C (en) * | 2002-09-06 | 2018-09-25 | Amgen Inc. | Therapeutic human anti-il-1r1 monoclonal antibody |
| AR045614A1 (es) | 2003-09-10 | 2005-11-02 | Hoffmann La Roche | Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos |
| DK1899378T3 (da) | 2005-06-21 | 2010-02-01 | Xoma Technology Ltd | IL-1 beta-bindende antistoffer og fragmenter deraf |
| US8298533B2 (en) | 2008-11-07 | 2012-10-30 | Medimmune Limited | Antibodies to IL-1R1 |
| WO2010089707A1 (en) * | 2009-02-04 | 2010-08-12 | Yeda Research And Development Co. Ltd. | Methods and kits for determining sensitivity or resistance of prostate cancer to radiation therapy |
| GB2472856B (en) * | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
-
2012
- 2012-04-13 JP JP2014505330A patent/JP2014519480A/ja not_active Abandoned
- 2012-04-13 EP EP12717537.0A patent/EP2697260A1/en not_active Withdrawn
- 2012-04-13 CA CA2833147A patent/CA2833147A1/en not_active Abandoned
- 2012-04-13 WO PCT/US2012/033490 patent/WO2012142391A1/en not_active Ceased
- 2012-04-13 CN CN201280018582.5A patent/CN103492416A/zh active Pending
- 2012-04-13 AU AU2012242666A patent/AU2012242666A1/en not_active Abandoned
- 2012-04-13 US US14/110,173 patent/US20140308294A1/en not_active Abandoned
-
2013
- 2013-10-13 IL IL228847A patent/IL228847A0/en unknown
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