JP2014524902A5 - - Google Patents
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- Publication number
- JP2014524902A5 JP2014524902A5 JP2014515968A JP2014515968A JP2014524902A5 JP 2014524902 A5 JP2014524902 A5 JP 2014524902A5 JP 2014515968 A JP2014515968 A JP 2014515968A JP 2014515968 A JP2014515968 A JP 2014515968A JP 2014524902 A5 JP2014524902 A5 JP 2014524902A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antigen
- binding fragment
- antibody
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161496737P | 2011-06-14 | 2011-06-14 | |
| US201161496986P | 2011-06-14 | 2011-06-14 | |
| US61/496,986 | 2011-06-14 | ||
| US61/496,737 | 2011-06-14 | ||
| PCT/US2012/042315 WO2012174160A1 (en) | 2011-06-14 | 2012-06-13 | Tem8 antibodies, conjugates thereof, and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014524902A JP2014524902A (ja) | 2014-09-25 |
| JP2014524902A5 true JP2014524902A5 (2) | 2015-07-09 |
Family
ID=47357454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014515968A Pending JP2014524902A (ja) | 2011-06-14 | 2012-06-13 | Ｔｅｍ８抗体、そのコンジュゲートおよびそれらの使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9181340B2 (2) |
| EP (1) | EP2721071A4 (2) |
| JP (1) | JP2014524902A (2) |
| CA (1) | CA2837892A1 (2) |
| WO (1) | WO2012174160A1 (2) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2637692A4 (en) * | 2010-11-12 | 2014-09-10 | Scott & White Healthcare | ANTIBODIES TO THE ENDOTHELIAL TUMOR MARKER 8 |
| WO2014164544A1 (en) * | 2013-03-09 | 2014-10-09 | Baylor College Of Medicine | Vascular-targeted t-cell therapy |
| WO2014201202A1 (en) * | 2013-06-14 | 2014-12-18 | Texas Tech University System | Rna interference-based therapeutic against anthrax |
| CN105813654B (zh) | 2013-10-11 | 2019-05-31 | 美国政府(由卫生和人类服务部的部长所代表) | Tem8抗体及其用途 |
| JP6795877B2 (ja) * | 2013-12-25 | 2020-12-02 | 東京応化工業株式会社 | 表面被覆膜の形成方法及び表面被覆膜を有する太陽電池 |
| WO2015191610A2 (en) * | 2014-06-09 | 2015-12-17 | Biomed Valley Discoveries, Inc. | Combination therapies using agents that target tumor-associated stroma or tumor cells and other pathways |
| US11034757B2 (en) | 2014-06-09 | 2021-06-15 | Biomed Valley Discoveries, Inc. | Combination therapies using agents that target tumor-associated stroma or tumor cells and tumor vasculature |
| WO2015191596A1 (en) * | 2014-06-09 | 2015-12-17 | Biomed Valley Discoveries, Inc. | Combination therapies using platinum agents and agents that target tumor-associated stroma or tumor cells |
| WO2015191590A2 (en) * | 2014-06-09 | 2015-12-17 | Biomed Valley Discoveries, Inc. | Combination therapies targeting tumor-associated stroma or tumor cells and microtubules |
| WO2015191615A2 (en) * | 2014-06-09 | 2015-12-17 | Biomed Valley Discoveries, Inc. | Combination therapies using agents that target tumor-associated stroma or tumor cells and alkylating agents |
| US10758613B2 (en) * | 2014-06-09 | 2020-09-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services National Intstitutes Of Health | Combination therapies using anti-metabolites and agents that target tumor-associated stroma or tumor cells |
| US11033621B2 (en) | 2014-06-09 | 2021-06-15 | Biomed Valley Discoveries, Inc. | Combination therapies targeting tumor-associated stroma or tumor cells |
| US10758614B2 (en) * | 2014-06-09 | 2020-09-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services National Institutes Of Health | Combination therapies targeting tumor-associated stroma or tumor cells and topoisomerase |
| WO2017139498A1 (en) * | 2016-02-09 | 2017-08-17 | Cour Pharmaceuticals Development Company Inc. | Timps encapsulating japanese cedar pollen epitopes |
| EP3554544A4 (en) | 2016-12-16 | 2020-07-29 | Bluefin Biomedicine, Inc. | ANTI-PROTEIN 1 ANTIBODY CONTAINING AN ANTI-CUB DOMAIN (CDCP1), ANTIBODY-DRUG CONJUGATES AND THEIR METHODS OF USE |
| CN108707199A (zh) * | 2018-05-29 | 2018-10-26 | 廊坊康宝汇泰生物技术有限公司 | 靶向tem8的嵌合抗原受体t细胞及其应用 |
| WO2024245342A1 (zh) * | 2023-05-31 | 2024-12-05 | 应世生物科技(南京)有限公司 | 一种靶向tem8的抗体或其抗原结合片段及其应用 |
| WO2025179281A1 (en) * | 2024-02-23 | 2025-08-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Treatment of cardiovascular disease with antxr1 antibodies |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2810195B1 (fr) | 2000-06-16 | 2002-08-30 | Kuhn Audureau Sa | Machine de coupe pouvant etre accrochee a un tracteur et comprenant un mecanisme de coupe a rotor et couteaux perfectionne |
| CA2416732C (en) | 2000-08-02 | 2016-02-09 | Brad St. Croix | Endothelial cell expression patterns |
| EP1395657B1 (en) | 2000-12-05 | 2007-04-18 | Wisconsin Alumni Research Foundation | Receptor for bacillus anthracis toxin |
| AU2002258543B2 (en) | 2001-04-11 | 2008-05-22 | The Johns Hopkins University | Endothelial cell expression patterns |
| AU2003281867A1 (en) | 2002-03-28 | 2004-02-23 | University Of Florida | Antisense nucleic acids |
| WO2004078942A2 (en) | 2003-03-04 | 2004-09-16 | Kirin Beer Kabushiki Kaisha | Endothelial cell specific antibodies and uses thereof |
| WO2005038022A1 (ja) * | 2003-10-20 | 2005-04-28 | Teijin Pharma Limited | 骨及び／又は関節疾患関連遺伝子 |
| WO2005081749A2 (en) | 2004-01-23 | 2005-09-09 | Avanir Pharmaceuticals, Inc. | Neutralizing human antibodies to anthraxtoxin |
| ITRM20060337A1 (it) * | 2006-06-27 | 2007-12-28 | Biosoot Srl | Gene tem8 (tumor endotelial marker 8) e sue forme di espressione ed usi diagnostici e terapeutici |
| CN101591395A (zh) * | 2009-07-13 | 2009-12-02 | 杭州屹源生物技术有限公司 | 抗人肿瘤血管内皮标志分子8胞外区的人源性单链抗体及其应用 |
| EP2637692A4 (en) * | 2010-11-12 | 2014-09-10 | Scott & White Healthcare | ANTIBODIES TO THE ENDOTHELIAL TUMOR MARKER 8 |
| WO2012172495A1 (en) | 2011-06-14 | 2012-12-20 | Novartis Ag | Compositions and methods for antibodies targeting tem8 |
-
2012
- 2012-06-13 JP JP2014515968A patent/JP2014524902A/ja active Pending
- 2012-06-13 US US14/126,372 patent/US9181340B2/en active Active
- 2012-06-13 WO PCT/US2012/042315 patent/WO2012174160A1/en not_active Ceased
- 2012-06-13 EP EP12799947.2A patent/EP2721071A4/en not_active Withdrawn
- 2012-06-13 CA CA2837892A patent/CA2837892A1/en not_active Abandoned
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