JP2017193547A - 口腔清浄用発泡性錠剤 - Google Patents

口腔清浄用発泡性錠剤 Download PDF

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Publication number: JP2017193547A
Authority: JP; Japan
Prior art keywords: tablet; foaming; volume; oral cleaning; foaming agent
Prior art date: 2017-05-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP2017092508A

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English (en)

Japanese (ja)

Other versions

JP2017193547A5 (pl

Inventor

邦赫小牧

Kuniaki Komaki

邦赫小牧

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-05-08

Filing date

2017-05-08

Publication date

2017-10-26

2017-05-08 Application filed by Individual filed Critical Individual

2017-05-08 Priority to JP2017092508A priority Critical patent/JP2017193547A/ja

2017-10-26 Publication of JP2017193547A publication Critical patent/JP2017193547A/ja

2018-02-15 Publication of JP2017193547A5 publication Critical patent/JP2017193547A5/ja

Status Pending legal-status Critical Current

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238000004140 cleaning Methods 0.000 title claims abstract description 78
238000005187 foaming Methods 0.000 title claims abstract description 62
239000004088 foaming agent Substances 0.000 claims abstract description 83
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 40
239000000463 material Substances 0.000 claims abstract description 28
229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract description 20
235000017557 sodium bicarbonate Nutrition 0.000 claims abstract description 20
239000000203 mixture Substances 0.000 claims abstract description 11
239000001913 cellulose Substances 0.000 claims abstract description 8
229920002678 cellulose Polymers 0.000 claims abstract description 8
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 3
239000003826 tablet Substances 0.000 claims description 207
239000007938 effervescent tablet Substances 0.000 claims description 32
238000004806 packaging method and process Methods 0.000 claims description 32
230000003746 surface roughness Effects 0.000 claims description 22
239000002245 particle Substances 0.000 claims description 19
239000000758 substrate Substances 0.000 claims description 11
229910012375 magnesium hydride Inorganic materials 0.000 claims description 9
CSDQQAQKBAQLLE-UHFFFAOYSA-N 4-(4-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine Chemical compound C1=CC(Cl)=CC=C1C1C(C=CS2)=C2CCN1 CSDQQAQKBAQLLE-UHFFFAOYSA-N 0.000 claims description 7
229910000838 Al alloy Inorganic materials 0.000 claims description 7
239000011888 foil Substances 0.000 claims description 7
239000002552 dosage form Substances 0.000 claims description 6
230000003287 optical effect Effects 0.000 claims description 6
229920003023 plastic Polymers 0.000 claims description 6
-1 sodium aluminum hydride Chemical compound 0.000 claims description 6
238000005452 bending Methods 0.000 claims description 5
UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 4
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
230000000694 effects Effects 0.000 abstract description 34
239000003795 chemical substances by application Substances 0.000 abstract description 6
238000005498 polishing Methods 0.000 abstract description 6
210000000214 mouth Anatomy 0.000 description 51
239000006260 foam Substances 0.000 description 16
210000002105 tongue Anatomy 0.000 description 15
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 14
210000003296 saliva Anatomy 0.000 description 11
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
239000001257 hydrogen Substances 0.000 description 8
229910052739 hydrogen Inorganic materials 0.000 description 8
RSHAOIXHUHAZPM-UHFFFAOYSA-N magnesium hydride Chemical compound [MgH2] RSHAOIXHUHAZPM-UHFFFAOYSA-N 0.000 description 8
238000000034 method Methods 0.000 description 8
239000001569 carbon dioxide Substances 0.000 description 7
229910002092 carbon dioxide Inorganic materials 0.000 description 7
239000000126 substance Substances 0.000 description 7
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 6
208000028169 periodontal disease Diseases 0.000 description 5
POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 4
208000002925 dental caries Diseases 0.000 description 4
210000003128 head Anatomy 0.000 description 4
230000002265 prevention Effects 0.000 description 4
206010035664 Pneumonia Diseases 0.000 description 3
230000009471 action Effects 0.000 description 3
239000004480 active ingredient Substances 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
238000010586 diagram Methods 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
238000002156 mixing Methods 0.000 description 3
239000003973 paint Substances 0.000 description 3
239000003223 protective agent Substances 0.000 description 3
230000002087 whitening effect Effects 0.000 description 3
POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 2
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
241000894006 Bacteria Species 0.000 description 2
206010006326 Breath odour Diseases 0.000 description 2
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 2
239000003082 abrasive agent Substances 0.000 description 2
229960000458 allantoin Drugs 0.000 description 2
230000003796 beauty Effects 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
239000011248 coating agent Substances 0.000 description 2
238000000576 coating method Methods 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
238000001035 drying Methods 0.000 description 2
239000011737 fluorine Substances 0.000 description 2
229910052731 fluorine Inorganic materials 0.000 description 2
235000003599 food sweetener Nutrition 0.000 description 2
230000036541 health Effects 0.000 description 2
238000005259 measurement Methods 0.000 description 2
210000003254 palate Anatomy 0.000 description 2
230000001737 promoting effect Effects 0.000 description 2
239000011734 sodium Substances 0.000 description 2
230000001954 sterilising effect Effects 0.000 description 2
239000003765 sweetening agent Substances 0.000 description 2
210000000216 zygoma Anatomy 0.000 description 2
NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 description 1
ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 1
229910000013 Ammonium bicarbonate Inorganic materials 0.000 description 1
108010011485 Aspartame Proteins 0.000 description 1
238000012935 Averaging Methods 0.000 description 1
239000004604 Blowing Agent Substances 0.000 description 1
NMWISFJHUUXHOD-HYXAFXHYSA-N C/N=C\CC[O]=P Chemical compound C/N=C\CC[O]=P NMWISFJHUUXHOD-HYXAFXHYSA-N 0.000 description 1
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
244000246386 Mentha pulegium Species 0.000 description 1
235000016257 Mentha pulegium Nutrition 0.000 description 1
235000004357 Mentha x piperita Nutrition 0.000 description 1
229930003268 Vitamin C Natural products 0.000 description 1
TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
230000003213 activating effect Effects 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
230000032683 aging Effects 0.000 description 1
AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 1
235000012538 ammonium bicarbonate Nutrition 0.000 description 1
239000001099 ammonium carbonate Substances 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
239000000605 aspartame Substances 0.000 description 1
235000010357 aspartame Nutrition 0.000 description 1
IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
229960003438 aspartame Drugs 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
230000008901 benefit Effects 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
229960001927 cetylpyridinium chloride Drugs 0.000 description 1
YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
230000008859 change Effects 0.000 description 1
239000003086 colorant Substances 0.000 description 1
238000005336 cracking Methods 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003814 drug Substances 0.000 description 1
RAQDACVRFCEPDA-UHFFFAOYSA-L ferrous carbonate Chemical compound [Fe+2].[O-]C([O-])=O RAQDACVRFCEPDA-UHFFFAOYSA-L 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000013355 food flavoring agent Nutrition 0.000 description 1
239000007789 gas Substances 0.000 description 1
208000007565 gingivitis Diseases 0.000 description 1
235000001050 hortel pimenta Nutrition 0.000 description 1
150000002431 hydrogen Chemical class 0.000 description 1
125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
210000001847 jaw Anatomy 0.000 description 1
210000004072 lung Anatomy 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
238000000465 moulding Methods 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
235000019629 palatability Nutrition 0.000 description 1
230000035515 penetration Effects 0.000 description 1
201000001245 periodontitis Diseases 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
235000015497 potassium bicarbonate Nutrition 0.000 description 1
239000011736 potassium bicarbonate Substances 0.000 description 1
TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
239000002994 raw material Substances 0.000 description 1
230000003252 repetitive effect Effects 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
230000028327 secretion Effects 0.000 description 1
RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
238000003892 spreading Methods 0.000 description 1
230000007480 spreading Effects 0.000 description 1
238000003860 storage Methods 0.000 description 1
230000009747 swallowing Effects 0.000 description 1
229940034610 toothpaste Drugs 0.000 description 1
239000000606 toothpaste Substances 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
235000019154 vitamin C Nutrition 0.000 description 1
239000011718 vitamin C Substances 0.000 description 1
239000000811 xylitol Substances 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
229960002675 xylitol Drugs 0.000 description 1

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JP2017092508A 2017-05-08 2017-05-08 口腔清浄用発泡性錠剤 Pending JP2017193547A (ja)

Priority Applications (1)

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JP2017092508A JP2017193547A (ja)	2017-05-08	2017-05-08	口腔清浄用発泡性錠剤

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JP2017092508A JP2017193547A (ja)	2017-05-08	2017-05-08	口腔清浄用発泡性錠剤

Related Parent Applications (1)

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JP2016085522A Division JP6217052B2 (ja)	2016-04-21	2016-04-21	口腔清浄用発泡性錠剤

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JP2017193547A true JP2017193547A (ja)	2017-10-26
JP2017193547A5 JP2017193547A5 (pl)	2018-02-15

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2024152150A (ja) *	2023-04-14	2024-10-25	井藤漢方製薬株式会社	口腔ケア用錠剤

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JP2002531480A (ja) *	1998-12-05	2002-09-24	スウングカプセルシーオー．，エルティーディー．	口腔清浄用発泡タブレットおよびその製造方法
JP2004026816A (ja) *	2002-05-08	2004-01-29	Sunstar Inc	口腔用組成物
JP2013539768A (ja) *	2010-10-13	2013-10-28	フレゼニウスメディカルケアドイッチェランドゲゼルシャフトミットベシュレンクテルハフツング	簡単な投与のためのリン酸塩結合剤製剤
WO2014042120A1 (ja) *	2012-09-13	2014-03-20	ライオン株式会社	発泡性口腔用組成物、発泡性口腔用固形製剤及び発泡性口腔用製品
JP2015533155A (ja) *	2012-10-11	2015-11-19	アイエックスバイオファーマリミテッド	固体剤形

2017
- 2017-05-08 JP JP2017092508A patent/JP2017193547A/ja active Pending

Patent Citations (5)

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Publication number	Priority date	Publication date	Assignee	Title
JP2002531480A (ja) *	1998-12-05	2002-09-24	スウングカプセルシーオー．，エルティーディー．	口腔清浄用発泡タブレットおよびその製造方法
JP2004026816A (ja) *	2002-05-08	2004-01-29	Sunstar Inc	口腔用組成物
JP2013539768A (ja) *	2010-10-13	2013-10-28	フレゼニウスメディカルケアドイッチェランドゲゼルシャフトミットベシュレンクテルハフツング	簡単な投与のためのリン酸塩結合剤製剤
WO2014042120A1 (ja) *	2012-09-13	2014-03-20	ライオン株式会社	発泡性口腔用組成物、発泡性口腔用固形製剤及び発泡性口腔用製品
JP2015533155A (ja) *	2012-10-11	2015-11-19	アイエックスバイオファーマリミテッド	固体剤形

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RHODIA, MATERIAL SAFETY DATA SHEET, JPN6016039542, 30 November 2008 (2008-11-30), ISSN: 0003923981 *

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2024152150A (ja) *	2023-04-14	2024-10-25	井藤漢方製薬株式会社	口腔ケア用錠剤

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2017-12-20	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20171220
2017-12-20	A621	Written request for application examination	Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20171220
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2018-01-18	A975	Report on accelerated examination	Free format text: JAPANESE INTERMEDIATE CODE: A971005 Effective date: 20180118
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2018-04-09	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180409
2018-06-11	A02	Decision of refusal	Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20180611
2018-09-10	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180910
2018-09-19	A911	Transfer to examiner for re-examination before appeal (zenchi)	Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20180918
2018-11-26	A912	Re-examination (zenchi) completed and case transferred to appeal board	Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20181122

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EP0009853B1 (en)	1983-07-20	Dental-care device
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US6582708B1 (en)	2003-06-24	Tooth whitening substance
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Bowen	2014	24 Mechanical Oral Biofilm Control: Interdental and Supplemental Self-Care Devices
JP2001058932A (ja)	2001-03-06	歯磨

JP2017193547A - 口腔清浄用発泡性錠剤 - Google Patents

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Citations (5)

Patent Citations (5)

Non-Patent Citations (1)

Cited By (1)

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