JP2017509647A5 - - Google Patents
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- Publication number
- JP2017509647A5 JP2017509647A5 JP2016557982A JP2016557982A JP2017509647A5 JP 2017509647 A5 JP2017509647 A5 JP 2017509647A5 JP 2016557982 A JP2016557982 A JP 2016557982A JP 2016557982 A JP2016557982 A JP 2016557982A JP 2017509647 A5 JP2017509647 A5 JP 2017509647A5
- Authority
- JP
- Japan
- Prior art keywords
- activin
- item
- composition
- antibody
- gdf11
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461969073P | 2014-03-21 | 2014-03-21 | |
| US61/969,073 | 2014-03-21 | ||
| US201462021923P | 2014-07-08 | 2014-07-08 | |
| US62/021,923 | 2014-07-08 | ||
| PCT/US2015/021880 WO2015143403A1 (en) | 2014-03-21 | 2015-03-20 | Methods for increasing red blood cell levels and treating ineffective erythropoiesis by inhibiting activin b and/or gdf11 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020077142A Division JP7154250B2 (ja) | 2014-03-21 | 2020-04-24 | アクチビンｂおよび／またはｇｄｆ１１の阻害によって赤血球レベルを増大させ、無効赤血球生成を処置する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017509647A JP2017509647A (ja) | 2017-04-06 |
| JP2017509647A5 true JP2017509647A5 (2) | 2018-04-26 |
Family
ID=54145413
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016557982A Withdrawn JP2017509647A (ja) | 2014-03-21 | 2015-03-20 | アクチビンｂおよび／またはｇｄｆ１１の阻害によって赤血球レベルを増大させ、無効赤血球生成を処置する方法 |
| JP2020077142A Active JP7154250B2 (ja) | 2014-03-21 | 2020-04-24 | アクチビンｂおよび／またはｇｄｆ１１の阻害によって赤血球レベルを増大させ、無効赤血球生成を処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020077142A Active JP7154250B2 (ja) | 2014-03-21 | 2020-04-24 | アクチビンｂおよび／またはｇｄｆ１１の阻害によって赤血球レベルを増大させ、無効赤血球生成を処置する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20160046690A1 (2) |
| EP (1) | EP3119418B1 (2) |
| JP (2) | JP2017509647A (2) |
| KR (2) | KR20160127148A (2) |
| CN (1) | CN106659769A (2) |
| AU (3) | AU2015231022B2 (2) |
| CA (1) | CA2942954A1 (2) |
| MA (1) | MA39722A (2) |
| WO (1) | WO2015143403A1 (2) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| NZ707477A (en) | 2012-11-02 | 2019-09-27 | Celgene Corp | Activin-actrii antagonists and uses for treating bone and other disorders |
| US10603359B2 (en) | 2014-10-30 | 2020-03-31 | Acceleron Pharma Inc. | Methods and compositions using GDF15 polypeptides for increasing red blood cells |
| JP2018501307A (ja) | 2014-12-03 | 2018-01-18 | セルジーン コーポレイション | アクチビン−ＡｃｔＲＩＩアンタゴニスト及び貧血を治療するための使用 |
| MA41119A (fr) | 2014-12-03 | 2017-10-10 | Acceleron Pharma Inc | Méthodes de traitement de syndromes myélodysplasiques et d'anémie sidéroblastique |
| PT3286206T (pt) | 2015-04-22 | 2021-04-01 | Biogen Ma Inc | Novas proteínas híbridas bloqueadoras de ligando actriib para tratar doenças de desgaste muscular |
| US11123430B2 (en) | 2015-11-04 | 2021-09-21 | Acceleron Pharma Inc. | Methods for increasing red blood cell levels and treating ineffective erythropoiesis |
| CA3005975A1 (en) | 2015-11-23 | 2017-06-01 | Acceleron Pharma Inc. | Methods for treating eye disorders |
| PL3490582T3 (pl) * | 2016-07-27 | 2024-09-23 | Acceleron Pharma Inc. | Kompozycje do zastosowania w leczeniu mielofibrozy |
| WO2018053234A1 (en) * | 2016-09-15 | 2018-03-22 | Acceleron Pharma, Inc. | Twisted gastrulation polypeptides and uses thereof |
| JP7280182B2 (ja) * | 2016-10-05 | 2023-05-23 | アクセルロン ファーマ インコーポレイテッド | バリアントＡｃｔＲＩＩＢタンパク質およびその使用 |
| JOP20190085A1 (ar) | 2016-10-20 | 2019-04-17 | Biogen Ma Inc | طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة |
| CN110430890B (zh) | 2016-11-10 | 2024-09-10 | 科乐斯疗法公司 | 激活素受体iia型变体及其使用方法 |
| HRP20241477T1 (hr) | 2017-06-14 | 2025-01-03 | Celgene Corporation | Postupci liječenja mijeloproliferativne neoplazme povezane s mijelofibrozom i anemijom |
| CN107828719B (zh) * | 2017-09-14 | 2020-05-19 | 暨南大学 | Gdf11在脂肪间充质干细胞成骨分化中的应用 |
| EP3706777B1 (en) | 2017-11-09 | 2024-05-22 | Keros Therapeutics, Inc. | Activin receptor type iia variants and methods of use thereof |
| IL320014A (en) | 2018-01-12 | 2025-06-01 | Keros Therapeutics Inc | Activin receptor type iib variants and methods of use thereof |
| US12263205B2 (en) | 2018-04-30 | 2025-04-01 | The Children's Hospital Of Philadelphia | Methods of improving anemias by combining agents |
| JP7405772B2 (ja) | 2018-05-09 | 2023-12-26 | ケロス セラピューティクス インコーポレイテッド | アクチビンｉｉａ型受容体変異体および同変異体を含む医薬組成物 |
| CN115279392A (zh) * | 2020-01-20 | 2022-11-01 | 鲁达库尔公司 | 治疗trpv1活性介导疾病的药物组合物 |
| WO2021189010A1 (en) | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Methods of using activin receptor type iib variants |
| IL296394A (en) | 2020-03-20 | 2022-11-01 | Keros Therapeutics Inc | Type ii activin receptor chimeras and methods of using them |
| EP4514971A1 (en) * | 2022-04-29 | 2025-03-05 | University Of Massachusetts | Selective rna-modulating agents |
| CN121752722A (zh) * | 2023-08-21 | 2026-03-27 | 苏州炫景生物科技有限公司 | 靶向inhbe基因的双链寡核苷酸、缀合物、组合物及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1031674C2 (nl) * | 2005-04-25 | 2007-04-26 | Pfizer | Antilichamen tegen myostatine. |
| US8128933B2 (en) * | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| DK2124999T3 (da) * | 2006-12-18 | 2013-01-14 | Acceleron Pharma Inc | Activin-actrii antagonister og anvendelser til behandling af anæmi |
| SMT202300222T1 (it) * | 2008-08-14 | 2023-09-06 | Acceleron Pharma Inc | Trappole di gdf |
| US8216997B2 (en) * | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| BRPI1010587A2 (pt) * | 2009-06-08 | 2019-04-09 | Acceleron Pharma Inc. | métodos para aumentar adipócitos termogênicos |
| KR20180085825A (ko) | 2009-08-13 | 2018-07-27 | 악셀레론 파마 인코포레이티드 | 적혈구 수준을 증가시키기 위한 ｇｄｆ 트랩과 에리트로포이에틴 수용체 활성인자의 병용 |
| WO2012027065A2 (en) * | 2010-08-27 | 2012-03-01 | Celgene Corporation | Combination therapy for treatment of disease |
| BR112014009528B1 (pt) * | 2011-10-17 | 2020-12-29 | Acceleron Pharma, Inc. | usos de polipeptídeos actriib para a fabricação de um medicamento para tratar eritropoiese ineficaz |
| EP2844668A1 (en) * | 2012-05-03 | 2015-03-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method and pharmaceutical composition for use in the treatment and diagnotic of anemia of inflammation |
| AU2013334660B2 (en) * | 2012-10-24 | 2018-08-09 | Celgene Corporation | Methods for treating anemia |
-
2015
- 2015-03-20 MA MA039722A patent/MA39722A/fr unknown
- 2015-03-20 AU AU2015231022A patent/AU2015231022B2/en not_active Ceased
- 2015-03-20 KR KR1020167029253A patent/KR20160127148A/ko not_active Ceased
- 2015-03-20 CN CN201580024704.5A patent/CN106659769A/zh active Pending
- 2015-03-20 US US14/664,651 patent/US20160046690A1/en not_active Abandoned
- 2015-03-20 JP JP2016557982A patent/JP2017509647A/ja not_active Withdrawn
- 2015-03-20 KR KR1020227044659A patent/KR102520970B1/ko active Active
- 2015-03-20 CA CA2942954A patent/CA2942954A1/en active Pending
- 2015-03-20 EP EP15765863.4A patent/EP3119418B1/en active Active
- 2015-03-20 WO PCT/US2015/021880 patent/WO2015143403A1/en not_active Ceased
-
2020
- 2020-04-24 JP JP2020077142A patent/JP7154250B2/ja active Active
- 2020-07-02 US US16/919,377 patent/US20210155672A1/en not_active Abandoned
-
2021
- 2021-01-19 AU AU2021200301A patent/AU2021200301A1/en not_active Abandoned
-
2023
- 2023-08-23 AU AU2023219885A patent/AU2023219885A1/en not_active Abandoned
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