JP2017519483A5 - - Google Patents

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Publication number
JP2017519483A5
JP2017519483A5 JP2016561296A JP2016561296A JP2017519483A5 JP 2017519483 A5 JP2017519483 A5 JP 2017519483A5 JP 2016561296 A JP2016561296 A JP 2016561296A JP 2016561296 A JP2016561296 A JP 2016561296A JP 2017519483 A5 JP2017519483 A5 JP 2017519483A5
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JP
Japan
Prior art keywords
transgenic
porcine
cells
islets
diabetes
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JP2016561296A
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English (en)
Japanese (ja)
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JP2017519483A (ja
JP6621420B2 (ja
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Priority claimed from PCT/EP2015/057914 external-priority patent/WO2015155360A1/en
Publication of JP2017519483A publication Critical patent/JP2017519483A/ja
Publication of JP2017519483A5 publication Critical patent/JP2017519483A5/ja
Application granted granted Critical
Publication of JP6621420B2 publication Critical patent/JP6621420B2/ja
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JP2016561296A 2014-04-11 2015-04-10 糖尿病を治療するためのトランスジェニックブタ膵島およびその使用 Active JP6621420B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14164372 2014-04-11
EP14164372.6 2014-04-11
EP14199910.2 2014-12-22
EP14199910 2014-12-22
PCT/EP2015/057914 WO2015155360A1 (en) 2014-04-11 2015-04-10 Transgenic pig islets and uses thereof for treating diabetes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019208487A Division JP2020048565A (ja) 2014-04-11 2019-11-19 糖尿病を治療するためのトランスジェニックブタ膵島およびその使用

Publications (3)

Publication Number Publication Date
JP2017519483A JP2017519483A (ja) 2017-07-20
JP2017519483A5 true JP2017519483A5 (2) 2018-05-24
JP6621420B2 JP6621420B2 (ja) 2019-12-18

Family

ID=52823655

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016561296A Active JP6621420B2 (ja) 2014-04-11 2015-04-10 糖尿病を治療するためのトランスジェニックブタ膵島およびその使用
JP2019208487A Pending JP2020048565A (ja) 2014-04-11 2019-11-19 糖尿病を治療するためのトランスジェニックブタ膵島およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019208487A Pending JP2020048565A (ja) 2014-04-11 2019-11-19 糖尿病を治療するためのトランスジェニックブタ膵島およびその使用

Country Status (10)

Country Link
US (2) US11160836B2 (2)
EP (2) EP3129467B1 (2)
JP (2) JP6621420B2 (2)
CN (1) CN106456674B (2)
CA (1) CA2945240C (2)
DK (1) DK3129467T3 (2)
ES (1) ES2769813T3 (2)
PL (1) PL3129467T3 (2)
PT (1) PT3129467T (2)
WO (1) WO2015155360A1 (2)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3129467T3 (pl) * 2014-04-11 2020-05-18 Université Catholique de Louvain Wysepki od świni transgenicznej i ich zastosowania w leczeniu cukrzycy
EP3745404B1 (en) 2019-05-29 2024-04-03 Cell Networks GmbH Method and system for predicting coupling probabilities of g-protein coupled receptors with g-proteins
EP3789765A1 (en) * 2019-09-09 2021-03-10 ETH Zürich A method for evaluating damage of solid tissue
CN115152693A (zh) * 2021-11-22 2022-10-11 兰州大学 一种小鼠2型糖尿病模型的构建及评价方法
CN115569194B (zh) * 2022-10-28 2026-02-27 陕西中鸿科瑞再生医学研究院有限公司 一种具有糖尿病治疗作用的温敏水凝胶、试剂盒、使用方法及其应用
WO2025202874A1 (en) * 2024-03-25 2025-10-02 Crispr Therapeutics Ag Genetically modified cells expressing glp-1 receptor agonist
CN118787658B (zh) * 2024-06-14 2025-01-21 中国农业大学 一种胰高血糖素样肽-1受体特异性核酸适配体在代谢疾病干预中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA65549C2 (uk) * 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
US7094593B1 (en) * 1998-09-01 2006-08-22 Basf Aktiengesellschaft Method for improving the function of heterologous G protein-coupled receptors
EP1333846B1 (en) 2000-10-17 2012-04-18 Diabcell Pty Limited Preparation and xenotransplantation or porcine islets
FR2820057A1 (fr) 2001-01-30 2002-08-02 Ct De Transfert De Technologie Membrane pour chambre d'encapsulation de cellules produisant au moins une substance biologiquement active et organe bio-artificiel comprenant une telle membrane
NZ539491A (en) 2005-04-15 2008-04-30 Living Cell Products Pty Ltd Swine population and uses thereof
CA2625875C (en) 2005-10-21 2013-12-24 Living Cell Products Pty Limited Encapsulation system
ES2386123T3 (es) 2006-06-16 2012-08-09 Fmc Biopolymer As Dispositivo celular con una matriz de colágeno revestida de alginato, proceso para su formación y utilizaciones
US9540630B2 (en) 2008-09-17 2017-01-10 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
ES2767881T3 (es) 2009-08-14 2020-06-18 Revivicor Inc Cerdos multi-transgénicos para el tratamiento de diabetes
US20140017678A1 (en) * 2012-06-11 2014-01-16 Nodality, Inc. Pathway characterization of cells
US20130336940A1 (en) * 2011-02-23 2013-12-19 Universite Catholique De Louvain Modified pig islets for diabetes treatment
UY34347A (es) * 2011-09-26 2013-04-30 Novartis Ag Proteínas de función dual para tratar trastornos metabólicos
PL3129467T3 (pl) * 2014-04-11 2020-05-18 Université Catholique de Louvain Wysepki od świni transgenicznej i ich zastosowania w leczeniu cukrzycy

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