JP2017520583A5 - - Google Patents

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Publication number: JP2017520583A5
Authority: JP; Japan
Prior art keywords: composition; use according; asc; sepsis; administered
Prior art date: 2015-06-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP2016575950A

Other languages

English (en)

Japanese (ja)

Other versions

JP6722599B2 (ja

JP2017520583A (ja

Filing date

2015-06-30

Publication date

2018-08-09

2015-06-30 Application filed filed Critical

2015-06-30 Priority claimed from PCT/IB2015/054923 external-priority patent/WO2016001846A1/en

2017-07-27 Publication of JP2017520583A publication Critical patent/JP2017520583A/ja

2018-08-09 Publication of JP2017520583A5 publication Critical patent/JP2017520583A5/ja

2020-07-15 Application granted granted Critical

2020-07-15 Publication of JP6722599B2 publication Critical patent/JP6722599B2/ja

Status Active legal-status Critical Current

2035-06-30 Anticipated expiration legal-status Critical

Links

210000002536 stromal cell Anatomy 0.000 claims description 16
206010040047 Sepsis Diseases 0.000 claims description 13
210000000577 adipose tissue Anatomy 0.000 claims description 7
-1 CD49A Proteins 0.000 claims description 6
210000004027 cell Anatomy 0.000 claims description 5
230000002757 inflammatory effect Effects 0.000 claims description 5
210000004072 lung Anatomy 0.000 claims description 5
101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims description 4
102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims description 4
239000003814 drug Substances 0.000 claims description 4
206010035664 Pneumonia Diseases 0.000 claims description 3
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108010085238 Actins Proteins 0.000 claims description 2
102100022749 Aminopeptidase N Human genes 0.000 claims description 2
102100032912 CD44 antigen Human genes 0.000 claims description 2
102100022002 CD59 glycoprotein Human genes 0.000 claims description 2
102100037904 CD9 antigen Human genes 0.000 claims description 2
102100025680 Complement decay-accelerating factor Human genes 0.000 claims description 2
102100036912 Desmin Human genes 0.000 claims description 2
108010044052 Desmin Proteins 0.000 claims description 2
102100037241 Endoglin Human genes 0.000 claims description 2
102000001690 Factor VIII Human genes 0.000 claims description 2
108010054218 Factor VIII Proteins 0.000 claims description 2
102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims description 2
101000757160 Homo sapiens Aminopeptidase N Proteins 0.000 claims description 2
101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims description 2
101000897400 Homo sapiens CD59 glycoprotein Proteins 0.000 claims description 2
101000738354 Homo sapiens CD9 antigen Proteins 0.000 claims description 2
101000856022 Homo sapiens Complement decay-accelerating factor Proteins 0.000 claims description 2
101000881679 Homo sapiens Endoglin Proteins 0.000 claims description 2
101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims description 2
101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 claims description 2
101001046677 Homo sapiens Integrin alpha-V Proteins 0.000 claims description 2
101000935043 Homo sapiens Integrin beta-1 Proteins 0.000 claims description 2
101000599852 Homo sapiens Intercellular adhesion molecule 1 Proteins 0.000 claims description 2
101001063392 Homo sapiens Lymphocyte function-associated antigen 3 Proteins 0.000 claims description 2
101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims description 2
101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims description 2
102100022338 Integrin alpha-M Human genes 0.000 claims description 2
102100022337 Integrin alpha-V Human genes 0.000 claims description 2
102100022297 Integrin alpha-X Human genes 0.000 claims description 2
102100025304 Integrin beta-1 Human genes 0.000 claims description 2
102100037877 Intercellular adhesion molecule 1 Human genes 0.000 claims description 2
102000011782 Keratins Human genes 0.000 claims description 2
108010076876 Keratins Proteins 0.000 claims description 2
102100030984 Lymphocyte function-associated antigen 3 Human genes 0.000 claims description 2
102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims description 2
102000003729 Neprilysin Human genes 0.000 claims description 2
108090000028 Neprilysin Proteins 0.000 claims description 2
102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims description 2
102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims description 2
230000000735 allogeneic effect Effects 0.000 claims description 2
210000005045 desmin Anatomy 0.000 claims description 2
239000003085 diluting agent Substances 0.000 claims description 2
239000003937 drug carrier Substances 0.000 claims description 2
229960000301 factor viii Drugs 0.000 claims description 2
238000007917 intracranial administration Methods 0.000 claims description 2
238000007918 intramuscular administration Methods 0.000 claims description 2
238000007919 intrasynovial administration Methods 0.000 claims description 2
238000007913 intrathecal administration Methods 0.000 claims description 2
238000001990 intravenous administration Methods 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 claims description 2
238000007920 subcutaneous administration Methods 0.000 claims description 2
229940124597 therapeutic agent Drugs 0.000 claims description 2
102100038021 Steryl-sulfatase Human genes 0.000 claims 8
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210000004271 bone marrow stromal cell Anatomy 0.000 description 7
210000000130 stem cell Anatomy 0.000 description 2
GNENVASJJIUNER-UHFFFAOYSA-N 2,4,6-tricyclohexyloxy-1,3,5,2,4,6-trioxatriborinane Chemical compound C1CCCCC1OB1OB(OC2CCCCC2)OB(OC2CCCCC2)O1 GNENVASJJIUNER-UHFFFAOYSA-N 0.000 description 1
208000022120 Jeavons syndrome Diseases 0.000 description 1
230000037396 body weight Effects 0.000 description 1
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230000035899 viability Effects 0.000 description 1

JP2016575950A 2014-06-30 2015-06-30 全身性炎症反応症候群の治療のための間葉系間質細胞 Active JP6722599B2 (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP14175095		2014-06-30
EP14175095.0		2014-06-30
PCT/IB2015/054923 WO2016001846A1 (en)	2014-06-30	2015-06-30	Mesenchymal stromal cells for treating sepsis

Publications (3)

Publication Number	Publication Date
JP2017520583A JP2017520583A (ja)	2017-07-27
JP2017520583A5 true JP2017520583A5 (2)	2018-08-09
JP6722599B2 JP6722599B2 (ja)	2020-07-15

Family

ID=51033023

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2016575950A Active JP6722599B2 (ja)	2014-06-30	2015-06-30	全身性炎症反応症候群の治療のための間葉系間質細胞

Country Status (14)

Country	Link
US (2)	US20170151284A1 (2)
EP (1)	EP3160481B1 (2)
JP (1)	JP6722599B2 (2)
KR (1)	KR102213527B1 (2)
CN (1)	CN106573017B (2)
AU (1)	AU2015283662B2 (2)
BR (1)	BR112016030758B8 (2)
CA (1)	CA2953884C (2)
IL (1)	IL249814B (2)
MX (1)	MX381544B (2)
NZ (1)	NZ727950A (2)
RU (1)	RU2715866C2 (2)
SG (1)	SG11201610844PA (2)
WO (1)	WO2016001846A1 (2)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP6714932B2 (ja) *	2015-12-01	2020-07-01	株式会社ＡｄｉｐｏＳｅｅｄｓ	脊椎動物の脂肪組織由来間葉系細胞株の製造方法
WO2017156235A1 (en) *	2016-03-09	2017-09-14	Emory University	Methods of preserving mesenchymal stem cells
GB201604304D0 (en) *	2016-03-14	2016-04-27	Tigenix S A U	Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease
AU2018228352B2 (en)	2017-02-28	2024-08-01	Centre Hospitalier Régional Universitaire De Nancy	Mesenchymal stem cells obtained from Wharton's jelly for the treatment of sepsis
WO2019084010A1 (en)	2017-10-26	2019-05-02	Emory University	MCL-1 INHIBITORS, COMPOSITIONS AND USES IN CANCER CARE
US20210228637A1 (en) *	2018-06-05	2021-07-29	Medipost Co., Ltd	Pharmaceutical composition comprising hyaluronic acid and stem cells for treating cartilage damage-associated disease
US20220010281A1 (en) *	2018-10-29	2022-01-13	Ottawa Hospital Research Institute	Genetically-engineered mesenchymal stem cells overexpressing aoah and uses thereof
EP4098267A4 (en) *	2020-01-30	2024-03-06	JCR Pharmaceuticals Co., Ltd.	MEDICINAL COMPOSITION COMPRISING CELLS DERIVED FROM DENTAL PULP
JP2024517954A (ja) *	2021-05-13	2024-04-23	プライムジェンユーエスインコーポレイテッド	肝疾患を治療するための方法および組成物
CN113398150A (zh) *	2021-06-18	2021-09-17	卡替(上海)生物技术有限公司	牙髓间充质干细胞在脓毒症治疗中的应用

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US5578475A (en)	1993-07-12	1996-11-26	Life Technologies, Inc.	Composition and methods for transfecting eukaryotic cells
US5976567A (en)	1995-06-07	1999-11-02	Inex Pharmaceuticals Corp.	Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
US6051429A (en)	1995-06-07	2000-04-18	Life Technologies, Inc.	Peptide-enhanced cationic lipid transfections
US5744335A (en)	1995-09-19	1998-04-28	Mirus Corporation	Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
US5705308A (en)	1996-09-30	1998-01-06	Eastman Kodak Company	Infrared-sensitive, negative-working diazonaphthoquinone imaging composition and element
US6777231B1 (en)	1999-03-10	2004-08-17	The Regents Of The University Of California	Adipose-derived stem cells and lattices
EP3461884B1 (en)	2004-03-22	2025-05-28	Mesoblast International Sàrl	Mesenchymal stem cells and uses therefor
KR101536239B1 (ko)	2005-09-23	2015-07-13	셀레릭스, 에스.엘.	면역조절활성을 갖는 세포 개체군, 분리 방법 및 용도
GB0814249D0 (en) *	2008-08-04	2008-09-10	Cellerix Sa	Uses of mesenchymal stem cells
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JP2014016782A (ja) *	2012-07-09	2014-01-30	Toshiba Corp	情報処理装置およびプログラム
US20140134140A1 (en) *	2012-11-09	2014-05-15	Case Western Reserve University	Mesenchymal stem cell compositions for the treatment of microbial infections

2015
- 2015-06-30 JP JP2016575950A patent/JP6722599B2/ja active Active
- 2015-06-30 EP EP15742102.5A patent/EP3160481B1/en active Active
- 2015-06-30 CA CA2953884A patent/CA2953884C/en active Active
- 2015-06-30 BR BR112016030758A patent/BR112016030758B8/pt active IP Right Grant
- 2015-06-30 US US15/323,373 patent/US20170151284A1/en not_active Abandoned
- 2015-06-30 CN CN201580042833.7A patent/CN106573017B/zh active Active
- 2015-06-30 MX MX2017000142A patent/MX381544B/es unknown
- 2015-06-30 SG SG11201610844PA patent/SG11201610844PA/en unknown
- 2015-06-30 AU AU2015283662A patent/AU2015283662B2/en active Active
- 2015-06-30 WO PCT/IB2015/054923 patent/WO2016001846A1/en not_active Ceased
- 2015-06-30 NZ NZ727950A patent/NZ727950A/en unknown
- 2015-06-30 KR KR1020177002380A patent/KR102213527B1/ko active Active
- 2015-06-30 RU RU2016151738A patent/RU2715866C2/ru active
2016
- 2016-12-28 IL IL249814A patent/IL249814B/en active IP Right Grant
2020
- 2020-08-14 US US16/994,379 patent/US20200376038A1/en not_active Abandoned

Publication	Publication Date	Title
JP2017520583A5 (2)	2018-08-09
Han et al.	2022	The secretion profile of mesenchymal stem cells and potential applications in treating human diseases
JP2016523285A5 (2)	2017-08-03
RU2010153362A (ru)	2012-07-10	Способы лечения воспалительных заболеваний ободочной кишки
Malgieri et al.	2010	Bone marrow and umbilical cord blood human mesenchymal stem cells: state of the art
RU2016151738A (ru)	2018-07-30	Мезенхимальные стромальные клетки для лечения синдрома системной воспалительной реакции
Ejtehadifar et al.	2015	The effect of hypoxia on mesenchymal stem cell biology
Li et al.	2013	Bone‐marrow‐derived mesenchymal stem cells for organ repair
Zhao et al.	2016	The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation
JP2014509319A5 (2)	2015-03-05
JP2014000094A5 (ja)	2014-07-10	臍帯由来細胞を用いた局部的または散在的脳外傷の改善
JP2008546397A5 (2)	2012-07-26
MX2019003936A (es)	2019-06-10	Metodo para aislar celulas madre mesenquimales a partir de membrana amniotica de cordon umbilical utilizando un medio de cultivo celular.
JP2014208682A5 (2)	2015-07-09
RU2015141314A (ru)	2018-12-26	Адгезивные клетки жировой ткани или плаценты и их использование в лечебных целях
El-Haibi et al.	2010	Mesenchymal stem cells in the pathogenesis and therapy of breast cancer
RU2013141914A (ru)	2015-03-27	Лечение амиотрофического бокового склероза с использованием полученных из пуповины клеток
JP2017520582A5 (2)	2018-08-09
RU2014108878A (ru)	2015-09-20	Лечение заболевания периферических сосудов при помощи клеток, полученных из ткани пуповины
JP2019508455A5 (2)	2020-04-23
Zhang et al.	2012	Effects of Rehmannia glutinosa oligosaccharide on human adipose-derived mesenchymal stem cells in vitro
Götherström	2016	Human foetal mesenchymal stem cells
WO2012033352A3 (ko)	2012-06-28	말과동물 양수 유래 다분화능 줄기세포 및 그 제조방법
Solali et al.	2015	Isolation and characterization of mesenchymal stem cells derived from adipose tissue
Pershina et al.	2012	MSCs of pulmonary in Bleomycin-induced Pulmonary Fibrosis