JP4346438B2 - 緑内障および老眼の治療のための方法および強膜内インプラント - Google Patents
緑内障および老眼の治療のための方法および強膜内インプラント Download PDFInfo
- Publication number
- JP4346438B2 JP4346438B2 JP2003520429A JP2003520429A JP4346438B2 JP 4346438 B2 JP4346438 B2 JP 4346438B2 JP 2003520429 A JP2003520429 A JP 2003520429A JP 2003520429 A JP2003520429 A JP 2003520429A JP 4346438 B2 JP4346438 B2 JP 4346438B2
- Authority
- JP
- Japan
- Prior art keywords
- implant
- body portion
- intrascleral
- medication
- reservoir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007943 implant Substances 0.000 title claims description 83
- 201000010041 presbyopia Diseases 0.000 title claims description 15
- 238000000034 method Methods 0.000 title description 22
- 238000011282 treatment Methods 0.000 title description 9
- 208000010412 Glaucoma Diseases 0.000 title description 7
- 239000003814 drug Substances 0.000 claims description 29
- 229940079593 drug Drugs 0.000 claims description 24
- 230000004410 intraocular pressure Effects 0.000 claims description 22
- 210000003786 sclera Anatomy 0.000 claims description 22
- 238000000576 coating method Methods 0.000 claims description 7
- 238000002513 implantation Methods 0.000 claims description 7
- 239000011248 coating agent Substances 0.000 claims description 6
- 210000001508 eye Anatomy 0.000 description 52
- 230000004438 eyesight Effects 0.000 description 15
- 239000012530 fluid Substances 0.000 description 9
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- 238000003780 insertion Methods 0.000 description 2
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- 210000001747 pupil Anatomy 0.000 description 2
- 229910052715 tantalum Inorganic materials 0.000 description 2
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 2
- ZYSIKFURCZVRMP-UHFFFAOYSA-N CS1CCCC1 Chemical compound CS1CCCC1 ZYSIKFURCZVRMP-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Surgery (AREA)
- Prostheses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31002701P | 2001-08-03 | 2001-08-03 | |
| PCT/US2002/024646 WO2003015667A1 (fr) | 2001-08-03 | 2002-08-02 | Methode et implant intra-scleral pour le traitement du glaucome et de la presbyopie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005508213A JP2005508213A (ja) | 2005-03-31 |
| JP4346438B2 true JP4346438B2 (ja) | 2009-10-21 |
Family
ID=33510228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003520429A Expired - Fee Related JP4346438B2 (ja) | 2001-08-03 | 2002-08-02 | 緑内障および老眼の治療のための方法および強膜内インプラント |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1418864A4 (fr) |
| JP (1) | JP4346438B2 (fr) |
| KR (1) | KR20040024873A (fr) |
| CA (1) | CA2455120A1 (fr) |
| IL (1) | IL160037A0 (fr) |
| WO (1) | WO2003015667A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014087650A (ja) * | 2006-03-31 | 2014-05-15 | Qlt Inc | 薬物治療用鼻涙排液系インプラント |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040225250A1 (en) | 2003-05-05 | 2004-11-11 | Michael Yablonski | Internal shunt and method for treating glaucoma |
| US7291125B2 (en) | 2003-11-14 | 2007-11-06 | Transcend Medical, Inc. | Ocular pressure regulation |
| AU2005338015C1 (en) * | 2005-10-31 | 2010-11-18 | Life Spring Biotech Co., Ltd. | Scleral buckle band and method for making it |
| EP1979023B1 (fr) | 2006-01-17 | 2015-07-22 | Transcend Medical, Inc. | Dispositif de traitement de glaucome |
| EP1978892B1 (fr) | 2006-01-17 | 2017-11-15 | Novartis Ag | Dispositif de traitement d'administration de medicament |
| ES2964952T3 (es) * | 2006-07-11 | 2024-04-10 | Refocus Group Inc | Prótesis escleral para el tratamiento de la presbicia y otros trastornos oculares |
| WO2009012406A1 (fr) | 2007-07-17 | 2009-01-22 | Transcend Medical, Inc. | Implant oculaire avec référence de capacités d'expansion d'hydrogel pour document prioritaire |
| JP5323073B2 (ja) * | 2007-08-02 | 2013-10-23 | リフォーカス グループ、インコーポレイテッド | 老眼及び他の眼疾患を治療するためのクロスバーを有する強膜プロテーゼ |
| DE102008021842A1 (de) | 2008-04-30 | 2009-11-05 | Tesa Se | Polyolefinfolie und Verwendung derselben |
| US8617139B2 (en) | 2008-06-25 | 2013-12-31 | Transcend Medical, Inc. | Ocular implant with shape change capabilities |
| GB2464981A (en) * | 2008-11-01 | 2010-05-05 | Univ Dundee | Pressure sensor for measuring intraocular pressure that can be worn on the eye. |
| EP3735947B1 (fr) | 2009-01-28 | 2022-05-04 | Alcon Inc. | Système d'implantation pour un implant oculaire |
| US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
| WO2011155916A1 (fr) * | 2010-06-11 | 2011-12-15 | Damiano Richard E | Dispositif d'amélioration pour la lecture pour prévenir et traiter la presbytie de l'œil |
| WO2013011511A1 (fr) | 2011-07-18 | 2013-01-24 | Mor Research Applications Ltd. | Dispositif pour l'ajustement de la tension intraoculaire |
| US10085633B2 (en) | 2012-04-19 | 2018-10-02 | Novartis Ag | Direct visualization system for glaucoma treatment |
| US9241832B2 (en) | 2012-04-24 | 2016-01-26 | Transcend Medical, Inc. | Delivery system for ocular implant |
| EP2895123B1 (fr) | 2012-09-17 | 2017-06-07 | Novartis Ag | Dispositifs d'implant oculaire expansible |
| US9763829B2 (en) | 2012-11-14 | 2017-09-19 | Novartis Ag | Flow promoting ocular implant |
| US9987163B2 (en) | 2013-04-16 | 2018-06-05 | Novartis Ag | Device for dispensing intraocular substances |
| EP3541323A4 (fr) * | 2016-12-23 | 2020-08-05 | Refocus Group, Inc. | Prothèse sclérale à surface(s) dentelée(s) ou autre(s) destinée à être retenue dans un tissu scléral, destinée à traiter la presbytie |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5322691A (en) * | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions |
| US4863457A (en) * | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US4946436A (en) * | 1989-11-17 | 1990-08-07 | Smith Stewart G | Pressure-relieving device and process for implanting |
| US5178604A (en) | 1990-05-31 | 1993-01-12 | Iovision, Inc. | Glaucoma implant |
| US5466233A (en) * | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
| US6102045A (en) | 1994-07-22 | 2000-08-15 | Premier Laser Systems, Inc. | Method and apparatus for lowering the intraocular pressure of an eye |
| US5558630A (en) * | 1994-12-30 | 1996-09-24 | Fisher; Bret L. | Intrascleral implant and method for the regulation of intraocular pressure |
| US5968058A (en) * | 1996-03-27 | 1999-10-19 | Optonol Ltd. | Device for and method of implanting an intraocular implant |
| US6007578A (en) | 1997-10-08 | 1999-12-28 | Ras Holding Corp | Scleral prosthesis for treatment of presbyopia and other eye disorders |
| US6079417A (en) | 1999-03-23 | 2000-06-27 | Fugo; Richard J. | Method of altering the shape of the cornea of the eye |
-
2002
- 2002-08-02 KR KR10-2004-7001249A patent/KR20040024873A/ko not_active Ceased
- 2002-08-02 JP JP2003520429A patent/JP4346438B2/ja not_active Expired - Fee Related
- 2002-08-02 EP EP02768411A patent/EP1418864A4/fr not_active Withdrawn
- 2002-08-02 IL IL16003702A patent/IL160037A0/xx unknown
- 2002-08-02 CA CA002455120A patent/CA2455120A1/fr not_active Abandoned
- 2002-08-02 WO PCT/US2002/024646 patent/WO2003015667A1/fr not_active Ceased
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014087650A (ja) * | 2006-03-31 | 2014-05-15 | Qlt Inc | 薬物治療用鼻涙排液系インプラント |
| US12226525B2 (en) | 2006-03-31 | 2025-02-18 | Mati Therapeutics, Inc. | Nasolacrimal drainage system implants for drug therapy |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1418864A4 (fr) | 2009-07-01 |
| WO2003015667A8 (fr) | 2004-12-16 |
| JP2005508213A (ja) | 2005-03-31 |
| CA2455120A1 (fr) | 2003-02-27 |
| KR20040024873A (ko) | 2004-03-22 |
| WO2003015667A1 (fr) | 2003-02-27 |
| EP1418864A1 (fr) | 2004-05-19 |
| IL160037A0 (en) | 2004-06-20 |
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