JP4361684B2 - エリトロポエチン受容体のためのペプチドリガンド - Google Patents

エリトロポエチン受容体のためのペプチドリガンド Download PDF

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Publication number
JP4361684B2
JP4361684B2 JP2000536391A JP2000536391A JP4361684B2 JP 4361684 B2 JP4361684 B2 JP 4361684B2 JP 2000536391 A JP2000536391 A JP 2000536391A JP 2000536391 A JP2000536391 A JP 2000536391A JP 4361684 B2 JP4361684 B2 JP 4361684B2
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Japan
Prior art keywords
sequence
seq
amino acid
epor
binding
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Expired - Fee Related
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JP2000536391A
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English (en)
Japanese (ja)
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JP2002506828A (ja
Inventor
ジェイ． マッコーネル，スティーブン
ジー． スパイネラ，ドミニク
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Chugai Pharmaceutical Co Ltd
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Chugai Pharmaceutical Co Ltd
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Publication of JP2002506828A publication Critical patent/JP2002506828A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000536391A 1998-03-20 1999-03-17 エリトロポエチン受容体のためのペプチドリガンド Expired - Fee Related JP4361684B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7878498P 1998-03-20 1998-03-20
US60/078,784 1998-03-20
PCT/US1999/005842 WO1999047151A1 (fr) 1998-03-20 1999-03-17 Ligands peptidiques pour recepteur d'erythropoietine

Publications (2)

Publication Number Publication Date
JP2002506828A JP2002506828A (ja) 2002-03-05
JP4361684B2 true JP4361684B2 (ja) 2009-11-11

Family

ID=22146200

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000536391A Expired - Fee Related JP4361684B2 (ja) 1998-03-20 1999-03-17 エリトロポエチン受容体のためのペプチドリガンド

Country Status (3)

Country Link
JP (1) JP4361684B2 (fr)
AU (1) AU3189299A (fr)
WO (1) WO1999047151A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
PT1783222E (pt) 1998-10-23 2012-07-26 Kirin Amgen Inc Péptidos diméricos de trombopoietina que simulam a ligação ao receptor mpl e têm actividade trombopoiética
WO2006010057A2 (fr) 2004-07-08 2006-01-26 Amgen Inc. Peptides therapeutiques
EA011879B1 (ru) 2004-09-24 2009-06-30 Эмджин Инк. МОЛЕКУЛЫ С МОДИФИЦИРОВАННЫМ Fc ФРАГМЕНТОМ
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US9283260B2 (en) 2006-04-21 2016-03-15 Amgen Inc. Lyophilized therapeutic peptibody formulations
CN110361535A (zh) * 2018-04-09 2019-10-22 宁夏医科大学总医院 检测促红细胞生成素受体的放射性探针、制备方法及应用

Also Published As

Publication number Publication date
AU3189299A (en) 1999-10-11
WO1999047151A1 (fr) 1999-09-23
JP2002506828A (ja) 2002-03-05

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