JP4472991B2 - 対象の研究方法およびその光学干渉計(変型) - Google Patents
対象の研究方法およびその光学干渉計(変型) Download PDFInfo
- Publication number
- JP4472991B2 JP4472991B2 JP2003568347A JP2003568347A JP4472991B2 JP 4472991 B2 JP4472991 B2 JP 4472991B2 JP 2003568347 A JP2003568347 A JP 2003568347A JP 2003568347 A JP2003568347 A JP 2003568347A JP 4472991 B2 JP4472991 B2 JP 4472991B2
- Authority
- JP
- Japan
- Prior art keywords
- optical
- optical radiation
- low coherence
- radiation
- low
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000003287 optical effect Effects 0.000 title claims description 413
- 238000000034 method Methods 0.000 title claims description 44
- 238000011160 research Methods 0.000 title description 11
- 230000005855 radiation Effects 0.000 claims description 191
- 238000005259 measurement Methods 0.000 claims description 56
- 239000000523 sample Substances 0.000 claims description 29
- 239000013307 optical fiber Substances 0.000 claims description 28
- 230000010287 polarization Effects 0.000 claims description 21
- 238000013507 mapping Methods 0.000 claims description 7
- 230000001427 coherent effect Effects 0.000 claims description 5
- 230000035945 sensitivity Effects 0.000 claims description 4
- 230000002457 bidirectional effect Effects 0.000 claims description 3
- 238000012014 optical coherence tomography Methods 0.000 description 8
- 230000008859 change Effects 0.000 description 7
- 238000003745 diagnosis Methods 0.000 description 7
- 239000006185 dispersion Substances 0.000 description 7
- 238000012545 processing Methods 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 238000003384 imaging method Methods 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 6
- 238000009826 distribution Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000000835 fiber Substances 0.000 description 5
- 210000000056 organ Anatomy 0.000 description 5
- 230000002441 reversible effect Effects 0.000 description 5
- 238000001727 in vivo Methods 0.000 description 4
- 238000009434 installation Methods 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 239000013589 supplement Substances 0.000 description 4
- 210000001835 viscera Anatomy 0.000 description 4
- 238000001839 endoscopy Methods 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- -1 catheter Substances 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 229940020445 flector Drugs 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000002310 reflectometry Methods 0.000 description 2
- 239000004065 semiconductor Substances 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 230000000153 supplemental effect Effects 0.000 description 2
- 241000975394 Evechinus chloroticus Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000237503 Pectinidae Species 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 230000003760 hair shine Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000005305 interferometry Methods 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 235000020637 scallop Nutrition 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
- G01B9/02011—Interferometers characterised by controlling or generating intrinsic radiation properties using temporal polarization variation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
- G01B9/02002—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02015—Interferometers characterised by the beam path configuration
- G01B9/02027—Two or more interferometric channels or interferometers
- G01B9/02028—Two or more reference or object arms in one interferometer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/0209—Low-coherence interferometers
- G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/45—Multiple detectors for detecting interferometer signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/70—Using polarization in the interferometer
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Instruments For Measurement Of Length By Optical Means (AREA)
- Variable-Direction Aerials And Aerial Arrays (AREA)
Description
ν=dΔ/dt,
ν−光学長の差(Δ)の速度
λ−線源(1)の中央の波長
2 第1の光ビームスプリッター
3,22 測定腕
4,23 支持腕
5,21,24 光ビームスプリッター
6,16,25,28 第1ポート
7,11,26,29 第2ポート
8,27 対象
9,10,32,34 第3ポート
12,15,30,31 第4ポート
13,14,33,35 光受信器
17,18,36,37 光学遅延線
19,38 探針
Claims (12)
- 対象(人体を除く)を研究する方法であって、
低干渉性光学放射を形成する段階と、
前記低干渉性光学放射を第1の低干渉性光学放射のビームおよび第2の低干渉性光学放射のビームに分ける段階と、
前記第1の低干渉性光学放射のビームを測定光路に沿って伝える段階と、
前記第2の低干渉性光学放射のビームを支持光路に沿って伝える段階と、
前記測定光路を伝わって通過した低干渉性光学放射を、前記支持光路を伝わって通過した低干渉性光学放射と混合する段階と、
前記混合の結果である光学放射の干渉強度変調の少なくとも一つの信号を利用して、研究する対象についてのインフォメーションを持ち測定光路を伝わって透過した低干渉性光学放射の強度を写像する段階とを備え、
前記支持光路がループ状に形成され、
前記第1の低干渉性光学放射のビームが第3の低干渉性光学放射のビームおよび第4の低干渉性光学放射のビームに分けられ、
前記第3の低干渉性光学放射のビームが前記対象に向けられ、
前記第4の低干渉性光学放射のビームが時計回りに前記支持光路のループに向けられ、
前記第2の低干渉性光学放射のビームが反時計回りに前記支持光路のループに向けられ、
前記第3の低干渉性光学放射のビームが双方向性の測定光路を前向きおよび後ろ向きに前記測定光路に沿って伝わり、
前記対象から戻ってきた低干渉性光学放射が、反時計回りに前記支持光路を通過した前記第2の低干渉性光学放射のビームと混合され、
前記混合の結果である光学放射の部分が時計回りに前記支持光路を通過した前記第4の低干渉性光学放射のビームと混合されることを特徴とする方法。 - 光学放射線源と、第1の光ビームスプリッターと、測定腕と、支持腕と、第2の光ビームスプリッターと、少なくとも一つの光受信器とを備えた光学干渉計であって、
前記測定腕が双方向性であり、前記第2の光ビームスプリッターの一つに接続されていて、
前記支持腕が前記第1の光ビームスプリッターのポートの一つから前記第2の光ビームスプリッターのポートの一つにループ状に接続されていて、
前記第1の光ビームスプリッターが前記第2の光ビームスプリッターのポートを介して対象と光学的に結合され、
前記光ビームスプリッターのうちの少なくとも一方が前記光受信器に光学的に結合されていることを特徴とする光学干渉計。 - 該光学干渉計の少なくとも一方の腕が光学遅延線を備えることを特徴とする請求項2に記載の光学干渉計。
- 該光学干渉計の少なくとも一方の腕が位相変調器を備えることを特徴とする請求項2に記載の光学干渉計。
- 前記測定腕の端部に探針が設置されていることを特徴とする請求項2から4のいずれか一項に記載の光学干渉計。
- 前記探針を備えた測定腕の少なくとも一部が光ファイバで作られていることを特徴とする請求項5に記載の光学干渉計。
- 該光学干渉計の少なくとも一方の腕が光ファイバで作られていることを特徴とする請求項2から4のいずれか一項に記載の光学干渉計。
- 前記光ビームスプリッターの少なくとも一方が光ファイバで作られていることを特徴とする請求項2から7のいずれか一項に記載の光学干渉計。
- 前記探針が着脱式に作られていて、該光学干渉計の別の部分とコネクタを使って接続されていることを特徴とする請求項5または6に記載の光学干渉計。
- 前記第1の光ビームスプリッターがノンレシプロカルに作られていることを特徴とする請求項2から9のいずれか一項に記載の光学干渉計。
- 前記第1の光ビームスプリッターが偏光感度性に作られていて、前記測定腕に偏光スイッチが加入されていることを特徴とする請求項2から10のいずれか一項に記載の光学干渉計。
- 光学放射源と、
低干渉性光学放射を第1の低干渉性光学放射のビームおよび第2の低干渉性光学放射のビームに分けるための第1の光ビームスプリッターと、
双方向性の測定腕と、
支持腕であって、低干渉性光学放射が第1及び第2の双方向に該支持腕に沿って伝播するようにループ状に形成された支持腕と、
前記第1の低干渉性光学放射のビームを第3の低干渉性光学放射のビームおよび第4の低干渉性光学放射のビームに分けて、前向きおよび後ろ向きに前記双方向性の測定腕に沿って伝わった前記第3の低干渉性光学放射のビームを、前記第1の方向に前記支持腕のループに沿って伝わった前記第2の低干渉性光学放射のビームと混合することによって第1の混合光学放射を形成するための第2の光ビームスプリッターと、
少なくとも一つの光受信器とを備えた光学干渉計であって、
前記第1の光ビームスプリッターが、前記第2の光ビームスプリッターのポートを介して対象と光学的に結合され、前記第1の光ビームスプリッターが、第1の低干渉性光学放射のビームの一部を、前記第2の方向に前記支持腕のループに沿って伝わった前記第4の低干渉性光学放射のビームと混合することによって、第2の混合光学放射を形成し、
前記光ビームスプリッターのうちの少なくも一方が、前記少なくとも一つの光受信器に接続されている、光学干渉計。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35679802P | 2002-02-14 | 2002-02-14 | |
| PCT/RU2003/000041 WO2003069272A1 (en) | 2002-02-14 | 2003-02-10 | Method for studying an object and an optical interferometer for carrying out said method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005517912A JP2005517912A (ja) | 2005-06-16 |
| JP2005517912A5 JP2005517912A5 (ja) | 2009-08-13 |
| JP4472991B2 true JP4472991B2 (ja) | 2010-06-02 |
Family
ID=27734679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003568347A Expired - Fee Related JP4472991B2 (ja) | 2002-02-14 | 2003-02-10 | 対象の研究方法およびその光学干渉計(変型) |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6992776B2 (ja) |
| EP (1) | EP1475606A4 (ja) |
| JP (1) | JP4472991B2 (ja) |
| CA (1) | CA2474631A1 (ja) |
| RU (1) | RU2240502C1 (ja) |
| WO (1) | WO2003069272A1 (ja) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE454845T1 (de) | 2000-10-30 | 2010-01-15 | Gen Hospital Corp | Optische systeme zur gewebeanalyse |
| US9295391B1 (en) * | 2000-11-10 | 2016-03-29 | The General Hospital Corporation | Spectrally encoded miniature endoscopic imaging probe |
| WO2002088705A2 (en) | 2001-05-01 | 2002-11-07 | The General Hospital Corporation | Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties |
| US7355716B2 (en) | 2002-01-24 | 2008-04-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| JP4472991B2 (ja) | 2002-02-14 | 2010-06-02 | イマラックス・コーポレーション | 対象の研究方法およびその光学干渉計(変型) |
| US7643153B2 (en) | 2003-01-24 | 2010-01-05 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| CA2519937C (en) | 2003-03-31 | 2012-11-20 | Guillermo J. Tearney | Speckle reduction in optical coherence tomography by path length encoded angular compounding |
| ES2310744T3 (es) | 2003-06-06 | 2009-01-16 | The General Hospital Corporation | Fuente de luz sintonizable en longitudes de onda. |
| EP2278287B1 (en) | 2003-10-27 | 2016-09-07 | The General Hospital Corporation | Method and apparatus for performing optical imaging using frequency-domain interferometry |
| FR2870004B1 (fr) * | 2004-05-04 | 2006-07-28 | Thales Sa | Dispositif de mesure a faible cout de decalage en frequence par effet doppler |
| US8018598B2 (en) | 2004-05-29 | 2011-09-13 | The General Hospital Corporation | Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (OCT) imaging |
| AU2005270037B2 (en) | 2004-07-02 | 2012-02-09 | The General Hospital Corporation | Endoscopic imaging probe comprising dual clad fibre |
| JP5053845B2 (ja) | 2004-08-06 | 2012-10-24 | ザ ジェネラル ホスピタル コーポレイション | 光学コヒーレンス断層撮影法を使用して試料中の少なくとも1つの位置を決定するための方法、システムおよびソフトウェア装置 |
| EP1989997A1 (en) | 2004-08-24 | 2008-11-12 | The General Hospital Corporation | Process, System and Software Arrangement for Measuring a Mechanical Strain and Elastic Properties of a Sample |
| JP5324095B2 (ja) | 2004-08-24 | 2013-10-23 | ザ ジェネラル ホスピタル コーポレイション | 血管セグメントを画像化する方法および装置 |
| US7365859B2 (en) | 2004-09-10 | 2008-04-29 | The General Hospital Corporation | System and method for optical coherence imaging |
| EP1804638B1 (en) | 2004-09-29 | 2012-12-19 | The General Hospital Corporation | System and method for optical coherence imaging |
| EP2278266A3 (en) | 2004-11-24 | 2011-06-29 | The General Hospital Corporation | Common-Path Interferometer for Endoscopic OCT |
| WO2006058346A1 (en) | 2004-11-29 | 2006-06-01 | The General Hospital Corporation | Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample |
| EP2325803A1 (en) | 2005-04-28 | 2011-05-25 | The General Hospital Corporation | Evaluating optical coherence tomography information for an anatomical structure |
| EP1887926B1 (en) | 2005-05-31 | 2014-07-30 | The General Hospital Corporation | System and method which use spectral encoding heterodyne interferometry techniques for imaging |
| EP1889037A2 (en) | 2005-06-01 | 2008-02-20 | The General Hospital Corporation | Apparatus, method and system for performing phase-resolved optical frequency domain imaging |
| DE602006017558D1 (de) | 2005-08-09 | 2010-11-25 | Gen Hospital Corp | Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie |
| US7359057B2 (en) * | 2005-08-26 | 2008-04-15 | Ball Aerospace & Technologies Corp. | Method and apparatus for measuring small shifts in optical wavelengths |
| EP1940286A1 (en) | 2005-09-29 | 2008-07-09 | General Hospital Corporation | Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions |
| JP5203951B2 (ja) | 2005-10-14 | 2013-06-05 | ザ ジェネラル ホスピタル コーポレイション | スペクトル及び周波数符号化蛍光画像形成 |
| US7796270B2 (en) | 2006-01-10 | 2010-09-14 | The General Hospital Corporation | Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques |
| CN101384212A (zh) | 2006-01-19 | 2009-03-11 | 通用医疗公司 | 通过上皮内腔器官束扫描对上皮内腔器官进行光学成像的方法和系统 |
| WO2007084903A2 (en) | 2006-01-19 | 2007-07-26 | The General Hospital Corporation | Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements |
| US9186066B2 (en) | 2006-02-01 | 2015-11-17 | The General Hospital Corporation | Apparatus for applying a plurality of electro-magnetic radiations to a sample |
| US10426548B2 (en) | 2006-02-01 | 2019-10-01 | The General Hosppital Corporation | Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures |
| EP3143926B1 (en) | 2006-02-08 | 2020-07-01 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy |
| JP2009527770A (ja) | 2006-02-24 | 2009-07-30 | ザ ジェネラル ホスピタル コーポレイション | 角度分解型のフーリエドメイン光干渉断層撮影法を遂行する方法及びシステム |
| US7742173B2 (en) * | 2006-04-05 | 2010-06-22 | The General Hospital Corporation | Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample |
| EP3150110B1 (en) | 2006-05-10 | 2020-09-02 | The General Hospital Corporation | Processes, arrangements and systems for providing frequency domain imaging of a sample |
| US7782464B2 (en) | 2006-05-12 | 2010-08-24 | The General Hospital Corporation | Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images |
| US20070291277A1 (en) | 2006-06-20 | 2007-12-20 | Everett Matthew J | Spectral domain optical coherence tomography system |
| EP2054712B1 (en) | 2006-08-25 | 2015-10-07 | The General Hospital Corporation | Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques |
| WO2008049118A2 (en) * | 2006-10-19 | 2008-04-24 | The General Hospital Corporation | Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s) |
| WO2008089406A2 (en) | 2007-01-19 | 2008-07-24 | The General Hospital Corporation | Apparatus and method for simultaneous inspection at different depths based on the principle of frequency domain optical coherence tomography |
| WO2008089342A1 (en) | 2007-01-19 | 2008-07-24 | The General Hospital Corporation | Rotating disk reflection for fast wavelength scanning of dispersed broadband light |
| US7916985B2 (en) * | 2007-02-19 | 2011-03-29 | Kla-Tencor Corporation | Integrated visible pilot beam for non-visible optical waveguide devices |
| EP2602651A3 (en) | 2007-03-23 | 2014-08-27 | The General Hospital Corporation | Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures |
| US10534129B2 (en) | 2007-03-30 | 2020-01-14 | The General Hospital Corporation | System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque |
| US8045177B2 (en) | 2007-04-17 | 2011-10-25 | The General Hospital Corporation | Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy |
| WO2009018456A2 (en) | 2007-07-31 | 2009-02-05 | The General Hospital Corporation | Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging |
| EP2191254B1 (en) | 2007-08-31 | 2017-07-19 | The General Hospital Corporation | System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith |
| WO2009059034A1 (en) | 2007-10-30 | 2009-05-07 | The General Hospital Corporation | System and method for cladding mode detection |
| US7573020B1 (en) * | 2008-01-17 | 2009-08-11 | Imalux Corporation | Optoelectronic probe system with all-optical coupling |
| US7898656B2 (en) * | 2008-04-30 | 2011-03-01 | The General Hospital Corporation | Apparatus and method for cross axis parallel spectroscopy |
| US8593619B2 (en) | 2008-05-07 | 2013-11-26 | The General Hospital Corporation | System, method and computer-accessible medium for tracking vessel motion during three-dimensional coronary artery microscopy |
| JP5795531B2 (ja) | 2008-06-20 | 2015-10-14 | ザ ジェネラル ホスピタル コーポレイション | フューズドファイバオプティックカプラ構造、及びその使用方法 |
| US20100004531A1 (en) * | 2008-07-07 | 2010-01-07 | Passmore Charles G | Measurement catheter |
| WO2010009136A2 (en) | 2008-07-14 | 2010-01-21 | The General Hospital Corporation | Apparatus and methods for color endoscopy |
| EP2359121A4 (en) | 2008-12-10 | 2013-08-14 | Gen Hospital Corp | SYSTEMS, DEVICE AND METHOD FOR EXPANDING THE IMAGING DEPTH RANGE IN OPTICAL COHERENCE TOMOPOMAGRAPH BY OPTICAL SUB-TESTING |
| US20100238452A1 (en) * | 2008-12-15 | 2010-09-23 | Frederique Vanholsbeeck | Dual Fiber Stretchers for Dispersion Compensation |
| WO2010090837A2 (en) | 2009-01-20 | 2010-08-12 | The General Hospital Corporation | Endoscopic biopsy apparatus, system and method |
| JP2012515930A (ja) | 2009-01-26 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレーション | 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体 |
| US9178330B2 (en) | 2009-02-04 | 2015-11-03 | The General Hospital Corporation | Apparatus and method for utilization of a high-speed optical wavelength tuning source |
| US9351642B2 (en) | 2009-03-12 | 2016-05-31 | The General Hospital Corporation | Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s) |
| BR112012001042A2 (pt) | 2009-07-14 | 2016-11-22 | Gen Hospital Corp | equipamento e método de medição do fluxo de fluído dentro de estrutura anatômica. |
| EP2542145B1 (en) | 2010-03-05 | 2020-08-12 | The General Hospital Corporation | Systems which provide microscopic images of at least one anatomical structure at a particular resolution |
| US9069130B2 (en) | 2010-05-03 | 2015-06-30 | The General Hospital Corporation | Apparatus, method and system for generating optical radiation from biological gain media |
| US9795301B2 (en) | 2010-05-25 | 2017-10-24 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images |
| EP2575597B1 (en) | 2010-05-25 | 2022-05-04 | The General Hospital Corporation | Apparatus for providing optical imaging of structures and compositions |
| WO2011153434A2 (en) | 2010-06-03 | 2011-12-08 | The General Hospital Corporation | Apparatus and method for devices for imaging structures in or at one or more luminal organs |
| EP2598855B1 (en) | 2010-08-19 | 2016-03-23 | Halliburton Energy Services, Inc. | Optical pressure sensor |
| JP5883018B2 (ja) | 2010-10-27 | 2016-03-09 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも1つの血管内部の血圧を測定するための装置、システム、および方法 |
| WO2013013049A1 (en) | 2011-07-19 | 2013-01-24 | The General Hospital Corporation | Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography |
| EP2748587B1 (en) | 2011-08-25 | 2021-01-13 | The General Hospital Corporation | Methods and arrangements for providing micro-optical coherence tomography procedures |
| US9341783B2 (en) | 2011-10-18 | 2016-05-17 | The General Hospital Corporation | Apparatus and methods for producing and/or providing recirculating optical delay(s) |
| US9629528B2 (en) | 2012-03-30 | 2017-04-25 | The General Hospital Corporation | Imaging system, method and distal attachment for multidirectional field of view endoscopy |
| EP2852315A4 (en) | 2012-05-21 | 2016-06-08 | Gen Hospital Corp | DEVICE, APPARATUS AND METHOD FOR CAPSULE MICROSCOPY |
| DE102012211549B3 (de) * | 2012-07-03 | 2013-07-04 | Polytec Gmbh | Vorrichtung und Verfahren zur interferometrischen Vermessung eines Objekts |
| JP6227652B2 (ja) | 2012-08-22 | 2017-11-08 | ザ ジェネラル ホスピタル コーポレイション | ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体 |
| US9968261B2 (en) | 2013-01-28 | 2018-05-15 | The General Hospital Corporation | Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging |
| US10893806B2 (en) | 2013-01-29 | 2021-01-19 | The General Hospital Corporation | Apparatus, systems and methods for providing information regarding the aortic valve |
| WO2014121082A1 (en) | 2013-02-01 | 2014-08-07 | The General Hospital Corporation | Objective lens arrangement for confocal endomicroscopy |
| WO2014144709A2 (en) | 2013-03-15 | 2014-09-18 | The General Hospital Corporation | Methods and systems for characterizing an object |
| EP2997354A4 (en) | 2013-05-13 | 2017-01-18 | The General Hospital Corporation | Detecting self-interefering fluorescence phase and amplitude |
| EP2813801B1 (en) * | 2013-06-10 | 2018-10-31 | Mitutoyo Corporation | Interferometer system and method to generate an interference signal of a surface of a sample |
| WO2015009932A1 (en) | 2013-07-19 | 2015-01-22 | The General Hospital Corporation | Imaging apparatus and method which utilizes multidirectional field of view endoscopy |
| EP3021735A4 (en) | 2013-07-19 | 2017-04-19 | The General Hospital Corporation | Determining eye motion by imaging retina. with feedback |
| WO2015013651A2 (en) | 2013-07-26 | 2015-01-29 | The General Hospital Corporation | System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography |
| RU2547346C1 (ru) * | 2013-10-30 | 2015-04-10 | Федеральное государственное бюджетное учреждение науки Институт физики микроструктур Российской академии наук (ИФМ РАН) | Низкокогерентный интерферометр с дифракционной волной сравнения и источник двух сферических эталонных волн для него |
| WO2015105870A1 (en) | 2014-01-08 | 2015-07-16 | The General Hospital Corporation | Method and apparatus for microscopic imaging |
| US10736494B2 (en) | 2014-01-31 | 2020-08-11 | The General Hospital Corporation | System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device |
| JP6446803B2 (ja) * | 2014-03-25 | 2019-01-09 | 日本電気株式会社 | 光送受信器 |
| US10228556B2 (en) | 2014-04-04 | 2019-03-12 | The General Hospital Corporation | Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s) |
| JP2017525435A (ja) | 2014-07-25 | 2017-09-07 | ザ ジェネラル ホスピタル コーポレイション | インビボ・イメージングおよび診断のための機器、デバイスならびに方法 |
| JP6667894B2 (ja) * | 2015-10-21 | 2020-03-18 | 国立大学法人 奈良先端科学技術大学院大学 | 検出装置、検出方法 |
| US11262191B1 (en) * | 2018-07-12 | 2022-03-01 | Onto Innovation Inc. | On-axis dynamic interferometer and optical imaging systems employing the same |
| RU2714865C1 (ru) * | 2019-06-18 | 2020-02-19 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр Институт прикладной физики Российской академии наук" (ИПФ РАН) | Интерферометр |
| DE102020114610A1 (de) | 2020-06-02 | 2021-12-02 | Heidelberg Engineering Gmbh | Anordnung zur Durchführung einer optischen Kohärenztomografie |
| DE102021118555A1 (de) | 2021-07-19 | 2023-01-19 | Heidelberg Engineering Gmbh | Interferometer zur Durchführung einer optischen Kohärenztomografie |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5321501A (en) * | 1991-04-29 | 1994-06-14 | Massachusetts Institute Of Technology | Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample |
| US5291267A (en) * | 1992-01-22 | 1994-03-01 | Hewlett-Packard Company | Optical low-coherence reflectometry using optical amplification |
| US5268738A (en) * | 1992-06-30 | 1993-12-07 | Hewlett-Packard Company | Extended distance range optical low-coherence reflectometer |
| RU2100787C1 (ru) * | 1995-03-01 | 1997-12-27 | Геликонов Валентин Михайлович | Оптоволоконный интерферометр и оптоволоконный пьезоэлектрический преобразователь |
| US6201608B1 (en) * | 1998-03-13 | 2001-03-13 | Optical Biopsy Technologies, Inc. | Method and apparatus for measuring optical reflectivity and imaging through a scattering medium |
| US5975697A (en) * | 1998-11-25 | 1999-11-02 | Oti Ophthalmic Technologies, Inc. | Optical mapping apparatus with adjustable depth resolution |
| RU2169347C1 (ru) * | 1999-11-29 | 2001-06-20 | Геликонов Валентин Михайлович | Оптический интерферометр (варианты) |
| JP2003516531A (ja) * | 1999-12-09 | 2003-05-13 | オーティーアイ オフサルミック テクノロジーズ インク | 可変奥行き解像力を有する光学マッピング装置 |
| EP1149556B1 (en) * | 2000-04-26 | 2007-08-15 | FUJIFILM Corporation | Optical tomograph |
| JP4472991B2 (ja) | 2002-02-14 | 2010-06-02 | イマラックス・コーポレーション | 対象の研究方法およびその光学干渉計(変型) |
-
2003
- 2003-02-10 JP JP2003568347A patent/JP4472991B2/ja not_active Expired - Fee Related
- 2003-02-10 RU RU2003103627/28A patent/RU2240502C1/ru not_active IP Right Cessation
- 2003-02-10 CA CA002474631A patent/CA2474631A1/en not_active Abandoned
- 2003-02-10 WO PCT/RU2003/000041 patent/WO2003069272A1/ru not_active Ceased
- 2003-02-10 EP EP03710558A patent/EP1475606A4/en not_active Withdrawn
- 2003-02-14 US US10/367,396 patent/US6992776B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005517912A (ja) | 2005-06-16 |
| EP1475606A4 (en) | 2007-04-04 |
| US6992776B2 (en) | 2006-01-31 |
| US20030174339A1 (en) | 2003-09-18 |
| WO2003069272A1 (en) | 2003-08-21 |
| CA2474631A1 (en) | 2003-08-21 |
| EP1475606A1 (en) | 2004-11-10 |
| RU2240502C1 (ru) | 2004-11-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4472991B2 (ja) | 対象の研究方法およびその光学干渉計(変型) | |
| JP2005517912A5 (ja) | ||
| CA2908992C (en) | PHOTOACOUSTIC REMOTE SENSING (PARS) | |
| US7474407B2 (en) | Optical coherence tomography with 3d coherence scanning | |
| JP4555074B2 (ja) | 対象をイメージングするための装置及び低干渉性光学放射を届けるための装置 | |
| US7705992B2 (en) | Optical coherence tomography system | |
| US6665456B2 (en) | Method and apparatus for differential phase optical coherence tomography | |
| US6853457B2 (en) | Optical amplification in coherence reflectometry | |
| KR101384553B1 (ko) | 주파수 영역 간섭법을 이용하여 광 영상화를 수행하는 방법 및 장치 | |
| US6900943B2 (en) | Optical amplification in coherent optical frequency modulated continuous wave reflectometry | |
| US20090073444A1 (en) | Optical measurements of properties in substances using propagation modes of light | |
| JP2005529322A5 (ja) | ||
| WO1999046557A1 (en) | Method and apparatus for measuring optical reflectivity and imaging through a scattering medium | |
| US20080252900A1 (en) | Optical tomography system | |
| CN101297750A (zh) | 一种复谱频域光学相干层析成像方法以及系统 | |
| US10591275B2 (en) | Polarization sensitive optical coherence tomography using multiple polarization sensitive semiconductor optical amplifiers | |
| EP1253398A1 (en) | Optical interferometer (variants) | |
| US12298133B2 (en) | High-resolution handheld OCT imaging system | |
| Gelikonov | Methods of cross polarization OCT | |
| Gelikonov | Features of cross-polarization imaging | |
| Yu et al. | Instrumentation of fiber-based functional optical coherence tomographic imaging system | |
| Jiang et al. | Formulation of beam propagating through the organized tissues withpolarization-sensitive OCT | |
| Milner et al. | Method and apparatus for differential phase optical coherence tomography | |
| Sharma | Fiber lasers and all-fiber optic devices for applications in sensing and medical imaging |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060126 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20081202 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090302 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090309 |
|
| A524 | Written submission of copy of amendment under article 19 pct |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20090602 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20091218 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091225 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100202 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20100304 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130312 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140312 Year of fee payment: 4 |
|
| LAPS | Cancellation because of no payment of annual fees |