JP4944611B2 - ニューロンの成長を調節する化合物およびそれらの使用 - Google Patents

ニューロンの成長を調節する化合物およびそれらの使用 Download PDF

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JP4944611B2
JP4944611B2 JP2006526381A JP2006526381A JP4944611B2 JP 4944611 B2 JP4944611 B2 JP 4944611B2 JP 2006526381 A JP2006526381 A JP 2006526381A JP 2006526381 A JP2006526381 A JP 2006526381A JP 4944611 B2 JP4944611 B2 JP 4944611B2
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cyclic peptide
trk
peptide
receptor
amino acid
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Japanese (ja)
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JP2007505145A (ja
JP2007505145A5 (2
Inventor
パトリック・ドハーティ
ギャレス・ウィリアムズ
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キングズ カレッジ ロンドン
ワイス・エルエルシー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2006526381A 2003-09-10 2004-09-10 ニューロンの成長を調節する化合物およびそれらの使用 Expired - Fee Related JP4944611B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US50186403P 2003-09-10 2003-09-10
US60/501,864 2003-09-10
US55989804P 2004-04-05 2004-04-05
US60/559,898 2004-04-05
US60318704P 2004-08-20 2004-08-20
US60/603,187 2004-08-20
PCT/US2004/029888 WO2005025514A2 (en) 2003-09-10 2004-09-10 Compounds that modulate neuronal growth and their uses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010235591A Division JP2011057685A (ja) 2003-09-10 2010-10-20 ニューロンの成長を調節する化合物およびそれらの使用

Publications (3)

Publication Number Publication Date
JP2007505145A JP2007505145A (ja) 2007-03-08
JP2007505145A5 JP2007505145A5 (2) 2007-06-07
JP4944611B2 true JP4944611B2 (ja) 2012-06-06

Family

ID=34317473

Family Applications (2)

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JP2006526381A Expired - Fee Related JP4944611B2 (ja) 2003-09-10 2004-09-10 ニューロンの成長を調節する化合物およびそれらの使用
JP2010235591A Pending JP2011057685A (ja) 2003-09-10 2010-10-20 ニューロンの成長を調節する化合物およびそれらの使用

Family Applications After (1)

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JP2010235591A Pending JP2011057685A (ja) 2003-09-10 2010-10-20 ニューロンの成長を調節する化合物およびそれらの使用

Country Status (7)

Country Link
US (1) US7196061B2 (2)
EP (2) EP2438925A3 (2)
JP (2) JP4944611B2 (2)
AU (1) AU2004272107B2 (2)
BR (1) BRPI0414323A (2)
CA (1) CA2535279A1 (2)
WO (1) WO2005025514A2 (2)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005004343A1 (de) * 2005-01-25 2006-08-10 Eberhard-Karls-Universität Tübingen Universitätsklinikum Behandlung von Phantomphänomenen
WO2006130781A2 (en) * 2005-06-01 2006-12-07 The Scripps Research Institute Crystal of a cytochrome-ligand complex and methods of use
US8195021B2 (en) 2006-11-03 2012-06-05 Tufts University/Trustees Of Tufts College Biopolymer optical waveguide and method of manufacturing the same
US8529835B2 (en) * 2006-11-03 2013-09-10 Tufts University Biopolymer sensor and method of manufacturing the same
JP2010509645A (ja) 2006-11-03 2010-03-25 トラスティーズ オブ タフツ カレッジ ナノパターンが形成されたバイオポリマー光学デバイスおよびその製造方法
JP2011231085A (ja) * 2010-04-30 2011-11-17 Osaka Prefecture Univ 環状ペプチド
WO2016146730A1 (en) * 2015-03-19 2016-09-22 Neuheart S.R.L. PEPTIDES HAVING TrkA-RECEPTOR-AGONISTIC ACTIVITY OR HAVING NGF-ANTAGONISTIC ACTIVITY
CN113993880A (zh) * 2019-06-11 2022-01-28 富士胶片株式会社 环肽、细胞支架材料、细胞分离材料及培养基
WO2021256619A1 (ko) * 2020-06-18 2021-12-23 연세대학교 산학협력단 시냅스 가소성 조절 기능의 펩타이드를 포함하는 인지기능 장애 질환의 예방, 개선 또는 치료용 조성물
US20230312651A1 (en) * 2020-07-10 2023-10-05 The University Of Tokyo Cyclic Peptide, Peptide Complex, and Drug Composition Containing Said Cyclic Peptide and/or Said Peptide Complex

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079600A (en) 1987-03-06 1992-01-07 Schnur Joel M High resolution patterning on solid substrates
US5245012A (en) 1990-04-19 1993-09-14 The United States Of America As Represented By The Secretary Of The Army Method to achieve solubilization of spider silk proteins
US5364769A (en) 1990-09-25 1994-11-15 Genentech, Inc. Nucleic acid encoding neurotrophic factor four (NT-4), vectors, host cells and methods of production
US5981478A (en) * 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
GB9402331D0 (en) 1994-02-07 1994-03-30 Univ Mcgill Nerve growth factor structural analogs and their uses
US5844092A (en) 1994-03-18 1998-12-01 Genentech, Inc. Human TRK receptors and neurotrophic factor inhibitors
US5877016A (en) 1994-03-18 1999-03-02 Genentech, Inc. Human trk receptors and neurotrophic factor inhibitors
US5660848A (en) 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
CA2256543C (en) * 1996-05-31 2010-12-07 The Scripps Research Institute Methods and compositions useful for inhibition of angiogenesis
US20020168761A1 (en) 2000-01-24 2002-11-14 Gour Barbara J. Peptidomimetic modulators of cell adhesion
US6031072A (en) 1996-07-12 2000-02-29 Mcgill University Compounds and methods for modulating cell adhesion
US6096707A (en) * 1997-07-11 2000-08-01 Biotie Therapies Ltd. Integrin binding peptide and use thereof
HU229520B1 (en) * 1999-02-12 2014-01-28 Scripps Research Inst Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
AU2001273245A1 (en) * 2000-07-05 2002-01-14 Pangene Corporation Modulators of trk protein activity, compositions and uses

Also Published As

Publication number Publication date
JP2011057685A (ja) 2011-03-24
WO2005025514A2 (en) 2005-03-24
AU2004272107B2 (en) 2011-04-07
EP1663276A2 (en) 2006-06-07
CA2535279A1 (en) 2005-03-24
US7196061B2 (en) 2007-03-27
EP1663276A4 (en) 2009-02-18
WO2005025514A3 (en) 2005-08-11
AU2004272107A1 (en) 2005-03-24
JP2007505145A (ja) 2007-03-08
BRPI0414323A (pt) 2006-11-07
US20050164920A1 (en) 2005-07-28
EP2438925A3 (en) 2012-08-29
EP2438925A2 (en) 2012-04-11

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