JP5468978B2 - Rna干渉において使用するための修飾ポリヌクレオチド - Google Patents

Rna干渉において使用するための修飾ポリヌクレオチド Download PDF

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Publication number
JP5468978B2
JP5468978B2 JP2010106021A JP2010106021A JP5468978B2 JP 5468978 B2 JP5468978 B2 JP 5468978B2 JP 2010106021 A JP2010106021 A JP 2010106021A JP 2010106021 A JP2010106021 A JP 2010106021A JP 5468978 B2 JP5468978 B2 JP 5468978B2
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Prior art keywords
nucleotide
sense
sirna
modification
antisense
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Japanese (ja)
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JP2010172344A (ja
Inventor
リーク デビン
レイノルズ アンジェラ
フボロバ アンジェラ
マーシャル ウィリアム
フェデロブ ユリー
ニコルス キンバーリー
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サーモ フィッシャー サイエンティフィック バイオサイエンシィズ インク.
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Priority claimed from US10/406,908 external-priority patent/US20040198640A1/en
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JP2010106021A 2003-04-02 2010-04-30 Rna干渉において使用するための修飾ポリヌクレオチド Expired - Lifetime JP5468978B2 (ja)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US10/406,908 US20040198640A1 (en) 2003-04-02 2003-04-02 Stabilized polynucleotides for use in RNA interference
US10/406,908 2003-04-02
US10/613,077 US20040266707A1 (en) 2003-04-02 2003-07-01 Stabilized polynucleotides for use in RNA interference
US10/613,077 2003-07-01
US54264604P 2004-02-06 2004-02-06
US54266804P 2004-02-06 2004-02-06
US60/542,668 2004-02-06
US60/542,646 2004-02-06
US54366104P 2004-02-10 2004-02-10
US54364004P 2004-02-10 2004-02-10
US60/543,661 2004-02-10
US60/543,640 2004-02-10

Related Parent Applications (1)

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JP2006509678A Division JP4605799B2 (ja) 2003-04-02 2004-04-01 Rna干渉において使用するための修飾ポリヌクレオチド

Publications (2)

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JP2010172344A JP2010172344A (ja) 2010-08-12
JP5468978B2 true JP5468978B2 (ja) 2014-04-09

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JP2010106021A Expired - Lifetime JP5468978B2 (ja) 2003-04-02 2010-04-30 Rna干渉において使用するための修飾ポリヌクレオチド

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JP (1) JP5468978B2 (de)
AT (1) ATE536408T1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR083445A1 (es) 2010-10-14 2013-02-27 Univ Mie siARN CONTRA LA FIBROSIS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2429814C (en) * 2000-12-01 2014-02-18 Thomas Tuschl Rna interference mediating small rna molecules
WO2003012052A2 (en) * 2001-07-30 2003-02-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Specific inhibition of gene expression by small double stranded rnas
DE60310944T3 (de) * 2002-08-05 2017-08-03 Silence Therapeutics Gmbh Weitere neue formen von interferierende rns moleküle

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Publication number Publication date
ATE536408T1 (de) 2011-12-15
JP2010172344A (ja) 2010-08-12

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