JP6531990B2 - 心肺血行動態を改善するための無機亜硝酸塩 - Google Patents

心肺血行動態を改善するための無機亜硝酸塩 Download PDF

Info

Publication number: JP6531990B2
Authority: JP; Japan
Prior art keywords: nitrite; administered; pulmonary; inorganic nitrite; agent according
Prior art date: 2013-02-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

JP2015560384A

Other languages

English (en)

Japanese (ja)

Other versions

JP2016510040A (ja

JP2016510040A5 (2

Inventor

トーマスグラッドウィン，マーク

クレイチャンピオン，ハンター

パセリ，エドウィン

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Pittsburgh

Original Assignee

University of Pittsburgh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-02-28

Filing date

2014-02-28

Publication date

2019-06-19

2014-02-28 Application filed by University of Pittsburgh filed Critical University of Pittsburgh

2016-04-04 Publication of JP2016510040A publication Critical patent/JP2016510040A/ja

2017-03-30 Publication of JP2016510040A5 publication Critical patent/JP2016510040A5/ja

2019-06-19 Application granted granted Critical

2019-06-19 Publication of JP6531990B2 publication Critical patent/JP6531990B2/ja

Status Active legal-status Critical Current

2034-02-28 Anticipated expiration legal-status Critical

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Inorganic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Otolaryngology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

JP2015560384A 2013-02-28 2014-02-28 心肺血行動態を改善するための無機亜硝酸塩 Active JP6531990B2 (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201361771063P	2013-02-28	2013-02-28
US61/771,063		2013-02-28
PCT/US2014/019703 WO2014134585A1 (en)	2013-02-28	2014-02-28	Inorganic nitrite to improve cardiopulmonary hemodynamics

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2019088704A Division JP2019123754A (ja)	2013-02-28	2019-05-09	心肺血行動態を改善するための無機亜硝酸塩

Publications (3)

Publication Number	Publication Date
JP2016510040A JP2016510040A (ja)	2016-04-04
JP2016510040A5 JP2016510040A5 (2)	2017-03-30
JP6531990B2 true JP6531990B2 (ja)	2019-06-19

Family

ID=51428880

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
JP2015560384A Active JP6531990B2 (ja)	2013-02-28	2014-02-28	心肺血行動態を改善するための無機亜硝酸塩
JP2019088704A Pending JP2019123754A (ja)	2013-02-28	2019-05-09	心肺血行動態を改善するための無機亜硝酸塩
JP2022103254A Pending JP2022121544A (ja)	2013-02-28	2022-06-28	心肺血行動態を改善するための無機亜硝酸塩

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
JP2019088704A Pending JP2019123754A (ja)	2013-02-28	2019-05-09	心肺血行動態を改善するための無機亜硝酸塩
JP2022103254A Pending JP2022121544A (ja)	2013-02-28	2022-06-28	心肺血行動態を改善するための無機亜硝酸塩

Country Status (5)

Country	Link
US (3)	US20160008394A1 (2)
EP (1)	EP2961479A4 (2)
JP (3)	JP6531990B2 (2)
CA (1)	CA2902965C (2)
WO (1)	WO2014134585A1 (2)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2294543T3 (es)	2003-07-09	2008-04-01	The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal	Uso de sales de nitrilo para el tratamiento de afecciones cardiovasculares.
EP2953631A4 (en) *	2013-02-07	2017-03-01	The Trustees Of The University Of Pennsylvania	Methods of treating heart failure
US20160008394A1 (en) *	2013-02-28	2016-01-14	Aires Pharmaceuticals, Inc.	Inorganic nitrite to improve cardiopulmonary hemodynamics
US11083704B2 (en) *	2017-01-03	2021-08-10	Bristol-Myers Squibb Company	Method of administering nitroxyl donating compounds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4509515A (en)	1982-02-23	1985-04-09	Fisons Plc	Inhalation device
US4889116A (en)	1987-11-17	1989-12-26	Phospho Energetics, Inc.	Adaptive control of neonatal fractional inspired oxygen
WO1992010228A1 (en)	1990-12-05	1992-06-25	The General Hospital Corporation	Devices for treating pulmonary vasoconstriction and asthma
US5427797A (en)	1993-04-06	1995-06-27	Brigham And Women's Hospital	Systemic effects of nitric oxide inhalation
AU5939901A (en) *	2000-10-27	2002-05-06	Nitromed Inc	Methods of treating vascular diseases characterized by nitric oxide insufficiency
ES2294543T3 (es) *	2003-07-09	2008-04-01	The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal	Uso de sales de nitrilo para el tratamiento de afecciones cardiovasculares.
DK2124638T3 (en)	2007-02-26	2017-03-20	Heartbeet Ltd	COMPOSITION INCREASING PERFORMANCE AND USING IT
CA2678097C (en)	2007-02-26	2023-03-14	Jon Lundberg	New use of nitrites and nitrates and compositions containing these
WO2009029836A2 (en) *	2007-08-31	2009-03-05	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Nitrite and nitrite-metheme therapy to detoxify stroma-free hemoglobin based blood substitutes
US20120208762A1 (en)	2009-10-27	2012-08-16	The Board Of Trustees Of The University Of Illinois	Methods of Diagnosing Diastolic Dysfunction
GB201020811D0 (en) *	2010-12-08	2011-01-19	Solvotrin Innovations Ltd	Compounds
US20140112983A1 (en) *	2011-04-14	2014-04-24	Theravasc Inc.	Nitrite compositions and uses thereof
WO2013116194A2 (en) *	2012-01-30	2013-08-08	O'connell Timothy D	Method of treating or limiting development of heart failure with preserved ejection fraction and tissue fibrosis
EP2953631A4 (en) *	2013-02-07	2017-03-01	The Trustees Of The University Of Pennsylvania	Methods of treating heart failure
US20160008394A1 (en) *	2013-02-28	2016-01-14	Aires Pharmaceuticals, Inc.	Inorganic nitrite to improve cardiopulmonary hemodynamics

2014
- 2014-02-28 US US14/768,198 patent/US20160008394A1/en not_active Abandoned
- 2014-02-28 EP EP14757027.9A patent/EP2961479A4/en not_active Ceased
- 2014-02-28 CA CA2902965A patent/CA2902965C/en active Active
- 2014-02-28 JP JP2015560384A patent/JP6531990B2/ja active Active
- 2014-02-28 WO PCT/US2014/019703 patent/WO2014134585A1/en not_active Ceased
2018
- 2018-04-16 US US15/954,304 patent/US11219640B2/en active Active
2019
- 2019-05-09 JP JP2019088704A patent/JP2019123754A/ja active Pending
2021
- 2021-12-02 US US17/540,965 patent/US11986493B2/en active Active
2022
- 2022-06-28 JP JP2022103254A patent/JP2022121544A/ja active Pending

Also Published As

Publication number	Publication date
CA2902965C (en)	2023-08-29
US11986493B2 (en)	2024-05-21
US20160008394A1 (en)	2016-01-14
US11219640B2 (en)	2022-01-11
WO2014134585A1 (en)	2014-09-04
US20180360873A1 (en)	2018-12-20
JP2016510040A (ja)	2016-04-04
EP2961479A4 (en)	2017-07-05
JP2019123754A (ja)	2019-07-25
EP2961479A1 (en)	2016-01-06
JP2022121544A (ja)	2022-08-19
US20220088065A1 (en)	2022-03-24
CA2902965A1 (en)	2014-09-04

Legal Events

Date	Code	Title	Description
2017-02-27	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170227
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2018-07-31	A131	Notification of reasons for refusal	Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180731
2019-03-27	TRDD	Decision of grant or rejection written
2019-04-09	A01	Written decision to grant a patent or to grant a registration (utility model)	Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190409
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