JP6604963B2 - 鼻涙腺刺激のためのポリマー配合物 - Google Patents
鼻涙腺刺激のためのポリマー配合物 Download PDFInfo
- Publication number
- JP6604963B2 JP6604963B2 JP2016553890A JP2016553890A JP6604963B2 JP 6604963 B2 JP6604963 B2 JP 6604963B2 JP 2016553890 A JP2016553890 A JP 2016553890A JP 2016553890 A JP2016553890 A JP 2016553890A JP 6604963 B2 JP6604963 B2 JP 6604963B2
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- JP
- Japan
- Prior art keywords
- hydrogel
- formulation
- monomer
- hydration
- tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0546—Nasal electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/52—Amides or imides
- C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01B—CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
- H01B1/00—Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors
- H01B1/06—Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of other non-metallic substances
- H01B1/12—Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of other non-metallic substances organic substances
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01B—CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
- H01B1/00—Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors
- H01B1/06—Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of other non-metallic substances
- H01B1/12—Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of other non-metallic substances organic substances
- H01B1/124—Intrinsically conductive polymers
- H01B1/125—Intrinsically conductive polymers comprising aliphatic main chains, e.g. polyactylenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0492—Patch electrodes
- A61N1/0496—Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
- Y10T29/49885—Assembling or joining with coating before or during assembling
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
- Electrotherapy Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Neurology (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Neurosurgery (AREA)
- Polymerisation Methods In General (AREA)
- Materials For Medical Uses (AREA)
- Manufacturing & Machinery (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461944340P | 2014-02-25 | 2014-02-25 | |
| US61/944,340 | 2014-02-25 | ||
| US201462027139P | 2014-07-21 | 2014-07-21 | |
| US62/027,139 | 2014-07-21 | ||
| US201462035221P | 2014-08-08 | 2014-08-08 | |
| US62/035,221 | 2014-08-08 | ||
| US201462067350P | 2014-10-22 | 2014-10-22 | |
| US62/067,350 | 2014-10-22 | ||
| PCT/US2015/017379 WO2015130707A2 (en) | 2014-02-25 | 2015-02-24 | Polymer formulations for nasolacrimal stimulation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019188335A Division JP2020022785A (ja) | 2014-02-25 | 2019-10-15 | 鼻涙腺刺激のためのポリマー配合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017509747A JP2017509747A (ja) | 2017-04-06 |
| JP2017509747A5 JP2017509747A5 (2) | 2018-04-05 |
| JP6604963B2 true JP6604963B2 (ja) | 2019-11-20 |
Family
ID=53881227
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553890A Expired - Fee Related JP6604963B2 (ja) | 2014-02-25 | 2015-02-24 | 鼻涙腺刺激のためのポリマー配合物 |
| JP2019188335A Ceased JP2020022785A (ja) | 2014-02-25 | 2019-10-15 | 鼻涙腺刺激のためのポリマー配合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019188335A Ceased JP2020022785A (ja) | 2014-02-25 | 2019-10-15 | 鼻涙腺刺激のためのポリマー配合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9770583B2 (2) |
| EP (2) | EP3110405B1 (2) |
| JP (2) | JP6604963B2 (2) |
| CN (2) | CN106470673B (2) |
| AU (1) | AU2015223184B2 (2) |
| CA (1) | CA2940533A1 (2) |
| ES (1) | ES2812752T3 (2) |
| MX (2) | MX2016011118A (2) |
| RU (1) | RU2698711C2 (2) |
| SA (1) | SA516371733B1 (2) |
| WO (1) | WO2015130707A2 (2) |
| ZA (1) | ZA201605563B (2) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
| US20140228875A1 (en) | 2013-02-08 | 2014-08-14 | Nidus Medical, Llc | Surgical device with integrated visualization and cauterization |
| EP2967817B1 (en) | 2013-03-12 | 2021-03-10 | Oculeve, Inc. | Implant delivery devices and systems |
| NZ704579A (en) | 2013-04-19 | 2018-10-26 | Oculeve Inc | Nasal stimulation devices and methods |
| US20150031946A1 (en) | 2013-07-24 | 2015-01-29 | Nidus Medical, Llc | Direct vision cryosurgical probe and methods of use |
| WO2015048806A2 (en) | 2013-09-30 | 2015-04-02 | Nidus Medical, Llc | Apparatus and methods for treating rhinitis |
| WO2015130707A2 (en) | 2014-02-25 | 2015-09-03 | Oculeve, Inc. | Polymer formulations for nasolacrimal stimulation |
| CA2956176A1 (en) | 2014-07-25 | 2016-01-28 | Oculeve, Inc. | Stimulation patterns for treating dry eye |
| US9763743B2 (en) | 2014-07-25 | 2017-09-19 | Arrinex, Inc. | Apparatus and method for treating rhinitis |
| EP3209370A4 (en) | 2014-10-22 | 2018-05-30 | Oculeve, Inc. | Contact lens for increasing tear production |
| RU2707167C2 (ru) | 2014-10-22 | 2019-11-22 | Окулив, Инк. | Устройства для стимуляции и способы лечения болезни "сухого глаза" |
| WO2016065213A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Implantable nasal stimulator systems and methods |
| US10743838B2 (en) | 2015-02-25 | 2020-08-18 | Decision Sciences Medical Company, LLC | Acoustic signal transmission couplants and coupling mediums |
| WO2016205107A1 (en) | 2015-06-16 | 2016-12-22 | The Regents Of The University Of Colorado, A Body Corporate | Nasolacrimal implants and related methods for tear stimulation |
| WO2017062690A1 (en) * | 2015-10-06 | 2017-04-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Moisture permeable hydrogel composite materials |
| US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
| EP3413822B1 (en) | 2016-02-11 | 2023-08-30 | Arrinex, Inc. | Device for image guided post-nasal nerve ablation |
| US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
| CA3022683A1 (en) * | 2016-05-02 | 2017-11-09 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
| EP3471638B1 (en) | 2016-06-15 | 2025-01-29 | Arrinex, Inc. | Devices for treating a lateral surface of a nasal cavity |
| US12233017B2 (en) | 2016-10-14 | 2025-02-25 | Olympic Ophthalmics, Inc. | Quiet handheld devices and methods for treatment of disorders |
| US11253312B2 (en) | 2016-10-17 | 2022-02-22 | Arrinex, Inc. | Integrated nasal nerve detector ablation-apparatus, nasal nerve locator, and methods of use |
| KR20190124698A (ko) | 2016-12-02 | 2019-11-05 | 오큘레브, 인크. | 건성안 예측 및 치료 권고를 위한 장치 및 방법 |
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| WO2018201158A1 (en) | 2017-04-28 | 2018-11-01 | Arrinx, Inc. | Systems and methods for locating blood vessels in the treatment of rhinitis |
| WO2018232338A1 (en) | 2017-06-16 | 2018-12-20 | AesculaTech, Inc. | Thermoresponsive polymers and uses thereof |
| US11147736B2 (en) | 2018-02-26 | 2021-10-19 | Olympic Ophthalmics, Inc. | Therapeutic handheld devices for disorders |
| JP7252204B2 (ja) * | 2018-03-23 | 2023-04-04 | 株式会社 資生堂 | コア－コロナ型ポリマー粒子を用いた化粧料用原料および水中油型乳化化粧料 |
| US12054590B2 (en) | 2018-05-16 | 2024-08-06 | Gl Chemtec Vision Inc. | Hydrogel polymers |
| CN109456444B (zh) * | 2018-10-22 | 2021-03-16 | 西南交通大学 | 一种用于组织修复的黏附导电水凝胶的制备方法 |
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| US11154274B2 (en) * | 2019-04-23 | 2021-10-26 | Decision Sciences Medical Company, LLC | Semi-rigid acoustic coupling articles for ultrasound diagnostic and treatment applications |
| CN112023114A (zh) * | 2019-06-03 | 2020-12-04 | 上海禾思凯尔医疗科技有限公司 | 一种用于泪小管栓塞手术的泪小管阻芯材料及其制备方法 |
| US11065461B2 (en) | 2019-07-08 | 2021-07-20 | Bioness Inc. | Implantable power adapter |
| US11807700B2 (en) | 2020-08-17 | 2023-11-07 | Saudi Arabian Oil Company | Electro-responsive hydrogel for reservoir and downhole application |
| US12253467B2 (en) | 2021-12-13 | 2025-03-18 | Saudi Arabian Oil Company | Determining partition coefficients of tracer analytes |
| US12000278B2 (en) | 2021-12-16 | 2024-06-04 | Saudi Arabian Oil Company | Determining oil and water production rates in multiple production zones from a single production well |
| IL318466A (en) * | 2022-07-20 | 2025-03-01 | Texas Heart Inst | Device and method for cardiac ablation using hydrogel |
| US20240268995A1 (en) * | 2022-10-18 | 2024-08-15 | Modular Thermal Technologies, Llc | Thermal transfer apparatus |
| US12276180B2 (en) | 2023-05-17 | 2025-04-15 | Saudi Arabian Oil Company | Hydrogels for carbon sequestration and sealing zones in a wellbore |
| WO2024249599A2 (en) * | 2023-06-02 | 2024-12-05 | Kayser Laure V | Photo-catalyzed formation of conductive hydrogels |
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| CA2940533A1 (en) | 2015-09-03 |
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| RU2016137744A3 (2) | 2019-03-12 |
| EP3110405B1 (en) | 2020-05-06 |
| RU2698711C2 (ru) | 2019-08-29 |
| CN106470673A (zh) | 2017-03-01 |
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