JP7635724B2 - ベンゼン誘導体の新規結晶形 - Google Patents

ベンゼン誘導体の新規結晶形 Download PDF

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Publication number
JP7635724B2
JP7635724B2 JP2021574120A JP2021574120A JP7635724B2 JP 7635724 B2 JP7635724 B2 JP 7635724B2 JP 2021574120 A JP2021574120 A JP 2021574120A JP 2021574120 A JP2021574120 A JP 2021574120A JP 7635724 B2 JP7635724 B2 JP 7635724B2
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degrees
crystal
compound according
powder
ray diffraction
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JP2021574120A
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Japanese (ja)
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JPWO2021153690A5 (ko
JPWO2021153690A1 (ko
Inventor
修平 大谷
貴之 藤戸
直希 西馬
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Ono Pharmaceutical Co Ltd
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Ono Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021574120A 2020-01-29 2021-01-28 ベンゼン誘導体の新規結晶形 Active JP7635724B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020012075 2020-01-29
JP2020012075 2020-01-29
PCT/JP2021/003092 WO2021153690A1 (ja) 2020-01-29 2021-01-28 ベンゼン誘導体の新規結晶形

Publications (3)

Publication Number Publication Date
JPWO2021153690A1 JPWO2021153690A1 (ko) 2021-08-05
JPWO2021153690A5 JPWO2021153690A5 (ko) 2024-01-12
JP7635724B2 true JP7635724B2 (ja) 2025-02-26

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JP2021574120A Active JP7635724B2 (ja) 2020-01-29 2021-01-28 ベンゼン誘導体の新規結晶形

Country Status (4)

Country Link
JP (1) JP7635724B2 (ko)
KR (1) KR20220132537A (ko)
TW (1) TW202140421A (ko)
WO (1) WO2021153690A1 (ko)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4529119B2 (ja) 2001-08-09 2010-08-25 小野薬品工業株式会社 カルボン酸誘導体化合物およびその化合物を有効成分として含有する薬剤
JP2011503030A (ja) 2007-11-12 2011-01-27 アジェンデ・キミケ・リウニテ・アンジェリニ・フランチェスコ・ア・チ・エレ・ア・エフェ・ソシエタ・ペル・アチオニ 神経因性疼痛に活性な薬物
JP7306392B2 (ja) 2018-07-31 2023-07-11 小野薬品工業株式会社 ベンゼン誘導体
JP7384179B2 (ja) 2020-01-29 2023-11-21 小野薬品工業株式会社 ベンゼン誘導体を含有する医薬組成物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4529119B2 (ja) 2001-08-09 2010-08-25 小野薬品工業株式会社 カルボン酸誘導体化合物およびその化合物を有効成分として含有する薬剤
JP2011503030A (ja) 2007-11-12 2011-01-27 アジェンデ・キミケ・リウニテ・アンジェリニ・フランチェスコ・ア・チ・エレ・ア・エフェ・ソシエタ・ペル・アチオニ 神経因性疼痛に活性な薬物
JP7306392B2 (ja) 2018-07-31 2023-07-11 小野薬品工業株式会社 ベンゼン誘導体
JP7384179B2 (ja) 2020-01-29 2023-11-21 小野薬品工業株式会社 ベンゼン誘導体を含有する医薬組成物

Also Published As

Publication number Publication date
TW202140421A (zh) 2021-11-01
JPWO2021153690A1 (ko) 2021-08-05
WO2021153690A1 (ja) 2021-08-05
KR20220132537A (ko) 2022-09-30

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