JP7673210B2 - 皮膚放射線傷害の予防及び治療のための組成物及び方法 - Google Patents

皮膚放射線傷害の予防及び治療のための組成物及び方法 Download PDF

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JP7673210B2
JP7673210B2 JP2023542836A JP2023542836A JP7673210B2 JP 7673210 B2 JP7673210 B2 JP 7673210B2 JP 2023542836 A JP2023542836 A JP 2023542836A JP 2023542836 A JP2023542836 A JP 2023542836A JP 7673210 B2 JP7673210 B2 JP 7673210B2
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composition
radiation
cri
sertraline
pharmaceutical composition
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JP2023544448A (ja
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エル．ハーディー レジナルト
ブリゲル ミッチェル
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Rythera Therapeutics Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023542836A 2020-09-22 2021-09-22 皮膚放射線傷害の予防及び治療のための組成物及び方法 Active JP7673210B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063081718P 2020-09-22 2020-09-22
US202063081547P 2020-09-22 2020-09-22
US63/081,718 2020-09-22
US63/081,547 2020-09-22
PCT/US2021/051583 WO2022066791A1 (fr) 2020-09-22 2021-09-22 Compositions et méthodes de prévention et de traitement de lésion cutanée radique

Publications (2)

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JP2023544448A JP2023544448A (ja) 2023-10-23
JP7673210B2 true JP7673210B2 (ja) 2025-05-14

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JP2023542836A Active JP7673210B2 (ja) 2020-09-22 2021-09-22 皮膚放射線傷害の予防及び治療のための組成物及び方法

Country Status (7)

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EP (1) EP4217001A4 (fr)
JP (1) JP7673210B2 (fr)
AU (2) AU2021349237B2 (fr)
CA (1) CA3193398A1 (fr)
IL (1) IL301530A (fr)
MX (1) MX2023003357A (fr)
WO (1) WO2022066791A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022351983A1 (en) * 2021-09-22 2024-04-18 Rythera Therapeutics Inc. Composition and method for prevention and treatment of cutaneous radiation injury
CN120091820A (zh) * 2022-09-22 2025-06-03 瑞特拉治疗公司 用于预防和治疗皮肤放射性损伤的组合物和方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030157086A1 (en) 2000-02-15 2003-08-21 Tilly Jonathan L. Protection of the female reproductive system from natural and artificial insults
JP2006524659A (ja) 2003-04-28 2006-11-02 ビーオフロンテラ バイオサイエンス ゲーエムベーハー ケラチノサイトの過剰増殖、特に、アトピー性皮膚炎および乾癬を特徴とする疾患を治療するためのリルゾールの使用
US20180050019A1 (en) 2015-03-06 2018-02-22 Repoceuticals Aps Melatonin for Preventing and Treating Radiation Vaginitis and Proctitis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19621038A1 (de) * 1996-05-24 1997-11-27 Boehringer Ingelheim Kg Aminoguanidine, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Verbindungen enthalten
MXPA06012777A (es) * 2004-05-06 2007-02-14 Cydex Inc Formulaciones de sabor enmascarado que contienen sertralina y eter sulfoalquilico-ciclodextrina.
US7250445B1 (en) * 2005-01-14 2007-07-31 Ehrenpreis Eli D Anti-oxidant suppository for treating radiation proctopathy and other anorectal disorders
PT2114896E (pt) * 2006-12-21 2015-11-04 Peter Maccallum Cancer Inst Compostos radio-protetores e métodos relacionados
US20090156982A1 (en) * 2007-09-06 2009-06-18 Arezou Petrie Transdermal treatment device and method
US9616006B2 (en) * 2007-10-10 2017-04-11 DermaMedics, LLC Methods and compositions for treating dermatological diseases and conditions
US20150353912A1 (en) * 2012-05-31 2015-12-10 Children's Hospital Medical Center Methods for treating and preventing radiation injury using activated protein c polypeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030157086A1 (en) 2000-02-15 2003-08-21 Tilly Jonathan L. Protection of the female reproductive system from natural and artificial insults
JP2006524659A (ja) 2003-04-28 2006-11-02 ビーオフロンテラ バイオサイエンス ゲーエムベーハー ケラチノサイトの過剰増殖、特に、アトピー性皮膚炎および乾癬を特徴とする疾患を治療するためのリルゾールの使用
US20180050019A1 (en) 2015-03-06 2018-02-22 Repoceuticals Aps Melatonin for Preventing and Treating Radiation Vaginitis and Proctitis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Br. J. Clin. Pharmacol.，2020年02月，86(9)，pp.1875-1881，doi: 10.1111/bcp.14238
Jpn. Dent. Sci. Rev.，2020年，56(1)，pp.62-67，doi: 10.1016/j.jdsr.2020.02.001
日本放射線影響学会大会講演要旨集，2007年，Vol.50th ，Page.97, セッションID: CP-121，DOI：https://doi.org/10.11513/jrrsabst.2007.0.201.0

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Publication number Publication date
IL301530A (en) 2023-05-01
WO2022066791A1 (fr) 2022-03-31
AU2025202935A1 (en) 2025-05-15
MX2023003357A (es) 2023-06-30
AU2021349237A1 (en) 2023-06-08
AU2021349237B2 (en) 2025-05-01
JP2023544448A (ja) 2023-10-23
EP4217001A4 (fr) 2024-04-24
EP4217001A1 (fr) 2023-08-02
CA3193398A1 (fr) 2022-03-31

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