JPH01152252U - - Google Patents
Info
- Publication number
- JPH01152252U JPH01152252U JP4822488U JP4822488U JPH01152252U JP H01152252 U JPH01152252 U JP H01152252U JP 4822488 U JP4822488 U JP 4822488U JP 4822488 U JP4822488 U JP 4822488U JP H01152252 U JPH01152252 U JP H01152252U
- Authority
- JP
- Japan
- Prior art keywords
- reactor
- sample
- active reactor
- active
- thermopile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 1
Landscapes
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Radiation Pyrometers (AREA)
Description
第１図は本考案の一実施例の構成を示す説明図
、第２図は第１図のサーモパイルの構造を示す説
明図、第３図は従来の熱量計測型バイオセンサシ
ステムの一例の構成を示す説明図、第４図は従来
のデイフアレンシヤル型方式を示す説明図、第５
図は従来のスプリツトフロー型方式を示す説明図
である。
１……緩衝液、２……送液ポンプ、３……イン
ジエクタ、４……熱交換器、５ａ……活性リアク
タ、５ｂ……参照用リアクタ、６……恒温槽、７
……排出液、９……サーモパイル、９―１……温
接点、９―２……冷接点、１１……増幅器、１２
……表示器。なお図中同一符号は同一または相当
する部分を示す。
Fig. 1 is an explanatory diagram showing the configuration of an embodiment of the present invention, Fig. 2 is an explanatory diagram showing the structure of the thermopile in Fig. 1, and Fig. 3 is an explanatory diagram showing the configuration of an example of a conventional calorimetric biosensor system. Figure 4 is an explanatory diagram showing the conventional differential type system, Figure 5 is an explanatory diagram showing the conventional differential type system.
The figure is an explanatory diagram showing a conventional split flow type system. 1... Buffer solution, 2... Liquid pump, 3... Injector, 4... Heat exchanger, 5a... Active reactor, 5b... Reference reactor, 6... Constant temperature bath, 7
...Drainage liquid, 9...Thermopile, 9-1...Hot junction, 9-2...Cold junction, 11...Amplifier, 12
……display. Note that the same reference numerals in the figures indicate the same or corresponding parts.
Claims (1)
タに緩衝液とともに試料を導入し、試料が上記生
体物質と反応あるいは作用して生ずるエンタルピ
ー変化による上記活性リアクタの温度変化を計測
し、試料の基質を検出する熱量計測型バイオセン
サシステムにおいて、活性リアクタの出口に温接
点を配置し、該活性リアクタの入口（参照用リア
クタを設けたシステムでは参照用リアクタの出口
）に冷接点を配置したサーモパイルまたは赤外線
受光型サーモパイルによつて活性リアクタの温度
変化を計測する構成としたことを特徴とする熱量
計測型バイオセンサシステム。 A sample is introduced together with a buffer into an active reactor in which a biological substance is immobilized on a sub-soluble carrier, and the temperature change in the active reactor due to the enthalpy change caused by the sample reacting or acting with the biological substance is measured, and the substrate of the sample is measured. In a calorimetric biosensor system for detection, a thermopile or an infrared sensor is used, in which a hot junction is placed at the outlet of the active reactor and a cold junction is placed at the inlet of the active reactor (or the outlet of the reference reactor in a system with a reference reactor). A calorimetric biosensor system characterized by being configured to measure temperature changes in an active reactor using a light-receiving thermopile.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4822488U JPH01152252U (en) | 1988-04-12 | 1988-04-12 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4822488U JPH01152252U (en) | 1988-04-12 | 1988-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH01152252U true JPH01152252U (en) | 1989-10-20 |
Family
ID=31274382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4822488U Pending JPH01152252U (en) | 1988-04-12 | 1988-04-12 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01152252U (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62232555A (en) * | 1986-04-02 | 1987-10-13 | Unitika Ltd | Oxygen sensor |
-
1988
- 1988-04-12 JP JP4822488U patent/JPH01152252U/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62232555A (en) * | 1986-04-02 | 1987-10-13 | Unitika Ltd | Oxygen sensor |
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