JPH01250261A - Plastic container for infusion - Google Patents

Abstract

PURPOSE:To improve a natural dripping property by preventing the generation of wrinkles and deformation, by specifying a modulus-of-elasticity ratio calculated by multiplying the ratio of the height of a body part from the bottom part end part to the shoulder part thereof and the outside width of the narrow part of the cross-sectional shape of the body part by the tensile modulus of elasticity of thick plastic wherein the part of the body part from the central part to the vicinity of the bottom part thereof is maximized. CONSTITUTION:A plastic container for infusion consists of a mouth part 2, a shoulder part 3, a body part 4 and a bottom part 5 and the cross-sectional shape of a body part 4 is set to a shape wherein widths in two directions crossing at a right angle are different such as an oval shape and the ratio A/B of the height A from the side end part of the bottom part 5 of the body part 4 to the houlder part 3 thereof and the outside width B of the narrow width part of the cross-sectional shape is set to 2.0<A/B<4.0 and the thickness T of the body part 4 is made max. at the part from the central part in an up-and-down direction to the vicinity of the bottom part 5 and gradually reduced from said part to the mouth part 3 and the bottom part 5 and the modulas of elasticity TXE obtained by multiplying the thickness T of the body part 4 by the tensile modulas of elasticity E of plastic is set to 2<TXE<10.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to a plastic container for infusion containing intravenous infusions such as blood and plasma substitutes.

[Conventional technology]

This type of plastic container for infusions should stand on its own with the bottom facing down when stored before use, and should have good natural dripping properties when placed upside down with the bottom facing up to allow infusions to drip from the mouth. is required.

However, in order to improve self-supporting properties, it is necessary to increase the thickness of the bottom part and increase the rigidity of this bottom part and its vicinity.On the other hand, in order to improve the natural dripping property, the entire container must be It is necessary to make it thin and flexible so that it can be easily deformed by negative pressure, and this self-supporting property and natural dripping property are contradictory performances.

Therefore, the conventional container of this type is
As shown in Publication No. 88, a thin protrusion is formed by partially increasing the blow ratio near the bottom and near the shoulder to create a part that is easy to bend, so that it can be easily bent from this part during natural dripping. There are some that are designed to deform inward.

[Problem to be solved by the invention]

In the above conventional example, if the protrusion is made sufficiently thin in order to improve natural dripping properties, wrinkles will occur in the protrusion when it stands on its own when filled with infusion fluid, resulting in an unsightly appearance. There is a drawback.

The present invention has been developed in consideration of the above-mentioned problems, and has good self-standing properties when filled with infusion fluid, does not cause partial wrinkles or distortion when standing up, and has natural dripping properties. The purpose of this invention is to provide a good plastic container for infusion.

[Means to solve the problem]

In order to achieve the above object, the plastic container for infusion according to the present invention consists of a mouth, a shoulder, a body, and a bottom, and the cross-sectional shape of the body is elliptical, etc., and has different widths in two orthogonal directions. In the shaped plastic container for infusion, the ratio A/B of the height A extending from the bottom end of the body to the shoulder and the narrower outer width B of the cross-sectional shape is 2.0≦A/ B≦4.0, and the wall thickness T of the body is maximized from the center in the vertical direction to the vicinity of the bottom, and gradually becomes thinner from this part toward the 6th part and the bottom. The elastic modulus ratio T×E obtained by multiplying the wall thickness T of the part by the tensile elastic modulus E of the plastic satisfies the following: 2≦T×E≦10.

The plastic container for infusions according to the present invention is not limited to intravenous injections, but can be used in a wide range of applications for administering liquids subcutaneously, intravascularly, intraperitoneally, etc.

[For production]

After filling the plastic container for infusion as described above with 75% of the infusion, it stands on its own with the bottom facing down, and the container is gradually tilted toward a narrower width. In other words, when the self-supporting limit angle was investigated, this self-supporting limit angle was 9 degrees or more. Further, no wrinkles were generated on the torso during this self-supporting process.

A plastic infusion container filled with 75% of the above infusion solution,
Hang the hanging tool on the hook, insert the bottle needle of the infusion supply set into the stopper of the container, and insert the intravenous needle from the position of the bottle needle to the 75CI11. When infusion was dripped from this intravenous needle in the lowered position, the dripping rate was good.

Also, at this time, the container did not become twisted or distorted.

〔Example〕

Embodiments of the present invention will be described based on the drawings.

In the figure, 1 is a plastic container for infusion (hereinafter simply referred to as a container) consisting of a mouth part 2, a shoulder part 3, a body part 4, and a bottom part 5. -8PX) using a blow molding method. The horizontal cross-sectional shape of the mouth part 2 is circular, and the body part is a rectangular shape with four arcuate corners. The bottom part 5 is a flat plane perpendicular to the height direction, and a tongue-shaped hanging tool 6 is protruded from the center so that it can be easily bent. At 5, the container 1 becomes self-supporting.

In the above container 1, when the height from one end of the bottom side of the body 4 to the shoulder 3 is A, and the narrower outer width of the body 4 is B, this height A and the narrower outer width The ratio A/B with B is related to the self-supporting limit angle of the container 1, and the smaller A/B is, the larger the self-supporting limit angle is, and depending on the size of A/B,
Drop rate changes.

In addition, the thickness of the body portion 4 is determined by the tensile modulus of elasticity (JI) of the T1 constituent material.
SK7113) is E, the buckling strength and dripping rate of the container 1 are determined by both. That is, the buckling strength and the dropping rate are determined by the product of both T and E, that is, the elastic modulus ratio TXH.

Below, while changing the above A/BSTxE variously, the body 4
As shown in Fig. 4, the distribution of the wall thickness in the height direction is as follows: type a, which has thicker wall thickness at the center with respect to the vicinity of the mouth part 3 and bottom part 5, and type a, which has thicker wall thickness in the middle part on the bottom side. Type B, which has a thicker wall than other parts, Type C, which has a thinner wall from the mouth 2 side to the bottom 5 side, and Type d, which has a middle part thinner than other parts, are selectively used for molding. In Examples and Comparative Examples, the self-supporting properties, dripping properties, and visual appearance were compared. The results are shown in the table below.

The test methods for self-supporting and dripping properties are as follows.

Self-supporting test method Fill the container 1 with 75% of the volume of infusion solution, seal the mouth and let it stand on its own with the bottom facing down.In this state, tilt it in the narrow direction to find the limit angle at which it will not fall over. It is said to be the self-sustaining limit angle, and the larger this angle, the greater the self-sustaining ability.

Dripping test method A container 1 filled with 75% of the volume of infusion solution is held upside down and hung with a hanging tool 6.
Hang it on a hook, insert the bottle needle of the infusion supply set into the stopper of the container, and insert the intravenous needle 75 minutes from the position of the bottle needle.
The patient is fixed in a position lowered by 1 cm, and infusion fluid is dripped from the intravenous needle. Then, the dripping amount when this dripping is completely completed is DI
This is expressed as a percentage of the amount of infusion that was filled. Appearance visual test method: The container was filled with 75% of the volume of the infusion solution, and the deformation of the appearance was observed.

In each of the above Examples and Comparative Examples, the self-supporting limit angle of the container in each of Examples 1 to 6 was 9 degrees or more, and the self-supporting property was good.

Further, no wrinkles were generated on the torso during this self-supporting process. In addition, good dropping rates were obtained for each of the containers of Examples 1 to 6. And at this time, the container did not become twisted or distorted.

On the other hand, in Comparative Example 1, A/B<2.0 and self-supporting properties were good, but the container was twisted during natural dripping and was accompanied by distorted deformation, resulting in poor dripping properties. The above deformation made the external appearance unsightly and had an adverse effect on mentally unstable patients. Since Comparative Example 2 has A/B > 4.0, the self-supporting limit angle is 5 degrees, which means that the self-supporting property is poor and it easily falls over.

In Comparative Example 3, the buckling strength is low because T×E<2.0, and buckling occurs in the trunk when standing on its own, resulting in inward bending.

In Comparative Example 4, the rigidity of the body was high with TxE>10, resulting in poor dripping properties and a large amount of residual infusion solution.

In Comparative Example 5, since the wall thickness was thin from the center of the body to the bottom, inward folding wrinkles occurred on the side surface of the body near the bottom when the body stood on its own.

In Comparative Example 6, wrinkles occurred on the sides of the body because the center of the body was thinner than the other parts.

〔Effect of the invention〕

The infusion plastic container of the present invention has good self-standing properties when filled with infusion solution, does not wrinkle or become distorted when it stands on its own, and can easily be hung with the hanger 6 on the hook. Good performance was also achieved in the natural dripping of the infusion during infusion.

[Brief explanation of the drawing]

The drawings show an embodiment of the present invention, and FIG. 1 is a front view;
FIG. 2 is a partially broken side view, FIG. 3 is a sectional view taken along the line ■-■ in FIG. 1, and FIG. 4 is a wall thickness distribution diagram from the mouth to the bottom. 1 is a plastic container for infusion, 2 is a mouth part, 3 is a shoulder part, 4
is the body, 5 is the bottom, and 6 is the hanging tool. Applicant Kyora Ri Co., Ltd. Agent Patent Attorney Masaaki Yonehara

Claims (1)

[Claims] Consists of a mouth portion 2, a shoulder portion 3, a body portion 4, and a bottom portion 5, and the body portion 4
In a plastic infusion container whose cross-sectional shape is different in width in two orthogonal directions, such as an ellipse, the height A extending from the bottom side end of the body 4 to the shoulder 3 and the narrow width of the cross-sectional shape The ratio A/B to the outer width B of the outer side is set to 2.0≦A/B≦4.0, and the wall thickness T of the body portion 4 is maximized from the center in the vertical direction to the vicinity of the bottom. The wall gradually becomes thinner as it goes from the part to the mouth part 2 and bottom part 5,
Furthermore, an elastic modulus ratio T×E obtained by multiplying the wall thickness T of the body portion 4 by the tensile elastic modulus E of the plastic satisfies the following: 2≦T×E≦10.