JPH01283205A - Cosmetic - Google Patents
CosmeticInfo
- Publication number
- JPH01283205A JPH01283205A JP63110520A JP11052088A JPH01283205A JP H01283205 A JPH01283205 A JP H01283205A JP 63110520 A JP63110520 A JP 63110520A JP 11052088 A JP11052088 A JP 11052088A JP H01283205 A JPH01283205 A JP H01283205A
- Authority
- JP
- Japan
- Prior art keywords
- cosmetic
- hyaluronate
- squalane
- ethanol
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002537 cosmetic Substances 0.000 title claims abstract description 20
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 10
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 claims abstract description 7
- 229940014041 hyaluronate Drugs 0.000 claims abstract description 7
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229940032094 squalane Drugs 0.000 claims abstract description 6
- 239000007864 aqueous solution Substances 0.000 claims abstract description 5
- 230000000694 effects Effects 0.000 abstract description 6
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract description 3
- 229920002674 hyaluronan Polymers 0.000 abstract description 3
- 229960003160 hyaluronic acid Drugs 0.000 abstract description 3
- 239000006210 lotion Substances 0.000 abstract description 3
- 239000003795 chemical substances by application Substances 0.000 abstract description 2
- 238000013329 compounding Methods 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 229960004756 ethanol Drugs 0.000 abstract 1
- 239000002304 perfume Substances 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 230000002633 protecting effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 230000003020 moisturizing effect Effects 0.000 description 5
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 229920002683 Glycosaminoglycan Polymers 0.000 description 2
- 229960000458 allantoin Drugs 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 210000000434 stratum corneum Anatomy 0.000 description 2
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- -1 alkali metal salt Chemical class 0.000 description 1
- 239000000490 cosmetic additive Substances 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- BITYAPCSNKJESK-UHFFFAOYSA-N potassiosodium Chemical compound [Na].[K] BITYAPCSNKJESK-UHFFFAOYSA-N 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 description 1
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
用を有し、安全にして全長に適用できることを特徴とし
た化粧料に関する。DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to a cosmetic that is characterized in that it has a wide range of uses and can be safely applied to the entire body.
保湿メカニズムについて複雑な因子が絡む為、未だ不明
な点が多く残されている。一般に保湿剤としてグリセリ
ン、ピロリドンカルボン酸ナトリウム、乳酸ナトリウム
等を配合した化粧料が用いられてきた。また、従来ムコ
多糖類、アラントイン、コラ−ケンや種Ｊｌ？の植物抽
出物等が肌あれ防止、創傷治癒等の効果を有するとして
化粧料に配合する試みがなされてきた（特開昭５７−１
８３７０７４他）。一方スクアランは化学的にも微生物
学的にもまた他の配合原料に対しても不活性なきわめて
安定である為基礎化粧用油性原料として用いられている
。Since the moisturizing mechanism involves complex factors, many points remain unclear. Cosmetics containing glycerin, sodium pyrrolidone carboxylate, sodium lactate, etc. as humectants have generally been used. In addition, conventional mucopolysaccharides, allantoin, Kolaken and Seed Jl? Attempts have been made to incorporate plant extracts and the like into cosmetics as having effects such as preventing rough skin and healing wounds (Japanese Unexamined Patent Publication No. 57-1
837074 and others). On the other hand, squalane is used as an oil-based raw material for basic cosmetics because it is extremely stable and chemically and microbiologically inert to other ingredients.
しかしながら、いわゆる保湿剤は水分を角質層に供給す
るという機能は有するが、−１１寺的な効果しかなく、
低湿度環境下では逆に角質層から水分を奪うという欠点
を有している。またムコ多糖類、アラントイン、コラ−
リンや植物抽出物等は前述した如く、優れた美容効果を
有するものであるが来た満足ずべき保湿効果を有するも
のが得られておらず、種々研究されているのか現状であ
る。その為各種原料を多数組みあわせた化粧料か売られ
ていて、しかも近年安全性の高いものかつくられてきた
か来た化粧品に関する苦情か多いのが現実である。However, although so-called moisturizers have the function of supplying moisture to the stratum corneum, they only have a negative effect.
In low humidity environments, it has the disadvantage of depriving the stratum corneum of moisture. Also mucopolysaccharide, allantoin, kola-
As mentioned above, phosphorus, plant extracts, etc. have excellent beauty effects, but at present no one with a satisfactory moisturizing effect has been obtained, and various studies are still being conducted. For this reason, cosmetics are being sold that are made from a large number of combinations of various raw materials, and the reality is that there are many complaints about cosmetics that have been made from highly safe products in recent years.
本発明者らは係る点に鑑み、優れた保湿効果を有し、し
かも全身に適用できる安全な化粧料を得るべく鋭意研究
した結果、エタノール、ヒアルロン酸塩およびスフロラ
ンの三成分を組合わせることで極めて顕著な保湿効果が
得られ、安全でしかも全身に適用できることを見出し、
本発明を完成するに到った。即ち本発明の化粧料は保湿
効果に優れ、皮膚の保護効果を有し、しかも安心して全
身に適用できる全身美容に適する化粧料を提供するもの
である。本発明において使用されるヒアルロン酸塩とは
ヒアルロン酸ナトリウムカリウム塩等のヒアルロン酸の
アルカリ金属塩が好ましく、平均分子量は約２０００〜
約３００万好ましくは約１万〜２００万、より好ましく
は 〜である。本発明の化粧品中における含量は約０
．０１％〜約２重量％であり、０．１〜０．３重量％の
範囲が使用感また効果上好ましい。スクアランの量は本
発明の化粧料全量に対し約１〜約２０％（Ｖ／Ｖ）の範
囲であり、好ましくは約５〜約７％（Ｖ／Ｖ）である。In view of the above, the present inventors conducted extensive research in order to obtain a safe cosmetic that has excellent moisturizing effects and can be applied to the entire body. We discovered that it has an extremely significant moisturizing effect, is safe, and can be applied to the entire body.
The present invention has now been completed. That is, the cosmetic composition of the present invention has an excellent moisturizing effect, a skin protection effect, and can be safely applied to the whole body and is suitable for whole body beauty. The hyaluronate used in the present invention is preferably an alkali metal salt of hyaluronic acid such as sodium potassium hyaluronate, and has an average molecular weight of about 2,000 to 2,000.
About 3 million, preferably about 10,000 to 2 million, more preferably ~. The content in the cosmetics of the present invention is approximately 0
．． 01% to about 2% by weight, and a range of 0.1 to 0.3% by weight is preferable from the viewpoint of feeling of use and effectiveness. The amount of squalane ranges from about 1 to about 20% (V/V), preferably from about 5 to about 7% (V/V), based on the total amount of the cosmetic composition of the present invention.
エタノールは１〜２０％（■ハ）の範囲であり、好まし
くは約３〜約６％（Ｖ／Ｖ）の範囲である。Ethanol is in the range of 1 to 20% (■), preferably in the range of about 3 to about 6% (V/V).
本発明の化粧料は必要に応じて更に香料などの化粧品用
の添加剤、配合剤などをＯ〜約５０％（重量）、好まし
くは約３０％（重１１）以下、ローションなどの化粧水
として用いるときは、約５％（重量）以下含んでいても
よい。The cosmetic of the present invention may further contain cosmetic additives and compounding agents such as fragrances, etc., in an amount of 0 to about 50% (by weight), preferably about 30% (by weight) or less, as a lotion such as a lotion. When used, it may contain up to about 5% (by weight).
本発明の化粧料の残部は水である。The remainder of the cosmetic composition of the present invention is water.
０．２％ヒアルロン酸すトす１クム水溶液９０部（容量
）に、水溶液量に対し、スクアラン６部（容量）、エタ
ノール４部（容量）を加え、振盪して混合し本発明の化
粧料を得た。To 90 parts (volume) of a 0.2% hyaluronic acid 1 cum aqueous solution, 6 parts (volume) of squalane and 4 parts (volume) of ethanol are added to the amount of the aqueous solution and mixed by shaking to prepare the cosmetic of the present invention. I got it.
本発明の化粧料の作用効果につき使用テストにより試験
を行った。使用テストは乾燥肌の女性５人、髪がばさつ
く女性５人、ストッキングをはくときかかとが荒れトス
ツキングがはきにくかったり、電図しやすい女性５人に
ついてそれぞれ風呂上がり後毎日１週間使用してもらっ
た後使用域を調査した。その結果は表ＩＱ表３に示す。The effects of the cosmetics of the present invention were tested through use tests. The test was conducted on 5 women with dry skin, 5 women with frizzy hair, and 5 women whose heels get rough when wearing stockings, and who tend to get irritated when wearing stockings.The product was used every day for one week after taking a bath. After receiving the information, I investigated the area in use. The results are shown in Table IQ Table 3.
表１゜
表２゜
表３゜
このように髪から足まで全身に同じ液が利用でき、しか
も有効であった。Table 1゜Table 2゜Table 3゜In this way, the same liquid could be used all over the body from the hair to the feet, and it was effective.
Claims (1)
することを特徴とする化粧料Cosmetics characterized by containing a hyaluronate aqueous solution, squalane and ethanol
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63110520A JPH01283205A (en) | 1988-05-09 | 1988-05-09 | Cosmetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63110520A JPH01283205A (en) | 1988-05-09 | 1988-05-09 | Cosmetic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH01283205A true JPH01283205A (en) | 1989-11-14 |
Family
ID=14537880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63110520A Pending JPH01283205A (en) | 1988-05-09 | 1988-05-09 | Cosmetic |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH01283205A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE1020210A3 (en) * | 2011-09-06 | 2013-06-04 | Auriga Internat | DERMATOLOGICAL COMPOSITION BASED ON FRAGMENTS OF HYALURONATE OR HYALURONIC ACID. |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59102880U (en) * | 1982-12-28 | 1984-07-11 | 坂本工業株式会社 | Slider button on wind regulator |
| JPS62135770U (en) * | 1986-02-19 | 1987-08-26 |
-
1988
- 1988-05-09 JP JP63110520A patent/JPH01283205A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59102880U (en) * | 1982-12-28 | 1984-07-11 | 坂本工業株式会社 | Slider button on wind regulator |
| JPS62135770U (en) * | 1986-02-19 | 1987-08-26 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE1020210A3 (en) * | 2011-09-06 | 2013-06-04 | Auriga Internat | DERMATOLOGICAL COMPOSITION BASED ON FRAGMENTS OF HYALURONATE OR HYALURONIC ACID. |
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