JPH01500059A - アッセイ - Google Patents

アッセイ

Info

Publication number
JPH01500059A
JPH01500059A JP62503051A JP50305187A JPH01500059A JP H01500059 A JPH01500059 A JP H01500059A JP 62503051 A JP62503051 A JP 62503051A JP 50305187 A JP50305187 A JP 50305187A JP H01500059 A JPH01500059 A JP H01500059A
Authority
JP
Japan
Prior art keywords
signal
assay
reagent
assay method
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62503051A
Other languages
English (en)
Japanese (ja)
Inventor
デイビス，ポール・ジエイムズ
ドレイク，ロウズマリ・アン・ルーシ
ホーンビイ，ウイリアム・エドワード
Original Assignee
ユニリーバー・ナームローゼ・ベンノートシヤープ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868612458A external-priority patent/GB8612458D0/en
Priority claimed from GB868620894A external-priority patent/GB8620894D0/en
Application filed by ユニリーバー・ナームローゼ・ベンノートシヤープ filed Critical ユニリーバー・ナームローゼ・ベンノートシヤープ
Publication of JPH01500059A publication Critical patent/JPH01500059A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP62503051A 1986-05-22 1987-05-21 アッセイ Pending JPH01500059A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8612458 1986-05-22
GB868612458A GB8612458D0 (en) 1986-05-22 1986-05-22 Assays
GB8620894 1986-08-29
GB868620894A GB8620894D0 (en) 1986-08-29 1986-08-29 Assays

Publications (1)

Publication Number Publication Date
JPH01500059A true JPH01500059A (ja) 1989-01-12

Family

ID=26290800

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62503051A Pending JPH01500059A (ja) 1986-05-22 1987-05-21 アッセイ

Country Status (4)

Country Link
EP (1) EP0247796A1 (fr)
JP (1) JPH01500059A (fr)
AU (1) AU7399487A (fr)
WO (1) WO1987007386A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500100A (ja) * 1991-10-09 1995-01-05 レイラス　オイ ヌクレオシド誘導体の製造方法

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
GB8817387D0 (en) * 1988-07-21 1988-08-24 Lim P L Method for detecting antigens
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5063081A (en) * 1988-11-14 1991-11-05 I-Stat Corporation Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
ZA92803B (en) 1991-02-06 1992-11-25 Igen Inc Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets
IL100867A (en) * 1991-02-06 1995-12-08 Igen Inc Method and apparatus for improved luminescence assays
US5242833A (en) * 1991-03-20 1993-09-07 Reference Diagnostics, Inc. Lipid fractionation
ATE184320T1 (de) * 1991-07-10 1999-09-15 Igen Int Inc Verfahren für verbesserte lumineszenz-assays unter verwendung von teilchenkonzentration und chemilumineszenznachweis
US5538852A (en) * 1992-10-02 1996-07-23 Ecochem Research, Inc. Immunoassay for polychlorinated biphenyls
US5744320A (en) * 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence
US5753517A (en) * 1996-03-29 1998-05-19 University Of British Columbia Quantitative immunochromatographic assays
US6165798A (en) * 1996-10-10 2000-12-26 University Of British Columbia Optical quantification of analytes in membranes
US6200531B1 (en) 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
CA2366651C (fr) 1999-03-19 2010-11-23 Kurokawa, Kiyoshi Procede de detection de proteine megsine et son utilisation
US7118878B1 (en) 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
KR20050013592A (ko) 2002-06-20 2005-02-04 아이젠인터내셔널인코포레이티드 전기화학발광 유동 셀 및 유동 셀 성분
GB0214947D0 (en) * 2002-06-28 2002-08-07 Secr Defence Assay
US7041401B2 (en) 2002-10-18 2006-05-09 University Of Iowa Research Foundation Magnetically modified electrodes containing at least one catalyst component that mediates a subatomic particle transfer process
JP5590796B2 (ja) 2005-06-03 2014-09-17 ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム 電気化学および単一ファラデー電極による電気化学発光
US9657290B2 (en) 2012-07-03 2017-05-23 The Board Of Trustees Of The Leland Stanford Junior University Scalable bio-element analysis
WO2016134370A1 (fr) 2015-02-22 2016-08-25 The Board Of Trustees Of The Leland Stanford Junior University Appareil, procédé et produits de microcriblage
WO2018089953A1 (fr) 2016-11-14 2018-05-17 Orca Biosystems, Inc. Procédés et appareils de tri de particules cibles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115535A (en) * 1977-06-22 1978-09-19 General Electric Company Diagnostic method employing a mixture of normally separable protein-coated particles
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
CA1185177A (fr) * 1981-07-17 1985-04-09 Larry E. Morrison Technique immunochimique basee sur le transfert d'energie non rayonnante
CA1209889A (fr) * 1981-09-18 1986-08-19 Litai Weng Essai homogene sur une surface non poreuse
US4687735A (en) * 1983-03-14 1987-08-18 Syntex (U.S.A.) Inc. Enzymatic poly-reactant channeling binding assay
GB8401368D0 (en) * 1984-01-19 1984-02-22 Amersham Int Plc Assay method
JPH0619348B2 (ja) * 1984-06-15 1994-03-16 マスト イミユノシステムズ インコ−ポレ−テツド 発光特異結合検定に於いて外部光を抑制する減衰剤
AU596946B2 (en) * 1984-07-10 1990-05-24 F. Hoffmann-La Roche Ltd Methods of assay
FI842992A0 (fi) * 1984-07-26 1984-07-26 Labsystems Oy Immunologiskt definitionsfoerfarande.
GB8423227D0 (en) * 1984-09-14 1984-10-17 Unilever Plc Materials for specific binding assays
FI850481A0 (fi) * 1985-02-06 1985-02-06 Labsystems Oy Foerfarande foer bestaemning av motmedel eller antigener.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500100A (ja) * 1991-10-09 1995-01-05 レイラス　オイ ヌクレオシド誘導体の製造方法

Also Published As

Publication number Publication date
EP0247796A1 (fr) 1987-12-02
WO1987007386A1 (fr) 1987-12-03
AU7399487A (en) 1987-12-22

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