JPH0215018A - Hair nourishing and hair growing agent - Google Patents

Abstract

PURPOSE:To obtain a hair nourishing and hair growing agent having excellent effects on hair nourishment, hair growth, prevention of hair removal, etc., containing an essence of Swertiapseudochinensis Hara as an active ingredient. CONSTITUTION:An essence obtained by extracting Swertiapseudochinensis Hara as an active ingredient in a flowering period with a lower alcohol, water, etc., as an active ingredient is blended with an alcohol, wetting agent or humectant, oily component and, if necessary, dyestuff, perfume, germicide, antiseptic, etc., properly to give the aimed substance. The essence in a state of extracted solution can be used as it is by method of sprinkling on hair and scalp and massaging. The amount of Swertiapseudochinensis Hara blended is 1-20wt.% calculated as unpurified solid substance.

Description

[Detailed description of the invention] [Industrial application field] The present invention relates to a hair nourishing agent.

[Conventional technology]

Conventionally, hair nourishing/growth agents containing various medicinal ingredients have been commercially available. There are many substances known to be effective for hair growth and growth, the most representative of which are salicylic acid, urea, resorcinol, glycyrrhizic acid,
Keratolytic agents, bactericidal agents, anti-inflammatory agents such as purple root extract; hair matrix activators such as amino acids and estradiol; carpronium chloride as a peripheral vasodilator and blood circulation promoting agent;
Vitamin E1 acetylcholine derivatives; other natural product extracts such as carrot extract, reishi extract, and Japanese cabbage extract.

Hair nourishing/growth agents usually contain a suitable combination of the above-mentioned medicinal ingredients for the purpose of keeping the scalp healthy and delaying aging as much as possible. however,
There are few products that show satisfactory effects in preventing and preventing dandruff, itching, and hair loss, as well as promoting hair growth.
Improvement of the layer is desired.

[Problem to be solved by the invention]

An object of the present invention is to provide a novel hair nourishing agent that is excellent in effects such as hair nourishing, hair growth, and hair loss prevention.

[Means to solve the problem]

As a result of extensive research in order to achieve the above object, the present inventors have discovered that Svertiipse extract (Svertiipse
ud.

The present inventors have discovered that hair growth (chine++sis Hara) exhibits remarkable effects on hair growth and hair growth, and have completed the present invention. That is, the hair nourishing/hair growth agent provided by the present invention contains an extract of Japanese cabbage as an active ingredient.

The purple flower extract used in this invention is the extract obtained by extracting the dry and pulverized product of the whole flowering flowering flowering plant with lower alcohol, purified water, or water-containing lower alcohol, and filtering the residue, or the solids therein. ,
Or they have been purified to remove sugar and other non-medicinal ingredients. Purple cabbage extract is
Even if you sprinkle the extract directly on your hair and scalp and use it as a pine surge, it is effective for hair growth.

In the hair nourishing and hair restoring agent of the present invention, as the hair restoring and hair restoring agent components other than the purple cabbage extract, any of those conventionally used in hair restoring and hair restoring agents can be used. For example, alcohols such as ethanol (standard amount: about 60-80% by weight), humectants or humectants such as glycerin, propylene glycol, polypeptide, amino acids (standard amount: about 5-15% by weight), castor oil, liquid paraffin, fatty acids. Oil-based ingredients such as esters to make hair glossy can be used.

Furthermore, if necessary, pigments, fragrances, bactericidal agents, preservatives, keratolytic agents, anti-androgens, antioxidants, etc. may be appropriately added within the range that does not impede achievement of the objectives of the present invention.

The preferred blending amount of the common japonica extract in the hair nourishing agent is 1 to 20% by weight, particularly preferably 2 to 10% by weight, as an unrefined solid.

〔Example〕

A hair growth agent with the following composition was prepared, and a hair growth promoting effect test was conducted using guinea pigs.

Medicinal ingredients shown in Table 1 2.0 parts Ethanol 80 parts Castor oil 10 parts Propylene glycol 2 parts Liquid paraffin 0.5 parts Purified water Remaining amounts to make the total 100 parts Table 1 Additive-free α-Tocopherol Glycyrrhizinate Hinokitiol Ethinyl Estradiol Pantothenic acid biotin Purple cabbage extract ■ Purple cabbage extract ■ Comparative example 1 Comparative example 2 Comparative example 3 Comparative example 4 Comparative example 5 Comparative example 6 Comparative example 7 Example 1 Example 2 Example 3 Purple cabbage extract ■ Hair growth agent is prepared by adding and dissolving each component other than water in ethanol (dissolving the fragrance etc. in a solubilizer) according to the conventional method, and then adding purified water with a small amount of chelating agent added while stirring. The method was to homogenize and finally filter. The method for preparing the purple cabbage extract used in the preparation of the example products and the method for testing the hair growth promoting effect are as follows.

Extract for Example 1■: 50g of dried and crushed whole plant of the flowering stage of the flowering period was mixed with 750ml of 90v/v% ethanol.
Extraction was carried out for 2 days at room temperature. Solid and liquid were separated by filtration, and the same extraction operation was repeated three times on the extraction residue.

The obtained extracts were combined and concentrated under reduced pressure, and ethanol and purified water were added to the concentrate (solid content 5.4 g) to give an ethanol concentration of 70 v/v% and a total volume of 501 g. Adjusted to. Thereafter, the mixture was allowed to stand at 5° C. for one week, and insoluble matter was filtered off, and the filtrate was dried under reduced pressure to obtain 4.2 g of a purple cabbage extract.

Extract for Example 2 (■): 50 g of dried and pulverized whole plant of the flowering stage of the Japanese commonweed was immersed in 50v/v% ethanol 7501 and extracted at 40-50°O for 1 hour. The solid and liquid were separated by filtration, and the same extraction operation was repeated three times for the extraction residue. The obtained extracts were combined and concentrated under reduced pressure, and ethanol and purified water were added to the obtained concentrate (solid content 10.5 g) to bring the ethanol concentration to 70 v/v.
%, and the total volume was adjusted to 50ml. Thereafter, the mixture was allowed to stand at 5° C. for one week, and insoluble matter was filtered off, and the filtrate was dried under reduced pressure to obtain 7.4 g of a purple cabbage extract.

Extract for Example 3 (■): 50 g of dried and pulverized whole plant of the flowering stage of the Japanese commonweed was immersed in purified water 7501 at 80 to 90° C. and extracted for 1 hour. Solid and liquid were separated by filtration, and the same extraction operation was repeated three times on the extraction residue.

The obtained extracts were combined and concentrated under reduced pressure, and ethanol and purified water were added to the obtained concentrate (solid content to, og) to bring the ethanol concentration to 50 v/v% and the total volume to 50 ml. It was adjusted. Thereafter, the mixture was allowed to stand at 5° C. for one week, and insoluble matter was filtered off, and the filtrate was dried under reduced pressure to obtain 6.5 g of a purple cabbage extract.

Hair growth promoting effect test method: Five male Hartley guinea pigs (weight 250-350 g) are used for each sample.

After cutting the Mormont's back with electric clippers, the hair is completely removed using hair removal cream. Apply the sample to the hair removal area once every morning for 4 weeks. The hair growth effect is determined by measuring the length of 20 hairs for each animal from 1 week to 4 weeks after hair removal and the length of hair that grows every week during the test period, and calculating the average value. .

The test results are shown in Table 2.

Table 2 Hair length measurement results (unit: mm) From this result,
The hair nourishing/hair growing agent that contains the purple cabbage extract has a significantly superior hair growing effect compared to Comparative Example 1, which does not contain any medicinal ingredients, as well as hair nourishing/hair growing agents that contain other medicinal ingredients. It can be seen that it has

〔Effect of the invention〕

The hair nourishing/growth agent of the present invention is safe as it contains as an active ingredient an ingredient extracted from a natural product, Physcomitrella japonica, and is also highly effective in its use.
It is expected that this product will be effective even for people for whom conventional hair growth products have not had much effect.

Claims (1)

[Claims] A hair nourishing/growth agent characterized by containing an extract of Japanese cabbage as an active ingredient.