JPH02223506A - Cosmetic containing liquid crystal - Google Patents

Abstract

PURPOSE:To obtain the subject cosmetic capable of color development in the skin temperature range without fail and having an improved water-holding property by dispersing a composition of cholesteryl heptanoate, cholesteryl 12-hydroxystearate, etc., into a transparent or semitransparent cosmetic. CONSTITUTION:A liquid crystal composition prepared by blending cholesteryl heptanoate or cholesteryl orate with cholesteryl 12-hydroxystearate, or blending a mixture of cholesteryl heptanoate and cholesteryl 12-hydroxystearate with one or more selected from cholesteryl heptanoate, cholesteryl orate, cholesteryl butylate, cholesteryl laurate, etc., is dispersed into a transparent or semitransparent cosmetic. The resultant cosmetic has an apparent fun that color development changes by light, temperature, etc., in addition thereto, shows a beautiful gloss color similar to a pearl, has safety enough to be free from irritation to the skin and has an excellent heat retaining property, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to improvements in cholesteric liquid crystal cosmetic formulations. More specifically, the present invention relates to improved cosmetics using cholesteric liquid crystals that have better color development in the skin temperature range, do not irritate the skin, and have improved water-holding ability.

[Conventional technology]

JP-A-57-32211 No. 33 discloses cholesteric liquid crystal formulations. It is a formulation of cholesteric liquid crystal compounds containing at least two cholesteric esters of cholesterol suspended in an oily carrier or an aqueous emulsion and which produces various colors when subjected to shear action.

] As the cholesterol ester, there are many fatty acid esters of cholesterol, but preferred esters include cholesteryl pelargonate, cholesteryl benzoate, cholesteryl cinnamate, and cholesteryl cinnamate.
Cholesteryl adipate, cholesteryl p-nitrobenzoate, cholesteryl 3,4-dinitrobenzoate, cholesteryl 2-ethylhexanoate, and cholesteryl chloride are listed. This publication also discloses that because cholesteric substances are usually liquid crystals of cholesterol, these substances are readily absorbed into the skin and are preferred ingredients for cosmetic formulations.

JP-A-62-53910 Tan discloses a liquid crystal type based on a one-phase liquid crystal Ifll structure obtained from a hydrophilic di-ionic surfactant, a water-soluble substance having a hydroxyl group in the molecule, an oil component, and water. An oil-based cosmetic is disclosed. These include hydrophilic nonionic surfactants such as polyoxyethylene sorbitan fatty acid esters and ethylene oxide derivatives of glycerin fatty acid esters, and water-soluble substances that have hydroxyl groups in their molecules such as ethylene oxide or propylene oxide adducts of sugar derivatives. It is a one-phase liquid crystal structure consisting of oil components and water, and is not only unrelated to Nisdel cholesterol, but also used as a cosmetic to improve the feel of cosmetics, such as cleansing cream and pine surge cream. However, the coloring properties of liquid crystals are not utilized.

JP-A No. 62-96585 also discloses a lamellar liquid crystal structure obtained from an ethylene oxide additive of a Guerbet type alcohol having an HLB of 10 or higher, a polyhydric alcohol having a valence of 3 or more, an oil component and water. This also has nothing to do with cholesterol esters, and is used to improve the feel of cosmetics as cleansing creams and pine surge creams, and does not utilize the coloring properties of liquid crystals.

JP-A No. 61-57838 discloses an esterification product of an intermolecular oligoesterified carboxylic acid of 12-hydroxystearic acid and/or ricinoleic acid and a sterol, and one or more of these products. It is a cosmetic made from

Although it is related to 12-hydroxystearic acid, it is an ester of its intermolecular oligoesterified carboxylic acid and a sterol, and is not cholesteryl 12-hydroxystearic acid.

It also exhibits excellent affinity and texture to the skin, and has emulsifying, water-retaining, and moisturizing properties that are far superior to conventional sprawl esters, making it suitable for use in cosmetics and as an oil for external use. However, it does not utilize the color development properties of liquid crystals. The applicant filed a patent application in 1986-7.
No. 1917, they applied for a cosmetic containing a liquid crystal composition containing cholesteryl 12-stearate, and as a result of further research, they obtained research results that should supplement this.

[Problem to be solved by the invention]

The present inventors conducted a follow-up study of JP-A-57-32211, and some of the products described in this publication include cholesteryl isostearyl carbonate, such as cholesteryl chloride and cholesteryl nonanoate, which are particularly preferred embodiments. It has been found that the combination is unfavorable from the point of view of irritation to the skin, that is, from the point of view of safety.

Furthermore, the cholesteryl esters exemplified in the publication are said to be able to produce color by blending at least two of them, but depending on the combination, the temperature may range from 0°C to 30°C, depending on the outside temperature. We have discovered that some products do not develop color in the human skin temperature range.

It has also been found that the restyryl ester exemplified in the publication is not necessarily satisfactory in terms of emulsifying properties, water-holding properties, and moisturizing properties required when used as a cosmetic.

The present invention aims to solve these problems.
That is, the object of the present invention is to provide a combination of multiple choleszolyl nisdels that reliably develops color in the human skin temperature range of O'C to 30°C and does not cause any irritation to the skin. The object of the present invention is to provide a cosmetic containing a liquid crystal that has much better emulsifying properties, water-retaining properties, and moisturizing properties than the above-mentioned cholesteryl esters.

[Failure to solve the problem]

The present inventors conducted extensive research to solve these problems. As a result, when cholesteryl 12-hydroxystearate is used as one of the cholesteryl esters to be blended, it produces color even in combinations that would not produce color as a liquid crystal without it, and is also satisfactory in terms of skin irritation and water retention. The present invention was completed with the desired results.

That is, the present invention is a cosmetic product containing a liquid crystal obtained by dispersing a liquid crystal composition containing cholesteryl heptanoate and ressolyl 12-hydroxystearate in a transparent or translucent cosmetic product.

The present invention is also a cosmetic containing liquid crystal, which is obtained by dispersing a liquid crystal composition containing cholesteryl oleate and cholesteryl 12-hydroxystearate in a transparent or translucent cosmetic.

Also, cholesteryl heptanoate and cholesteryl 12-
A liquid crystal composition containing hydroxystearate 1 and at least one selected from the group consisting of lorestaryl hebutanoate, cholesteryl oleate, cholesteryl butyrate, cholesteryl laurate, cholesteryl decanate, and cholesterifrenonanony 1. A cosmetic containing liquid crystals dispersed in a transparent or translucent cosmetic.

Furthermore, the present invention is a cosmetic containing a liquid crystal obtained by dispersing in a transparent or semi-transparent cosmetic a liquid crystal composition containing lerestyrylone, cholesteryl 12 hydroxystearate, and cholesteryl heptanoate.

Group J consisting of cholesteryl oleate, cholesteryl butyrate, reszolyl laurate, cholesteryl decanate, and cholesteryl nonanoate: A liquid crystal containing two or more of the following, especially cholesteryl 12 hydroxystearate-1. The composition has already been filed by the present applicant in the aforementioned Japanese Patent Application No. 6371917.

The present invention relates to a liquid crystal cosmetic composition containing, as a base, a liquid crystal composition of restyryl 12-hydroxystearate 1~ cholesteryl oleate and cholesteryl heptanony 1~.

Similar liquid crystal compounds are exemplified in JP-A-57-32211, but for safety reasons, most of them do not develop color when combined with substances other than cholesteryl chloride. However, there are many combinations that produce color when cholesteryl 12-hydroxystearate is blended, and even in combinations of two types of cholesteryl heptanoate and cholesteryl 12-hydroxystearate, the ratio of cholesteryl 12-hydroxystearate is 2/3 or more. It was found that the color develops.

Even if cholesteryl 12-hydroxystearate is omitted from the formulation of the present invention, some colors may develop depending on the combination, but by adding cholesteryl 12-hydroxystearate, the humidity range of coloring can be expanded and the coloring can be further enhanced. In addition, as described below, cholesteryl 12 hydroxystearate contains 5 of the other ingredients.
It has the advantage of exhibiting more than double the water-holding capacity, and is used as a cosmetic raw material.
A mixture containing this is extremely superior.

For example, a 1:1 combination of cholesteryl heptanoate and cholesteryl nonanoate produces color, but when cholesteryl 12-hydroxystearate is added to this, the color develops over a wider temperature range and becomes more vivid, and has an extremely high water-holding ability. ing.

The mechanism of light emission is explained in detail in the above publication, but in short, cholesteryl esters exhibit a cholesteric liquid crystal phase. That is, the cholesteric phase is a twisted form of the nematic phase. Although there are no layers and the molecules are arranged randomly, the direction in which parallel molecules are aligned becomes twisted as they pass through the cholesteric phase. In other words, it resembles the steps of a spiral staircase, and this liquid crystal selects and reflects only a certain wavelength of light corresponding to the spiral pitch, that is, a certain color, which gives the liquid crystal a unique color.

It is known that the coloring temperature range of one type of cholesteryl ester alone is relatively narrow, but the temperature range can be widened by combining two or more types of cholesteric liquid crystal materials.

Two or more types of cholesteryl esters and cholesteryl 12-
Cholesteryl esters suitable for combination into hydroxysdeare 1 include cholesteryl oleate, cholesteryl butyrate, cholesteryl plaurate, cholesteryl nonanoate, cholesteryl heptanoate, cholesteryl ester. Examples include Ruhebutanoe-1.

Among these, restyryl heptanoate (to cholesteryl oleate-1) develops color at the temperature of human skin or room temperature even when it is alone combined with cholesteryl 12-hydroxystearate.

These cholesteryl fatty acid esters are components that are present in human skin or are naturally present, and their inclusion in cosmetics is highly beneficial for the skin. Among them, the cholesteryl ester of the present invention has been confirmed to be safe for the skin.

Furthermore, when cholesteryl 12-hydroxystearate of the present invention is added, the effect increases depending on the amount added, compared to cholesteryl stearate and cholesteryl oleate, but when added in an amount of 2 to 4%, the water holding capacity is 5 times or more.

When the liquid crystal formulation of the present invention is used as a cosmetic, the liquid crystal formulation is used as a base, and water, which is commonly used in cosmetics, etc.
Water-soluble substances with hydroxyl groups in the molecule, fatty acids, fatty acid esters, higher alcohols, antioxidants, preservatives, other medicinal agents, pigments, fragrances, etc., are added as necessary when compounding the liquid crystal compound, or when compounding the liquid crystal compound. It is prepared by later blending.

Glycerin is a water-soluble substance that has a hydroxyl group in its molecule.
1.3 Butylene glycol, decaglycerin monostearate, propylene glycol, ethylene glycol,
Examples include lauric acid jetanolamide, triethanolamine, pentaerythrol, sorbitol polyoxyethylene methyl glucoside, and the like.

Examples of fatty acids include higher fatty acids such as stearic acid, palmitic acid, myristic acid, lauric acid, and oleic acid, and examples of fatty acid esters include higher alcohols, higher fatty acid esters, animal and vegetable oils, and isosudearyl. Examples include cholesteryl ester.

Liquid crystal is sensitive to ultraviolet light, and when exposed to ultraviolet light, its structure is destroyed and it deteriorates quickly. Therefore, the application of antioxidants is effective, and as an antioxidant, tocopherol is extremely effective in preventing deterioration over time.

The liquid crystal formulations of the present invention are available in aqueous, oil-based, and surfactant-based types.

The preparation method includes a water-soluble substance having a hydroxyl group, a fatty acid, a fatty acid ester, a higher alcohol, an antioxidant,
After heating and dissolving preservatives, fragrances, water, etc., mixing and cooling, adjust p+ to about 5 to 8 with a small amount of NaOH, and separately heating and dissolving the liquid crystal composition of the present invention. Although it is preferable to mix and disperse the former, they may be heated and dissolved at the same time.

Depending on the method of dispersion, the size of the liquid crystal compound changes and its appearance differs, but care must be taken because if the molecules of the liquid crystal compound are mixed too vigorously and the molecules of the liquid crystal compound are cut, color development will deteriorate.

In addition to its interesting appearance and ability to change color depending on light, temperature, etc., the cosmetics of the present invention have water-retaining properties, moisturizing properties,
It has the great advantage of being safe for the skin.

〔Example〕

The present invention will be specifically explained below with reference to Examples, but the present invention is not limited in any way by these Examples.

All percentages below are expressed in percent by weight.

(Example 1) Water-soluble gel (Example 2) f+f+ gel A Cholesteryl 12-hydroxy 5% Stearate Cholesteryl hebutanoate (3%) Lestaryl hebutanoate 1-3% Cholesteryl oleate 3% Cholesteryl Butyrate 3% Cholesteryl Nonanoe 1-3
% B Carboxy polyvinyl polymer 1.0% glycerin 5.0% 1.3 butylene glycol 5. OX antioxidant (tocopherol) 0.1% fragrance Fit,
0.1% purified water
After heating and dissolving 68.8% B, mixing and cooling,
Na 01-1 was adjusted to I) l-15 to 8.

A was dissolved by heating at 80°C, mixed, and dispersed in B.

This formulation developed color in the temperature range from 0°C to 30°C.

A ]] Restyryl 12-hydroxy 5% stearate] Restyryl heptanoate 5% Cholestaryl heptanoate 1 to 5% B Decaglycerin monostearate 5.0% Glycerin
5.0% propylene glycol
2.0%C liquid paraffin 60
．． 0%olive oil 10.0%
Setanol 1.0% B Purified water 1.8% Preservative (
Methyl paraoxybenzoate) 0.2% B was dissolved by heating,
After mixing, slowly add C and slowly add D to the colander.

After 6, a solution of A dissolved by heating at 80° C. was mixed and dispersed therein.

This compound develops color in the temperature range of 0°C to 30°C.

(Example 3) Transparent facial cleansing foam A Cholesteryl 12-hydroxy 5% stearate] Restyryl heptanony 1-5% Cholesteryl oleate 2.5% Cholesteryl butyrate 1-2.5% B Lauryl dimethyl amino acid betaine 4.0 % myristic acid
12. Ox propylene glycol
3.0% lauric acid jetanolamide 3
．． 0%l~Reethanolamine 102%
C Purified water 4.86%N
-Lauroylmethyltaurine 40y.

After 0.2% sodium preservative (methyl paraoxybenzoate) B is dissolved and mixed, C is added and cooled while stirring.

Δ was dissolved by heating at 80° C., mixed, and dispersed in the BC mixture.

This formulation develops color in the temperature range of 0°C to 30°C.

(Examples 4 to 14) In Example 1, the A component was changed as shown in Table 1 below, and the test was carried out under the same conditions.
1° which developed color at 0° C. (Example 15) A patch test was conducted on the cosmetics of Examples 1 to 14 of the present invention using a panel of 20 people.

(Test method) Closed for 24 hours, safety test on the inner side of the right upper arm (plaster) Torii Pharmaceutical's Panji test adhesive 01 plaster (mini size) (Sample) Apply the cosmetics of Examples 1 to 14 of the present invention with a cotton swab .

(Subjects) 20 women As a result, no abnormality was observed in the coated area.

(Comparative Example 1) In Example 1, Restyril 12 was added to liquid crystal formulation A.
- When the same formulation was used except that hydroxystearate was not included, color development was difficult.

In addition, as a water-holding test 'j'J method, test F31100
While adding purified water to g, mix thoroughly to form a W10 emulsion, and adjust the water-holding capacity by the maximum water addition period that can be emulsified into the W10 type emulsion. When comparing the mixtures of 5% each in Vaseline, the water-holding capacity of the comparative example was 50%, whereas the water-holding capacity of the A component of Example 1 was 150%, and the water-holding capacity was improved. It has been proven that

(Comparative Example 2) In Example 2, liquid crystal formulation △] Restyril 12
When the same formulation was used except that -Hydroxysteare-1 was not added, it was difficult to develop color.

The water-holding ability of both Δ components was tested using the same test method as that of Comparative Example 1.

While the hydration capacity of component A in Comparative Example 1 was 60%,
The water-holding capacity of the A component of Example 2 was 110%, indicating that the water-holding capacity was greatly improved.

(Comparative Examples 3 to 7) Although the items shown in Table 2 do not correspond to the examples like Comparative Examples 1 and 2, cholesteryl 1
It does not contain 2-hydroxystearate 1 and is highly colored, indicating that there is a large amount of cholesteryl ester.
for the purpose of Most of them do not develop color in the human skin humidity range of 0°C to 30°C.

[Effects of the Invention] The cream in which the liquid crystal composition of the present invention is suspended in an oil-based carrier or an aqueous emulsion is a transparent or translucent cosmetic product, so it is similar to human skin. When subjected to appropriate temperatures or other stimuli, the film on the skin's surface reflects light of a wavelength equal to the helical pitch and reflects a rainbow of vivid colors. In the present invention, since cholesteryl 12-hydroxystearate is blended into this liquid crystal system, this color development is ensured, and the water-retaining property and thus the moisturizing property are also greatly improved.

In short, in addition to its interesting appearance, which changes color depending on light and temperature, it has a pearlescent luster and is extremely beautiful.

It is also safe because it does not cause irritation to the skin, unlike when cholesteryl chloride is used.

The present invention is an outstanding invention that provides an excellent cosmetic that has aesthetic luster, moisturizing properties, and safety.

Claims (1)

[Claims] 1. Cholesteryl heptanoate and cholesteryl 12-
A cosmetic containing liquid crystal, which is obtained by dispersing a liquid crystal composition containing hydroxystearate in a transparent or translucent cosmetic. 2. A cosmetic containing a liquid crystal obtained by dispersing a liquid crystal composition containing cholesteryl oleate and cholesteryl 12-hydroxystearate in a transparent or translucent cosmetic. 3. Cholesteryl heptanoate and cholesteryl 12-
Hydroxystearate, cholesteryl heptanoate, cholesteryl oleate, cholesteryl butyrate, cholesteryl laurate, cholesteryl decanate,
A cosmetic containing a liquid crystal, which is obtained by dispersing a liquid crystal composition containing at least one selected from the group consisting of cholesteryl nonanoate in a transparent or translucent cosmetic. 4. A cosmetic containing a liquid crystal obtained by dispersing a liquid crystal composition containing cholesteryl oleate, cholesteryl 12-hydroxystearate, and cholesteryl heptanoate in a transparent or translucent cosmetic.