JPH02297358A - Substrate material for adjusting viscous film - Google Patents

Abstract

PURPOSE:To obtain the proper adhesiveness between an artificial tooth plate and a viscous film adjusting member in use by forming the polymer having the hydrophilic group and hydrophobic group from the solution having a specific concentration. CONSTITUTION:The polymer having the hydrophilic and hydrophobic groups is formed from the solution containing the polymer having the concentration of 0.1-5wt.%. The polymer having the hydrophilic and hydrophobic groups is not specifically limited, and preferably has the molecular weight of 10,000-1,000,000. For example. the vinyl monomer single polymer having the hydrophilic and hydrophobic groups or the copolymer of the vinyl monomer having the hydrophilic group and the vinyl monomer having the hydrophobic group which can copolymerize with the above-described vinyl monomer is preferable. Therefore, the proper adhesion force and exfoliation performance between an artificial tooth plate and an acryl group viscous film adjusting member can be obtained.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a base material for a mucous membrane conditioner. Specifically, the present invention relates to a base material for a mucous membrane conditioning material and a lining method for imparting appropriate adhesion and releasability between the denture base and the mucosal conditioning material by applying it to the denture base in advance.

[Conventional technology]

Currently, in the dental field, materials of various compositions are used as soft lining materials for denture bases. Among them, acrylic mucosa conditioning materials that are used by mixing and gelling a powder component made of an ethyl methacrylate homopolymer or its copolymer with a liquid component made of a plasticizer and ethanol are simple and have appropriate fluidity and elasticity. It is widely used because it has Furthermore, the acrylic mucosa conditioning material has very good adhesion to the denture base, and has the characteristic that it hardly peels off after being placed in the oral cavity.゛[Problems to be solved by the invention] However, the above-mentioned mucosal conditioner has too good adhesion to the denture base, so it is very difficult to easily remove it from the denture base, and it is usually used in dentistry. It is scraped off with a polishing bur, etc. This method has problems in that it produces a strong odor due to food residues adsorbed to the mucous membrane conditioning material in the oral cavity, is time consuming, and is difficult to completely remove.

[Means for solving problems]

The present inventors have conducted extensive research to solve the above problems. As a result, if a solution of a polymer having a hydrophilic group and a hydrophobic group at a specific concentration is applied to the denture base as a base material and then lined with a mucous membrane conditioning material, the denture base and mucosa conditioning material will be separated during use. The inventors have discovered that the mucous membrane conditioning material has appropriate adhesive properties and can be easily removed from the denture base when desired, leading to the completion of the present invention.

That is, the present invention is a base material for a mucous membrane conditioner made of a solution in which a polymer having a hydrophilic group and a hydrophobic group is dissolved at a concentration of 0.1 to 5% by weight.

In the present invention, the polymer is not particularly limited to a polymer having a hydrophilic group and a hydrophobic group, and any known polymer can be used without particular restriction, but generally a polymer having a molecular weight in the range of 10,000 to 1,000,000 is used. suitable. For example, a vinyl monomer homopolymer having both a hydrophilic group and a hydrophobic group, or a copolymer of a vinyl monomer having a hydrophilic group and a vinyl monomer having a hydrophobic group that can be copolymerized with the vinyl monomer is suitable. be. Of course, hydrophilic groups and/or hydrophobic groups may be added after polymerization, but copolymerization is preferable because the balance between hydrophilic and hydrophobic groups can be easily controlled by changing the hinyl monomer ratio. be.

Typical examples of the above-mentioned hydrophilic groups include hydroxyl group, carboxyl group, carboxylic anhydride group, phosphoric acid group,
There are sulfonic acid groups, amino groups, etc.

Among these, hydroxyl groups, carboxyl groups, and carboxylic anhydride groups are preferred in consideration of irritation to the oral mucosa, storage stability, and the like. Examples of vinyl monomers having hydrophilic groups used in copolymerization that are generally preferred include 2-hydroxyethyl methacrylate, acrylic acid-based vinyl monomers such as acrylic acid and methacrylic acid, and maleic acid-based vinyl monomers. acids, unsaturated dibasic carboxylic acid monomers such as fumaric acid, itaconic acid, maleic anhydride, itaconic anhydride, 4-methacryloxyethyl trimellitic acid I.
Examples include aromatic carboxylic acid monomers such as acids, and substituted derivatives obtained by substituting these vinyl monomers with substituents.

Typical hydrophobic groups mentioned above include, for example, aryl groups such as phenyl group and naphthyl group; alkyl groups such as methyl group, ethyl group, propyl group, and butyl group; alkoxy groups such as ethoxy group and butoxy group. ; Acyloxy groups such as an acetyloxy group; Alkoxycarbonyl groups such as an ethoxycarbonyl group and a butoxycarbonyl group. Examples of vinyl monomers having hydrophobic groups that are generally suitable for use in copolymerization include styrene, methylstyrene, vinylnaphthalene, ethylene, propylene, butene, ethyl vinyl ether, and butyl vinyl. Examples include ether, vinyl acetate, methyl methacrylate, ethyl methacrylate, butyl acrylate, and the like.

Moreover, the molar ratio of hydrophilic group/hydrophobic group in the polymer having the above-mentioned hydrophilic group and hydrophobic group is preferably in the range of 0.2 to 5. Typical examples of such polymers include acrylic acid-methyl methacrylate copolymer, maleic anhydride-styrene copolymer and its hydrolyzate, maleic acid-isobutylene copolymer and its hydrolyzate, 2-hydroxyl modified polymers, vinyl alcohol-ethylene copolymers, etc. can be suitably used.

The solvent used in the present invention is not particularly limited and any known solvent can be used as long as it dissolves the above-described polymer, but in general, a solvent that has a low boiling point and can be easily removed by drying afterwards is preferred. Specific examples include volatile organic solvents such as methanol, ethanol, isopropanol, acetone, ethyl acetate, and methylene chloride.

In the present invention, 0.1 of the polymer in the polymer solution
-5% by weight, preferably 0.5-2% by weight. That is, when the concentration of the polymer is lower than 0.1% by weight, when the resulting base material for the mucosa conditioning material is applied to the denture base and the mucosa conditioning material is paved, the mucosa conditioning material may peel off from the denture base. Moreover, if the concentration is higher than 5% by weight, the adhesiveness between the denture base and the mucous membrane conditioning material will be significantly reduced, making it impossible to achieve the object of the present invention.

A method for lining a denture base with a mucosa conditioning material using the base material for a mucosa conditioning material of the present invention involves forming a layer of the base material for a mucosa conditioning material between the denture base and the mucosa conditioning material to be lined. There are no particular limitations as long as it is a method. As a typical lining method, there is a method in which a layer is formed on the lining surface of the denture base using the base material for the mucosa conditioning material of the present invention, and then lining with the mucosa conditioning material is performed.

A common method for forming a layer using the base material for the mucous membrane conditioning material is to apply the base material onto the lining surface of the denture base and dry the solvent. The thickness of such a layer is not particularly limited, but is generally preferably about 0.1 to 5 μm.

Suitable mucous membrane regulating materials to which the base material for mucous membrane regulating materials of the present invention is applied include, for example, acrylic mucosal membranes containing polyethyl methacrylate, polyethyl methacrylate, ethyl methacrylate-methyl methacrylate copolymer, etc. as the lead component. Examples include adjustment materials. As the liquid component of the mucous membrane conditioner, a composition of ethanol and a plasticizer such as dibutyl phthalate, butyl phthalyl butyl glycolate, butyl benzyl phthalate, 2-ethylhexyl phthalate is generally suitable.

[Action and effect]

The feature of the base material for mucous membrane conditioning material of the present invention is that by applying it to the denture base, it simultaneously satisfies the contradictory properties of moderate adhesion and moderate releasability between the denture base and the acrylic mucosa conditioning material. Although the cause of such an effect is not clear, the present inventors speculate as follows. That is, when the base material of the present invention is applied to a denture base and dried to form a layer, the hydrophobic groups of the polymer are, for example, polymethyl methacrylate (hereinafter referred to as PMM), which is the main component of the denture base.
(abbreviated as A) to form an adhesive film, and the surface of the film becomes a hydrophilic surface. Furthermore, because the film is formed by drying a solution with a low concentration, countless pinholes are formed. The mucous membrane conditioning material lined on such a coating adheres to PMMA at the countless pinhole areas, but hardly adheres to the hydrophilic coating area. Therefore, when worn in the oral cavity, where compressive force mainly acts, sufficient adhesive force is developed at the pinhole portion. On the other hand, when a tensile force is applied to remove the coating, the coating easily peels off, and the area of each pinhole attached is very small, making it difficult to remove the mucosa conditioning material without leaving it on the denture base side. It is presumed that it is possible.

From the above, by using the base material for mucosa conditioning material of the present invention, the patient can recover sufficient masticatory power with the denture base lined with the mucosa conditioning material, and the dentist can easily remove it. It has become possible to make mucosa conditioning materials with relatively high adhesive strength, such as acrylic mucosa conditioning materials, easier to use than ever before.

〔Example〕

EXAMPLES Hereinafter, the present invention will be specifically explained with reference to Examples, but the present invention is not limited to these Examples. still,
The mucous membrane conditioning material, denture base range, and peeling force test method shown in this example are as follows.

(1) Mucous membrane conditioning material powder component: polyethyl methacrylate (molecular weight approximately 500,000,
(Average particle size: 40 μm) Liquid components Nibutylphthalyl glycolate 85% by weight, ethanol 15% by weight (2) Resin for denture bases Polymerize heat-polymerized floor resin “Akron” manufactured by Menshisha according to the manufacturer's instructions. A 10 x 100 x 2 crane floor resin board was created.

(3) Peeling force test method After laminating aluminum foil on one side of the above resin floor board so as to cover the surface from the edge to 2011, a frame is made around the entire surface of the above resin floor board, and this frame is A mucous membrane conditioner mixed at a powder/liquid weight ratio of 1:2 was immediately poured into the container to a thickness of 2B, and one side of the floor resin board including the aluminum foil surface was lined with the mucous membrane conditioner. 37 2 minutes after starting mixing
The sample was kept at 100% humidity for 1 hour, then immersed in water at 37°C for 23 hours, and then kept at 23°C for 2 hours. Fold the aluminum foil part of the resin board for the floor 180 degrees,
By tensile testing machine (crosshead speed 0.5
(un/m'in), and the peeling force between the floor resin board and the mucous membrane conditioning material was measured.

In addition, since the mucous membrane conditioning material is an elastic body, the highest value measured was taken as the peeling force. In addition, if this peeling force is 0.2 kg or more, it can be said that the adhesive force is clinically sufficient.

Example 1 Styrene (60 molχ) with a molecular weight of 50,000 - maleic acid (
A 40 mol x) copolymer hydrolyzate was dissolved in ethanol to prepare a 1% by weight solution.

This solution was applied once with a brush to one side of a floor resin board, and after drying with air, the peeling force of the mucous membrane conditioner on the treated surface was measured using the peeling force test method described above. As a result, the peeling force was 0.71 kg, and after peeling, no mucous membrane conditioning material was attached to the floor resin board.

Example 2 Comparative Example 1.2 Peeling force was measured in the same manner as in Example 1 except that the styrene-maleic acid copolymer hydrolyzate and the ethanol solution concentration were changed. The results are shown in Table 1.

Example 3 Comparative Examples 3 to 5 Peeling force was measured in the same manner as in Example 1 except that the polymer and solvent were changed.

The results are shown in Table 2.

Example 4 The compatibility of the entire upper jaw floor became poor after 5 years had passed since installation, so after polishing the surface further, the polymer solution used in Example 1 was applied, and after drying, a mucous membrane conditioning material was poured over the entire surface. It was placed in the oral cavity, muscle formation was performed, and held for 3 minutes. It was removed from the oral cavity and the excess portion was removed with a knife. After using it for a week, I checked and found that there was no peeling.Also, when I pulled it off from the edge,
The mucosa conditioning material could be easily removed without leaving any residue on the floor.

Comparative Example 6 When the same operation as in Example 4 was performed on the same floor without applying the polymer solution, no peeling was observed, but when I tried to peel it off, the mucous membrane conditioning material tore off and remained on the floor, causing the bar to peel off. Had to sand.

Claims (2)

[Claims] (1) Polymer having a hydrophilic group and a hydrophobic group from 0.1 to
A base material for a mucous membrane conditioner consisting of a solution dissolved at a concentration of 5% by weight. (2) When lining a denture base with a mucous membrane conditioning material, 0.0% of a polymer having a hydrophilic group and a hydrophobic group is applied to the lining surface of the denture base.
A method for lining a denture base, comprising forming a layer of a base material for a mucous membrane conditioner made of a solution dissolved at a concentration of 1 to 5% by weight.