JPH0262811A - Skin cosmetic - Google Patents

Abstract

PURPOSE:To provide a skin cosmetic containing a far IR light-irradiating ceramics and a succinate salt, accelerating the moisture-holding function of a skin, retaining or recovering the skin in a healthy state and exhibiting an excellent skin-beautifying effect. CONSTITUTION:A far IR light-irradiating ceramic powder having an electromagnetic wave-irradiation percent of >=80% based on the electromagnetic irradiation amount of a black body at the same temperature in a wavelength range of 6-20mum and a succinate salt as active ingredients are suitably compounded with a dyestuff, perfume, antiseptic, surfactant, antioxidizing agent, oily base, etc., by a conventional method to provided the objective cosmetic. The contents of the far IR light-irradiating ceramic powder and the succinate salt are 0.01-20wt.% and 0.1-5wt.%, respectively. The cosmetic can be applied to calamine lotions, creams, milky lotions, make-up bases, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION (Industrial Application Field) The present invention relates to a skin cosmetic that can enhance the moisture retention function of the skin and contains far-infrared emitting ceramics and a succinic acid salt.

(Prior art) In order to maintain healthy skin, hydrophilic skin moisturizers and oily skin softeners that provide appropriate moisture and oil to the skin have traditionally been blended into skin cosmetics. There is.

Skin warming agents include glycerin, propylene glycol,
Polyethylene glycol, lolidone carboxylate, etc. are used, but these may absorb water from the stratum corneum, the outermost layer of the skin, and may actually cause the skin to lose one member of its moisture. Furthermore, skin cosmetics that contain a large amount of such substances are not always satisfactory, as they give an uncomfortable feeling such as stickiness.

In addition, liquid paraffin, petrolatum, olive oil, squalane, lanolin, synthetic ester oil, etc. are used as skin softeners, but these are also included in skin cosmetics to the extent that they sufficiently prevent water evaporation from the epidermis. When exposed to skin, it has disadvantages such as inhibiting the normal metabolism of the skin.

(Disclosure of the Invention) In view of the above-mentioned drawbacks of skin moisturizers and emollients, the present inventors have determined that they rely only on the physical action of these ingredients to replenish moisture to the epidermis or prevent water evaporation from the epidermis. The aim is to provide skin cosmetics that maintain or repair the skin in a healthy state by enhancing the skin's inherent moisture retention function, rather than denucleation. They discovered this and completed the present invention.

Moisture in the skin constantly moves from the inside of the skin to the outer layer, along a gradient of water content that decreases as it goes from the dermis to the basal cell layer of the epidermis, then to the stratum corneum, and then transpires to the outside through the stratum corneum. However, this water evaporation is mainly controlled by a protective function (barrier function) consisting of a dense cellular U weave extending from the lamellar granules at the top of the granular layer to the stratum corneum. Wat
er Loss) value (hereinafter referred to as TWI value)] is in the range of 0.2 to 0.3 mg/cm''/hr on the skin surface of the forearm in a normal state of healthy skin, for example.
It is usually maintained at about 0.25 mg/cm2/hr or less.

On the other hand, in the case of dry skin that is normally observed (dry skin) or dry skin that occurs in aging skin, the TWL value shows the upper limit of the above range or a value higher than that depending on the degree of dry skin, and the It is recognized that the water retention function has decreased. This is because, in the case of dry skin, the normal control limit of the protective function of the stratum corneum is exceeded, or the protective function of the stratum corneum is weakened.

Therefore, if we can densify the structure of the stratum corneum and lamellar granules and activate their defense function, this will enhance the moisture retention function of the skin, maintain the skin in a healthy state, and further reduce dry skin. Improvement or repair is possible.

Therefore, as a result of intensive research into the effects of succinic acid salts on human skin, the present inventors found that succinic acid salts activate cellular respiration in the skin, leading to tissue formation from the lamellar granules at the top of the granular layer to the stratum corneum. Components in skin fat that are more densified than normal are activated by far infrared rays, strengthening densified skin cells, increasing moisture retention, promoting keratin turnover, and reducing dry skin. The present invention has been found to have a skin beautifying effect that improves the skin and prevents aging by maintaining the skin in a healthy state and imparting moisture (moistness), flexibility (smoothness), elasticity and luster to the skin. It was completed. In the case of the skin cosmetics of the present invention, unlike conventional skin cosmetics, there is no need to incorporate large amounts of the above-mentioned skin moisturizers and skin softeners, and there is no risk of interfering with the normal physiological functions of the skin.

(Objective of the Invention) The object of the present invention is to provide a skin cosmetic that maintains or repairs the skin in a healthy state by enhancing the skin's inherent moisture retention function and has an excellent skin beautifying effect. There is something to do.

(Structure of the Invention) The present invention provides a far-infrared emitting ceramic powder having an electromagnetic radiation percentage of 80% or more based on the electromagnetic radiation amount of a black body at the same temperature in the wavelength range of 6 to 20 μm; A skin cosmetic containing an acid salt.

(Blackbody explanation of the structure) The electromagnetic radiation percentage in the present invention is the relative radiation intensity of a sample at the same temperature, when the energy radiation intensity of an ideal black body at a constant temperature follows Blank's law is taken as 100%. It is energy emissivity. The electromagnetic radiation percentage of a sample does not vary depending on temperature, but the wavelength of the sample varies from 6 μm to 2 μm in the temperature range of 30 to 70°C depending on body temperature.
A material with a radiation percentage of 0 μm electromagnetic waves of 80% or more is used.

The far-infrared emissive ceramic/7x powder used in the present invention is made of known magnesium oxide, aluminum oxide, zirconium oxide, silicon oxide, or metal carbonate, viscosity t'pA, etc., by the following chemical reaction. It is obtained by mixing sufficiently uniformly at the ratio shown in the formula (chemical M theoretical ratio), firing at 1000°C or higher, and pulverizing. For example, cozy light
(2Mg0・2A1zO3・5SiOz) is talc (
3Mg0・4SiOz・H2O) and chi! Lin (A
It is obtained by mixing ffizO*・2SiOz・2HtO) and magnesite (MgC○,), firing at 1400°C, and pulverizing the mixture. The chemical reaction formula is as follows.

3Mg0・4 S + Ot・Hz O+ 8
(A 1t O: +-2S io, ・2H,0)
+5MgC0* →4(2Mg0・2Al103 ・
55i0. )+17 H20+ 5 COz Zircon (Z r S I Oa ) is produced by mixing zirconia (ZrOz) and silica (Sift), firing,
Obtained by grinding. In addition, a naturally occurring zircon sample is measured using an FT-IR spectrometer IF5-113V manufactured by Ruker under the following conditions.

Detector: DTGS Attached equipment: Attached equipment reference sample for emission spectrum measurement
:Blackbody measurement temperature: 60℃ Measurement wavelength: 6 to 20μm Note that the above emissivity does not change depending on the temperature, so the feel and effectiveness of the powder measuring body at 60℃, which is easier to measure than near skin temperature. to conidirite, 0.01 to 20 μm. 20. If it is larger than 0.01 μm, it will cause a strange feeling on the skin, and if it is smaller than 0.01 μm, it has a strong catalytic effect that degrades the oil base in cosmetics, and the emissivity curves are compared as shown in Figures 1 and 2. [Method for measuring spectral infrared emissivity curve] A range of 0.01 to 20% by weight (hereinafter abbreviated as wt%) is suitable. If the content is less than 0.01 Wt%, the effect will not be sufficiently achieved, and if it exceeds 20wt%, no improvement in the effect commensurate with the increase can be expected.

The succinic acid salt used in the present invention is a monosalt or di-salt consisting of succinic acid and a base, such as potassium salt,
Examples include alkali metal salts such as sodium salts, basic amino acid salts such as lysine salts, ornithine salts, and arginine salts, and alkanolamine salts such as monoethanolamine salts and triethanolamine salts. Further, as the salt of succinic acid, a salt of succinic acid and a basic amino acid salt is particularly suitable in terms of its effects as described later.

The content of the succinic acid salt is preferably in the range of 0.1 to 5.0 wt% based on the total amount of skin cosmetic #Oka-Nishikigyu. If the content is less than 0.1 wt%, the effect will not be sufficiently achieved, while if the content exceeds s, o wt%, no improvement in the effect commensurate with the increase can be expected.

The skin cosmetics of the present invention can be applied to, for example, calamine lotions, creams, milky lotions, makeup bases, and the like.

In addition to the above-mentioned ingredients, the skin cosmetics of the present invention may contain pigments, fragrances, preservatives, surfactants, antioxidants, oil bases, etc. as appropriate within the scope of achieving the purpose of the present invention. can.

(Example) Hereinafter, the present invention will be explained in detail based on Examples and Test Examples.

The methods for measuring or evaluating the TWL value, rate of change in TWL value, stratum corneum turnover rate, and exfoliation properties of corneocytes are shown below.

+1) T W L (A method was used to measure the humidity change within a certain period of time in the air above the directly sealed skin surface using electrical resistance.

That is, the test subject's skin surface is sealed in a measurement cell, forced dry air is vented into the cell to sufficiently replace the inside of the cell with dry air, and then the ventilation of dry air is stopped and the cell is closed at that point. Determine the relative humidity RHs (%) within the cell, then let it stand for 10 minutes and then increase the relative temperature RH inside the cell again. (%),
The TWL value was calculated from the temperature change at this time using the following formula.

SXI (J (1) However, Dt: Density of saturated water vapor in air at measurement temperature (t °C) (mg/1) ■: Volume of cell (1) S: Measurement area (cm”) +21TWL value change rate The TWL values before and after applying the sample (skin cosmetic) to the skin were determined, and the rate of change was calculated using the following formula to evaluate the TWL hypofreezing effect (moisture retention function enhancement effect).

TWI before sample (skin cosmetic) application, value: TW
L.

TWL value after application of sample (skin cosmetic): TWL
A (3) Method for measuring the turnover rate of the stratum corneum 5% by weight of the fluorescent dye danzyl chloride in white petrolatum
A blended ointment is prepared and applied as an occlusive patch to the skin of the subject's forearm for 24 hours to allow danzyl chloride to penetrate and bind to the stratum corneum. Thereafter, the test sample was applied to the same area twice a day (morning and evening), and the fluorescence of danzyl chloride was checked every day.The number of days until the fluorescence disappeared was defined as the turnover rate of the skin stratum corneum. Note that the normal turnover rate of the stratum corneum of the skin is 14 to 16 days, but in aged skin, the turnover rate increases to around 18 days. On the other hand, if the anti-aging effect appears, the time will be shortened to around 12 days.

(4) Peeling characteristics of keratinocytes A Scotch tape or Chiban mending tape) was applied to the skin, and this was peeled off to allow the keratinocytes on the skin surface to adhere to the tape.The state of the keratinocytes was then measured using scanning electronics. After detailed observation using a microscope, the exfoliation characteristics of the corneocytes were classified based on the criteria shown in Table 1, and their indices were determined.

Table 1 Criteria for Judging the Peeling Properties of Corneocytes The peeling properties of corneocytes serve as an index for determining the structural properties of the stratum corneum, and in general, in dry skin and aging skin, intercellular bonds are It has been confirmed that the index is high because the force is weak and the density of the structure is also low.

Examples 1 to 3, Comparative Example 1 (Skin Cream) (1)
Mi raw material composition Blend amount (wt%) A) Ingredients shown in Table 2 Shooter IB shown in Table 2) Liquid paraffin 15.0 Beeswax
5.0 stearic acid
3.0 Sorbitan Sesquioleate 2.0
Setanol 2. OP,○,E
Sorbitan monooleate (20E, O,) 5. O C) Glycerin 5.0 Methyl oxybenzoate 0.1 Monosodium succinate 0.5 Purified water Total volume 1 O
Amount to make 0wt% Table 2 (2) Preparation method Component A) is uniformly dispersed in a mixture of component C) heated and dissolved at 80°C, and component B) heated and dissolved at 80°C is added thereto and stirred. Each skin cream was prepared by cooling the mixture to 30°C.

(3) Test Results Test Example 1 When the skin creams of the present invention of Examples 1 to 3 and the skin cream of Comparative Example 1 were applied, their effects on TWL values and keratin cell exfoliation properties were investigated.

+11 Test method 60 healthy normal skin test subjects (age 20-25)
20 subjects (20 to 25 years old) were divided into 3 groups (groups A, C, and E), and 60 subjects (20 to 25 years old) with normal dry skin were divided into 3 groups (groups A, C, and E). Divided into groups (B, D and F groups).

Prior to the test, T W L of the skin surface of the left and right forearms of all test subjects.
(a was measured, and the average value was calculated for each group.Next, the skin cream of Comparative Example 1 was applied to the skin surface of the test subject's forearm, the left forearm for all test subjects, and the skin cream of Comparative Example 1 was applied to the right forearm. is 1.
For each group, Example 1 was used for groups A and B. Groups C and D received the skin cream of Example 2, and groups E and F received the skin cream of Example 3 twice a day (morning and evening).
The cream was applied for a month, and on the next day of application, the TWL values of the skin surface areas of the left and right forearms to which the cream had been applied were measured for all test subjects, and the keratin cell exfoliation properties were evaluated.

After the application test, a doctor diagnosed no abnormalities in the skin or physical condition of the forearm of any of the test subjects.

(2) Results: TWL values before and after application of skin cream.
The TWL value change rate calculated from the L value and the index of keratinocyte exfoliation characteristics (both values are the average values of 20 people in each group) were
Shown in the table.

From the results shown in Table 3, Example 1 of the present invention is as follows.
The effects of skin creams 2 and 3 were observed.

■ In the skin of healthy fil in Groups A, C, and E, the moisture retention function of the skin is originally maintained in a normal state, so the skin cream of the present invention (Examples 1.2 and 3) was applied. Although the effect is difficult to become apparent, a slight improvement is still observed compared to Comparative Example 1.

■ For dry skin in Groups B, D, and F, the skin surface of the right forearm to which the skin cream of the present invention (Examples 1.2 and 3) was applied was applied, and the skin surface of the left forearm (skin of Comparative Example 1) was applied. A significant improvement in the TWL value was observed compared to the cream), and the value was equal to or approaching that of healthy skin. When comparing the creams of the present invention, Example 3 had the highest moisture retention function improvement effect, followed by Example 2.1. Furthermore, similar results were obtained in the corneum cell peeling test.

It shows the effect of maintaining normal skin, and also has B, D and eF
It is clear that this group has the effect of resembling healthy skin.

From these results, the far-infrared emitting ceramics and succinic acid salt contained in the skin creams of Examples 1.2 and 3 of the present invention effectively act on epidermal cells and increase the intercellular bonding ability of the stratum corneum. It can be seen that it improves the skin's structure, densifies it, and enhances the skin's moisture retention function, and that it is highly safe and does not interfere with the physiological functions of healthy skin.

Test Example 2 The effects of the skin cream of the present invention in Example 3 and the skin cream of Comparative Example 1 on the TWL value and stratum corneum turnover rate of healthy skin and aged dry skin were investigated.

+11 Test method Newly, 20 subjects with normal healthy skin (women aged 20 to 25 years old) were added to the G group, and 20 subjects with dry skin due to aging were added to the H group (females aged 20 to 25 years old). For a total of 40 women (50 to 60 years old), the TWL values on the skin surface of the left and right forearms were measured in advance, and ointment containing danzyl chloride was applied as an occluded patch on the left and right forearms for 24 hours. next,
The skin cream of Comparative Example 1 was applied to the skin surface of the left forearm of all subjects in Groups G and H, and the skin cream of Example 1 was applied to the skin surface of the right forearm.
'skin cream twice a day (morning and evening)! The solution was applied for one month and the fluorescence was checked every day. On the day after the final application, the TWL values of the skin surface areas of the left and right forearms to which the cream was applied were measured for all test subjects.

After the completion of the application test, no abnormality was observed in the skin of the forearm or physical condition of all the test subjects according to the results of diagnosis by a doctor.

(2) Results TWL values before and after skin cream application (average value of 20 people in each group), TWL calculated from these TWL values
Table 4 shows the value change rate and the stratum corneum turnover rate (average values for 20 people in each group).

From the results shown in Table 4, the effects of the skin cream of Example 3 of the present invention were recognized as follows.

■ In the healthy, conventional skin of the G group, the functional status of the skin was maintained normally, so the skin cream of the present invention (Example 3) did not increase the turnover rate of the stratum corneum. I couldn't.

Further, for T W 111M, the same results as in Test Example 1 were obtained.

■ In the aging dry skin of group H, the skin surface of the right forearm to which the skin cream of the present invention (Example 3) was applied was compared to the skin surface of the left forearm (to which the skin cream of Comparative Example 1 was applied). The turnover rate of the stratum corneum is ridiculous! ! (shortening) was observed, and the value approached that of normal skin.

Regarding the TWL value, application of the cream of the present invention (Example 3) showed a significant improvement (reduction in the TWL value), similar to what was observed in normal dry skin in Test Example I, and it was found that the value was equivalent to that of a normal person. Or something close to that value.

That is, it can be said that the skin cream of Example 1 of the present invention brings the turnover rate of the stratum corneum of aged dry skin closer to that of healthy skin, and enhances the water retention function.

Test Example 3 1 Comparative Example [and 30 test subjects (women aged 26 to 34 years old) who complained of dry skin when using the skin creams of Examples 1 to 3]
It was applied twice a day (morning and evening) for a continuous month. Diagnosis by a doctor revealed no abnormalities in the skin or physical condition of all test subjects.

Moisture (moist feeling) on the skin after applying the cream,
Table 5 shows the results of a survey on all test subjects regarding the effect of imparting flexibility (smooth feel), elasticity, and gloss.

The skin creams of Examples 1 to 3 have significantly better effects than the skin creams of Examples 1 to 3.

Table Examples 4 to 5, Comparative Example 2 (Skin milk) (1) Composition Raw material composition Amount (wt%) A) Zircon
2. OB) Liquid paraffin 10.0 cetanol
2.0 cholesterin
1.0 Sorbitan monoorny 1-0.
5C) Sodium cetyl sulfate 0.8 No. 6
Ingredients shown in Table 6 M-end ice making shown in Table 6 Amount to make the total amount 100 wt% (2) Adjustment method The same procedure as in Example 1 is carried out.

Table 6 Test Example 4 Thirty test subjects (females aged 26 to 34) complained of dry skin after receiving the skin milks of Comparative Example 2 and Examples 4 and 5.
It was applied twice a day (morning and evening) for a continuous month. Diagnosis by a doctor revealed no abnormalities in the skin or physical condition of all test subjects.

Next, we investigated the effects of applying skin milk on the skin in terms of moisture (moist feeling), flexibility (smoothness), elasticity, and shine on the skin, and the results are clear from the results in Table 7. As such, Examples 4 to 4 of the present invention
All of the skin milks of Example 5 show better results than Comparative Example 2, but especially the skin milk of Example 5 has a remarkable skin improvement effect. (Effects of the Invention) As described above, the present invention Skin cosmetics maintain or repair the skin in a healthy state by enhancing the skin's inherent moisture retention function, giving the skin moisture, flexibility, elasticity, and luster, and providing excellent skin care. This clearly provides a skin cosmetic that has skin beautifying effects.

[Brief explanation of the drawing]

Figures 1 to 4 are spectral infrared emissivity curves of zircon, cordierite, titanium oxide, and talc, respectively. Figure 1 5 Bed length (P^) -J, -gL (,^A/?Ln

Claims (1)

[Claims] 1) Contains far-infrared emissive ceramic powder and succinic acid salt that has an electromagnetic radiation percentage of 80% or more in the wavelength range of 6 to 20 μm, based on the electromagnetic radiation amount of a black body at the same temperature. skin cosmetics.