JPH0334812B2 - - Google Patents
Info
- Publication number
- JPH0334812B2 JPH0334812B2 JP58206359A JP20635983A JPH0334812B2 JP H0334812 B2 JPH0334812 B2 JP H0334812B2 JP 58206359 A JP58206359 A JP 58206359A JP 20635983 A JP20635983 A JP 20635983A JP H0334812 B2 JPH0334812 B2 JP H0334812B2
- Authority
- JP
- Japan
- Prior art keywords
- probe
- temperature
- living body
- antenna coil
- piezoelectric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000523 sample Substances 0.000 claims description 23
- 238000000034 method Methods 0.000 claims description 11
- 238000009529 body temperature measurement Methods 0.000 claims description 7
- 238000010521 absorption reaction Methods 0.000 claims description 3
- 238000001727 in vivo Methods 0.000 claims description 3
- 239000013078 crystal Substances 0.000 description 9
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 2
- 238000013480 data collection Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000009217 hyperthermia therapy Methods 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 208000037819 metastatic cancer Diseases 0.000 description 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000015 thermotherapy Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K7/00—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements
- G01K7/32—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using change of resonant frequency of a crystal
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K1/00—Details of thermometers not specially adapted for particular types of thermometer
- G01K1/02—Means for indicating or recording specially adapted for thermometers
- G01K1/026—Means for indicating or recording specially adapted for thermometers arrangements for monitoring a plurality of temperatures, e.g. by multiplexing
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Temperature Or Quantity Of Heat (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Description
【発明の詳細な説明】
本発明は生体内温度測定用プローブ、殊に生体
内の温度をその生体内外を結合するケーブルを使
用することなく測定する為のプローブに関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a probe for measuring temperature inside a living body, and particularly to a probe for measuring temperature inside a living body without using a cable connecting the inside and outside of the living body.
従来生物学、医学上の研究或は特にガンの治療
等を目的として生体内各部の温度を測定する為長
期間生体内に埋込んだ無電源プローブと生体外の
測定器との間を有線にて接続することなしに測温
する方法が提案されている。 Traditionally, in order to measure the temperature of various parts of a living body for the purpose of biological or medical research or especially cancer treatment, a wired connection is used between an unpowered probe implanted in a living body for a long period of time and a measuring device outside the living body. A method has been proposed to measure temperature without having to connect the device.
上述の如き測温方法としてはアンテナ・コイル
に水晶振動子を接続したプローブを生体内の所望
の位置に外科的に埋込むか或はこれを消化器内に
流すと共に生体外から所要周波数の電磁エネルギ
を放射し前記アンテナ・コイルを介して前記水晶
振動子に与えこれが共振する際のエネルギ吸収を
観測するか或は前記電磁エネルギの放射を中止し
た直後に於ける前記水晶振動子の残響を前記アン
テナ・コイルを介して受信する手法がある。 The above-mentioned temperature measurement method involves surgically implanting a probe with a crystal oscillator connected to an antenna coil at a desired location within the body, or passing it into the digestive tract and injecting electromagnetic waves at the desired frequency from outside the body. Either radiate energy and apply it to the crystal oscillator via the antenna coil and observe the energy absorption when it resonates, or measure the reverberation of the crystal oscillator immediately after stopping the electromagnetic energy emission. There is a method of receiving through an antenna coil.
しかしながら上記いずれの方法に於いても使用
するプローブは特定の温度−周波数特性を有する
単一の圧電振動子を備えたものであつた為、１個
のプローブにて測温し得る点は１点だけであつ
て、殊に体内に広く転移したガンの温熱治療を行
なわんとする場合多数のプローブを埋設する必要
があり極めてわずらわしいのみならず患者に与え
る苦痛も多大なものとなるという欠陥があつた。 However, in any of the above methods, the probe used was equipped with a single piezoelectric vibrator with specific temperature-frequency characteristics, so the temperature could only be measured at one point with one probe. However, when performing thermotherapy for cancer that has spread widely within the body, it is necessary to implant a large number of probes, which is not only extremely cumbersome but also causes great pain to the patient. Ta.
本発明は上述の如き従来のプローブの欠陥を除
去する為になされたものであつて、特定温度に於
ける共振周波数が夫々異なる複数の圧電振動子を
前記アンテナ・コイルに並列に接続した生体内温
度測定用プローブを提供することを目的とする。 The present invention has been made in order to eliminate the defects of the conventional probe as described above, and is an in-vivo probe in which a plurality of piezoelectric vibrators each having a different resonance frequency at a specific temperature are connected in parallel to the antenna coil. The purpose of the present invention is to provide a temperature measurement probe.
以下、本発明をその原理と実施例とを示す図面
によつて詳細に説明する。 Hereinafter, the present invention will be explained in detail with reference to drawings showing its principle and embodiments.
第１図は本発明に係るプローブの構成を示す回
路図である。 FIG. 1 is a circuit diagram showing the configuration of a probe according to the present invention.
即ち、X1乃至X5は特定の温度、例えば36℃に
於ける共振周波数が夫々10000MHz、10010MHz、
…、10040MHzの＋5°Yカツト水晶振動子であり
これらを夫々アンテナ・コイルＬに並列に接続し
たものである。 That is, X 1 to X 5 have resonance frequencies of 10,000 MHz, 10,010 MHz, respectively at a specific temperature, for example, 36°C.
..., 10040MHz +5°Y-cut crystal oscillators, each of which is connected in parallel to the antenna coil L.
上述の如きカツト・アングルの水晶振動子は温
度が１℃変化するとその共振周波数は第２図に示
す如くほゞ1KHz変動するものである。 When the temperature of the cut-angle crystal resonator described above changes by 1° C., its resonant frequency changes by about 1 KHz as shown in FIG.
そこで上記第１図に示す如く構成したプローブ
を生体内所望の位置に埋込み、生体外から所定周
波数、例えば10012MHzの電磁波を前記アンテ
ナ・コイルＬに放射したところ当該周波数に於け
るエネルギ吸収が詳細説明を省略する体外測定器
を構成するエネルギ検出器によつて観測されたと
仮定すればこれは前記第２図から明らかな如く前
記水晶振動子X2の周辺温度が38℃であることを
検知したことを意味することが理解されよう。 Therefore, a probe configured as shown in Fig. 1 above was implanted at a desired position in a living body, and electromagnetic waves of a predetermined frequency, for example, 10012 MHz, were radiated from outside the living body to the antenna coil L. The energy absorption at that frequency was explained in detail. Assuming that the observation was made by an energy detector constituting an external measuring device omitting , this means that the ambient temperature of the crystal oscillator X 2 was detected to be 38°C, as is clear from FIG. be understood to mean.
尚、この際、前記水晶振動子X1が48℃或はX3
が28℃であることをも意味するが、例えば人体の
組織が耐え得る温度のレンジを参照すればこれら
の可能性のあり得ないことは自明であろう。 At this time, the temperature of the crystal oscillator X 1 is 48℃ or X 3
This also means that the temperature is 28°C, but if we refer to the temperature range that human tissue can withstand, it will be obvious that these possibilities are impossible.
又、圧電振動子の残響を利用する測温法に本発
明のプローブを適用すれば同様に外部から与えら
れた所定周波数に共振した振動子の減衰振動が観
測されることも明らかであろう。 It is also clear that if the probe of the present invention is applied to a temperature measurement method that utilizes the reverberation of a piezoelectric vibrator, damped vibrations of the vibrator resonating at a predetermined frequency given from the outside will be similarly observed.
ところで本発明に係るプローブはこれを外科的
に生体内に埋込むものにあつては第３図に示す如
く生体組織となじみがよくしかも比較的フレキシ
ブルなプラスチツクスＣで包囲する必要があり、
斯くすることによつて比較的自由に所望の測温点
に各圧電振動子を配置することが可能となるもの
である。 By the way, if the probe according to the present invention is to be surgically implanted in a living body, it must be surrounded by plastic C, which is compatible with living tissue and relatively flexible, as shown in FIG.
By doing so, it becomes possible to relatively freely arrange each piezoelectric vibrator at a desired temperature measurement point.
一方、前記アンテナ・コイルＬへの電磁波放射
の方法としては各種周波数の電磁エネルギを順次
与える方法と同時に与える方法とのいずれを用い
てもよく前者によれば装置は簡単安価となり後者
によれば装置は複雑高価となるが短時間に多点の
温度測定が可能となろう。 On the other hand, as a method for radiating electromagnetic waves to the antenna coil L, either a method of sequentially applying electromagnetic energy of various frequencies or a method of simultaneously applying electromagnetic energy may be used.The former method makes the device simple and inexpensive; the latter method makes the device Although it is complicated and expensive, it will enable temperature measurement at multiple points in a short time.
尚、上述の実施例に於いては圧電振動子を水晶
振動子に又その数を５個としたが本発明がこれら
に限定される必然性は全くなく振動子の種類、数
を用途によつて自由に選択し得ることはいうまで
もない。 In the above embodiment, the piezoelectric vibrator is a crystal vibrator, and the number of crystal vibrators is five, but the present invention is not necessarily limited to these, and the type and number of vibrators can be changed depending on the application. It goes without saying that you can choose freely.
又、プローブの形状も必ずしも直線的である必
要はなく用途に応じて前記アンテナ・コイルを中
心に放射状に或は分枝する如く圧電振動子を配置
するものであつてもよい。 Further, the shape of the probe does not necessarily have to be linear, and the piezoelectric vibrators may be arranged radially or branchingly around the antenna coil depending on the purpose.
更に前記圧電振動子列と前記アンテナ・コイル
とを分離結合自在の構造とし温度センサたる圧電
振動子列を生体内深部に、前記アンテナ・コイル
を生体表面近傍に配置して感度を向上し、前記両
者を結線用アタツチメントを介して接続するよう
にしてもよい。 Furthermore, the piezoelectric vibrator array and the antenna coil are structured so that they can be separated and coupled, and the piezoelectric vibrator array serving as a temperature sensor is placed deep within the body, and the antenna coil is placed near the biological surface to improve sensitivity. The two may be connected via a wiring attachment.
本発明に係る生体内温度測定用プローブは以上
説明した如く構成し且つ機能するものであるから
極めて簡単安価に構成し得ると共に単一のプロー
ブによつて生体内の多数のポイントの温度を単時
間の内に測定することが可能となるので生物学或
は医学上の研究を行う上でデータ採取能率を向上
するのみならず殊にガンの温熱療法を行う際の温
度監視システムに適用するならば体内各所に転移
したガン組織に対し少数回の外科手術によつてプ
ローブを配置することが可能となるので患者に与
える苦痛を極限し、同時に多数の転移ガンを治療
する上で著しい効果を発揮するものである。 Since the in-vivo temperature measuring probe according to the present invention is constructed and functions as described above, it can be constructed extremely easily and at low cost, and can measure the temperature of many points within the living body in a single time using a single probe. This not only improves data collection efficiency in biological or medical research, but can also be applied to temperature monitoring systems used in hyperthermia therapy for cancer. It is possible to place probes in cancerous tissues that have metastasized to various parts of the body through a small number of surgical operations, which minimizes the pain caused to patients and is extremely effective in treating multiple metastatic cancers at the same time. It is something.
第１図は本発明に係るプローブの基本構成を示
す回路図、第２図はその測温原理を説明する図、
第３図は本発明に係るプローブの一実施例を示す
断面図である。
X1乃至Xn……圧電振動子、Ｌ……アンテナ・
コイル。
FIG. 1 is a circuit diagram showing the basic configuration of the probe according to the present invention, FIG. 2 is a diagram explaining its temperature measurement principle,
FIG. 3 is a sectional view showing an embodiment of the probe according to the present invention. X1 to Xn...Piezoelectric vibrator, L...Antenna/
coil.
Claims (1)
ローブを生体内に埋込み前記生体外から所定周波
数の電磁エネルギを前記アンテナ・コイルを介し
て前記圧電振動に与えこれが共振する際の前記電
磁エネルギ吸収を観測するか或は前記電磁エネル
ギの放射を中止した直後に於ける残響を観測する
生体内温度測定法に於いて、前記プローブの圧電
振動子を所定の温度に於ける共振周波数が夫々異
なる複数個の圧電振動子とすると共にこれらを前
記アンテナ・コイルに並列に接続したことを特徴
とする生体内温度測定用プローブ。1. Implanting a probe in which a piezoelectric vibrator is connected to an antenna coil in a living body, applying electromagnetic energy of a predetermined frequency from outside the living body to the piezoelectric vibration through the antenna coil, and observing the electromagnetic energy absorption when the piezoelectric vibration resonates. Alternatively, in an in-vivo temperature measurement method in which reverberation is observed immediately after the electromagnetic energy emission is stopped, the piezoelectric vibrator of the probe is connected to a plurality of piezoelectric vibrators each having a different resonance frequency at a predetermined temperature. A probe for measuring temperature in a living body, characterized in that it is a piezoelectric vibrator and is connected in parallel to the antenna coil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58206359A JPS6098323A (en) | 1983-11-02 | 1983-11-02 | Probe for measuring temperature in living body |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58206359A JPS6098323A (en) | 1983-11-02 | 1983-11-02 | Probe for measuring temperature in living body |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6098323A JPS6098323A (en) | 1985-06-01 |
| JPH0334812B2 true JPH0334812B2 (en) | 1991-05-24 |
Family
ID=16522011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58206359A Granted JPS6098323A (en) | 1983-11-02 | 1983-11-02 | Probe for measuring temperature in living body |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6098323A (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005024636B3 (en) * | 2005-05-30 | 2006-10-19 | Siemens Ag | Temperature sensor has resonant frequency of resonant circuit dependent on resonant frequency of piezoacoustic resonator; piezoelectric material of piezoelectric layer of piezoacoustic resonator contains langasit |
| JP2008256519A (en) * | 2007-04-04 | 2008-10-23 | Tokyo Denpa Co Ltd | Multipoint crystal temperature measurement apparatus |
| JP5639877B2 (en) * | 2010-12-24 | 2014-12-10 | 株式会社フルヤ金属 | Temperature sensor |
| JP2012189336A (en) * | 2011-03-08 | 2012-10-04 | Furuya Kinzoku:Kk | Temperature measurement device |
-
1983
- 1983-11-02 JP JP58206359A patent/JPS6098323A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6098323A (en) | 1985-06-01 |
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