JPH0368705B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION A. Field of Industrial Application The present invention relates to a chamber used in an artificial kidney blood circuit, an artificial liver blood circuit, and other blood circuits.

B. Prior Art As shown in Figure 9, the blood circuit for an artificial kidney consists of an arterial circuit 1 that extracts blood from a patient's vein and leads it to a dialysis machine, and a vein that sends the dialyzed blood through the dialysis machine to the patient's vein. The circuit 2 consists of a circuit 2, and when used, normally an arterial chamber main body 3 and a venous chamber main body 4 are connected to a dialysis machine, a blood pump, or a heparin infusion machine by means of hanging devices 5 and 6 such as hanging rings attached to them. , a state in which blood inflow tubes 7, 8 and blood outflow tubes 9, 10, which are suspended above the patient and connected to each chamber body 3, 4, hang down from each chamber body 3, 4. The blood inflow tube 7 is connected to the needle 1.
1 to the patient's vein, a blood outflow tube 9 connected to the inlet of the dialysis machine via a connector 12, a blood inflow tube 8 connected to the outlet of the dialysis machine via a connector 13, and a blood outflow tube 9 connected to the outlet of the dialysis machine via a connector 13. 10 is connected to the patient's vein via needle 14.

In the conventional artificial kidney blood circuit described above, blood inflow tubes are connected to the ends of the arterial chamber main body and the venous chamber main body that become the upper ends when they are suspended (hereinafter referred to as the upper end), and the opposite end (hereinafter referred to as the lower end)
A blood outflow tube was connected to each.

C. Problems to be Solved by the Invention The above-mentioned conventional blood circuit for an engineered kidney had the following problems.

The tubes 7, 8 connected to the upper ends of each chamber body 3, 4 are formed with U-turn portions 15, 16 near the upper ends of each chamber body 3, 4 in the direction of pulling them down into each chamber body 3, 4. When force is applied, U-turn portion 15,
Care must always be taken to ensure that the U-turn portions 15 and 16 do not bend, as there is a risk that the tube wall of tube 16 may bend and cut off the flow of blood.

Inside each chamber main body 3, 4, after blood falls through the air above the chamber,
7 and 18, air bubbles are likely to get mixed into the blood and bubbles can easily form on the upstream side of the filter screens 17 and 18, and the air bubbles are pushed downstream from the meshes of the filter screens 17 and 18. net 17,
It is easy to mix with the blood passed at 18.

The amount of blood filled in the entire circuit, that is, the priming volume, is determined by each tube 7,
8, the amount of blood is increased by the amount of blood filled in the portion from the portion corresponding to the lower end of each chamber body 3, 4 to the upper end of each chamber body 3, 4.

In the process of manufacturing the circuit, the work of connecting the tube to the upper end of each chamber body 3, 4 and the work of connecting the tube to the lower end must be performed separately, which takes time and effort.

Since the tubes hang down from the upper and lower ends of each chamber body 3, 4, handling and operation of the tubes is troublesome.

D. Means for Solving the Problems The present invention provides a blood circuit for an engineered kidney, a blood circuit for an engineered liver, and other blood circuits, in which a blood inflow tube and a blood outflow tube are connected to the lower end of the chamber body, By providing a partition inside the chamber body that divides the space extending from the lower end to an appropriate height into a space that communicates with the blood inflow tube and a space that communicates with the blood outflow tube, the above-mentioned conventional problem can be solved. The purpose of this invention is to provide a blood circuit chamber that can solve these problems.

The present invention will be described in detail below based on FIGS. 1 to 8 of the drawings. Reference numeral 19 denotes an arterial chamber main body of a blood circuit for an artificial kidney, and a blood inlet 20 and a blood outlet 21 are provided at the lower end for blood flow. The diameter of the inlet 20 is smaller than the diameter of the blood inlet 21, and a hanging ring 22, a level adjustment line 23, and a pressure monitor line 24 are provided at the upper end. Reference numeral 25 denotes a partition wall provided inside the chamber body 19, which extends a space from the lower end of the chamber body 19 to an appropriate height out of the space of the chamber body 19.
It is provided so as to be divided into a space 26 communicating with the blood inlet 20 and a space 27 communicating with the blood outlet 21. Both side edges 49, 50 of this partition wall 25
There is a gap 5 between the chamber body 19 and the inner wall of the chamber body 19.
1, 52 are provided, or both side edges 49, 50
A gap 51 or 52 is provided between either one of them and the inner wall of the chamber body 19. 2
Reference numeral 8 designates a blood inflow tube, one end of which is connected to the blood inflow port 20, the other end connected to a shunt joint 30 for attaching the needle 29, and a part of the tube 28 that is connected to the blood pump. A pump action tube 31, a fluid replacement line 32, a heparin line 33, and a rubber tube 34 for blood collection and mixed injection, which are pressed by the pump, are connected respectively. 35 is a blood outflow tube, one end of which is connected to the blood outflow port 21, and the other end of which is a connector 3 for connection to the inlet of the dialysis machine.
6 is connected.

E. Function The arterial chamber main body 19 is suspended by the hanging ring 22 at a position above the dialysis machine, blood pump, heparin injector, and patient. Then, a blood inflow tube 28 is formed from the lower end of the arterial chamber main body 19.
and the blood outflow tube 35 hangs down.

In this state, the blood inflow tube 28 is connected to the patient's vein via the needle 29, and the blood outflow tube 3 is connected to the patient's vein through the needle 29.
5 is connected to the inlet of the dialysis machine via the connector 36 to form an arterial circuit, and by repeatedly pressing the pumping tube 31 with the blood pump, blood from the patient's veins passes through the blood inflow tube 28. Blood flows into the arterial chamber body 19 from below, rises in the space 26 under pump pressure, bypasses the upper part of the septum 25, flows down in the space 27, flows out from below the arterial chamber body 19, and enters the blood outflow tube. 35 to the dialysis machine. If air bubbles are mixed in the blood flowing into the chamber body 19 from the blood inflow tube 28, the air bubbles are carried above the chamber body 19 by the upward flow of blood, and the blood flows above the partition wall 25. During the detour process, the air bubbles are discharged into the air layer 56, thereby preventing the air bubbles from being mixed into the blood flowing down in the space 27.

F. Example In the venous circuit connected to the outlet of the dialysis machine, a blood inlet 37 and a blood outlet 38 are provided at the lower end of the venous chamber main body 36, for example as shown in FIG.
A hanging ring 39 and a level adjustment line 40 at the upper end,
A pressure monitor line 41 is provided inside the chamber body 36, and a filter mesh 55 supported so as to communicate with the blood inlet 37 is provided inside the chamber body 36.
One end of the blood inflow tube 42 is connected to the blood inflow tube 42, a connector 43 for connecting to the outlet of the dialyzer is connected to the other end of the blood inflow tube 42, and the blood outflow port 38 is connected to the connector 43 for connecting to the outlet of the dialyzer. Blood outflow tube 4
Connect one end of 4 to the blood outflow tube 44
At the other end of the venous circuit 47, a shunt joint 46 for attaching a needle 45 is connected.

The partition wall 25 may be formed with a taper 48 so as to be thick at the lower end and gradually become thinner as it reaches the upper end, as shown in the second figure, or may be formed so that it has the same thickness between the upper and lower ends. It may also be formed into. Further, both side surfaces of the partition wall 25 may be formed into flat surfaces or may be formed into concave surfaces 57 and 58 as shown in FIG.

The blood inlet 20 and the blood outlet 21 may be formed with tapers 53 and 54 as shown in FIG. 8 to prevent blood from remaining on their inner edges.

G. Effects of the invention Since the present invention is constructed as described above, it has the following effects.

When the chamber body is suspended, the blood inflow tube hangs down from the lower end of the chamber body together with the blood outflow tube, and there is no possibility that the tube wall of the blood inflow tube will break near the upper end of the chamber body as in the prior art.

Blood enters the chamber body from the bottom and exits from the bottom after bypassing the upper part of the septum, which prevents air bubbles from entering and foaming.

Compared to the conventional case where the blood inflow tube is connected to the upper end of the chamber body, the length of the tube can be shortened, so the priming volume can be reduced.

In the circuit manufacturing process, the tube can be connected only at the lower end of the chamber body, which saves manufacturing time and improves manufacturing efficiency.

Since the tube hangs only from the lower end of the chamber body, handling and operation of the tube is facilitated.

Because the diameter of the connection port of the blood inflow tube is smaller than the diameter of the connection port of the blood outflow tube, the blood inflow speed is high and the outflow speed is slow. It is possible to forcefully send the air into the upper air layer of the interior of the tank.
Air bubbles can be easily removed compared to a blood circuit chamber in which a blood inflow tube and a blood outflow tube of the same diameter are connected as described in Japanese Patent No. 126844.

In the chambers for blood circuits described in each of the above-mentioned publications, it is difficult to collect the blood remaining in the chamber body from one space to the other after dialysis. Because there is a gap between the chamber and the inner wall of the chamber body, when blood remaining in the circuit is returned to the patient's body after dialysis,
By only slightly tilting the chamber body, blood in the space on the blood inlet side can be easily collected into the space on the blood outflow side.

[Brief explanation of drawings]

FIG. 1 is an explanatory diagram of an arterial circuit in an engineered kidney blood circuit incorporating a blood circuit chamber according to the present invention, FIG. 2 is a longitudinal cross-sectional view of a main part of an embodiment of the present invention, and FIG. Sectional view taken along line A-A in Figure 2, No. 4
5 is a side view of FIG. 2, FIG. 5 is an end view of the lower end of FIG. 4, FIG. 6 is a diagram showing an example of a venous circuit used with the arterial circuit of FIG. 1, and FIG. FIG. 8 is a sectional view showing another modified embodiment of the present invention, and FIG. 9 is an explanatory diagram of a conventional blood circuit for an engineered kidney. 19... Arterial chamber body, 20... Blood inflow port, 21... Blood outflow port, 25... Partition wall, 2
6, 27...Space, 28...Blood inflow tube,
35...Blood outflow tube.

Claims (1)

[Claims] 1 Connect the blood inflow tube and blood outflow tube to the lower end of the chamber body, and create a space inside the chamber body that extends from the lower end to an appropriate height.
In a blood circuit chamber that is provided with a partition wall that separates a space that communicates with a blood inflow tube and a space that communicates with a blood outflow tube, the diameter of the connection port of the blood inflow tube is smaller than the diameter of the connection port of the blood outflow tube. A chamber for a blood circuit, characterized in that the chamber is molded to provide a gap between both side edges or one side edge of the partition wall and the inner wall of the chamber body.