JPH04108707A - Vermin-repellent containing essential oil of japanese cypress as active component - Google Patents

Abstract

PURPOSE:To obtain a vermin-repellent having high safety and low residual toxicity and effective for mosquito, gnat, Stomoxys calcitrans, sandfly, ceratopogonid, cockroach, etc., by extracting essential oil from Japanese cypress e.g. by the steam-distillation of the wood and leaf of the tree and using the essential oil as an active component. CONSTITUTION:The objective vermin-repellent having the form of lotion, aerosol, cream, etc., can be produced by using 1-20wt.% of essential oil of Japanese cypress, adding an additive such as emulsifier, humectant, preservative and propellant to the oil as necessary and compounding the mixture to a carrier such as water, alcohol and aliphatic hydrocarbon. It can be micro-encapsulated and used in the form of lotion, aerosol, etc. The amount of the vermin-repellent is 0.05-0.5mg of the essential oil of Japanese cypress per 1cm<2> of the skin to be treated.

Description

DETAILED DESCRIPTION OF THE INVENTION <Public funds for industrial use> The present invention relates to a pest repellent containing as an active ingredient essential oil obtained from cypress trees or leaves.

<Prior art and problems to be solved by the invention> Conventionally, N,N-diethyl-m-toluamide (hereinafter referred to as Deet) has been used as an insect repellent for pests including Culex mosquitoes, Aedes mosquitoes, and Anopheles mosquitoes. Spray as a repellent for sharks and blood-sucking pests such as blackflies and stable flies.
It has been used in the form of lowsilane, cream, etc. However, there are many drawbacks, such as questions being raised regarding its safety.

Means for Solving the Problems> In view of this situation, the present inventors conducted intensive research to obtain a better pest repellent, and as a result, they developed a method using cypress trees or leaves that are already commercially available. We have discovered that essential oil obtained by steam distillation (hereinafter referred to as cypress essential oil) has a strong repellent effect against various pests, and have completed the present invention.

The pest repellent according to the present invention attempts to effectively utilize naturally occurring essential oil components, and is characterized by high safety and low residual toxicity.

Examples of the pests to which the pest repellent of the present invention is effective include blackflies such as Aedes albopictus and Aedes albopictus, blood-sucking pests such as sandflies, sandflies, and black flies, and sanitary pests such as house flies and cockroaches.

The pest repellent of the present invention can be used as a composition (hereinafter referred to as the present composition) usually blended with a suitable carrier,
For example, it is prepared and used in the form of a liquid preparation such as low silane or an aerosol, or a cream preparation.

Examples of carriers used in preparing liquid preparations include water, methanol, ethanol, glycerin, alcohols such as polyethylene glycol, tetrahydrofuran,
Examples include ethers such as dioxane, aliphatic hydrocarbons such as hexane, kerosene, paraffin, petroleum benzene, and esters such as ethyl acetate.

The liquid preparation can further contain formulation auxiliaries such as ordinary emulsifiers or dispersants, spreading/wetting agents, suspending agents, preservatives, and propellants, as well as ordinary film forming agents. can also be blended.

Specifically, for example, soaps, polyoxyethylene fatty acid alcohol ethers such as polyoxyethylene oleyl ether, polyoxyethylene alkylaryl ethers such as polyoxyethylene nonylphenyl ether, polyoxyethylene fatty acid esters, fatty acid glycerides,
Emulsifiers such as sorbitan fatty acid esters, sulfuric esters of higher alcohols, fulkylaryl sulfonates such as dodecylbenzenesulfone-coated soda, spreading and wetting agents such as glycerin and polyethylene glycol, casein, gelatin, alginic acid, carboxymethyl and lullose, Gum arabic, hydroxypropyl cellulose, bentonite, etc., paraoxybenzoic acid, paraoxybenzoic acid, preservatives such as methyl, ethyl paraoxybenzoate, propyl paraoxybenzoate, butyl paraoxybenzoate, dimethyl ether,
Examples include propellants such as chlorofluorocarbon and carbon dioxide, cellulose derivatives such as nitrocellulose, acetylcellulose, acetylbutyrylcellulose, and methylcellulose, vinyl resins such as vinyl acetate resin, and various film forming agents such as polyvinyl alcohol. .

In addition, carriers used in the preparation of creams include, for example, hydrocarbons such as liquid paraffin, vaseline, and paraffin, silicones such as dimethylsiloxane, colloidal silica, and bentonite, ethanol, stearyl alcohol, and lauryl alcohol. alcohol,
Examples include polyhydric alcohols such as polyethylene glycol, ethylene glycol, and glycerin, carboxylic acids such as lauric acid and stearic acid, and esters such as beeswax and lanolin. Furthermore, formulation auxiliaries similar to those for liquid preparations can also be added and blended.

Furthermore, prepared in a microencapsulated form,
It can also be used in formulations such as low silane and aerosol.

The composition may also include other pest repellents, synergists, antioxidants,
Other additives etc. can also be blended.

Other pest repellents that can be blended include, for example, Deet
, 2.8.4.5-bis(△2-butylene)tetrahydrofurfural, di-n-propylisocincomeronate, di-n-butylsuccibo 4,2~ and droxyethyloctylsulfide and empenthrin (1 -ethynyl-2-methyl-2-pentenyl d-cis, trans-chrysansemate (cis:trans ratio = 228))
Synergists include piperonyl butoxide, isobornyl thiocyanate, S-421, etc., and antioxidants include butylhydroxyanisole, dibutylhydroxytoluene, tocopherol, γ-
Examples include oryzanol and the like.

The amount of cypress essential oil, which is an active ingredient in this composition, varies depending on the dosage form and application method, but for example, when used in liquid preparations such as Rosilane and aerosol, or cream preparations,
The amount of active ingredient is 0.1 to 50% by weight, preferably 1 to 20% by weight.
Weight%.

The treatment amount of this composition is usually 1 cIi of skin area, and 0.01 to 14. Preferably, O,
OS~0.511? <Practical Examples> Next, the present invention will be further specifically explained by giving formulation examples and test examples, but the present invention is not limited only to these practical examples. do not have.

Formulation Example 1 Dissolve 10 parts of cypress essential oil in ethanol to give a total of 35 parts.
volume and fill it into an aerosol container.

Then, after attaching a valve, 65 parts of a 1:1 mixture (propellant) of Freon 11 and 12 is filled under pressure through the valve part to obtain an aerosol.

Test Example 1 200 to 400 adult Mosquito mosquitoes (sex ratio approximately 1:1)
A cage (22X 22X801) in which the animals were released was prepared. As an attraction source, a device was used in which a circulating *tu heating tank and two brown bottles (bottom diameter: 6-1, height: 10 cIn) were connected in series with silicone tubes, and warm water (38° C.) was circulated. 6X6c
A predetermined concentration of cypress essential oil (
s1 xylem or leaf essential oil) in acetone was applied. The processing amount is 500 capes/? ? / Closed. After air drying,
The back side of the semipermeable membrane was moistened with water and attached to the bottom of the brown bottle, and then tightly attached to one side of the cage. A brown bottle with an untreated semipermeable membrane was attached to the other side. 2.4 after close contact
．． The number of female mosquitoes attracted to each bottle was observed three times after 6 minutes. The number of mosquitoes is the total number tested in two batches. The results are shown in Table 1.

Table 1 Cypress tree essential oil 1 soo i o 0 Cypress leaf essential oil: 500: 0 30 no
-'95 102 Test Example 2 Acetone ilIwl of cypress essential oil (tree part or leaf essential oil) diluted to a predetermined concentration was placed in a triangular shelter (-side 31, length 61) made of F paper. 0.9 CI-coated. After air-drying, put it in a poly cup (diameter 1a=y,
Height 7 att), food (small amount of solid food for mice)
and a cotton ball soaked in water. Thereafter, five male and female German cockroaches were released into the cup, and the cup was covered with nylon gauze. The number of insects not in contact with the shelter was counted the next morning using one cup. The drug dose was 5oooII9/m", and the test was conducted at 2 ml. The number of insects is the total number of the 2 ml test. The results are shown in Table 2.
It was shown to.

The repellency rate was calculated using the following formula.

<Effects of the Invention> This cypress essential oil exhibits an excellent repellent effect on blood-sucking pests such as blackflies, stable flies, sandflies, and black flies, as well as sanitary pests such as cockroaches and houseflies, and is a natural product. Therefore, its residual toxicity is also low.

Table 2

Claims (1)

[Claims] A pest repellent characterized by containing essential oil obtained from cypress trees or leaves as an active ingredient.