JPH0419852B2 - - Google Patents
Info
- Publication number
- JPH0419852B2 JPH0419852B2 JP58063640A JP6364083A JPH0419852B2 JP H0419852 B2 JPH0419852 B2 JP H0419852B2 JP 58063640 A JP58063640 A JP 58063640A JP 6364083 A JP6364083 A JP 6364083A JP H0419852 B2 JPH0419852 B2 JP H0419852B2
- Authority
- JP
- Japan
- Prior art keywords
- ophthalmological
- eye
- examined
- physiological characteristics
- photographing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003287 optical effect Effects 0.000 claims description 11
- 238000005259 measurement Methods 0.000 claims description 5
- 230000002207 retinal effect Effects 0.000 claims description 5
- 208000006550 Mydriasis Diseases 0.000 claims description 2
- 230000003321 amplification Effects 0.000 claims description 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 2
- 210000001508 eye Anatomy 0.000 description 19
- 238000000034 method Methods 0.000 description 6
- 230000035790 physiological processes and functions Effects 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 238000003745 diagnosis Methods 0.000 description 4
- 238000005286 illumination Methods 0.000 description 4
- 230000002911 mydriatic effect Effects 0.000 description 3
- 208000017442 Retinal disease Diseases 0.000 description 2
- 210000004087 cornea Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 206010038923 Retinopathy Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 210000003710 cerebral cortex Anatomy 0.000 description 1
- 230000004300 dark adaptation Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000763 evoking effect Effects 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 239000002637 mydriatic agent Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000004382 visual function Effects 0.000 description 1
- 210000000239 visual pathway Anatomy 0.000 description 1
- 230000004400 visual pathway Effects 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Eye Examination Apparatus (AREA)
Description
【発明の詳細な説明】
本発明は、例えば眼底カメラにおける眼底の観察
撮影ための照射光によつて、眼科生理学的機能を
併せて計測する眼科装置に関するものである。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an ophthalmologic apparatus that also measures ophthalmological physiological functions using, for example, irradiated light for observing and photographing the fundus of the eye using a fundus camera.
眼底カメラは眼科領域での病変の診断に停まら
ず、内科や神経科等の領域でも広く使用されるよ
うになつてきているが、最近では人口の老齢化と
成人病検診の普及に伴い、特に散瞳剤を使用しな
い無散瞳眼底カメラの要求が高まりつつある。 Fundus cameras are being used not only for diagnosing lesions in the ophthalmology field, but also in fields such as internal medicine and neurology. In particular, there is an increasing demand for non-mydriatic fundus cameras that do not use mydriatic agents.
ところで、視機能診断での検査法の一つとし
て、網膜活動電位や視覚誘発電位特性等の眼科生
理学的機能を計測する手段が知られているが、こ
れは被検眼への光刺激によつて生ずる眼球或いは
大脳皮質領の電位変化を計測するものである。そ
して、これらは網膜疾患や視路機能の良否の判断
に欠くことのできない手法となつていると共に、
網膜症の一環として糖尿病の初期診断や、重症度
の判定、進展の予知に有効な方法と云われてい
る。 By the way, as one of the testing methods for visual function diagnosis, there is a known method for measuring ophthalmological physiological functions such as retinal action potential and visual evoked potential characteristics, but this method is based on optical stimulation of the eye to be examined. It measures the potential changes that occur in the eyeball or cerebral cortex. These methods have become indispensable methods for determining retinal diseases and the quality of visual pathway function.
It is said to be an effective method for the initial diagnosis of diabetes, determining its severity, and predicting its progression as part of retinopathy.
従来から上述の眼科生理学的機能を計測するに
当つては、被検眼を刺激する投光手段及び記録手
段、モニタスコープ等を用いて計測を行い、別個
に撮影した眼底像との対応等により更に診断効果
を高めたり独立した診断価値を持たせることが行
われている。 Conventionally, in measuring the above-mentioned ophthalmological physiological functions, measurements are performed using a light projecting means that stimulates the subject's eye, a recording means, a monitor scope, etc. Efforts are being made to improve the diagnostic effect or to provide independent diagnostic value.
本発明に目的は、被検眼の観察撮影時に眼科生
理学的機能をも同時に計測し、時間的な一致性を
求めて同一症例に対して別の角度からの診断を下
すことにより、その診断の信頼性を高めることが
できる眼科装置を提供することにあり、その要旨
は、被検眼に光束を投光する手段と、該被検眼か
らの反射光束を受光して被検眼の眼底を無散瞳で
観察撮影する手段とを有する装置において、前記
被検眼を観察撮影するための光束を光刺激として
眼科生理学的特性を計測する手段を有することを
特徴とするものである。 The purpose of the present invention is to measure ophthalmological physiological functions at the same time when observing and photographing the subject's eye, and by making a diagnosis of the same case from different angles with the aim of achieving temporal consistency, it is possible to increase the reliability of the diagnosis. The objective is to provide an ophthalmological device that can improve the performance of the eye, and its gist is to provide a means for projecting a light beam onto the eye to be examined, and a means for receiving the reflected light beam from the eye to be examined to illuminate the fundus of the eye to be examined without mydriasis. The apparatus is characterized in that it has a means for measuring ophthalmological physiological characteristics using a light beam for observing and photographing the eye to be examined as a light stimulus.
本発明を図示の実施例に基づいて詳細に説明す
る。 The present invention will be explained in detail based on illustrated embodiments.
第1図は眼底カメラの光学系の一実施例を示す
構成図であり、1はタングステンランプ等から成
る観察光源であり、この観察光源1から発光され
た光は、赤色フイルタ2、コンデンサレンズ3、
キセノン放電管等から成る撮影光源4、コンデン
サレンズ5を介してミラー6に入射し、ここで偏
向され順次にリングスリツト板7、リレーレンズ
8,9を経由して穴開きミラー10に到達するよ
うになつている。上述照明光学系から穴開きミラ
ー10に入射した光は、穴開きミラー10により
被検眼Eの方向に反射され、被検眼Eの眼底を照
射し元の光路を通り、更に穴開きミラー10を透
通して観察光学系に至ることになる。穴開きミラ
ー10と被検眼Eとの間には対物レンズ11が配
置されており、穴開きミラー10の背後には光軸
に沿つてフオーカシングレンズ12、撮影レンズ
13、跳ね上げミラー14、シヤツタ15、撮影
フイルム16が順次に配列されている。跳ね上げ
ミラー14の反射側には、光軸に沿つて順次に撮
影フイルム16と共役の位置に置かれたフイール
ドレンズ17、光路を変更するミラー18、リレ
ーレンズ19、撮像管20が配置されている。 FIG. 1 is a configuration diagram showing an embodiment of the optical system of a fundus camera. Reference numeral 1 is an observation light source consisting of a tungsten lamp, etc., and the light emitted from this observation light source 1 is passed through a red filter 2, a condenser lens 3, etc. ,
The light enters a mirror 6 through a photographing light source 4 consisting of a xenon discharge tube or the like, a condenser lens 5, is deflected there, and sequentially passes through a ring slit plate 7, relay lenses 8 and 9, and reaches a perforated mirror 10. It's getting old. The light that enters the perforated mirror 10 from the illumination optical system described above is reflected by the perforated mirror 10 in the direction of the eye E to be examined, illuminates the fundus of the eye E, passes through the original optical path, and is further transmitted through the perforated mirror 10. This leads to the observation optical system. An objective lens 11 is arranged between the perforated mirror 10 and the subject's eye E, and behind the perforated mirror 10, along the optical axis, there are a focusing lens 12, a photographing lens 13, a flip-up mirror 14, A shutter 15 and photographic film 16 are arranged in sequence. On the reflection side of the flip-up mirror 14, a field lens 17 placed at a position conjugate with the photographic film 16, a mirror 18 for changing the optical path, a relay lens 19, and an image pickup tube 20 are arranged in sequence along the optical axis. There is.
この眼底カメラにおいては、照明光源1と撮影
光源4はコンデンサレンズ3に対してほぼ共役関
係にあり、観察時には観察光源1が点灯され、撮
影フイルム16による撮影時には撮影光源4が瞬
時的に点灯される。光源像は別のコンデンサレン
ズ5によりリングスリツト板7の近傍に一旦結線
され、次いでリレーレンズ8,9によりリングス
リツト板7の課状開口の像が穴開きミラー10の
近傍に結像され、ここで照明光は反射され左行す
る。そして、対物レンズ11により被検眼Eの角
膜の近傍に環状開口の像を結んだ後に眼底を照明
する。 In this fundus camera, the illumination light source 1 and the photographing light source 4 are in a substantially conjugate relationship with the condenser lens 3, and the observation light source 1 is turned on during observation, and the photographing light source 4 is turned on instantaneously when photographing with the photographic film 16. Ru. The light source image is once connected to the vicinity of the ring slit plate 7 by another condenser lens 5, and then the image of the sectioned aperture of the ring slit plate 7 is formed in the vicinity of the perforated mirror 10 by the relay lenses 8 and 9. The illumination light is reflected and travels to the left. Then, after forming an image of the annular aperture near the cornea of the eye E to be examined using the objective lens 11, the fundus of the eye is illuminated.
眼底からの反射光は右行し、角膜及び対物レン
ズ11により一旦結像した後に、穴開きミラー1
0を通過し、フオーカシングレンズ12及び撮影
レンズ13によつて合焦結像されることになる。
観察時には、眼底像は実線位置にある跳ね上げミ
ラー14により上方に導かれ、撮像管20を介し
てTVモニタによつて観察され、フイルム撮影時
には跳ね上げミラー14が点線位置に回転し、眼
底像は瞬時的に開放されたシヤツタ15を経由し
て撮影フイルム16に結像することになる。 The reflected light from the fundus travels to the right, and after being imaged by the cornea and objective lens 11, it passes through the perforated mirror 1.
0, and is focused and imaged by the focusing lens 12 and the photographing lens 13.
During observation, the fundus image is guided upward by the flip-up mirror 14 located at the solid line position, and is observed on a TV monitor via the image pickup tube 20. During film photography, the flip-up mirror 14 rotates to the dotted line position, and the fundus image is is formed on the photographic film 16 via the shutter 15 which is instantaneously opened.
なお本実施例においては、写真撮影時には次に
述べる眼科生理学的機能を計測する装置を備えて
いる。即ち、被検眼Eの瞼の近くに関電極30、
耳ぶたの後方に不関電極31、耳ぶたに接地電極
32を接続すると、撮影光源4の発光に伴う光刺
激により網膜活動電位が測定される。 Note that this embodiment is equipped with a device for measuring the following ophthalmological physiological functions when taking photographs. That is, the related electrode 30 is placed near the eyelid of the eye E to be examined.
When an indifferent electrode 31 is connected to the rear of the earlid and a ground electrode 32 is connected to the earlid, a retinal action potential is measured by light stimulation caused by light emission from the photographing light source 4.
関電極30、不関電極31により得られた波形
は、直流増幅回路33を介してCRT34に接続
されている。一方、撮影光源4の発光はスイツチ
35により起動されるが、これはリレー回路36
を経て行われると共に、トリガ回路37に信号が
送られ、更に帰引回路38を経てCRT34に出
力されている。CRT34の画面の前方には、順
次にレンズ39、偏向ミラー40が配置され、
CRT34の画像は跳ね上げミラー14方向に導
光され、撮影光束内に入射するようになつてい
る。 The waveforms obtained by the related electrode 30 and the indifferent electrode 31 are connected to the CRT 34 via a DC amplifier circuit 33. On the other hand, the light emission of the photographing light source 4 is started by the switch 35, but this is controlled by the relay circuit 36.
At the same time, a signal is sent to the trigger circuit 37, and is further output to the CRT 34 via the return circuit 38. A lens 39 and a deflection mirror 40 are sequentially arranged in front of the screen of the CRT 34.
The image on the CRT 34 is guided in the direction of the flip-up mirror 14 and is made to enter the photographing light flux.
従つて、撮影時には関電極30、不関電極31
による網膜活動電位が、第2図に示すように
CRT34上に画像化され、レンズ39、偏向ミ
ラー40を介して撮影フイルム16に眼底像と共
に写し込まれる。 Therefore, during imaging, the related electrode 30 and the indifferent electrode 31 are
As shown in Figure 2, the retinal action potential due to
The image is formed on the CRT 34 and transferred to the photographic film 16 through the lens 39 and the deflection mirror 40 together with the fundus image.
上述の実施例は赤色フイルタ2を用いた無散瞳
眼底カメラを用いた暗順応下の網膜活動電位の計
測例であるが、赤色フイルタ2を取り外した順応
下でも同様に計測可能である。また、電極の位置
ついてはその測定用途により変え得ることは云う
までもない。 Although the above-described embodiment is an example of measuring retinal action potentials under dark adaptation using a non-mydriatic fundus camera using a red filter 2, measurement is also possible under adaptation with the red filter 2 removed. Furthermore, it goes without saying that the position of the electrodes can be changed depending on the purpose of measurement.
また、本実施例では撮影フイルム16の感度を
変更した場合に、第3図に示すような回転型濃度
フイルタ45を照明光束中又は撮影光束中に挿入
して光量調整を行うことができる。この濃度フイ
ルタ45を回転し、濃度を適当に自動又は手動で
選択することにより、被検眼Eを刺激する光量を
常に一定に保持することが可能である。この光量
補正は、その他にもフイルタの交換や光電的手
法、開口絞りの大きさを変えるなどの機械的方法
によつても実施できる。また、被検眼Eに照射す
る光量の変化に伴つて直流増幅回路33の増幅度
を変え、出力波形のレベルを所謂対照波形と合致
させることにより、正常対照波形と比較して判断
をすることもできる。 Furthermore, in this embodiment, when the sensitivity of the photographic film 16 is changed, the light amount can be adjusted by inserting a rotary density filter 45 as shown in FIG. 3 into the illumination light beam or into the photographing light beam. By rotating the density filter 45 and appropriately selecting the density automatically or manually, it is possible to always maintain a constant amount of light that stimulates the eye E to be examined. This light amount correction can also be performed by mechanical methods such as filter replacement, photoelectric methods, and changing the size of the aperture stop. Furthermore, by changing the amplification degree of the DC amplifier circuit 33 in accordance with changes in the amount of light irradiated to the eye E to match the level of the output waveform with a so-called reference waveform, it is also possible to make a judgment by comparing it with a normal reference waveform. can.
更には、本発明は次に述べるような用途にも使
用することができる。 Furthermore, the present invention can also be used in the following applications.
(1) 第4図に示すようにCRT34とレンズ39
との間にハーフミラー50を配置して、チヤー
ト51上の正常対照波形像を合成することによ
り、得られた眼科生理学的特性を比較して判断
することができる。(1) As shown in Figure 4, CRT34 and lens 39
By arranging a half mirror 50 between the two and combining the normal control waveform images on the chart 51, the obtained ophthalmological physiological characteristics can be compared and judged.
(2) 眼底カメラに限らず、前眼部観察撮影装置等
に応用することによつて本機能を満足させるこ
とができる。(2) This function can be satisfied by applying not only to a fundus camera but also to an anterior ocular segment observation and photographing device.
(3) 眼科生理学的特性の記録を、別の記録紙に出
力しその記録紙に正常対照波形を書き込むこと
もできる。(3) It is also possible to output the record of the ophthalmological physiological characteristics on a separate recording paper and write the normal control waveform on that recording paper.
以上説明したように本発明に係る眼科装置は、
観察撮影時に被検眼の眼科生理学的機能も計測で
き、検診の機能を拡大することが可能となり、異
なつた観点から同一検査項目を判断できるため、
判断の信頼性が向上する効果がある。また、測定
は無散瞳状態で行うため眼科生理学的特性の測定
に好適となる。 As explained above, the ophthalmological device according to the present invention includes:
The ophthalmological physiological functions of the eye to be examined can also be measured during observation photography, making it possible to expand the functionality of examinations and making it possible to judge the same examination item from different perspectives.
This has the effect of improving the reliability of judgment. Furthermore, since the measurement is performed in a non-mydriatic state, it is suitable for measuring ophthalmological physiological characteristics.
図面は本発明に係る眼科装置の実施例を示し、
第1図はその光学的配置図、第2図はCRTで表
示される画像の説明図、第3図は濃度フイルタの
正面図、第4図は正常対照波形を画像に合成する
ための光学的配置図である。
符号1は観察光源、2は赤色フイルタ、4は撮
影光源、7はリングスリツト板、10は穴開きミ
ラー、11は対物レンズ、14は跳ね上げミラ
ー、16は撮影フイルム、20は撮像管、30は
関電極、31は不関電極、33は直流増幅回路、
34はCRT、35はスイツチ、36はリレー回
路、45は濃度フイルタ、Eは被検眼である。
The drawings show an embodiment of the ophthalmological device according to the invention,
Figure 1 is a diagram of its optical layout, Figure 2 is an explanatory diagram of an image displayed on a CRT, Figure 3 is a front view of the density filter, and Figure 4 is an optical diagram for compositing a normal control waveform into an image. It is a layout diagram. 1 is an observation light source, 2 is a red filter, 4 is a photographic light source, 7 is a ring slit plate, 10 is a perforated mirror, 11 is an objective lens, 14 is a flip-up mirror, 16 is a photographic film, 20 is an imaging tube, 30 is a related electrode, 31 is an indifferent electrode, 33 is a DC amplifier circuit,
34 is a CRT, 35 is a switch, 36 is a relay circuit, 45 is a density filter, and E is an eye to be examined.
Claims (1)
らの反射光束を受光して被検眼の眼底を無散瞳で
観察撮影する手段とを有する装置において、前記
被検眼を観察撮影するための光束を光刺激として
眼科生理学的特性を計測する手段を有することを
特徴とする眼科装置。 2 前記眼科生理学的特性を前記撮影結果と共に
記録するようにした特許請求の範囲第1項に記載
の眼科装置。 3 前記眼底撮影を行うための光学的信号を、前
記眼科生理学的特性の計測のためのトリガ信号と
した特許請求の範囲第1項に記載の眼科装置。 4 前記眼科生理学的特性の記録は、CRTに表
示した測定結果を撮影手段中に導光することによ
り行う特許請求の範囲第2項に記載の眼科装置。 5 前記眼科生理学的特性は被検眼の観察手段に
表示するようにした特許請求の範囲第1項に記載
の眼科装置。 6 前記眼科生理学的特性は被検眼の撮影画像と
共にフイルムに記録するようにした特許請求の範
囲第2項に記載の眼科装置。 7 被検眼を照明する光量の変化に従つて、前記
眼科生理学的特性の増幅度を変化させるようにし
た特許請求の範囲第1項に記載の眼科装置。 8 前記眼科生理学的特性を網膜活動電位特性と
した特許請求の範囲第1項に記載の眼科装置。[Scope of Claims] 1. An apparatus having a means for projecting a light beam onto an eye to be examined, and a means for receiving a reflected light beam from the eye to be examined and observing and photographing the fundus of the eye to be examined without mydriasis, the apparatus comprising: An ophthalmological apparatus characterized by having means for measuring ophthalmological physiological characteristics using a light beam for observing and photographing an eye as a light stimulus. 2. The ophthalmological apparatus according to claim 1, wherein the ophthalmic physiological characteristics are recorded together with the photographic results. 3. The ophthalmological apparatus according to claim 1, wherein the optical signal for photographing the fundus is a trigger signal for measuring the ophthalmic physiological characteristics. 4. The ophthalmological apparatus according to claim 2, wherein the ophthalmic physiological characteristics are recorded by guiding the measurement results displayed on a CRT into a photographing means. 5. The ophthalmological apparatus according to claim 1, wherein the ophthalmological physiological characteristics are displayed on a means for observing the eye to be examined. 6. The ophthalmological apparatus according to claim 2, wherein the ophthalmological physiological characteristics are recorded on a film together with a photographed image of the eye to be examined. 7. The ophthalmological apparatus according to claim 1, wherein the degree of amplification of the ophthalmic physiological characteristics is changed in accordance with a change in the amount of light illuminating the eye to be examined. 8. The ophthalmological device according to claim 1, wherein the ophthalmological physiological characteristic is a retinal action potential characteristic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58063640A JPS59189823A (en) | 1983-04-13 | 1983-04-13 | ophthalmology equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58063640A JPS59189823A (en) | 1983-04-13 | 1983-04-13 | ophthalmology equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59189823A JPS59189823A (en) | 1984-10-27 |
| JPH0419852B2 true JPH0419852B2 (en) | 1992-03-31 |
Family
ID=13235152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58063640A Granted JPS59189823A (en) | 1983-04-13 | 1983-04-13 | ophthalmology equipment |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59189823A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2108308A1 (en) | 2008-04-10 | 2009-10-14 | Kowa Company Ltd. | Ocular light stimulus apparatus |
-
1983
- 1983-04-13 JP JP58063640A patent/JPS59189823A/en active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2108308A1 (en) | 2008-04-10 | 2009-10-14 | Kowa Company Ltd. | Ocular light stimulus apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59189823A (en) | 1984-10-27 |
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