JPH0441329Y2 - - Google Patents

Description

[Detailed description of the invention] (a) Industrial application field The present invention relates to a blood dripping device that is optimal for dripping plasma in blood, and in particular a microsyringe and a pipette tip that suck and eject blood by air transmission. This device uses an elastic flexible pipe between the air pipe section and the signal line from the controller.

(B) Prior Art Generally, a blood test device separates each component using a centrifuge, collects plasma, etc., and then performs each analysis test. In this case, large-scale equipment is automated, with as few manual parts as possible, but requires very large-scale equipment.

Therefore, for example, there is a method in which, after performing the above-mentioned centrifugation, the plasma in the blood is transferred using a microsyringe onto a test table or test plate for testing.

Japanese Patent Application Laid-Open No. 181057/1986 is a device for collecting plasma samples from blood, which is equipped with a blood flow chamber and a plasma chamber, in which plasma is filtered from the constantly flowing blood. The configuration is as follows.

(d) Means for Solving the Problems The present invention includes a controller that outputs various electrical signals in response to manual operations by an operator, a first actuator that drives the microsyringe, and a second actuator that drives the pipette tip. In addition to being electrically connected, the microsyringe and a pipette tip portion from which blood is dripped are connected by a flexible pipe, and an air pipe portion and a signal line for electrical signals are housed in the flexible pipe.

(e) Effect This invention can be used in a semi-automatic blood analyzer that uses a pipette tip that is replaced with a new one every time the test solution is replaced. It is provided with an air flow path and a conductor for electrical connection, and furthermore, the actuator can be controlled by an operation switch provided on the pipette tip.

(F) Embodiments The present invention will be described with reference to the drawings. FIG. 1 is a block diagram of a blood dripping device of the present invention, and FIG. 2 is a sectional view of a main part for explaining the dripping operation of the device.

In the drawing, 1 is a first actuator, 2 is a microsyringe as an inhalation and ejection means, and 3 is a first actuator.
is the second actuator, 4 is the controller, 5 is the operation switch, and 6 is the conductor wire 7, 7 for the operation switch.
and a flexible pipe having an air pipe 8,
Reference numeral 9 denotes a specimen test slide; 10 a pipette portion having a dripping tip 11 and a tip holder 12 for aspirating and discharging the specimen; 13 a switch lever;
0 can be moved separately from the main body using a flexible pipe.

Next, to explain the operation of the device of the present invention, the operator removes the pipette part 10 from the arm 16 of the main body, dips the tip of the dripping tip 11 into the predetermined plasma, and presses the switch lever 13 of the operation switch 5 to open the microsyringe 2. The first actuator 1 is driven by the control signal from the controller 4 to move the piston 14 in the direction A, and the sample 15 is sucked into the dropping tip 11 as shown in FIG. At this time, the air flow path is configured from the microsyringe 2 through the flexible pipe 6 to the tip holder 12 and the dripping tip 11.

Next, the operator moves the pipette section 10 to arm 1 of the main body.
Install it on 6. In response to the control signal from the controller 4, the second actuator 3 descends in the direction of the arrow C, and moves from A to B in FIG. By operating an operation key (not shown), a control signal based on the optimum value preset in the controller 4 is applied to the first actuator 1, which moves the piston 14 of the microsyringe 2 in the direction B, and the tip of the dripping tip 11. Specimen 15 is dropped from the container.

The dripping amount is set in the controller 4,
Since the number of times of this is also set in advance, a control signal is applied from the controller 4 to the second actuator 3 at the end of a predetermined dripping operation, and the arm 16 to which the tip holder 12 is attached rises in the direction of arrow D and returns to the reference position. The test slide 9 to be dropped is automatically replaced every time a drop is dropped, and the specimen 15 is discharged from the drop tip 11 to a predetermined number (for example,
10 or 12) onto the test slide as shown in Figure 2 A and B.

Next, the specimen dropped onto the test slide is sequentially dropped onto a plurality of test slides in the same manner as shown in FIG. 2B, and is tested. When the test of a predetermined person's specimen has been completed with the plurality of test slides, the operator removes the dripping tip 11 from the tip holder 12, replaces it with a new dripping tip, and then presses down the switch lever 13 of the operation switch 5 to select the predetermined number of slides. An instruction signal for inhaling the sample is applied to the controller 4, and the sample is inhaled from the tip of the dripping tip 11 in the same manner as described above, and the amount of inhalation preset by the controller 4 accumulates in the tip 11, causing the piston 14 to inhale. The work is finished.

At this time, the second actuator 3 is controlled by operating a predetermined key among various operation keys provided on the controller 4. In addition, in response to the control signal output from the controller 4, control signals such as control of the first actuator 1 that controls the piston 14 of the microsyringe 2, and movement of the arm 16 up and down to the inspection slide 9 are sent to the controller in advance. When operated using the provided keys, predetermined operations are performed.

As described above, the device of the present invention has a semi-automated configuration in which a predetermined amount of blood as a specimen (such as plasma separated from blood) is inhaled using the air pressure of a microsyringe for testing, and then placed on a test slide. It is dripped at.

An arm 16 in which the pipette section 10 is provided on the main body.
Since the pipette section 10 is detached from the arm 16, when a sample is aspirated and the pipette section 10 is attached to the arm 16 again, the attachment reference surface _S1 of the pipette section 10 to the arm 16 and the dripping tip 11 are the same. Mounting reference surface S ₂ on the tip holder 12
If is set accurately, it becomes extremely easy for the controller 4 to electrically drive the ascending and descending motions of the second actuator 3.

(g) Effects of the invention According to the device of the invention, the microsyringe is moved by the control signal from the controller.
When controlling the actuator and the second actuator that moves the dripping tip that drips the sample, the configuration is such that when the blood as the specimen is sucked into the dripping tip, an inhalation instruction signal is applied to the controller by operating an operation switch. This enables semi-automatic operation, and when the blood in the dripping tip has finished dripping, the operator can perform the inhalation operation at any time to the dripping tip, so the dripping tip can be exchanged for plasma as a sample and other liquids. It can also respond to the operator's operations.

[Brief explanation of the drawing]

Figure 1 is a configuration diagram of the blood dripping device of the present invention, Figure 2
The figure shows a sectional view of essential parts for explaining the dropping operation of the device. DESCRIPTION OF SYMBOLS 1...First actuator, 2...Micro syringe, 3...Second actuator, 4...Controller, 5...Operation switch, 6...Flexible pipe, 7...Conductor, 8...Air pipe, 1
0... Pipette part, 11... Dripping tip, 15...
...Specimen.

Claims (1)

[Scope of utility model registration request] a first actuator for driving the suction and ejection means; a microsyringe coupled to the actuator; a pipe connected between the microsyringe and the pipette tip; a second actuator for vertically moving the pipette tip; In a blood dripping device equipped with a controller for controlling two actuators, an air pipe section connecting the microsyringe and the dripping tip section to the pipe, and a signal line connecting the controller and an operation switch provided on the pipette tip section are connected in the pipe. A blood dripping device characterized by being housed in a.