JPH04505003A - 生体内の神経栄養、細胞保護性アルコール - Google Patents

生体内の神経栄養、細胞保護性アルコール

Info

Publication number
JPH04505003A
JPH04505003A JP1511596A JP51159689A JPH04505003A JP H04505003 A JPH04505003 A JP H04505003A JP 1511596 A JP1511596 A JP 1511596A JP 51159689 A JP51159689 A JP 51159689A JP H04505003 A JPH04505003 A JP H04505003A
Authority
JP
Japan
Prior art keywords
neurons
damage
alcohol
injury
hexacosanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1511596A
Other languages
English (en)
Japanese (ja)
Inventor
ボグ、ジャク
コトマン、カール ダブリュ
ケスラック、ジェイ パトリック
Original Assignee
ザ レジェンツ オブ ザ ユニバーシティ オブ カリフォルニア
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ レジェンツ オブ ザ ユニバーシティ オブ カリフォルニア filed Critical ザ レジェンツ オブ ザ ユニバーシティ オブ カリフォルニア
Publication of JPH04505003A publication Critical patent/JPH04505003A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP1511596A 1988-10-18 1989-10-16 生体内の神経栄養、細胞保護性アルコール Pending JPH04505003A (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US259,964 1981-05-04
US25991988A 1988-10-18 1988-10-18
US25991888A 1988-10-18 1988-10-18
US25996488A 1988-10-18 1988-10-18
US25992888A 1988-10-18 1988-10-18
US259,918 1988-10-18
US259,928 1988-10-18
US259,919 1988-10-18
US26930088A 1988-11-09 1988-11-09
US269,300 1988-11-09

Publications (1)

Publication Number Publication Date
JPH04505003A true JPH04505003A (ja) 1992-09-03

Family

ID=27540413

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1511596A Pending JPH04505003A (ja) 1988-10-18 1989-10-16 生体内の神経栄養、細胞保護性アルコール

Country Status (8)

Country Link
US (1) US5135956A (da)
EP (1) EP0439544B1 (da)
JP (1) JPH04505003A (da)
AU (1) AU633526B2 (da)
CA (1) CA2000940A1 (da)
DE (1) DE68913756T2 (da)
DK (1) DK69091A (da)
WO (1) WO1990004388A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166317A (en) * 1988-10-31 1992-11-24 Houston Biotechnology Incorporated Neurotrophic factor
US5070107A (en) * 1989-04-28 1991-12-03 Lidak Pharmaceuticals Systemic antiviral treatment
US5071879A (en) * 1989-04-28 1991-12-10 Lidak Pharmaceuticals Systemic antiviral treatment
WO1991005754A2 (fr) * 1989-10-13 1991-05-02 Medafor Derives des alcools gras a longue chaine, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
US6174862B1 (en) * 1991-04-22 2001-01-16 Ramot University Authority For Applied Research And Industrial Development, Ltd. Neurotrophic peptides of activity dependent neurotrophic factor
US5569670A (en) * 1992-06-05 1996-10-29 Asta Medica Aktiengesellschaft Combination medications containing alpha-lipoic acid and related
WO1994027602A1 (en) * 1993-06-01 1994-12-08 Cortex Pharmaceuticals, Inc. Use of metabotropic receptor agonists in progressive neurodegenerative deseases
US5952392A (en) * 1996-09-17 1999-09-14 Avanir Pharmaceuticals Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition
US6440980B1 (en) 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US5906976A (en) * 1996-10-22 1999-05-25 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Method and composition for treating neuronal degeneration
US6962930B1 (en) 1997-06-06 2005-11-08 Lohocla Research Corporation Compounds, compositions and method suitable for amelioration of withdrawal syndromes and withdrawal-induced brain damage
IT1294227B1 (it) * 1997-08-01 1999-03-24 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
US6506378B1 (en) 1998-12-16 2003-01-14 Arch Development Corporation Vesicular monoamine transporter gene therapy in Parkinson's disease
US6265147B1 (en) 1999-12-01 2001-07-24 The Board Of Trustees Of The Leland Stanford Junior University Method of screening for neuroprotective agents
HRP20040421B1 (hr) * 2001-10-16 2013-05-31 Avanir Pharmaceuticals INHIBICIJA VIRUSA n-DOKOZANOLOM
US7214394B2 (en) * 2002-05-31 2007-05-08 Archer-Daniels-Midland Company Policosanol compositions, extraction from novel sources, and uses thereof
US20050074443A1 (en) * 2003-10-03 2005-04-07 Treadwell Benjamin V. Methods of attenuating autoimmune disease and compositions useful therefor
US8202541B2 (en) * 2006-02-07 2012-06-19 U.S. Nutraceuticals, LLC Dietary supplement composition for blood lipid health
JP5173018B2 (ja) * 2008-04-03 2013-03-27 エフ.ホフマン−ラ ロシュ アーゲー 神経筋障害の処置のためのpeg化igf−i変異体の使用
WO2013082299A1 (en) 2011-11-29 2013-06-06 Als Therapy Development Institute Targeting of t-lymphocytes to treat amyotrophic lateral sclerosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3031376A (en) * 1956-10-11 1962-04-24 Levin Compositions comprising octacosanol, triacontanol, tetracosanol, or hexacosanol, andmethods employing same
US4186212A (en) * 1978-03-09 1980-01-29 Howell F Maurice Animal feed containing high molecular weight aliphatic alcohols
US5055613A (en) * 1988-02-18 1991-10-08 G. D. Searle & Co. Metabolites of pentanedioic acid derivatives
US4874794A (en) * 1989-04-28 1989-10-17 Lidak Biopharmaceuticals Inflammatory disease treatment

Also Published As

Publication number Publication date
DK69091A (da) 1991-06-14
EP0439544B1 (en) 1994-03-09
WO1990004388A1 (en) 1990-05-03
DE68913756T2 (de) 1994-08-11
US5135956A (en) 1992-08-04
DK69091D0 (da) 1991-04-17
AU4510889A (en) 1990-05-14
AU633526B2 (en) 1993-02-04
EP0439544A1 (en) 1991-08-07
DE68913756D1 (de) 1994-04-14
CA2000940A1 (en) 1990-04-18

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