JPH04505003A - 生体内の神経栄養、細胞保護性アルコール - Google Patents
生体内の神経栄養、細胞保護性アルコールInfo
- Publication number
- JPH04505003A JPH04505003A JP1511596A JP51159689A JPH04505003A JP H04505003 A JPH04505003 A JP H04505003A JP 1511596 A JP1511596 A JP 1511596A JP 51159689 A JP51159689 A JP 51159689A JP H04505003 A JPH04505003 A JP H04505003A
- Authority
- JP
- Japan
- Prior art keywords
- neurons
- damage
- alcohol
- injury
- hexacosanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 230000002792 vascular Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US259,964 | 1981-05-04 | ||
| US25991988A | 1988-10-18 | 1988-10-18 | |
| US25991888A | 1988-10-18 | 1988-10-18 | |
| US25996488A | 1988-10-18 | 1988-10-18 | |
| US25992888A | 1988-10-18 | 1988-10-18 | |
| US259,918 | 1988-10-18 | ||
| US259,928 | 1988-10-18 | ||
| US259,919 | 1988-10-18 | ||
| US26930088A | 1988-11-09 | 1988-11-09 | |
| US269,300 | 1988-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04505003A true JPH04505003A (ja) | 1992-09-03 |
Family
ID=27540413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1511596A Pending JPH04505003A (ja) | 1988-10-18 | 1989-10-16 | 生体内の神経栄養、細胞保護性アルコール |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5135956A (da) |
| EP (1) | EP0439544B1 (da) |
| JP (1) | JPH04505003A (da) |
| AU (1) | AU633526B2 (da) |
| CA (1) | CA2000940A1 (da) |
| DE (1) | DE68913756T2 (da) |
| DK (1) | DK69091A (da) |
| WO (1) | WO1990004388A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166317A (en) * | 1988-10-31 | 1992-11-24 | Houston Biotechnology Incorporated | Neurotrophic factor |
| US5070107A (en) * | 1989-04-28 | 1991-12-03 | Lidak Pharmaceuticals | Systemic antiviral treatment |
| US5071879A (en) * | 1989-04-28 | 1991-12-10 | Lidak Pharmaceuticals | Systemic antiviral treatment |
| WO1991005754A2 (fr) * | 1989-10-13 | 1991-05-02 | Medafor | Derives des alcools gras a longue chaine, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant |
| US5444042A (en) * | 1990-12-28 | 1995-08-22 | Cortex Pharmaceuticals | Method of treatment of neurodegeneration with calpain inhibitors |
| US6174862B1 (en) * | 1991-04-22 | 2001-01-16 | Ramot University Authority For Applied Research And Industrial Development, Ltd. | Neurotrophic peptides of activity dependent neurotrophic factor |
| US5569670A (en) * | 1992-06-05 | 1996-10-29 | Asta Medica Aktiengesellschaft | Combination medications containing alpha-lipoic acid and related |
| WO1994027602A1 (en) * | 1993-06-01 | 1994-12-08 | Cortex Pharmaceuticals, Inc. | Use of metabotropic receptor agonists in progressive neurodegenerative deseases |
| US5952392A (en) * | 1996-09-17 | 1999-09-14 | Avanir Pharmaceuticals | Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition |
| US6440980B1 (en) | 1996-09-17 | 2002-08-27 | Avanir Pharmaceuticals | Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs |
| US5906976A (en) * | 1996-10-22 | 1999-05-25 | Ramot-University Authority For Applied Research And Industrial Development, Ltd. | Method and composition for treating neuronal degeneration |
| US6962930B1 (en) | 1997-06-06 | 2005-11-08 | Lohocla Research Corporation | Compounds, compositions and method suitable for amelioration of withdrawal syndromes and withdrawal-induced brain damage |
| IT1294227B1 (it) * | 1997-08-01 | 1999-03-24 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione |
| US6506378B1 (en) | 1998-12-16 | 2003-01-14 | Arch Development Corporation | Vesicular monoamine transporter gene therapy in Parkinson's disease |
| US6265147B1 (en) | 1999-12-01 | 2001-07-24 | The Board Of Trustees Of The Leland Stanford Junior University | Method of screening for neuroprotective agents |
| HRP20040421B1 (hr) * | 2001-10-16 | 2013-05-31 | Avanir Pharmaceuticals | INHIBICIJA VIRUSA n-DOKOZANOLOM |
| US7214394B2 (en) * | 2002-05-31 | 2007-05-08 | Archer-Daniels-Midland Company | Policosanol compositions, extraction from novel sources, and uses thereof |
| US20050074443A1 (en) * | 2003-10-03 | 2005-04-07 | Treadwell Benjamin V. | Methods of attenuating autoimmune disease and compositions useful therefor |
| US8202541B2 (en) * | 2006-02-07 | 2012-06-19 | U.S. Nutraceuticals, LLC | Dietary supplement composition for blood lipid health |
| JP5173018B2 (ja) * | 2008-04-03 | 2013-03-27 | エフ.ホフマン−ラ ロシュ アーゲー | 神経筋障害の処置のためのpeg化igf−i変異体の使用 |
| WO2013082299A1 (en) | 2011-11-29 | 2013-06-06 | Als Therapy Development Institute | Targeting of t-lymphocytes to treat amyotrophic lateral sclerosis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3031376A (en) * | 1956-10-11 | 1962-04-24 | Levin | Compositions comprising octacosanol, triacontanol, tetracosanol, or hexacosanol, andmethods employing same |
| US4186212A (en) * | 1978-03-09 | 1980-01-29 | Howell F Maurice | Animal feed containing high molecular weight aliphatic alcohols |
| US5055613A (en) * | 1988-02-18 | 1991-10-08 | G. D. Searle & Co. | Metabolites of pentanedioic acid derivatives |
| US4874794A (en) * | 1989-04-28 | 1989-10-17 | Lidak Biopharmaceuticals | Inflammatory disease treatment |
-
1989
- 1989-10-13 US US07/420,904 patent/US5135956A/en not_active Expired - Fee Related
- 1989-10-16 JP JP1511596A patent/JPH04505003A/ja active Pending
- 1989-10-16 WO PCT/US1989/004630 patent/WO1990004388A1/en not_active Ceased
- 1989-10-16 AU AU45108/89A patent/AU633526B2/en not_active Ceased
- 1989-10-16 EP EP89912595A patent/EP0439544B1/en not_active Expired - Lifetime
- 1989-10-16 DE DE68913756T patent/DE68913756T2/de not_active Expired - Fee Related
- 1989-10-18 CA CA002000940A patent/CA2000940A1/en not_active Abandoned
-
1991
- 1991-04-17 DK DK069091A patent/DK69091A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK69091A (da) | 1991-06-14 |
| EP0439544B1 (en) | 1994-03-09 |
| WO1990004388A1 (en) | 1990-05-03 |
| DE68913756T2 (de) | 1994-08-11 |
| US5135956A (en) | 1992-08-04 |
| DK69091D0 (da) | 1991-04-17 |
| AU4510889A (en) | 1990-05-14 |
| AU633526B2 (en) | 1993-02-04 |
| EP0439544A1 (en) | 1991-08-07 |
| DE68913756D1 (de) | 1994-04-14 |
| CA2000940A1 (en) | 1990-04-18 |
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