JPH0454439Y2 - - Google Patents

Description

[Detailed explanation of the invention] (a) Technical field This invention is suitable for chemical analysis, detection of viruses,
This relates to a dispenser that manually adds a certain amount of reagent for purposes such as measuring antigens or antibody titers of bacteria, etc., and is particularly designed to allow multiple doses of the same amount of reagent to be dispensed at the same time.

(b) Prior art When analyzing and measuring multiple samples by adding reagents, with a conventional pipettor, the dispensing operation must be performed once for each container containing the test sample. When the number of liquids increases, the dispensing operation requires considerable effort.

Therefore, in recent years, dispensers have been proposed that allow the same amount of reagent to be added to multiple samples at the same time.
Each cylinder is equipped with a piston cylinder, and an inverted T-shaped rod is lowered by pressing an operation button to simultaneously discharge the reagent introduced into the liquid chamber of each cylinder from the chip. This requires multiple small and precise cylinders. However, the disadvantage was that the structure was complicated and the manufacturing cost was high.

(c) Disclosure of the invention This invention does not use a cylinder for each injection tip as in the past, but uses a single cylinder to allow each tip to aspirate reagents accurately and evenly, and to accurately and simultaneously discharge the reagents. We propose a simple dispenser that can dispense liquids.

That is, the present invention inserts and fixes a piston cylinder having an air chamber in the lower part inside the container, and communicates the air chamber with a gas provided in the upper part of the housing attached to the lower side of the container via a gas passage. A predetermined number of division air passages are formed inside the division gas, and a number of liquid injection tips corresponding to the number of division air passages are vertically disposed at the bottom of the housing, and a number of liquid injection tips corresponding to the number of division air passages are provided at the bottom of the housing. This invention relates to a dispenser connected via a tube.

Hereinafter, embodiments of the dispenser of the present invention will be described with reference to the drawings.

(d) Embodiment 1 is a cylindrical container that serves as a grip. A cylinder 2 for suctioning and introducing a reagent is inserted and fixed into the container 1, and a piston 3 that protrudes above the cylinder 1 has a portion on its outer periphery. The piston 3, around which the compression coil spring 4 is wound, is always urged upward (that is, in the direction of withdrawal from the cylinder 2).

Furthermore, a sliding body 5 whose head end protrudes outside the vessel body 1 and is capable of vertically sliding upwardly within the vessel body 1 is provided above the piston 3, and whose rotation is restricted.
An operation button 6 is rotatably screwed onto the outer periphery of the head of the button 6. When the button 6 is pressed against the spring 4 to lower the piston 3 and then released, the spring 4 is released. The structure is such that the piston 3 rises due to the force generated, and air is sucked into the air chamber 7 formed in the lower part of the cylinder 2. The reagent will be sucked into the injection tip from the tip).

Further, by rotating the button 6, the sliding body 5 is moved up and down, thereby making it possible to adjust the stroke of the piston 3 (and thus adjust the amount of liquid dispensed).

In addition, in the figure, in order to prevent the sliding body 5 from rotating within the vessel body 1, a longitudinal groove 8 is formed in a part of the sliding body 5 that is in contact with the inner wall of the vessel body 1, and a protrusion provided on the inner wall of the vessel body 1 is formed. Although the child 9 is slidably fitted into the long groove 8, the present invention is not limited thereto.

Reference numeral 10 designates one gas passage that communicates from the air chamber 7 formed below the cylinder 2 to a portion gas 12 to be described later.

11 is a housing attached and fixed to the lower end of the vessel body 1;
As shown in FIG. 2, an upper end port 13 is provided in the upper center of the housing 11 in the attachment portion to the container body 1.
A is in communication with the divided gas 12, and a number of divided air passages 13 corresponding to the number of chips 14 (eight in the figure) to be simultaneously injected into a plurality of test tubes etc. are opened inside the divided gas 12.
is fixed.

Note that the method of communicating the gas passage 10 to each branch air passage 13 includes the lower end opening 10a of the gas passage 10.
A method may be adopted in which a small gap is provided between the upper surface of the partial gas 12 and the upper surface of the partial gas 12 as shown in FIG. As shown in FIG. The upper end ports 13a of each branch air passage must be provided at the same distance from the lower end port 10a of the gas passage and at equal intervals from each other.

Reference numeral 14 denotes a liquid injection tip with a straight inner flow path, which is vertically installed on the bottom plate 11a of the housing 11, and the same number as the above-mentioned division channels 13 are removably installed in parallel.
4 communicates with a connector 15 attached and fixed to a corresponding location of the chip 14 on the upper surface of the bottom plate 11a of the housing through a thin tube 16, and each connector 15 is connected to another connector attached to the lower end port 13b of each of the above-mentioned branch air passages 13. 20 through a tube 17 such as a rubber tube.

Adjustment screws 18 for finely adjusting the amount of liquid to be dispensed are screwed into locations corresponding to each of the capillary tubes 16 on the bottom plate 11a of the housing so that the threaded ends of the screws 18 can be inserted into the capillary tubes 16.
The amount of liquid can be adjusted by adjusting the amount inserted into the thin tube 16 at the end. Note that once the screws 18 are adjusted in advance so that the amount of liquid supplied into each chip 14 is equal, there is no need to adjust them thereafter.

After inserting the tip of the injection tip 14 into the reagent container and adjusting the stroke of the piston 3 by turning the operation button 6, place your finger on the finger hook 19 protruding from the side of the upper end of the container 1 and press it with your thumb. Operation button 6
When pressed down and released, the piston 3 rises to open each of the gas passages 10 and 12.
3 and each injection tip 14 via each tube 17
A predetermined amount of reagent is evenly drawn into the chamber.

Then, when button 6 is pressed again, the air in air chamber 7, gas passage 10, each branch air passage 13, and tube 17 is compressed, and the same amount of reagent is drained from the tip of each tip 14 at the same time. be.

(e) Effects of the invention The dispenser of the invention is constructed as described above, and a single cylinder sucks reagent into each injection tip, distributing the same amount of reagent from the tip to multiple test samples. can be added simultaneously and accurately, making it possible to quickly analyze and measure a large number of samples, greatly reducing time and labor, and eliminating the need to use a cylinder for each injection tip as in the past. Since it is not a physical product, it has various advantages such as a simple structure and low manufacturing cost.

[Brief explanation of drawings]

FIG. 1 is a partially sectional front view showing an example of the dispenser according to the present invention, FIG. 2 is a longitudinal cross-sectional view of the divided gas, and FIG. 3 is a plan view showing another embodiment of the divided gas. Symbol explanation, 1... Vessel, 2... Cylinder, 3...
...Piston, 4...Spring, 5...Sliding body,
6... Operation button, 7... Air chamber, 8... Longitudinal groove, 9... Stem, 10... Gas passage, 11... Housing, 12... Minute gas, 13... Minute air passage, 14... …
Liquid injection tip, 15...connector, 16...tube,
17...tube, 18...adjustment screw, 19...
Finger hook, 20...connector.

Claims (1)

[Scope of Claim for Utility Model Registration] (1) A piston cylinder whose internal lower part forms an air chamber is inserted and fixed into the container, and the air chamber is a gas passage provided at the upper part of the housing attached to the lower side of the container. A predetermined number of divided air passages are formed inside the housing, and a number of liquid injection tips corresponding to the number of divided air passages are vertically disposed at the bottom of the housing. A dispenser characterized in that it is connected to the lower end port of the dividing airway via a tube. (2) The dispenser according to claim 1, wherein the upper end ports of each of the divided gases opening on the upper surface of the divided gas are provided at equal distances from the lower end ports of the gas passages and at equal intervals from each other. (3) The gas passage communicates with the partial gas by leaving a slight gap between the lower end of the gas passage and the upper surface of the partial gas, and communicating with the upper end of each of the partial air openings on the upper surface of the partial gas. A dispenser according to claim 1 or 2 of the utility model registration claim. (4) The gas passage communicates with the partial gas by forming grooves radially from the upper end of each of the partial gas toward the center of the upper surface of the partial gas, so that the lower end of the gas passage is in close contact with the center of the upper surface of the partial gas. A dispenser according to claim 1, 2 or 3 of the claims for utility model registration. (5) In the thin tubes provided in the bottom plate that communicate with each liquid injection tip vertically installed on the bottom plate of the housing, an adjustment screw for finely adjusting the amount of liquid to be dispensed is inserted from outside the bottom plate, and the screw end thereof is inserted into the thin tube. Paragraph 1, 2, 3, or 4 of the claims for utility model registration that can be screwed together
Dispenser as described in section.