JPH0481564B2 - - Google Patents
Info
- Publication number
- JPH0481564B2 JPH0481564B2 JP59169240A JP16924084A JPH0481564B2 JP H0481564 B2 JPH0481564 B2 JP H0481564B2 JP 59169240 A JP59169240 A JP 59169240A JP 16924084 A JP16924084 A JP 16924084A JP H0481564 B2 JPH0481564 B2 JP H0481564B2
- Authority
- JP
- Japan
- Prior art keywords
- hair growth
- ginseng
- bamboo
- hair
- ginseng extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003779 hair growth Effects 0.000 claims description 15
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 10
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 10
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 10
- 239000011425 bamboo Substances 0.000 claims description 10
- 235000008434 ginseng Nutrition 0.000 claims description 8
- 235000020710 ginseng extract Nutrition 0.000 claims description 8
- 241000208340 Araliaceae Species 0.000 claims description 7
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 6
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 6
- 239000007952 growth promoter Substances 0.000 claims description 6
- 244000082204 Phyllostachys viridis Species 0.000 claims 2
- 241001330002 Bambuseae Species 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 239000006071 cream Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000006210 lotion Substances 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 239000008213 purified water Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 240000004371 Panax ginseng Species 0.000 description 2
- 235000002789 Panax ginseng Nutrition 0.000 description 2
- -1 Polyoxyethylene cetyl ether Polymers 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 229940057995 liquid paraffin Drugs 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000168720 Panax japonicus Species 0.000 description 1
- 235000003174 Panax japonicus Nutrition 0.000 description 1
- 241001527087 Panax vietnamensis Species 0.000 description 1
- 235000017726 Panax vietnamensis Nutrition 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007765 cera alba Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Description
【発明の詳細な説明】
本発明は発毛促進剤、更に詳しくは竹節人参又
は竹節人参エキスを含有する発毛促進剤に関す
る。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a hair growth promoter, and more particularly to a hair growth promoter containing bamboo knot ginseng or bamboo knot ginseng extract.
一般に発毛促進剤として使用される物質は優れ
た主目的効果を呈するとともに比較的長期間にわ
たり連用することから、特に安全性が高いことが
要求される。 Substances generally used as hair growth promoters exhibit excellent main effects and are required to be particularly safe since they are used continuously for a relatively long period of time.
本発明者等は、上述の効果を有する物質の探索
研究をなした結果、竹節人参がこの目的にかなう
ことを見出し本発明を完成した。 As a result of searching and researching substances having the above-mentioned effects, the present inventors discovered that bamboo-knotted ginseng satisfies this purpose and completed the present invention.
竹節人参はウコギ科のトチバニンジン
（Panaxjaponicum）の根茎をそのままあるいは
湯通しして乾燥したものをいい滋養強壮剤として
繁用されている朝鮮人参（オタネニンジン：
Panaxginseng）と類似しているが成分のサポニ
ンの種類が異なり、痰、解熱、健胃薬とくに胃
部の熱感および水分停滞感、心か部のつかえの治
療などに用いられている。 Bamboo ginseng is the rhizome of Panax japonicum, a member of the Araliaceae family, that is used as it is or is blanched and dried. Panax ginseng is often used as a nutritional tonic.
Although it is similar to Panaxginseng, it contains different types of saponins, and is used to treat phlegm, reduce fever, and improve the stomach, especially for a feeling of heat and fluid retention in the stomach, and for the treatment of heart congestion.
本発明の優れた発毛効果は竹節人参を検体とし
これを除毛クリームで脱毛したddY系雄性マウス
の腹部に２週間塗布した結果確認した。 The excellent hair growth effect of the present invention was confirmed by using bamboo-knot ginseng as a specimen and applying it to the abdomens of ddY male mice that had been depilated with hair removal cream for two weeks.
即ち、竹節人参塗布群は対照群（アルコール水
溶液のみ）と比較し塗布初期から顕著な発毛がみ
られ投与期間中有意に発毛促進効果が認められ、
新規発毛促進剤として有用なものである。 In other words, in comparison to the control group (alcohol aqueous solution only), the bamboo knot ginseng application group showed remarkable hair growth from the early stage of application, and a significant hair growth promoting effect was observed during the administration period.
It is useful as a new hair growth promoter.
本発明の発毛促進剤の実施に際しては、竹節人
参エキス末を配合したアルコールローシヨン、乳
液、クリーム等の外用剤型のいずれを採用しても
よく、これ等は常法に従つて製することができ
る。 When implementing the hair growth promoter of the present invention, any external dosage form such as alcohol lotion, milky lotion, cream, etc. containing Bamboo Bush Ginseng extract powder may be adopted, and these can be prepared according to conventional methods. be able to.
これら外用剤に含有させる竹節人参エキスの含
量は約0.1％〜10％、好ましくは0.5〜５％が考え
られる。 The content of bamboo knot ginseng extract contained in these external preparations is considered to be about 0.1% to 10%, preferably 0.5 to 5%.
以下、試験例及び処方例をもつて本発明を説明
する。 The present invention will be explained below using test examples and prescription examples.
試験例
竹節人参エキス（日本粉末薬品製、１重量部の
竹節人参を３重量部の50％アルコールを抽出した
もの）を検液する。Test example: Test the sample with Takebushi ginseng extract (manufactured by Nippon Powder Pharmaceutical Co., Ltd., extracted from 1 part by weight of Takebushi ginseng with 3 parts by weight of 50% alcohol).
一方、実験動物としてddY系雄性マウスを選び
その腹部を除毛クリームで脱毛し、脱毛部に検液
を１日１回14日間塗布した。 On the other hand, a male ddY mouse was selected as an experimental animal, and its abdomen was depilated with hair removal cream, and a test solution was applied to the depilated area once a day for 14 days.
発毛促進効果は発毛スコアーを次のように設定
し10匹の平均値を指標として評価した。 The hair growth promoting effect was evaluated by setting the hair growth score as follows and using the average value of 10 animals as an index.
スコアー設定
０ 発毛みられず
１ 発毛している
２ 硬毛がはえそう
３ 硬毛の長さが正常毛の約半分
４ 正常毛の状態
実験結果
図１に示す如く対照群（ｎ＝10）に対し塗布群
（ｎ＝10）は有意に発毛促進効果を呈した。Score setting 0 No hair growth 1 Hair growth 2 Terminal hair seems to be growing 3 Terminal hair length is about half of normal hair 4 Normal hair condition experimental results As shown in Figure 1, control group (n = 10), the application group (n=10) exhibited a significant hair growth promoting effect.
処方例 １ アルコールローシヨン 竹節人参エキス 5.0 95％エタノール 50.0 精製水 45.0 処方例 ２ クリーム 竹節人参エキス 5.0 プロピレングリコール 3.0 サラシミツロウ 3.0 流動パラフイン 40.0 ポリオキシエチレンセチルエーテル 3.0 モノステアリン酸ソルビタン 2.0 精製水 44.0 処方例 ３ 乳液 竹節人参エキス 5.0 ワセリン 3.0 流動パラフイン 10.0 グリセリン 3.0 プロピレングリコール 5.0 ポリオキシエチレンモノオレイン酸エステル 2.0 精製水 72.0Prescription example 1 alcohol lotion Bamboo bush ginseng extract 5.0 95% ethanol 50.0 Purified water 45.0 Prescription example 2 cream Bamboo bush ginseng extract 5.0 Propylene glycol 3.0 White beeswax 3.0 Liquid paraffin 40.0 Polyoxyethylene cetyl ether 3.0 Sorbitan monostearate 2.0 Purified water 44.0 Prescription example 3 emulsion Bamboo bush ginseng extract 5.0 Vaseline 3.0 Liquid paraffin 10.0 glycerin 3.0 Propylene glycol 5.0 Polyoxyethylene monooleate 2.0 Purified water 72.0
図１は本発明物質の発毛効果を経時的に示した
ものであり、実線は塗布群のスコアーの平均値を
示し、点線は対照群のスコアーの平均値を示す。
FIG. 1 shows the hair growth effect of the substance of the present invention over time, where the solid line shows the average score of the applied group, and the dotted line shows the average score of the control group.
Claims (1)
促進剤。1. A hair growth promoter containing bamboo knot ginseng or bamboo knot ginseng extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59169240A JPS6147411A (en) | 1984-08-15 | 1984-08-15 | Promoter for hair growth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59169240A JPS6147411A (en) | 1984-08-15 | 1984-08-15 | Promoter for hair growth |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6147411A JPS6147411A (en) | 1986-03-07 |
| JPH0481564B2 true JPH0481564B2 (en) | 1992-12-24 |
Family
ID=15882836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59169240A Granted JPS6147411A (en) | 1984-08-15 | 1984-08-15 | Promoter for hair growth |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6147411A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2655646B2 (en) * | 1987-06-26 | 1997-09-24 | 株式会社 ビタミン研究所 | Androgen receptor binding inhibitor |
| JPH08253410A (en) * | 1991-04-11 | 1996-10-01 | Masaharu Iwasaki | Hair grower |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5391109A (en) * | 1977-01-20 | 1978-08-10 | Koshiro Chiyuuji Shiyouten Kk | Antitumor agent |
| FI56434C (en) * | 1978-04-27 | 1980-01-10 | Hunt & Moscrop | MECHANICAL DRIVING ORGANIZATION IN PAO EN FAST AXEL LAGRAD ROTERBAR MANTEL I SYNNERHET EN MANTEL PAO EN BOEJNINGSKOMPENSERAD VALS FOER EN PAPPERSMASKIN |
| IT7824224A0 (en) * | 1978-06-05 | 1978-06-05 | Snia Viscosa | FORMULATION SUITABLE TO FACILITATE THE COTTON-TYPE SPINNING OF STRONGLY CURLED CELLULOSIC FIBERS. |
-
1984
- 1984-08-15 JP JP59169240A patent/JPS6147411A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6147411A (en) | 1986-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |