JPH0529337B2 - - Google Patents

Info

Publication number: JPH0529337B2
Authority: JP; Japan
Prior art keywords: glutaraldehyde; solution; aqueous solution; aqueous; sodium
Prior art date: 1986-10-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP25531386A

Other languages

English (en)

Japanese (ja)

Other versions

JPS63112532A (ja

Inventor

Nobukatsu Sato

Toshio Tajima

Urao Kawakami

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Maruishi Pharmaceutical Co Ltd

Original Assignee

Maruishi Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-27

Filing date

1986-10-27

Publication date

1993-04-30

1986-10-27 Application filed by Maruishi Pharmaceutical Co Ltd filed Critical Maruishi Pharmaceutical Co Ltd

1986-10-27 Priority to JP25531386A priority Critical patent/JPS63112532A/ja

1988-05-17 Publication of JPS63112532A publication Critical patent/JPS63112532A/ja

1993-04-30 Publication of JPH0529337B2 publication Critical patent/JPH0529337B2/ja

Status Granted legal-status Critical Current

Links

SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 34
239000007864 aqueous solution Substances 0.000 description 32
239000000243 solution Substances 0.000 description 17
GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 14
239000003381 stabilizer Substances 0.000 description 14
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 12
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 12
238000000034 method Methods 0.000 description 11
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 10
238000001556 precipitation Methods 0.000 description 9
HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 9
229940001584 sodium metabisulfite Drugs 0.000 description 9
235000010262 sodium metabisulphite Nutrition 0.000 description 9
235000010265 sodium sulphite Nutrition 0.000 description 7
239000000126 substance Substances 0.000 description 7
230000000844 anti-bacterial effect Effects 0.000 description 6
229940079877 pyrogallol Drugs 0.000 description 6
239000012488 sample solution Substances 0.000 description 6
VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
229910000030 sodium bicarbonate Inorganic materials 0.000 description 6
235000017557 sodium bicarbonate Nutrition 0.000 description 6
239000004471 Glycine Substances 0.000 description 5
230000002265 prevention Effects 0.000 description 5
238000000746 purification Methods 0.000 description 5
239000012085 test solution Substances 0.000 description 5
239000011521 glass Substances 0.000 description 4
239000000377 silicon dioxide Substances 0.000 description 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
239000003463 adsorbent Substances 0.000 description 3
125000003172 aldehyde group Chemical group 0.000 description 3
239000013068 control sample Substances 0.000 description 3
230000007423 decrease Effects 0.000 description 3
230000000694 effects Effects 0.000 description 3
-1 longalite Chemical compound 0.000 description 3
239000007790 solid phase Substances 0.000 description 3
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
241000588724 Escherichia coli Species 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 description 2
241000589517 Pseudomonas aeruginosa Species 0.000 description 2
241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 2
DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 2
241000191967 Staphylococcus aureus Species 0.000 description 2
125000000217 alkyl group Chemical group 0.000 description 2
125000003277 amino group Chemical group 0.000 description 2
125000004432 carbon atom Chemical group C* 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
239000000645 desinfectant Substances 0.000 description 2
GRWZHXKQBITJKP-UHFFFAOYSA-L dithionite(2-) Chemical compound [O-]S(=O)S([O-])=O GRWZHXKQBITJKP-UHFFFAOYSA-L 0.000 description 2
229960002449 glycine Drugs 0.000 description 2
125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
239000000203 mixture Substances 0.000 description 2
235000010267 sodium hydrogen sulphite Nutrition 0.000 description 2
229940001482 sodium sulfite Drugs 0.000 description 2
239000007787 solid Substances 0.000 description 2
238000001179 sorption measurement Methods 0.000 description 2
230000001954 sterilising effect Effects 0.000 description 2
238000004659 sterilization and disinfection Methods 0.000 description 2
LCPVQAHEFVXVKT-UHFFFAOYSA-N 2-(2,4-difluorophenoxy)pyridin-3-amine Chemical compound NC1=CC=CN=C1OC1=CC=C(F)C=C1F LCPVQAHEFVXVKT-UHFFFAOYSA-N 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
206010011409 Cross infection Diseases 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
239000004372 Polyvinyl alcohol Substances 0.000 description 1
206010040047 Sepsis Diseases 0.000 description 1
LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical group OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
241000700605 Viruses Species 0.000 description 1
VLSOAXRVHARBEQ-UHFFFAOYSA-N [4-fluoro-2-(hydroxymethyl)phenyl]methanol Chemical compound OCC1=CC=C(F)C=C1CO VLSOAXRVHARBEQ-UHFFFAOYSA-N 0.000 description 1
235000010323 ascorbic acid Nutrition 0.000 description 1
229960005070 ascorbic acid Drugs 0.000 description 1
239000011668 ascorbic acid Substances 0.000 description 1
235000003704 aspartic acid Nutrition 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
210000004666 bacterial spore Anatomy 0.000 description 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
230000001588 bifunctional effect Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
239000003431 cross linking reagent Substances 0.000 description 1
208000002672 hepatitis B Diseases 0.000 description 1
239000010985 leather Substances 0.000 description 1
239000007788 liquid Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
238000000691 measurement method Methods 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
229940068984 polyvinyl alcohol Drugs 0.000 description 1
239000000843 powder Substances 0.000 description 1
235000018102 proteins Nutrition 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
239000002994 raw material Substances 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
XWGJFPHUCFXLBL-UHFFFAOYSA-M rongalite Chemical compound [Na+].OCS([O-])=O XWGJFPHUCFXLBL-UHFFFAOYSA-M 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
229940087377 sodium bicarbonate 300 mg Drugs 0.000 description 1
CHQMHPLRPQMAMX-UHFFFAOYSA-L sodium persulfate Substances [Na+].[Na+].[O-]S(=O)(=O)OOS([O-])(=O)=O CHQMHPLRPQMAMX-UHFFFAOYSA-L 0.000 description 1
230000000007 visual effect Effects 0.000 description 1
238000005406 washing Methods 0.000 description 1
239000003021 water soluble solvent Substances 0.000 description 1

Landscapes

Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

JP25531386A 1986-10-27 1986-10-27 グルタ−ルアルデヒド水溶液の濁りもしくは沈澱防止方法 Granted JPS63112532A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP25531386A JPS63112532A (ja)	1986-10-27	1986-10-27	グルタ−ルアルデヒド水溶液の濁りもしくは沈澱防止方法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP25531386A JPS63112532A (ja)	1986-10-27	1986-10-27	グルタ−ルアルデヒド水溶液の濁りもしくは沈澱防止方法

Publications (2)

Publication Number	Publication Date
JPS63112532A JPS63112532A (ja)	1988-05-17
JPH0529337B2 true JPH0529337B2 (de)	1993-04-30

Family

ID=17277042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP25531386A Granted JPS63112532A (ja)	1986-10-27	1986-10-27	グルタ−ルアルデヒド水溶液の濁りもしくは沈澱防止方法

Country Status (1)

Country	Link
JP (1)	JPS63112532A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7129210B2 (en)	2003-07-23	2006-10-31	Covalent Medical, Inc.	Tissue adhesive sealant
JP4797902B2 (ja) *	2006-09-13	2011-10-19	三浦工業株式会社	鉄の定量方法

1986
- 1986-10-27 JP JP25531386A patent/JPS63112532A/ja active Granted

Also Published As

Publication number	Publication date
JPS63112532A (ja)	1988-05-17

Legal Events

Date	Code	Title	Description
2004-03-09	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2005-03-08	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2006-03-28	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2006-10-27	EXPY	Cancellation because of completion of term

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