JPH0586380B2 - - Google Patents

Info

Publication number
JPH0586380B2
JPH0586380B2 JP8590744A JP9074485A JPH0586380B2 JP H0586380 B2 JPH0586380 B2 JP H0586380B2 JP 8590744 A JP8590744 A JP 8590744A JP 9074485 A JP9074485 A JP 9074485A JP H0586380 B2 JPH0586380 B2 JP H0586380B2
Authority
JP
Japan
Prior art keywords
paramagnetic
contrast agent
agent according
vesicles
vesicle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP8590744A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60252429A (ja
Inventor
Ronald Carl Gamble
Paul Gardner Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Vestar Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Research Inc filed Critical Vestar Research Inc
Publication of JPS60252429A publication Critical patent/JPS60252429A/ja
Publication of JPH0586380B2 publication Critical patent/JPH0586380B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
JP60090744A 1984-04-27 1985-04-26 Ｎｍｒイメージング用造影剤 Granted JPS60252429A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60472184A 1984-04-27 1984-04-27
US604721 1984-04-27
US720954 1985-04-10

Publications (2)

Publication Number Publication Date
JPS60252429A JPS60252429A (ja) 1985-12-13
JPH0586380B2 true JPH0586380B2 (fr) 1993-12-10

Family

ID=24420749

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60090744A Granted JPS60252429A (ja) 1984-04-27 1985-04-26 Ｎｍｒイメージング用造影剤

Country Status (2)

Country Link
JP (1) JPS60252429A (fr)
ZA (1) ZA852979B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2207808C2 (ru) * 1998-04-09 2003-07-10 Амершем Хелт АС Применение контрастных агентов в форме частиц в диагностической визуализации для изучения физиологических параметров
US6869591B2 (en) * 2002-03-26 2005-03-22 Barnes-Jewish Hospital Paramagnetic particles that provide improved relaxivity
EP1926425B1 (fr) 2005-09-13 2015-08-19 Philips Intellectual Property & Standards GmbH Injection multiple d'agent de contraste pour la formation d'images

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192859A (en) * 1978-09-29 1980-03-11 E. R. Squibb & Sons, Inc. Contrast media containing liposomes as carriers
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
FR2550449B1 (fr) * 1983-08-12 1986-01-31 Commissariat Energie Atomique Agents de relaxation specifiques d'organes ou de pathologies, utilisables pour modifier les contrastes en imagerie medicale par resonance magnetique nucleaire
JPS60179052A (ja) * 1983-08-25 1985-09-12 テクニケア・コ−ポレイシヨン 生体組織の核磁気共鳴画像を増強する方法

Also Published As

Publication number Publication date
JPS60252429A (ja) 1985-12-13
ZA852979B (en) 1985-11-27

Similar Documents

Publication Publication Date Title
KR920010391B1 (ko) 핵자기 공명 조영제의 제조 방법
Abou et al. 89Zr-labeled paramagnetic octreotide-liposomes for PET-MR imaging of cancer
US6426058B1 (en) Enhancement of NMR and MRI in the presence of hyperpolarized noble gases
US7769423B2 (en) MRI imageable liposomes for the evaluation of treatment efficacy, thermal distribution, and demonstration of dose painting
US5624662A (en) Liposoluble heterocyclic compounds useful as magnetic resonance imaging agents
Weissig et al. Long-circulating gadolinium-loaded liposomes: potential use for magnetic resonance imaging of the blood pool
CN1269015A (zh) 使用体外极化磁共振成像剂的奥氏磁共振成像方法
JPH04501723A (ja) リポソーム性放射線造影剤
US7672704B2 (en) Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
AU3944893A (en) Methods and compositions for magnetic resonance imaging
Cittadino et al. In vivo magnetic resonance imaging detection of paramagnetic liposomes loaded with amphiphilic Gadolinium (III) complexes: impact of molecular structure on relaxivity and excretion efficiency
WO1998044910A1 (fr) NOUVELLE TECHNIQUE DE CONTROLE DE L'ADMINISTRATION DE MEDICAMENTS NON VULNERANTE $i(IN VIVO)
Ferrauto et al. Detection of U-87 tumor cells by RGD-functionalized/Gd-containing giant unilamellar vesicles in magnetization transfer contrast magnetic resonance images
JP2003530927A (ja) 超分極化造影剤を用いた温度またはｐＨ値の生体内測定のためのＭＲ法
US4859450A (en) Method of NMR imaging using antibody to cardiac myosin
WO1996010359A1 (fr) Complexe de chelates a perceptibilite elevee pour l'imagerie par resonance magnetique
JPH0586380B2 (fr)
Miller et al. Shift-reagent-aided 23Na NMR spectroscopy in cellular, tissue, and whole-organ systems
CA2652264C (fr) Agent de contraste pour resonance magnetique contenant du polyethylene-glycol et procede de d'acquisition d'images par resonance magnetique
Dias et al. Contrast agents for nuclear magnetic resonance imaging
Pereira et al. Design and optimization of gadolinium based contrast agents for magnetic resonance imaging
Wijesekera Evaluating Hypoxia-Targeting Vectors for MRI Applications
Laurent et al. Lanthanides: Magnetic Resonance Imaging
Huang Magnetic resonance imaging: contrast enhancement of brain tumor pathology through chemical intervention
Aime et al. Recent Developments of Contrast Agents, CEST and Low Fields

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term