JPH06296660A - Blood bag set - Google Patents

Abstract

(57) [Summary] [Structure] The parent bag 1 from which whole blood is collected is provided with upper layer / lower layer connecting portions 10 and 11, and the lower end portion of the upper layer connecting portion 10 is a parent. The upper portion of the bag 1 main body 8 is opened, and the lower end portion of the lower layer connecting portion 11 is opened at the upper end portion of the narrow portion 16 of the parent bag 1. When the whole blood inside the parent bag 1 is centrifuged, the parent bag 1 is squeezed, and the plasma in the upper layer inside the parent bag 1 passes through the upper layer connecting portion 10 and the upper layer tube 6 to form the upper layer. The blood components, mainly red blood cells, in the lower layer inside the parent bag 1 are transferred to the child bag 4 through the lower layer connecting portion 11 and the lower layer tube 7 to the lower layer child bag 5. To be done. [Effect] When the blood bag set is applied to the centrifuge, it is difficult to form protrusions on the parent bag 1 and the parent bag 1 is not easily formed.
Is less likely to be damaged by the protrusion.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood bag set used for separating blood into individual components.

[0002]

2. Description of the Related Art A blood bag set is used for taking out various blood components contained in whole blood and formulating them.

As a blood bag set, Japanese Patent Publication No. 63-
There is one shown in Japanese Patent Publication No. 20144, in which an upper layer connecting portion is provided at an upper end portion of a parent bag from which whole blood is collected, and a lower layer connecting portion is provided at a lower end portion of the parent bag.
An upper layer child bag and a lower layer child bag are connected to the upper layer connecting portion and the lower layer connecting portion via the upper layer tube and the lower layer tube, respectively.

When separating the whole blood collected in the parent bag into blood components, the whole blood bag set is placed in a centrifuge and the whole blood in the parent bag is centrifuged. As a result, an upper layer called plasma is formed in the upper portion of the parent bag, and an intermediate layer (hereinafter, referred to as buffy coat) that mainly contains white blood cells and forms a thin layer is formed in the inner portion of the parent bag. A lower layer mainly containing red blood cells is separately formed in the lower portion. Next, the parent bag is squeezed by a blood separation squeezing device, and each component of blood in the upper and lower parts inside the parent bag is passed through each connection part and each tube, and the upper layer child bag and the lower layer child. Simultaneously transferred to the bag. As a result, the buffy coat remains on the parent bug.

The above blood bag set is very advantageous in terms of labor saving and shortening of working time because the blood components in the upper part and the lower part inside the parent bag can be simultaneously transferred to the two child bags.

When centrifuging a blood bag set with a centrifuge, the blood bag set is set in the centrifuge device so that the tube does not come into contact with each bag.

[0007]

However, in the above blood bag set, since the lower layer connecting portion is provided at the lower end portion of the parent bag, and the lower layer tube is connected to this connecting portion, the blood bag set is formed. When set in the centrifuge, the lower layer tube is apt to be set in contact with the upper and lower side surfaces of the parent bag.

[0008] When set in this way, when centrifuged, the side surface of the parent bag is strongly pressed against the outer lower-layer tube, and the periphery of the pressed portion of the parent bag swells to form a protrusion. Is easily formed, and particularly in the lower part of the parent bag, a large gravitational acceleration acts during centrifugation, so that a protrusion is easily formed.

When the protrusion is formed as described above, the parent bag is easily damaged by the protrusion, and there has been a problem how to solve this problem. The present invention solves the above problems, and an object of the present invention is to provide a blood bag set in which the parent bag is less likely to be damaged by the protrusion, that is, the protrusion is less likely to occur.

[0010]

According to the present invention, an upper layer child bag and a lower layer child bag are respectively formed on a parent bag composed of two synthetic resin sheets from which whole blood is collected. The whole blood inside the parent bag, which is connected via the layer connection part and the lower layer connection part, is centrifuged into an upper layer containing plasma, an intermediate layer containing white blood cells, and a lower layer containing red blood cells. Then, the upper layer, via the connection portion for the upper layer,
In the upper layer child bag, and the lower layer is transferred to the lower layer child bag via the lower layer connecting portion,

By fusing the sheets forming the bag, the inside of the parent bag is partitioned in the vertical direction at the upper part of the parent bag and along the edge of the bag so that the main bag main body and the parent bag are lowered downward. An open narrow portion is provided, and the open portion is located in the upper layer after the centrifugation, and
It shall be located in the lower layer after the transfer of the upper layer,

An upper layer connecting portion and a lower layer connecting portion are provided on an upper portion of the parent bag, the upper layer connecting portion opens at an upper portion inside the parent bag, and the lower layer connecting portion has the parent bag narrow portion. The main point is a blood bag set that is open at the upper end inside.

In the present invention, whole blood is blood collected from a human body before being subjected to a blood component separation operation.

In the present invention, the size of the narrow portion provided by partitioning the inside of the parent bag is such that the cross-sectional area of the narrow portion when blood is contained is approximately the same as the cross-sectional area of the inside of the tube used for the blood bag set. is there.

[0015]

[Function] When whole blood is collected and centrifuged, the whole blood is first introduced into the parent bag. Next, the blood bag set is placed in a centrifuge and the blood inside the parent bag is centrifuged, and an upper layer of plasma is present in the upper part inside the parent bag.
A buffy coat is formed separately in the middle part inside the parent bag, and a lower layer mainly containing red blood cells is formed separately in the lower part inside the parent bag.

At this time, since the lower end portion of the parent bag is not provided with the lower layer connecting portion or the lower layer tube is connected to the connecting portion as in the conventional case, the blood bag set is separated by the centrifugal separator. When being set, the lower layer tube is less likely to be set in contact with the side surface of the parent bag.

Then, after centrifuging the whole blood, the parent bag is compressed and the blood component in the upper part inside the parent bag is passed through the upper layer connecting portion and the upper layer tube to the upper layer child bag. Transfer.

After transferring the blood component of the upper portion, the buffy coat and the lower layer remain inside the parent bag, but the open portion of the narrow portion is at a position lower than the buffy coat at this time, and the lower portion mainly containing red blood cells. Located in a layer.

Next, the parent bag is squeezed in the same manner as above, and the blood component of the lower layer inside the parent bag is transferred to the lower layer child bag through the lower layer connecting portion and the lower layer tube. As a result, the buffy coat remains on the parent bug.

In the above case, when whole blood is introduced into the parent bag, whole blood also enters the narrow portion, but the open portion of the narrow portion is located in the upper layer which is plasma after centrifugation and is buffy coat. Since it is located higher than the above, it is a feature of the present invention that the buffy coat rarely enters the narrow portion when the separation operation is performed as described above.

[0021]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawing of FIG. FIG. 1 shows a blood bag set having a parent bag 1, a blood collection needle 3 with a blood collection tube 2, upper and lower layer child bags 4, 5, and upper and lower layer tubes 6, 7 and the like. .

The parent bag 1 is for collecting whole blood and is mainly composed of a main body 8. The main body 8 is composed of two sheets made of synthetic resin such as polyvinyl chloride, and the periphery of these sheets. Are bonded by heat fusion or high frequency welding. The upper end of the main body 8 is provided with a connecting portion 9 to which the blood collecting tube 2 is connected, upper layer / lower layer connecting portions 10 and 11 and a blood transfusion port 13 with a protector 12.

By partitioning the inside of the parent bag in the vertical direction by fusion bonding, a narrow portion 16 having an open portion 17 is provided between the parent bag and the edge of the parent bag.

The upper layer / lower layer connecting portions 10 and 11 are
In the embodiment, for example, the flexible tube is made of a synthetic resin such as polyvinyl chloride, and is sandwiched and fixed between the two sheets of the main body 8 when they are bonded. The upper portions of the upper-layer / lower-layer connecting portions 10 and 11 project above the main body 8 and the upper portion of the connecting portions 10 and 11 are connected to each other by bending them so that the inside and the outside of the main body 8 communicate with each other. 14) and 15 are provided. The lower end of the upper layer connecting portion 10 opens at the upper end inside the main body 8, and the lower end of the lower layer connecting portion 11 opens at the upper end inside the narrow portion 16.

Inside the main body 8, CPD liquid, ACD-
A blood preservation solution such as A solution may be enclosed.

The upper layer / lower layer child bags 4 and 5 are bags for transferring and storing the respective blood components in the upper and lower parts of the body 8 respectively, and are used to store them. It is connected to the layer connecting portions 10 and 11 via upper layer / lower layer tubes 6 and 7.

According to the embodiment configured as described above, when whole blood is collected and centrifuged, the whole blood is first collected from the blood donor by the blood collection needle 3 through the blood collection tube 2 and the connecting portion 9. Is introduced into the main body 8 of the parent bag 1.

When the blood bag set is put in a centrifuge and the blood in the body 8 is centrifuged at 4000 rpm, the upper layer of plasma is in the upper portion of the body 8, the buffy coat is in the middle portion, and the red blood cells are in the lower portion. The lower layers containing mainly are separately formed.

At this time, since the lower layer connecting portion is not provided at the lower end of the parent bag 1 and the lower layer tube is not connected to the connecting portion, when the blood bag set is set in the centrifugal separator, The layer tube 7 is less likely to be set in contact with the side surface of the main body 8 of the parent bag 1.
Therefore, as in the prior art, the main body 8 of the parent bag 1 is strongly pressed against the lower layer tube 7 during centrifugation, and the periphery of the pressed portion of the main body 8 swells to form a protrusion,
The main body 8 is less likely to be damaged by the protrusion.

After centrifuging the whole blood as described above, the end of the blood collecting tube 2 on the side of the connecting portion 9 is blocked, and then the communicating pieces 14 and 15 are bent to connect the upper and lower layers. Through the parts 10 and 11 and the upper and lower layer tubes 6 and 7, for the inside of the main body 8 of the parent bag 1 and the upper layer,
The lower layer child tags 4 and 5 are communicated with each other. Then, the main body 8 of the parent bag 1 is compressed by, for example, a blood separation squeezing device, and the blood component in the upper part of the main body 8, that is, plasma, is passed through the upper layer connecting portion 10 and the upper layer tube 6. , And transferred to the upper layer child bag 4.

After that, the blood component in the lower portion inside the main body 8 is transferred to the lower layer child bag 5 through the lower layer connecting portion 11 and the lower layer tube 7. In the example,
Although the connecting portions for the upper layer and the lower layer are formed by the tubes, these connecting portions may be integrally formed on the main body of the parent bag, and each of these connecting portions is connected to the tube for the upper layer and the lower layer. You may integrate each. Further, in the embodiment, each of the upper layer / lower layer connecting portions is applied to one, but a plurality of connecting portions may be applied.

[0032]

As described in detail above, according to the present invention,
In the work of extracting blood components from whole blood, when the blood bag set is subjected to a centrifuge, the parent bag is less likely to have a protrusion, and the parent bag is less likely to be damaged by the protrusion. Further, according to the present invention, a good blood product can be obtained.

[Brief description of drawings]

FIG. 1 is a front view of a blood bag set showing an embodiment of the present invention.

[Explanation of symbols]

 1 parent bag 4 upper layer child bag 5 lower layer child bag 6 upper layer tube 7 lower layer tube 8 main body 10 upper layer connecting portion 11 lower layer connecting portion

Claims (1)

[Claims] 1. A parent bag composed of two sheets of synthetic resin for collecting whole blood, a child bag for the upper layer and a child bag for the lower layer, respectively, for a connecting portion for the upper layer and for the lower layer. Connected via a connection, whole blood inside the parent bag is centrifuged into an upper layer containing plasma, an intermediate layer containing white blood cells, and a lower layer containing red blood cells, the upper layer being A sheet forming a bag in which the lower layer is transferred to the upper layer child bag through the upper layer connecting portion, and the lower layer is transferred to the lower layer child bag through the lower layer connecting portion. By fusing, the upper part of the parent bag and along the edge of the bag, the inside of the parent bag is partitioned in the vertical direction to provide a narrow portion that is opened downward in the parent bag in addition to the main bag body. And the opening is located in the upper layer after the centrifugation. In addition, after the transfer of the upper layer, it shall be located in the above lower layer, the upper layer connecting portion for the upper layer and the connecting portion for the lower layer are provided on the upper portion of the parent bag, and the connecting portion for the upper layer is the upper portion inside the parent bag. The blood bag set is characterized in that the lower layer connection portion is opened at the upper end portion inside the parent bag narrow portion.