JPH06329532A - Water-in-oil aerosol composition and production process thereof - Google Patents

Abstract

PURPOSE:To provide a water-in-oil type aerosol composition which has excellent storage stability and affinity to skins and hairs and gives clean and neat feeling, when applied and a production process thereof. CONSTITUTION:The water-in-oil type aerosol composition comprises (A) 50 to 97wt.% component concentrate containing (i) 3 to 50wt.% lipid component, (ii) 0.05 to 10wt.% nonionic surface active agent, and (iii) 50 to 95wt.% aqueous component and (B) 3 to 50wt.% liquefied gas and the production process thereof.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a water-in-oil type aerosol composition and a method for producing the same. More specifically, it has excellent storage stability and affinity for skin and hair, and gives a refreshing feeling of use, for example, cosmetics, quasi-drugs, water-in-oil type aerosol compositions which can be suitably used for pharmaceuticals, And a method for easily producing the composition without requiring complicated production steps.

[0002]

2. Description of the Related Art Conventionally, as an aerosol composition used for, for example, a cream for skin or hair, it is known that a water-in-oil type aerosol composition is excellent in terms of protection of skin and hair. .

However, in order to prepare the undiluted solution of the water-in-oil type aerosol composition, it is necessary to heat each component and to stir them with, for example, a homomixer, so that the operation is very complicated. . In addition, even if the formulation and manufacturing conditions are sufficiently designed, during mass production, the resulting undiluted solution of the water-in-oil type aerosol composition may vary, which makes management difficult, or When the water content is increased in order to reduce stickiness during use, there is a problem that the viscosity of the stock solution increases, the emulsifying property becomes poor, and layer separation easily occurs.

[0004]

Therefore, as a result of intensive studies conducted by the present inventors in view of the above-mentioned prior art, an oil having a specific blending ratio in which a specific surfactant is blended in at least one of them is obtained. When using a stock solution obtained by mixing a water component and a water component, a water-in-oil type aerosol composition having excellent storage stability and affinity for skin, hair, etc., and giving a refreshing feeling is obtained. They have found that they can be easily obtained, and have completed the present invention.

[0005]

That is, the present invention is
An undiluted solution containing 3 to 50% by weight of an oil component, 0.05 to 10% by weight of a nonionic surfactant, and 50 to 95% by weight of a water component.
Water-in-oil type aerosol composition consisting of 97% by weight and liquefied gas 3 to 50% by weight, and 3 to 50% by weight of oil component and 0.05 to 10% by weight of nonionic surfactant relative to the stock solution. Prepare a stock solution by mixing with 50-95% by weight of water component,
50 to 97% by weight of the stock solution and 3 to 50% by weight of liquefied gas are mixed to prepare a water-in-oil type aerosol composition and the stock solution. A stock solution is prepared by mixing 95% by weight of a water component and 0.05-10% by weight of a nonionic surfactant, and 50-97% by weight of the stock solution and 3-50% by weight of a liquefied gas are mixed. The present invention relates to a method for producing a water-in-oil type aerosol composition which is characterized.

[0006]

Actions and Examples As described above, the water-in-oil type aerosol composition of the present invention comprises 3 to 50% by weight of an oil component, 0.05 to 10% by weight of a nonionic surfactant and 50 to 95% by weight of a water component.
It is composed of 50 to 97% by weight of a stock solution containing 3 to 50% by weight of liquefied gas.

The oil component used in the undiluted solution is a component for imparting penetrability and luster to skin and hair, protecting it to maintain its healthy state and improving extensibility. It is not particularly limited as long as it can be used for, but it is at least one selected from hydrocarbons, vegetable oils, animal oils and fatty acid esters because it is liquid at room temperature and is intended for the human body. Preferably there is.

Specific examples of the oil component include, for example, liquid paraffin such as Isopar A, Isopar C,
Isoparaffinic hydrocarbons such as Isopar D, Isopar E, Isopar G, Isopar H, Isopar K, Isopar L, Isopar M (above, exon),
Hydrocarbons such as petrolatum, squalane, α-olefin oligomer, squalene; olive oil, almond oil, jojoba oil, peanut oil, castor oil, coconut oil, palm oil, safflower oil, sunflower oil, cottonseed oil, avocado oil,
Camellia oil, corn oil, wheat germ oil, rice bran oil,
Cocoa butter, sesame oil, evening primrose oil, safflower oil, southern oil, soybean oil, rapeseed oil and other vegetable oils; lanolin, lanolin derivatives, turtle oil, mink oil, beeswax, pristane, egg yolk oil and other animal oils; butyl stearate, hexyl laurel Examples thereof include fatty acid esters such as rate, isopropyl myristate, octyldodecyl myristate, isopropyl palmitate, diisopropyl adipate, and diisopropyl sebacate, and these can be used alone or in admixture of two or more.

The mixing ratio of the oil component to the stock solution is 3 to 50.
%, Preferably 5-40% by weight. When the blending ratio of such an oil component is less than 3% by weight, the water-in-oil type aerosol composition to be obtained becomes poor in elongation, and when it exceeds 50% by weight, the water-in-oil composition is increased. The type aerosol composition becomes sticky.

The nonionic surfactant used in the undiluted solution is a component which acts as an emulsifier for obtaining a water-in-oil type aerosol composition.

Specific examples of the nonionic surfactant include polyglycerin fatty acid ester, decaglycerin fatty acid ester, diglycerin fatty acid ester, and the like.
Monoglycerin fatty acid ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester,
Ester type nonionic surfactants such as polyoxyethylene sorbit fatty acid ester, polyoxyethylene lanolin, polyethylene glycol fatty acid ester, sucrose fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene Examples include ether type nonionic surfactants such as alkyl phenyl ether, and ether ester type nonionic surfactants such as polyoxyethylene castor oil and polyoxyethylene hydrogenated castor oil. These may be used alone or in combination of two or more. Among these, the emulsifying power can be increased even if the mixing ratio of the water component described below is increased in order to reduce the stickiness of the obtained water-in-oil type aerosol composition. Is hard to fall Preferably ester type nonionic surface active agents in terms of, in particular the polyglycerol fatty acid ester is preferable.

The blending ratio of the nonionic surfactant to the stock solution is 0.05 to 10% by weight, preferably 0.1 to 7% by weight. When the blending ratio of the nonionic surfactant is less than 0.05% by weight, the emulsifying power becomes insufficient and phase separation occurs, so that the desired water-in-oil type aerosol composition cannot be obtained. When it exceeds 10% by weight, the surfactant itself becomes too sticky, and the water-in-oil type aerosol composition becomes sticky.

The water component used in the undiluted solution is a component for making the obtained water-in-oil type aerosol composition have a refreshing feeling of use, and the water component is not particularly limited, and is usually an aerosol. Purified water such as distilled water or ion-exchanged water used for the composition can be used.

The mixing ratio of the water component to the stock solution is 50 to 95.
%, Preferably 40-90% by weight. When the blending ratio of the water component is less than 50% by weight, the refreshing feeling of the obtained water-in-oil type aerosol composition is deteriorated, and when it exceeds 95% by weight. ,
The blending amount of the other components such as the oil component and the nonionic surfactant becomes small, and the desired water-in-oil type aerosol composition cannot be obtained.

The stock solution used in the present invention is prepared by mixing an oil component, a nonionic surfactant, and a water component, each of which is adjusted to have a desired amount within the above range.

In the present invention, in the preparation of such a stock solution, the nonionic surfactant is blended with either the oil component or the water component, and then the oil component and the water component are mixed. Alternatively, the oil component and the water component may be mixed after being mixed with both the oil component and the water component.

As described above, the stock solution used in the present invention contains an oil component, a nonionic surfactant and a water component. In addition to these, for example, indomethacin, bufexamac, ketoprofen. , Dexamethasone, sulfur, tolnaftate, silica microbeads, lipophilic powders such as powders obtained by subjecting zinc oxide to a silicone treatment; monohydric alcohols such as ethanol and isopropanol, ethylene glycol, diethylene glycol, triethylene glycol, propylene glycol, glycerin , Alcohols such as polyhydric alcohols such as 1,3-butylene glycol; acetic acid-d
l-α-tocopherol, azulene, l-menthol,
pharmacologically active substances such as dl-camphor; active ingredients; fragrances;
Antiseptics such as parabenzoic acid esters such as methylparaben; Antioxidants such as dibutylhydroxytoluene; UV absorbers such as octyl paradimethylaminobenzoate and octyl methoxycinnamate, for example, cosmetics, quasi drugs, pharmaceuticals, etc. The components usually used in the above can be appropriately selected and blended depending on the application within a range not impairing the object of the present invention. These components may be blended with only one of the oil component and the water component when preparing a stock solution, or may be blended with both components, and there is no particular limitation.

In the present invention, from the viewpoint that the dispersibility is further improved and a water-in-oil type aerosol composition in which agglomeration hardly occurs, the lipophilic powder is contained in an amount of 30% by weight or less based on the stock solution. Especially, it is preferable to mix within the range of 1 to 15% by weight. When the blending ratio of the lipophilic powder is more than 30% by weight, when the obtained water-in-oil type aerosol composition is used as an aerosol product, there is a tendency that clogging may occur in a valve or the like. is there.

Examples of the liquefied gas used as the propellant in the present invention include liquefied petroleum gas containing propane, i-butane and n-butane as main components, dimethyl ether,
Examples thereof include hydrofluorocarbons such as difluoromonochloroethane, monochlorodifluoromethane, and tetrafluoroethane. These can be used alone or in admixture of two or more. Among them, the emulsifying property is excellent and the objective is Liquefied petroleum gas is preferable from the viewpoint that a water-in-oil type aerosol composition can be easily obtained.

The water-in-oil type aerosol composition of the present invention can be obtained by mixing the above-mentioned stock solution and the liquefied gas and gently shaking.

The mixing ratio of the stock solution and the liquefied gas is as follows.
50 to 97% by weight, preferably 60 to 95% by weight, ie 3 to 50% by weight of liquefied gas, preferably 5 to 40% by weight. If the blending ratio of such a stock solution is less than 50% by weight, that is, if the blending ratio of the liquefied gas exceeds 50% by weight, the resulting water-in-oil type aerosol composition may be easily scattered, The amount of the composition deposited on the propellant will decrease, and if the mixture ratio of the undiluted liquid exceeds 97% by weight, that is, if the mixture ratio of liquefied gas is less than 3% by weight, the injection force will be small. , It becomes difficult to perform the function as an aerosol composition.

The water-in-oil type aerosol composition thus obtained is filled in a pressure resistant container for an aerosol by a usual method, and an aerosol valve can be attached to obtain an aerosol product.

The pressure resistant container for aerosol is not particularly limited, and a commonly used container can be applied.
When the water-in-oil type aerosol composition is filled in the pressure container for aerosol, the internal pressure of the product is usually 8 k at 35 ° C.
From the viewpoint of safety, it is preferable to adjust to g / cm ² · G or less, especially 7 kg / cm ² · G or less.

In the present invention, as described above, a nonionic surfactant is added to either or both of the oil component and the water component, and the oil component and the water component are mixed. It is possible to produce a water-in-oil type aerosol composition by mixing the stock solution and the liquefied gas, and to fill the composition in the aerosol pressure-resistant container. After separately filling the components with each other to prepare a stock solution, the aerosol pressure-resistant container is filled with a liquefied gas, and the contents are shaken to mix to give a water-in-oil aerosol composition in the aerosol pressure-resistant container. Can also be manufactured.

The form of injection of the water-in-oil type aerosol composition is not particularly limited, and examples thereof include mist form, foam form, stream form, droplet form, paste form and the like.

The production method of the present invention is a method which can easily produce an aerosol composition without requiring complicated steps,
The aerosol composition obtained by the production method is of a water-in-oil type and has excellent storage stability without phase separation.
Further, since it is less irritating to the skin and hair, has excellent affinity, and gives a refreshing feeling without stickiness, it can be suitably used for cosmetics, quasi-drugs, pharmaceuticals and the like.

Next, the water-in-oil type aerosol composition of the present invention and the method for producing the same will be described in more detail based on examples, but the present invention is not limited to these examples.

Example 1 The oil component (A) and the water component (B) shown in Table 1 were separately filled in a pressure container for aerosol (full injection amount: 160 ml) and mixed, and then used as a propellant in Table 1. Gas (C) shown in
Was added, an aerosol valve was attached, and the mixture was mixed with light shaking to obtain an aerosol product filled with the water-in-oil type aerosol composition as a soft pomade.

The internal pressure at this time is 4 kg / 35 ° C.
It was adjusted to be cm ² · G.

[0030]

[Table 1]

The storage stability of the obtained water-in-oil type aerosol composition was measured at room temperature and the state of the composition sprayed immediately after preparation.
The state of the composition sprayed after being left for a month was visually inspected and examined, and evaluated based on the following evaluation criteria. The results are shown in Table 6.

(Evaluation Criteria) A: Even after left standing for 1 month, uniform injection is possible, and there is no change in the state of the injected water-in-oil type aerosol composition. B: Phase separation occurs in the sprayed water-in-oil type aerosol composition after standing for 1 month. C: After being left for 1 month, the sprayed water-in-oil type aerosol composition was completely phase-separated.

Next, 3 g of the water-in-oil type aerosol composition was sprayed onto the hair for hair styling, and the hair styling effect was examined.
It was found that the portion where the water-in-oil type aerosol composition was sprayed had a better hair styling than the portion where it was not sprayed, and the water-in-oil type aerosol composition exhibited a hair styling effect.

As characteristics of the obtained water-in-oil type aerosol composition, about the familiarity to the hair, the feeling of stickiness and the irritation to the skin, the heads (heads) of 50 randomly selected males were immersed in the oil. 3 g of the water-based aerosol composition was jetted and examined, and each was evaluated based on the following evaluation criteria. The results are shown in Table 6.

(Evaluation Criteria) (a) Familiarity with Hair A: 40 or more people felt that they were familiar. B: 30 to 39 people felt familiar. C: 20 to 29 people felt familiar. D: 10 to 19 people felt familiar. E: Only 9 people or less felt familiar.

(B) Sticky feeling A: 9 or less people felt that there was sticky feeling. B: 10 to 19 people felt that it was sticky. C: 20 to 29 people felt that it was sticky. D: 30 to 39 people felt that it was sticky. E: More than 40 people felt sticky.

(C) Skin irritation A: 9 or less people felt irritation on the skin. B: 10 to 19 people felt irritation on the skin. C: 20 to 29 people felt irritation on the skin. D: 30 to 39 people felt irritation on the skin. E: More than 40 people felt irritation on the skin.

Example 2 Oil component (A) and water component (B) used in Example 1
Further, an aerosol product filled with the water-in-oil type aerosol composition as an ultraviolet cut cream was obtained in the same manner as in Example 1 except that the liquefied gas (C) was changed as shown in Table 2.

[0039]

[Table 2]

The storage stability of the obtained water-in-oil type aerosol composition was examined in the same manner as in Example 1. The results are shown in Table 6
Shown in.

Next, 2 g of the water-in-oil type aerosol composition was sprayed on one cheek, and after spending 3 hours outdoors in fine weather, the effect of blocking the ultraviolet rays was examined. The water-in-oil type aerosol composition was sprayed. The cheeks I didn't do became red,
It was found that the sprayed cheek did not change at all, and the water-in-oil type aerosol composition exhibited a UV blocking effect.

Regarding the characteristics of the water-in-oil type aerosol composition, 2 g of the water-in-oil type aerosol composition was applied to the cheeks of 50 randomly selected panelists regarding the familiarity to the skin, the feeling of stickiness and the irritation to the skin. It is sprayed and examined, and each is the same as the evaluation criteria used in Example 1 (however, regarding familiarity with the skin, (a) in Example 1)
Evaluation was made based on the same evaluation standard as that for familiarity with hair). The results are shown in Table 6.

Example 3 Oil component (A) and water component (B) used in Example 1
Further, an aerosol product filled with the water-in-oil type aerosol composition as a skin disease agent (anti-inflammatory agent) was obtained in the same manner as in Example 1 except that the liquefied gas (C) was changed as shown in Table 3.

[0044]

[Table 3]

The storage stability of the obtained water-in-oil type aerosol composition was examined in the same manner as in Example 1. The results are shown in Table 6
Shown in.

Next, 3 g of the water-in-oil type aerosol composition was sprayed onto the inflamed part of the upper arm to examine its anti-inflammatory effect. When the inflammation was subsided, the water-in-oil type aerosol composition exhibited an anti-inflammatory effect. I understood it.

Further, the properties of the water-in-oil type aerosol composition were examined in the same manner as in Example 2 (however, sprayed on the upper arms of 50 randomly selected male and female panelists) and evaluated. The results are shown in Table 6.

Example 4 Oil component (A) and water component (B) used in Example 1
Also, an aerosol product filled with the water-in-oil type aerosol composition as a night cream was obtained in the same manner as in Example 1 except that the liquefied gas (C) was changed as shown in Table 4.

[0049]

[Table 4]

The storage stability of the obtained water-in-oil type aerosol composition was examined in the same manner as in Example 1. The results are shown in Table 6
Shown in.

Next, 2 g of the water-in-oil type aerosol composition was sprayed on one cheek and after going to bed overnight, its moisturizing (moisture-imparting) effect was examined. The water-in-oil type aerosol composition was sprayed. The cheeks were moist and moisturized as compared to the non-sprayed cheeks, and it was found that the water-in-oil type aerosol composition exhibits a moisturizing effect (moisturizing effect).

The characteristics of the water-in-oil type aerosol composition were examined and evaluated in the same manner as in Example 2. The results are shown in Table 6
Shown in.

Example 5 Oil component (A) and water component (B) used in Example 1
Also, an aerosol product filled with the water-in-oil type aerosol composition as an athlete's foot drug was obtained in the same manner as in Example 1 except that the liquefied gas (C) was changed as shown in Table 5.

[0054]

[Table 5]

The storage stability of the obtained water-in-oil type aerosol composition was examined in the same manner as in Example 1. The results are shown in Table 6
Shown in.

Next, 1 g of the water-in-oil type aerosol composition was sprayed onto the athlete's foot part for 2 weeks to examine the healing effect. As a result, athlete's foot was almost healed and the water-in-oil type aerosol composition It was found to exhibit a healing effect on athlete's foot.

Further, the properties of the water-in-oil type aerosol composition were examined in the same manner as in Example 2 (however, sprayed on the toes of 50 randomly selected male panelists) and evaluated. The results are shown in Table 6.

The components shown in Tables 1 to 5 are as shown below.

Liquid paraffin Hicol K-140, diglyceryl monooleate NIKKOL DGMO-C manufactured by Kaneda, decaglyceryl pentaoleate NIKKOL Decaglyn 5-0 manufactured by Nikko Chemicals, diglyceryl manufactured by Nikko Chemicals Dioleate NIKKOL DGMO, manufactured by Nikko Chemicals Co., Ltd. Diglyceryl monostearate NIKKOL DGMS, manufactured by Nikko Chemicals Co., Ltd.

[0060]

[Table 6]

From the results shown in Table 6, the water-in-oil type aerosol compositions obtained in Examples 1 to 5 did not cause phase separation even when stored for a long period of time and had good compatibility. It can be seen that the product is excellent without stickiness and irritation to the skin.

[0062]

The production method of the present invention is a method capable of easily producing an aerosol composition without requiring complicated steps, and the water-in-oil type aerosol composition obtained by the production method does not undergo phase separation. It has excellent storage stability, less irritation to the skin and hair, excellent affinity, and gives a refreshing feeling without stickiness, so it is suitable for use in cosmetics, quasi-drugs, pharmaceuticals, etc. You can

Claims (8)

[Claims] 1. 50 to 97% by weight of a stock solution containing 3 to 50% by weight of an oil component, 0.05 to 10% by weight of a nonionic surfactant and 50 to 95% by weight of a water component, and 3 to 50% by weight of a liquefied gas. % Water-in-oil type aerosol composition. 2. The water-in-oil type aerosol composition according to claim 1, wherein the oil component is at least one selected from hydrocarbons, vegetable oils, animal oils and fatty acid esters. 3. The water-in-oil type aerosol composition according to claim 1, wherein the nonionic surfactant is an ester type nonionic surfactant. 4. The water-in-oil type aerosol composition according to claim 1, 2 or 3, wherein the liquefied gas is liquefied petroleum gas. 5. The water-in-oil type aerosol composition according to claim 1, 2, 3 or 4, wherein the undiluted solution contains a lipophilic powder. 6. A stock solution is prepared by mixing 3 to 50% by weight of an oil component, 0.05 to 10% by weight of a nonionic surfactant and 50 to 95% by weight of a water component with respect to the stock solution, The stock solution 50-97
A method for producing a water-in-oil type aerosol composition, characterized by mixing 3% by weight and 3 to 50% by weight of a liquefied gas. 7. An oil component of 3 to 50% by weight based on the stock solution.
A stock solution was prepared by mixing 50 to 95% by weight of a water component and 0.05 to 10% by weight of a nonionic surfactant.
A method for producing a water-in-oil type aerosol composition, characterized by mixing 3% by weight and 3 to 50% by weight of a liquefied gas. 8. The nonionic surfactant is blended with the oil component so that the total of the amount of the nonionic surfactant mixed with the water component is 0.05 to 10% by weight based on the stock solution. 7
A method for producing the water-in-oil type aerosol composition described.