JPH0676300B2 - Hair cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a hair cosmetic composition, and more particularly to an antidandruff hair cosmetic composition containing mucidin.

[Prior Art] In general, dandruff consists of secretions of sebaceous glands, secretions of sweat glands, and exfoliation of the epidermal layer. Usually, dandruff is caused by increased secretion of skin glands. The outbreak is said to be pathologically facilitated. Therefore, hair cosmetics containing an antibacterial agent have been conventionally used for preventing dandruff.

For example, zinc pyrithione has been conventionally used as the most effective antidandruff drug, but this substance is also well known as being in the category of antibacterial agents.

However, some of these antibacterial agents have safety problems, and it is considered preferable to avoid using them in large amounts as much as possible.

[Problems to be Solved by the Invention] In view of such circumstances, the present inventors obtain an antidandruff substance which is satisfactory from the viewpoint of skin safety and is not inferior to zinc pyrithione in terms of effects. As a result of intensive studies, the inventors have found that the addition of mucidin to hair cosmetics is extremely useful for preventing dandruff and can improve safety, and thus completed the present invention.

[Means for Solving Problems] That is, the present invention is a hair cosmetic composition containing muscidin as an active ingredient.

The structure of muscidin used in the present invention is as shown on the next page.

This muscidin can be obtained by extraction from synthetic or natural products. The method of extracting from a natural product is not particularly limited, but the following method is preferable. Dried Polygonaceae Rumex japonicus Hout
The root part of t) is extracted by heating with dichloromethane, and the crude crystalline substance obtained by distilling dichloromethane off from the extract is recrystallized from petroleum ether to obtain yellow needle crystals. This crystal contains 90% or more of muscidin, and the purity is further improved by repeating recrystallization.

This product may be used in hair cosmetics, but may also be used in the form of an extract solution obtained by the following method.

The dried roots of Rumex japonicus are extracted by heating with hexane, and hexane is completely distilled off from the extract, and then the hexane-soluble part obtained is mixed with various solvents according to the purpose, for example, methanol, ethanol, butanol. Lower alcohols such as
A solution redissolved in an organic solvent such as ether, ethyl acetate, acetone, chloroform, benzene, or a perfume modifier such as triethyl citrate or cosmetic raw materials such as tri (capryl-capric acid) glycerin, squalane, or glyceryl trioctanoate, Used for hair cosmetics. Of course, the hexane solution can be used as it is.

Muscidin thus obtained is 0.00 for hair cosmetics.
The amount is 1 to 1.0% by weight, preferably 0.005 to 0.1% by weight. If it is less than the lower limit, the antidandruff effect tends to be poor, while if it exceeds 1.0% by weight, a large increase in the effect cannot be expected.

In addition to the essential components mentioned above in the hair cosmetic composition of the present invention, components that are usually added, such as oil, ultraviolet absorber, surfactant, preservative, moisturizer, fragrance, hydroalcohol, thickener,
A colorant and the like can be appropriately blended as necessary.

The hair cosmetic composition of the present invention broadly refers to those used for the scalp or hair, and includes, for example, hair tonic hair liquid (liquid hair conditioner), scalp emulsion, hair cream, hair shampoo, hair rinse, hair spray and the like. .

[Effects] The hair cosmetic composition of the present invention is considered to be able to moderately regulate the metabolic reaction in the scalp tissue and significantly prevent the occurrence of dandruff, but its effect is almost equal to or superior to that of zinc pyrithione. It was recognized that

EXAMPLES Next, the present invention will be described in more detail with reference to Examples and Experimental Examples. The present invention is not limited to this. The blending amount is% by weight.

Experimental Example Based on the formulation shown in Table 1, a hair tonic was produced by a conventional method and the antidandruff effect was measured.

(Measurement method for dandruff prevention effect) A test was conducted by selecting 15 men aged 22 to 51 and having a relatively large amount of dandruff.

Before starting the test, wash the hair with a shampoo without addition of chemicals, and make the hair styling with a hair tonic without addition of chemicals.
The accumulated dandruff was collected twice a week for one month, and the amount of protein in the collected dandruff was measured (control period).
Then, the panel was divided into 5 groups of 3 persons each, and the hair tonic containing muscidin and the shampoo containing no drug were used for one month. In the same manner as in the control period, dandruff accumulated twice a week for 2 days after washing hair was collected, and the protein amount was measured (sample period).

Hair tonic is to be used only once a day, and the average dandruff protein amount in the control period and the average dandruff protein amount in the sample period are compared. If the reduction rate of dandruff is 50% or more ... A 40% or more %, Less than 50% …… B 20% or more, less than 40% …… C less than 20% …… D.

The results are shown in Table 1.

As is clear from Table 1, the hair cosmetic composition of the present invention was found to have an excellent antidandruff effect.

Examples of the present invention will be shown below.

Example 1 Polyoxyethylene (8 mol) in 55 g of ethyl alcohol
An appropriate amount of 2 g of oleyl alcohol ether, 0.05 g of muscidin and perfume was added and dissolved at room temperature to obtain an alcohol phase. Separately, 5 g of glycerin was added to 37.95 g of purified water and dissolved by heating. After cooling, an appropriate amount of dye was added, and an alcohol phase was added to the aqueous phase portion to solubilize it to obtain a hair tonic having an antidandruff effect.

Example 2 20 g of polyoxypropylene butyl ether, 2 g of squalane, 0.1 g of mucidin and 52.5 g of ethyl alcohol were dissolved in an alcohol phase at room temperature, and purified water (25.4 g) was added.
Was heated and dissolved, and after cooling, a portion to which an appropriate amount of dye was added was mixed to obtain a hair licked having an antidandruff effect.

Example 3 2 g of stearic acid, 7 g of stearyl alcohol, 2 g of lanolin,
Squalane 5 g, octyldodecanol 6 g, polyoxyethylene (10 mol) cetyl ether 3 g, glyceryl monostearate 2 g, mucidin 0.1 g and flavors were added in appropriate amounts, 80
The oil phase was obtained by heating to ℃. Separately propylene glycol 5
g and 67.9 g of purified water were gradually added to an aqueous phase heated to 80 ° C. with stirring, and the mixture was emulsified and then cooled to obtain a hair cream having an antidandruff effect.

Example 4 2 g of stearic acid, 1.5 g of cetyl alcohol 3 g of petrolatum, 12 g of liquid paraffin, 2 g of polyoxyethylene (10 mol) monooleate, 0.005 g of mucidin and an appropriate amount of perfume were mixed and heated to 80 ° C. to obtain an oil phase. It was Separately, propylene glycol 5g, triethanolamine 1g and purified water 73.495g
Was heated to 80 ° C., the above oil phase was gradually added to this aqueous phase with stirring, and after emulsification, it was cooled to obtain a scalp emulsion having an antidandruff effect.

Example 5 To 79.95 g of purified water, triethanolamine 15 of lauryl sulfate was added.
g, coconut oil fatty acid monoethanol amide 5g, muscidin
0.05 g, an appropriate amount of coloring matter and fragrance were added, and the mixture was heated and mixed, and then cooled to obtain a hair shampoo having an antidandruff effect.

Example 6 3.5 g of polyethylene glycol 1500 and 1 g of triethanolamine were dissolved by heating in 74.49 g of purified water and kept at 70 ° C. Stearic acid 2.5 g, cetyl alcohol 1.5 g, petrolatum 5 g, squalane 10 g, polyoxyethylene (10 mol) monooleate 2 g, and mucidin 0.01 g are dissolved by heating to 70
It was kept at ℃ and added to the water phase part. After pre-emulsification, it was uniformly emulsified with a honomixer and gradually cooled to obtain a hair emulsion having an antidandruff effect.

Claims (1)

[Claims] 1. A hair cosmetic composition comprising muscidin.