JPH0698903A - Production of bioimplant material - Google Patents

Production of bioimplant material

Info

Publication number
JPH0698903A
JPH0698903A JP27651592A JP27651592A JPH0698903A JP H0698903 A JPH0698903 A JP H0698903A JP 27651592 A JP27651592 A JP 27651592A JP 27651592 A JP27651592 A JP 27651592A JP H0698903 A JPH0698903 A JP H0698903A
Authority
JP
Japan
Prior art keywords
bioimplant material
bioimplant
element body
ion implantation
nitrogen ion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP27651592A
Other languages
Japanese (ja)
Inventor
Motoi Sakai
基 酒井
Shinichi Miyamoto
伸一 宮本
Tateaki Sahira
健彰 佐平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Materials Corp
Original Assignee
Mitsubishi Materials Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Materials Corp filed Critical Mitsubishi Materials Corp
Priority to JP27651592A priority Critical patent/JPH0698903A/en
Publication of JPH0698903A publication Critical patent/JPH0698903A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof

Landscapes

  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

(57)【要約】 【目的】 摺動面の摩耗を抑制して、摩耗粉の生体内へ
の放出を防止し得る生体インプラント材を製造する。 【構成】 ステップ１で精密鋳造した生体インプラント
材の素体に、ステップ２で熱間静水圧プレスを施した
後、ステップ３でその表面を球状に切削する。次いで、
ステップ４で素体の表面を鏡面研磨した後、ステップ５
で素体表面に窒素イオン注入処理を施すことにより、生
体インプラント材を得る。 (57) [Abstract] [Purpose] To produce a bioimplant material that can suppress wear of a sliding surface and prevent wear powder from being released into the body. [Structure] The body of the bioimplant material precision-cast in step 1 is subjected to hot isostatic pressing in step 2, and then the surface is cut into a spherical shape in step 3. Then
After mirror polishing the surface of the element body in step 4, step 5
By subjecting the surface of the element body to nitrogen ion implantation, a biological implant material is obtained.

Description

【発明の詳細な説明】Detailed Description of the Invention

【０００１】[0001]

【産業上の利用分野】この発明は医療分野において用い
られる例えば人工関節骨頭ボールやアウターヘッド等の
所謂生体インプラント材の製造方法に関するものであ
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for producing a so-called bioimplant material such as an artificial joint head ball or outer head used in the medical field.

【０００２】[0002]

【従来の技術】従来、図２に示す如く生体インプラント
材の１つとして、チタン合金製ステム１の先端部にチタ
ン合金製骨頭ボール２を固着し、該骨頭ボール２を高密
度ポリエチレン製受け部材３に摺動自在に係合して成る
人工股関節が知られている。このような人工股関節にお
ける骨頭ボール２は従来、次のようにして製造してい
た。即ち、まず、精密鋳造法（例えばロストワックス
法）を用いて、その鋳型にチタン合金を鋳込んで球状の
骨頭ボール素体を鋳造する。次に、この素体の表面を旋
盤によりＲmax ：１〜２μｍ程度まで球面に切削加工し
た後、この素体の表面を研磨処理してＲmax ：０．４〜
０．５μｍ程度まで鏡面状に仕上げることにより、骨頭
ボール２を得るものである。2. Description of the Related Art Conventionally, as shown in FIG. 2, as one of bioimplant materials, a titanium alloy femoral head ball 2 is fixed to a distal end of a titanium alloy stem 1, and the femoral head ball 2 is made of a high density polyethylene receiving member. There is known an artificial hip joint which is slidably engaged with the joint 3. Conventionally, the bone head ball 2 in such an artificial hip joint is manufactured as follows. That is, first, a precision casting method (for example, the lost wax method) is used to cast a titanium alloy into the mold to cast a spherical head bone element. Next, the surface of this element body is cut by a lathe to a spherical surface up to about Rmax: 1 to 2 μm, and then the surface of this element body is polished to obtain Rmax: 0.4-
The bone head ball 2 is obtained by finishing the surface to a mirror surface of about 0.5 μm.

【０００３】[0003]

【発明が解決しようとする課題】斯かる従来の骨頭ボー
ル２などの生体インプラント材においては、鋳造に起因
する微小な引け巣（鋳型に注入した溶湯が凝固する際、
先に凝固収縮した部分に引っ張られて、ロート状に陥入
した部分）、或は鏡面研磨処理時におけるチタン合金中
の析出物等に起因して、鏡面研磨処理後の表面に微小欠
陥及び荒れが発生する。このため上述した従来の人工股
関節においては、骨頭ボール２と受け部材３の互いの摺
動面が摩耗し、その摩耗粉（チタン合金及び高密度ポリ
エチレン）が生体内に放出され、発癌、アレルギー等の
生体反応を起こす虞があるという問題点があった。In the conventional bioimplant material such as the bone head ball 2 as described above, a minute shrinkage cavity caused by casting (when the molten metal injected into the mold is solidified,
Microdefects and roughness on the surface after the mirror polishing process due to the part that was pulled into the part that had solidified and contracted first and then entered into the funnel shape), or the precipitate in the titanium alloy during the mirror polishing process. Occurs. For this reason, in the above-mentioned conventional artificial hip joint, the sliding surfaces of the femoral head ball 2 and the receiving member 3 are worn, and the abrasion powder (titanium alloy and high-density polyethylene) is released into the living body, causing carcinogenesis, allergies, etc. However, there is a problem that the biological reaction of

【０００４】[0004]

【課題を解決するための手段】そこで、本発明者等は、
上述のような観点から、摺動面の摩耗を抑制して、摩耗
粉の生体内への放出を防止し得る生体インプラント材を
製造すべく研究を行なった結果、精密鋳造法によりチタ
ン又はチタン合金製の生体インプラント材の素体を鋳造
し、該素体に熱間静水圧プレスを施した後、前記素体に
切削加工を施し、引続いてその表面を研磨処理して鏡面
状に仕上げ、その後前記素体に窒素イオン注入処理を施
すと、この結果製造されたインプラント材は、精密鋳造
した素体への熱間静水圧プレスにより、該素体の引け巣
が除去され、また、素体の表面を鏡面研磨した後に施さ
れた窒素イオン注入処理により表面粗度は、微小欠陥及
び荒れのない小さなものとなるという研究結果を得たの
である。Therefore, the present inventors have
From the above viewpoints, as a result of research to manufacture a bioimplant material that can suppress wear of sliding surfaces and prevent wear powder from being released into the living body, titanium or titanium alloy is produced by precision casting. Cast body of bioimplant material made of, after subjected to hot isostatic pressing to the body, subjecting the body to a cutting process, subsequently polishing the surface to a mirror finish, After that, when the element body is subjected to nitrogen ion implantation treatment, the implant material produced as a result is that the shrinkage cavities of the element body are removed by hot isostatic pressing of the precision cast element body. We obtained the research result that the surface roughness becomes small without micro-defects and roughness by the nitrogen ion implantation treatment performed after the surface of the is polished.

【０００５】[0005]

【実施例】この発明は、上記の研究結果にもとづいてな
されたものであって、以下にこの発明の方法を実施例に
より具体的に説明する。図１はこの発明の生体インプラ
ント材の製造方法を示すフローチャートである。まず、
ロストワックス法等によりチタン合金（Ｔｉ−６重量％
Ａｌ−４重量％Ｖ，ＥＬＩ）製の球状（直径：２２mm）
素体を精密鋳造する（ステップ１）。次に、この素体
に、Ａｒ（アルゴンガス）雰囲気中、温度：９００℃、
圧力：１０００気圧、時間：２時間の条件で、熱間静水
圧プレスを施して、引け巣等の微小な鋳造欠陥を除去す
る（ステップ２）。この後、素体の表面を旋盤により球
状に切削加工して（ステップ３）、更にその素体の表面
を鏡面状に研磨処理する（ステップ４）。次に、この素
体の表面に高真空中で１０時間、窒素イオン注入処理
（注入量は４×１０17個／cm2 ）を行なう（ステップ
５）。以上のステップ１〜ステップ５により、人工股関
節のうちの骨頭ボールを製造した。The present invention has been made based on the above-mentioned research results, and the method of the present invention will be specifically described below with reference to Examples. FIG. 1 is a flow chart showing a method for producing a bioimplant material of the present invention. First,
Titanium alloy (Ti-6% by weight)
Al-4 wt% V, ELI) spherical (diameter: 22 mm)
Precision casting of an element body (step 1). Next, this element was placed in an Ar (argon gas) atmosphere at a temperature of 900 ° C.
Hot isostatic pressing is performed under the conditions of pressure: 1000 atm and time: 2 hours to remove minute casting defects such as shrinkage cavities (step 2). Then, the surface of the element body is cut into a spherical shape by a lathe (step 3), and the surface of the element body is further polished to be a mirror surface (step 4). Next, the surface of this element body is subjected to nitrogen ion implantation treatment (implantation amount is 4 × 10 17 / cm 2 ) in a high vacuum for 10 hours (step 5). Through the above steps 1 to 5, the head ball of the artificial hip joint was manufactured.

【０００６】上述した本発明方法により得られた骨頭ボ
ールの表面状態を光学顕微鏡で観察した結果、引け巣等
の微小な鋳造欠陥は発見されなかった。また、この骨頭
ボールの表面粗度を非接触表面形状測定器により測定し
たところ、従来（熱間静水圧プレス及び窒素イオン注入
処理を行なわない以外は同一の条件で実施）により得ら
れた骨頭ボールの表面粗度に比して、本発明方法により
得られた骨頭ボールの表面粗度が大幅に小さいことを確
認できた。上述した本発明方法及び、従来方法並びに比
較方法１〜３により、それぞれ得られた骨頭ボールの表
面状態（引け巣等の微小な鋳造欠陥の有無）及び表面最
大粗度（ｎｍ）の比較結果を表１に示す。As a result of observing the surface condition of the head ball obtained by the above-mentioned method of the present invention with an optical microscope, no minute casting defects such as shrinkage cavities were found. Also, the surface roughness of this head ball was measured by a non-contact profilometer, and it was obtained by the conventional method (performed under the same conditions except that hot isostatic pressing and nitrogen ion implantation were not performed). It was confirmed that the surface roughness of the head ball obtained by the method of the present invention was significantly smaller than the surface roughness of the above. The results of comparison of the surface condition (presence or absence of minute casting defects such as shrinkage cavities) and the maximum surface roughness (nm) of the bone head balls obtained by the above-described method of the present invention, the conventional method, and the comparison methods 1 to 3 are shown. It shows in Table 1.

【０００７】[0007]

【表１】 [Table 1]

【０００８】[0008]

【発明の効果】この表１から、熱間静水圧プレスを施す
ことにより、引け巣等の微小な鋳造欠陥が無くなり、ま
た窒素イオン注入処理を施すことにより表面粗度が小さ
くなり、さらに特に窒素イオン注入量を４×１０17個／
cm2 以上にすれば表面粗度がより一層小さくなることが
明らかである。なお、上記実施例では、人工股関節にお
ける骨頭ボールについて述べたが、アウターヘッド等の
この種の生体インプラント材に対して幅広く適用し得る
ものであり、その他の点に関しても本発明の要旨を逸脱
しない範囲で種々変更し得ることは言うまでもない。以
上の如くこの発明の方法によれば、表面に引け巣等の微
小な鋳造欠陥が無く、その表面粗度が小さな生体インプ
ラント材を製造することができる。また、この発明の方
法により得られた生体インプラント材によれば、摺動面
の摩耗が抑制され、摩耗粉の生体内への放出が防止され
るのである。According to Table 1, hot isostatic pressing eliminates minute casting defects such as shrinkage cavities, and nitrogen ion implantation reduces surface roughness. Ion implantation amount is 4 × 10 17 /
It is clear that the surface roughness becomes even smaller when the area is cm 2 or more. In addition, although the femoral head ball in the artificial hip joint is described in the above embodiment, it can be widely applied to this type of bioimplant material such as the outer head, and other points do not depart from the gist of the present invention. It goes without saying that various changes can be made within the range. As described above, according to the method of the present invention, it is possible to manufacture a bioimplant material having no small casting defects such as shrinkage cavities on the surface and having a small surface roughness. Further, according to the biological implant material obtained by the method of the present invention, abrasion of the sliding surface is suppressed, and release of abrasion powder into the living body is prevented.

【図面の簡単な説明】[Brief description of drawings]

【図１】この発明の方法を示すフローチャートである。FIG. 1 is a flow chart showing the method of the present invention.

【図２】人工股関節の斜視図である。FIG. 2 is a perspective view of an artificial hip joint.

【符号の説明】[Explanation of symbols]

１ ステム ２ 骨頭ボール ３ 受け部材 1 Stem 2 Bone head ball 3 Receiving member

Claims (2)

【特許請求の範囲】[Claims] 【請求項１】 精密鋳造法によりチタン又はチタン合金
製の生体インプラント材の素体を鋳造し、該素体に熱間
静水圧プレスを施した後、前記素体に切削加工を施し、
引続いてその表面を研磨処理して鏡面状に仕上げ、その
後前記素体に窒素イオン注入処理を施すことを特徴とす
る生体インプラント材の製造方法。1. A body of a bioimplant material made of titanium or a titanium alloy is cast by a precision casting method, hot isostatic pressing is performed on the body, and then the body is cut.
A method for producing a bioimplant material, characterized in that the surface thereof is subsequently polished to be mirror-finished, and then the element body is subjected to nitrogen ion implantation treatment. 【請求項２】 前記窒素イオン注入処理による窒素イオ
ンの注入量が４×１０17個／cm2 以上であることを特徴
とする請求項１記載の生体インプラント材の製造方法。2. The method for producing a bioimplant material according to claim 1, wherein the implantation amount of nitrogen ions by the nitrogen ion implantation treatment is 4 × 10 17 ions / cm 2 or more.
JP27651592A 1992-09-21 1992-09-21 Production of bioimplant material Withdrawn JPH0698903A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP27651592A JPH0698903A (en) 1992-09-21 1992-09-21 Production of bioimplant material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27651592A JPH0698903A (en) 1992-09-21 1992-09-21 Production of bioimplant material

Publications (1)

Publication Number Publication Date
JPH0698903A true JPH0698903A (en) 1994-04-12

Family

ID=17570550

Family Applications (1)

Application Number Title Priority Date Filing Date
JP27651592A Withdrawn JPH0698903A (en) 1992-09-21 1992-09-21 Production of bioimplant material

Country Status (1)

Country Link
JP (1) JPH0698903A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004071350A1 (en) * 2003-02-12 2004-08-26 Australian Surgical Design And Manufacture Pty Limited Surface preparation of an implant
EP1905461A1 (en) * 2006-09-28 2008-04-02 Ethicon Endo-Surgery, Inc. Cast parts with improved surface properties and methods for their production
JP4796737B2 (en) * 2000-07-10 2011-10-19 エクソジェネシス コーポレーション Improvement of artificial hip joint by GCIB

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4796737B2 (en) * 2000-07-10 2011-10-19 エクソジェネシス コーポレーション Improvement of artificial hip joint by GCIB
WO2004071350A1 (en) * 2003-02-12 2004-08-26 Australian Surgical Design And Manufacture Pty Limited Surface preparation of an implant
GB2412338A (en) * 2003-02-12 2005-09-28 Australian Surgical Design And Surface preparation of an implant
GB2412338B (en) * 2003-02-12 2007-01-10 Australian Surgical Design & M Surface preparation of an implant
AU2004212213B2 (en) * 2003-02-12 2009-10-08 Advanced Surgical Design & Manufacture Limited Surface preparation of an implant
US8163111B2 (en) 2003-02-12 2012-04-24 Advanced Surgical Design & Manufacture Limited Surface preparation of an implant
EP1905461A1 (en) * 2006-09-28 2008-04-02 Ethicon Endo-Surgery, Inc. Cast parts with improved surface properties and methods for their production
JP2008080403A (en) * 2006-09-28 2008-04-10 Ethicon Endo Surgery Inc Cast parts with improved surface properties and methods for their production
US7762308B2 (en) 2006-09-28 2010-07-27 Ethicon Endo-Surgery, Inc. Cast parts with improved surface properties and methods for their production

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Effective date: 19991130