JPH07116150B2 - 安息香酸誘導体 - Google Patents

安息香酸誘導体

Info

Publication number
JPH07116150B2
JPH07116150B2 JP3511468A JP51146891A JPH07116150B2 JP H07116150 B2 JPH07116150 B2 JP H07116150B2 JP 3511468 A JP3511468 A JP 3511468A JP 51146891 A JP51146891 A JP 51146891A JP H07116150 B2 JPH07116150 B2 JP H07116150B2
Authority
JP
Japan
Prior art keywords
pyridyl
aliphatic group
compound according
ethyl
methoxyphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3511468A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05507492A (ja
Inventor
デイニーズ，ロバート・エイ
キングスベリー，ウイリアム・デニス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH05507492A publication Critical patent/JPH05507492A/ja
Publication of JPH07116150B2 publication Critical patent/JPH07116150B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP3511468A 1990-06-07 1991-05-31 安息香酸誘導体 Expired - Lifetime JPH07116150B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53439790A 1990-06-07 1990-06-07
US534,397 1990-06-07
PCT/US1991/003772 WO1991018601A1 (en) 1990-06-07 1991-05-31 Benzoic acid derivatives

Publications (2)

Publication Number Publication Date
JPH05507492A JPH05507492A (ja) 1993-10-28
JPH07116150B2 true JPH07116150B2 (ja) 1995-12-13

Family

ID=24129867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3511468A Expired - Lifetime JPH07116150B2 (ja) 1990-06-07 1991-05-31 安息香酸誘導体

Country Status (17)

Country Link
EP (1) EP0593464A1 (2)
JP (1) JPH07116150B2 (2)
KR (1) KR930700102A (2)
CN (1) CN1058015A (2)
AU (1) AU655428B2 (2)
CA (1) CA2083957A1 (2)
FI (1) FI925545A0 (2)
HU (1) HUT64747A (2)
IL (1) IL98387A0 (2)
MA (1) MA22195A1 (2)
MX (1) MX26167A (2)
NZ (1) NZ238426A (2)
PL (1) PL290587A1 (2)
PT (1) PT97913A (2)
TW (1) TW221809B (2)
WO (1) WO1991018601A1 (2)
ZA (1) ZA914322B (2)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06510786A (ja) * 1991-09-19 1994-12-01 スミスクライン・ビーチャム・コーポレイション ロイコトリエン関連疾患治療用ピリジン化合物
EP0649408A4 (en) * 1992-06-30 1995-06-21 Smithkline Beecham Corp METHOD FOR THE PRODUCTION OF PHENYLTHIOMETHYLPYRIDINYLALKENOATS.
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
DE4224402A1 (de) * 1992-07-21 1994-01-27 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
GR1001409B (el) * 1992-10-15 1993-11-30 Smithkline Beecham Corp Ενώσεις για την ?εραπευτική αγωγή ασ?ενειών που έχουν σχέση με λευκοτριένια.
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
US5643914A (en) * 1993-03-02 1997-07-01 Smithkline Beecham Corporation Pharmaceutical pyridine compounds
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
EP0942903A1 (en) 1996-09-26 1999-09-22 Novartis AG Aryl-substituted acrylamides with leukotriene b4 (ltb-4) receptor antagonist activity
US7850970B2 (en) 2003-08-26 2010-12-14 The Regents Of The University Of Colorado Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
WO2019244464A1 (ja) * 2018-06-22 2019-12-26 パナソニック株式会社 有機塩とこれを備えるヒドロキシラジカルセンサ及び検出メディア

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056619A (en) * 1975-09-08 1977-11-01 Warner-Lambert Company 1-Substituted-2-(2-pyridinyl)ethanone N-oxides

Also Published As

Publication number Publication date
TW221809B (2) 1994-03-21
EP0593464A1 (en) 1994-04-27
EP0593464A4 (en) 1993-02-12
HU9203867D0 (en) 1993-03-29
KR930700102A (ko) 1993-03-13
JPH05507492A (ja) 1993-10-28
MA22195A1 (fr) 1992-04-01
FI925545L (fi) 1992-12-07
IL98387A0 (en) 1992-07-15
WO1991018601A1 (en) 1991-12-12
AU655428B2 (en) 1994-12-22
ZA914322B (en) 1992-06-24
MX26167A (es) 1994-02-28
CA2083957A1 (en) 1991-12-08
FI925545A7 (fi) 1992-12-07
HUT64747A (en) 1994-02-28
AU8189691A (en) 1991-12-31
CN1058015A (zh) 1992-01-22
NZ238426A (en) 1994-11-25
PT97913A (pt) 1992-03-31
FI925545A0 (fi) 1992-12-07
PL290587A1 (en) 1992-08-24

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