JPH07242530A - Skin cosmetic - Google Patents

Abstract

PURPOSE:To obtain a skin cosmetic exhibiting remarkable chapped skin improving effect and giving excellent feeling to the skin. CONSTITUTION:This skin cosmetic contains (A) diisopropylamine dichloroacetate and/or gamma-aminobutyric acid and (B) at least one kind of compound selected from a 3-18C alpha-hydroxycarboxylic acid such as lactic acid and its salt, alpha- hydroxyoctanoic acid and alpha-hydroxymyristic acid in amounts of 0.001-3.0wt.% of the component A and 0.001-25wt.% of the component B. The skin cosmetic can be prepared in the form of lotion, milky lotion, cream, pack, etc., by conventional method.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a skin cosmetic having a rough skin improving effect and an excellent feeling in use.

[0002]

2. Description of the Related Art Conventionally, skin cosmetics having a rough skin improving effect have been developed (for example, Japanese Patent Publication No. 5-1763). However, the effect is not sufficient, and further development is desired.

On the other hand, in the case of incorporating diisopropylamine dichloroacetate and γ-aminobutyric acid, which are known to exist in living tissues, in order to maintain healthy skin, the moisturizing function of the skin is enhanced. It is known (Japanese Patent Publication No. 4-65047, JP-A-62-1).
48414), the effect was not sufficient, and the feeling of use was not sufficiently satisfied.

In view of such a situation, the inventors of the present invention have made earnest studies to improve the difficulties of the prior art, and as a result,
Diisopropylamine dichloroacetate (hereinafter DAD
Abbreviated as A) and / or γ-aminobutyric acid, and at least one kind of α-hydroxycarboxylic acid having 3 to 18 carbon atoms, the skin cosmetic composition is rough due to a synergistic effect. The present invention has been completed by discovering that rough skin is improved by further densifying and promoting the structure of the skin, and that it is also excellent in the feeling of use.

It is an object of the present invention to provide a skin cosmetic having an effect of improving rough skin and an excellent feeling in use.

[0006]

The above objects are characterized by containing diisopropylamine dichloroacetate and / or γ-aminobutyric acid and at least one α-hydroxycarboxylic acid having 3 to 18 carbon atoms. It is achieved by skin cosmetics.

The α-hydroxycarboxylic acid having 3 to 18 carbon atoms used in the skin cosmetic of the present invention is a known substance and is easily available. For example, lactic acid and its salts, α-hydroxyoctanoic acid, α-hydroxymyristic acid are applied.

DADA used in the skin cosmetic of the present invention
Is a known substance and is easily available. Sudden·
Chronic hepatitis, liver disorders such as fatty liver and cerebral hemorrhage, cerebral thrombosis,
It is applied as a therapeutic agent for hypertension.

The .gamma.-aminobutyric acid used in the skin cosmetic of the present invention is a known substance and is easily available. It exists widely in the plant kingdom in a free form, and it is abundant in the brain in animals, plays an important role in brain metabolism, and is used for improving the aftereffects of cerebrovascular disorders and improving muscle atrophy. Also,
As the action of the nuclear substance on the skin, it is said that it has an action of enhancing the skin action by a skin peripheral vasodilatory action, healing fatigue and sagging of the skin, and preventing aging and wrinkles.

The blending amount of α-hydroxycarboxylic acid in the skin cosmetic of the present invention is preferably 0.001 to 25% by weight (hereinafter referred to as wt%) based on the total amount.

If the blending amount is less than 0.001 wt%, the effect of the present invention is not so sufficient. On the other hand, if the blending amount exceeds 25 wt%,
It cannot be hoped that the effects will be correspondingly increased.

The amount of DADA and γ-aminobutyric acid to be incorporated into the skin cosmetic of the present invention is a dry solid amount, and is preferably 0.001 to 3.0 wt% based on the total amount.

If the blending amount of these is less than 0.001 wt%, the effect aimed at by the present invention is not so sufficient. On the other hand, even if the blending amount of each exceeds 3.0 wt%, the increase amount is increased. It is not possible to expect significant improvement in the effect.

The skin cosmetic of the present invention can be formulated into lotions, emulsions, creams, packs and the like according to a conventional method.

It is to be noted that the skin cosmetic of the present invention can be appropriately blended with a dye, a fragrance, an antiseptic, a surfactant, a pigment and the like within the range where the object of the present invention is achieved.

[0016]

EXAMPLES The present invention will be described in detail below based on examples and comparative examples.

(1) Practical test for rough skin described in Examples,
(2) Sensory test Each test method is as follows.

(1) Practical test for rough skin Female subjects (25 to 50 years old) who complain of rough skin, dry skin, etc.
A sample and a base were applied to the affected area half of each of 20 people twice a day for 3 consecutive months. The evaluation is shown by the number of people who answered that the skin was moisturized at the sample application part.

(2) Sensory test (feeling of use) 20 subjects evaluated the characteristics of the sample after continuously using the sample for 10 days. The evaluation was shown by the number of respondents who answered that "the skin was moisturized" and "the skin had a good affinity" with respect to the questionnaire items concerning the wettability and the affinity.

Examples 1 to 5 and Comparative Examples 1 to 5 In the raw material compositions shown in Table 1, active ingredients were blended as shown in Table 2 to prepare lotions as described below, and the above-mentioned various tests were carried out.

[0021]

[Table 1]

[0022]

[Table 2]

(1) Preparation method Component B shown in Table 1 is uniformly dissolved in component A, and component C is uniformly dissolved in component D, then component A and component D are uniformly mixed and dispersed by stirring, and then filled in a container. To do. At the time of use, the contents should be evenly dispersed by shaking. (2) Characteristics Table 2 shows the results of various tests.

As shown in Table 2, Comparative Example 1 did not show good results in various tests. On the other hand, the skin cosmetics of the present invention of Examples 1 to 5 showed clearly good results in all the tests.

Examples 6 to 9 and Comparative Examples 6 to 9 In the raw material compositions shown in Table 3, active ingredients were blended as shown in Table 4 to prepare skin creams, and the above-mentioned tests were carried out.

[0026]

[Table 3]

[0027]

[Table 4]

(1) Preparation method The F component shown in Table 3 is mixed with the E component, and the E component and the H component are uniformly heated and dissolved to bring the temperature to 80 ° C. Next, the H component is poured into the E component and mixed by stirring, then cooled with stirring, and the G component is charged at about 50 ° C. and cooled to 30 ° C.

(2) Characteristics The results of various tests are shown in Table 4. As shown in Table 4, Examples 6 to 9 clearly showed good results in all the tests. In contrast, Comparative Examples 6 to 9 were significantly inferior.

[0030]

Industrial Applicability As described above, it is apparent that the present invention provides a useful skin cosmetic having a remarkable rough skin improving effect and an excellent feeling in use.

Claims (1)

[Claims] 1. A skin cosmetic composition comprising diisopropylamine dichloroacetate and / or γ-aminobutyric acid and at least one α-hydroxycarboxylic acid having 3 to 18 carbon atoms.