JPH0725719A - Extract antimicrobial agent from resin of araucaria angustifolia - Google Patents
Extract antimicrobial agent from resin of araucaria angustifoliaInfo
- Publication number
- JPH0725719A JPH0725719A JP19687793A JP19687793A JPH0725719A JP H0725719 A JPH0725719 A JP H0725719A JP 19687793 A JP19687793 A JP 19687793A JP 19687793 A JP19687793 A JP 19687793A JP H0725719 A JPH0725719 A JP H0725719A
- Authority
- JP
- Japan
- Prior art keywords
- resin
- antimicrobial agent
- knoblike
- mass
- penicillium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 240000000940 Araucaria angustifolia Species 0.000 title claims abstract description 19
- 235000018719 Araucaria angustifolia Nutrition 0.000 title claims abstract description 19
- 239000011347 resin Substances 0.000 title claims abstract description 19
- 229920005989 resin Polymers 0.000 title claims abstract description 19
- 239000000284 extract Substances 0.000 title claims abstract description 4
- 239000004599 antimicrobial Substances 0.000 title abstract 6
- 239000003242 anti bacterial agent Substances 0.000 claims description 4
- 210000001099 axilla Anatomy 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 8
- 239000000126 substance Substances 0.000 abstract description 8
- 239000002904 solvent Substances 0.000 abstract description 6
- 235000019441 ethanol Nutrition 0.000 abstract description 4
- 241000228245 Aspergillus niger Species 0.000 abstract description 3
- 241000228254 Aspergillus restrictus Species 0.000 abstract description 3
- 241001465318 Aspergillus terreus Species 0.000 abstract description 3
- 241000228143 Penicillium Species 0.000 abstract description 3
- 241000223678 Aureobasidium pullulans Species 0.000 abstract description 2
- 241001515917 Chaetomium globosum Species 0.000 abstract description 2
- 241000603729 Geotrichum sp. Species 0.000 abstract description 2
- 241000228153 Penicillium citrinum Species 0.000 abstract description 2
- 241001136494 Talaromyces funiculosus Species 0.000 abstract description 2
- 230000000845 anti-microbial effect Effects 0.000 abstract 2
- 241001482888 Aspergillus tonophilus Species 0.000 abstract 1
- 241001149955 Cladosporium cladosporioides Species 0.000 abstract 1
- 241001207508 Cladosporium sp. Species 0.000 abstract 1
- 241000233732 Fusarium verticillioides Species 0.000 abstract 1
- 241000235546 Rhizopus stolonifer Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 description 8
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 description 4
- 239000002689 soil Substances 0.000 description 4
- HGXBRUKMWQGOIE-AFHBHXEDSA-N (+)-pinoresinol Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@@H]3[C@@H]([C@H](OC3)C=3C=C(OC)C(O)=CC=3)CO2)=C1 HGXBRUKMWQGOIE-AFHBHXEDSA-N 0.000 description 3
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 3
- 235000007221 pinoresinol Nutrition 0.000 description 3
- OHOPKHNWLCMLSW-UHFFFAOYSA-N pinoresinol Natural products C1=C(O)C(OC)=CC(C2C3C(C(OC3)C=3C=C(CO)C(O)=CC=3)CO2)=C1 OHOPKHNWLCMLSW-UHFFFAOYSA-N 0.000 description 3
- BURBOJZOZGMMQF-UHFFFAOYSA-N xanthoxylol Natural products C1=C(O)C(OC)=CC=C1C1C(COC2C=3C=C4OCOC4=CC=3)C2CO1 BURBOJZOZGMMQF-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 229930007845 β-thujaplicin Natural products 0.000 description 2
- MHXCIKYXNYCMHY-AUSJPIAWSA-N (+)-lariciresinol Chemical compound C1=C(O)C(OC)=CC(C[C@@H]2[C@@H]([C@H](OC2)C=2C=C(OC)C(O)=CC=2)CO)=C1 MHXCIKYXNYCMHY-AUSJPIAWSA-N 0.000 description 1
- PUETUDUXMCLALY-HOTGVXAUSA-N (-)-secoisolariciresinol Chemical compound C1=C(O)C(OC)=CC(C[C@@H](CO)[C@H](CO)CC=2C=C(OC)C(O)=CC=2)=C1 PUETUDUXMCLALY-HOTGVXAUSA-N 0.000 description 1
- VEAUNWQYYMXIRB-ZZXKWVIFSA-N 4-[(1e)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol Chemical compound C1=CC(O)=CC=C1\C=C\C(C=C)C1=CC=C(O)C=C1 VEAUNWQYYMXIRB-ZZXKWVIFSA-N 0.000 description 1
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000222290 Cladosporium Species 0.000 description 1
- 241001558166 Curvularia sp. Species 0.000 description 1
- 241001136487 Eurotium Species 0.000 description 1
- 241000223218 Fusarium Species 0.000 description 1
- YVRYZXAHRGGELT-UHFFFAOYSA-N Lariciresinol Natural products C1=C2OCOC2=CC(C2C(C)C3(OC)C=C(CC=C)C(=O)CC3(O2)OC)=C1 YVRYZXAHRGGELT-UHFFFAOYSA-N 0.000 description 1
- 241000700601 Moniliformis Species 0.000 description 1
- VEAUNWQYYMXIRB-UHFFFAOYSA-N Nyasol Natural products C1=CC(O)=CC=C1C=CC(C=C)C1=CC=C(O)C=C1 VEAUNWQYYMXIRB-UHFFFAOYSA-N 0.000 description 1
- 241001236817 Paecilomyces <Clavicipitaceae> Species 0.000 description 1
- 235000002233 Penicillium roqueforti Nutrition 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 241000235527 Rhizopus Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000003849 aromatic solvent Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 235000006826 lariciresinol Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- OGFXBIXJCWAUCH-UHFFFAOYSA-N meso-secoisolariciresinol Natural products C1=2C=C(O)C(OC)=CC=2CC(CO)C(CO)C1C1=CC=C(O)C(OC)=C1 OGFXBIXJCWAUCH-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 235000004239 secoisolariciresinol Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- 238000004078 waterproofing Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
【0001】[0001]
【産業上の利用分野】この発明は、パラナ松樹脂からの
抽出物抗菌剤に関するものである。FIELD OF THE INVENTION The present invention relates to an antibacterial agent for extracts from Parana pine resin.
【0002】[0002]
【技術的背景】南米ブラジル国の南部を中心とする地域
に自生する松の一種で、パラナ松(学名Araucar
ia angustifolia)と称される。[Technical background] South America A kind of pine that grows naturally in the southern part of Brazil. Parana pine (scientific name Araucar
ia angustifolia).
【0003】パラナ松は、幹から支成する枝の育成分岐
部に掌の拳大よりラグビーボール大程度のレジンを多く
含有するコブ状の塊を生成することが特徴である。Parana pine is characterized in that it produces a lump-shaped mass containing a large amount of resin, which is about the size of a rugby ball rather than the size of a fist of the palm, at the nurturing branch of the branch borne by the trunk.
【0004】[0004]
【従来の技術】前記したパラナ松(学名Araucar
ia Angustifolia)のコブ状塊(以下コ
ブ状塊と称す)は、これに含まれるレジンを抽出して、
木工用ならびに靴用のワニス、パラフィンと混合して紙
の防水加工用剤、フェノール樹脂を配合して固形樹脂製
品および塗料原料等、一般工業製品あるいはその原料の
添加剤として用いられている。2. Description of the Related Art Parana pine (scientific name Araucar
ia Angustifolia) lumps (hereinafter referred to as lumps) are extracted from the resin contained therein,
It is used as a varnish for woodworking and shoes, a waterproofing agent for paper mixed with paraffin, and a phenol resin mixed with it as a general industrial product such as a solid resin product and a paint raw material, or an additive for the raw material.
【0005】[0005]
【発明が解決しようとする課題】このパラナ松のコブ状
塊は、現在は、土中より掘り出し収穫している。The lump-shaped lump of Parana pine is currently dug and harvested from the soil.
【0006】この埋在形態を分析するに、コブ状塊をつ
けたまま枝が落ち、長期を経て土中に没し、枝の部分は
朽ち果てて土に変化した後でも前記のコブ状塊は数10
0年を経ても変化せずに残存し、現在生成されている形
態をそのままの姿で産出されている現状から、これらコ
ブ状塊には特異物質の含有、あるいは全体が特異物質で
構成されているものではないか、と、いう点に着眼した
ものである。[0006] In analyzing this buried form, the branches fall off with the bumpy mass attached, and they are submerged in the soil after a long period of time, and even after the branches have decayed to soil, Number 10
It remains unchanged even after a lapse of 0 years, and the presently produced form is produced as it is. Therefore, these lumpy masses contain a specific substance or the whole is composed of a specific substance. It is the one that has been focused on.
【0007】即ち、永年(約1000年とも言われてい
るが真偽の程は不詳)の間、土中での埋没状態にあった
にもかかわらず朽ち果てないで保たれているのは、ある
特別な物質(抗菌作用物質あるいは防腐作用物質)を保
有しているためではないかという可能性に着眼し、その
性質と成分の分析解明にあたった。In other words, for many years (it is said that it is said to be about 1000 years, but the truth is unclear), even though it has been buried in the soil, it remains undiminished. We focused on the possibility of possessing a special substance (antibacterial substance or antiseptic substance) and analyzed and elucidated its properties and components.
【0008】一般に、針葉樹のある種には、ヒノキチオ
ール等の抗菌成分が含有されていることは周知である
が、後述するが、パラナ松のコブ状塊には、その分析の
結果、前記のヒノキチオールは検出されなかった。しか
し、実施例に示すように抗菌作用がみいだされた。In general, it is well known that certain species of coniferous trees contain antibacterial components such as hinokitiol, but as will be described later, the lumpy lumps of Parana pine show that the above-mentioned hinokitiol has been analyzed. Was not detected. However, an antibacterial effect was found as shown in the examples.
【0009】このコブ状塊の従来よりの使用例において
は、抗菌作用を利用した例はない。[0009] In the conventional use example of this lump-shaped mass, there is no example utilizing the antibacterial action.
【0010】この発明では、上記特質(埋没状態にもか
かわらず朽ち果てないで保たれる特性)の究明に勉めた
結果、従前には全く度外視されていた新分野のあらたな
る特性(抗菌効果)の発見に至ったものである。本発明
の目的は、抗菌効果を有する新たなる物質を世に提供す
ることである。In the present invention, as a result of diligent research into the above-mentioned characteristics (characteristics that can be kept intact despite being buried), a new characteristic (antibacterial effect) in a new field that has been completely ignored before. Was the discovery of. An object of the present invention is to provide the world with a new substance having an antibacterial effect.
【0011】[0011]
【課題を解決するための手段】この発明は、上記の目的
を達成させるための手段として、パラナ松の幹から支成
する枝の育成腋部に生成するコブ状塊からの抽出したレ
ジンを抗菌剤とするものである。As a means for achieving the above-mentioned object, the present invention provides an antibacterial agent for a resin extracted from a lump-like mass formed in the axillary part of a branch of a branch of a Parana pine tree. It is used as an agent.
【0012】[0012]
【実施例】本発明で使用するパラナ松レジンは、次の様
にして製造される。EXAMPLES Parana pine resin used in the present invention is manufactured as follows.
【0013】コブ状塊をあるいは望ましくはチップ状に
破砕、これからエチルアルコール等の溶剤でレジン分を
抽出し、その後、溶剤を留去してパラナ松レジンを得
る。The lump-like lumps are crushed, or preferably into chips, and the resin component is extracted with a solvent such as ethyl alcohol, and then the solvent is distilled off to obtain parana pine resin.
【0014】以上のようにして製造したパラナ松レジン
の代表的物性は、一般的には次の様なものである。溶解
性については、アルコール、アセトン、エステルに可
溶、脂肪族炭化水素系、ならびに芳香族系溶剤には不溶
で、熱可塑性を有す。水素イオン濃度は2%エタノール
溶液で5.5ないし6.5、分子量は約400、融点
85ないし90度c、ケン化価 25ないし45、The typical physical properties of the Parana pine resin produced as described above are generally as follows. Regarding solubility, it is soluble in alcohol, acetone and ester, insoluble in aliphatic hydrocarbon solvents and aromatic solvents, and has thermoplasticity. Hydrogen ion concentration is 5.5% to 6.5 in 2% ethanol solution, molecular weight is about 400, melting point
85 to 90 degrees c, saponification value 25 to 45,
【0015】パラナ松レジンの成分は下記と推定され
る。 Secoisolariciresinol (セコイソラリシレジノール) 80.0ないし82.0% Pinoresinol(ピノレジノール) 3.0ないし4.0% Hinokiresinol(ヒノキレジノール) 4.0ないし4.5% Lariciresinol(ラリシレジノール) 2.5ないし3.0% Pinoresinolのモノ及びジメチルエーテル 3.0ないし4.0%The components of Parana pine resin are presumed to be as follows. Secoisolariciresinol 80.0 to 82.0% Pinoresinol (pinoresinol) 3.0 to 4.0% Hinokiresinol 4.0 to 4.5% Lariciresinol 2.5 to 3.0% Mono and dimethyl ether of Pinoresinol 3.0 to 4.0%
【0016】実験例 パラナ松レジンを溶剤で溶かし、培地に混合し寒天平板
法で抗菌作用を調べたところ、下記の結果を得た。 対象物質 学名 最小発育阻止濃度 (ppm) 黒麹黴 Aspergillus niger (アスペルギルスニガー) >500 麹黴(の仲間) Aspergillus terreus(アスペルギルス テレウス) 500 子のう菌亜門 Eurotium tonophlum (ユーロチリウムトノフィラム) 500 青黴 Penicillium citrinum (ペニシリウム シトリヌム) >500 不完全菌類 Penicillium funiculosum (ペニシリウムフニキュロザム) 250 くものすかび Rhizopus stolonifer (リゾプス ストロニフェル) 280 黒かび Cladosporium cladosporioides (クラドスポリウム クラドスポリオイデス) >500 黒酵母 Aureobasidium pullulans (オオレオバシディウムプルランス) 500 けたまかび Chaetomium globosum(ケトミウム グロボースム) >500 赤かび Fusarium moniliforme (フザリウム モニリフォルメ) 1000 黒かび属 Cladosporium sp. (クラドスポリウム属) 500 不完全菌類 Aspergillus restrictus (アスペルギルスレストリクタス) 1000 上空菌 Penicillium frequentas (ペニシリウム フリクエンタス) 500 ケカビ目カミケカビ属(ケカビ) Absia sp.(アブシディア属) 500 ミルク腐敗カビ Geotrichum sp. (ケオトリカム属) 630 不完全菌 Curvularia sp. (カーグラリア属) 1000 不完全菌 Paeclomyces sp. (パエシロマイセス属) 500Experimental Example Parana pine resin was dissolved in a solvent, mixed in a medium and examined for antibacterial activity by the agar plate method. The following results were obtained. Target substance Scientific name Minimum inhibitory concentration (ppm) Aspergillus niger (Aspergillus niger)> 500 Aspergillus terreus (Aspergillus terreus) 500 Ascomycota ascomycetes Eurotium eurotium 500 Blue mold Penicillium citrinum> 500 Incomplete fungus Penicillium funiculosum 250 Penisillium funiculodes spoiled spices Rhizopus spiodorus clodosporois stonifer) Aur eobasidium pullulans 500 Keetomim Chaetomium globosum> 500 Red mold Fusarium moniliformi Cl Cl osp oror (Cladosporium spp.) 500 Incomplete fungus Aspergillus restrictus (Aspergillus restrictus) 1000 Sky fungus Penicillium frequentas (Penicillium frequentus) 500 Bacterial genus Absia sp. (Abscidia) 500 Milk spoilage mold Geotrichum sp. (Chaeotrichum sp.) 630 Incomplete bacterium Curvularia sp. (Carglaria) 1000 Incomplete bacterium Paeclomyces sp. (Genus Paecilomyces) 500
【0017】[0017]
【発明の効果】この発明は以上のように、パラナ松レジ
ンを従来の用途例とは全く異なる分野の抗菌物質として
使用を可能にしたことによって、新たに世に広く貢献す
るものである。INDUSTRIAL APPLICABILITY As described above, the present invention enables the use of parana pine resin as an antibacterial substance in a field completely different from the conventional application examples, and thus contributes widely to the world.
Claims (1)
に生成するコブ状の塊からの抽出したレジンを抗菌剤と
することを特徴とするパラナ松樹脂からの抽出物抗菌
剤。1. An antibacterial agent for an extract from Parana pine resin, characterized in that a resin extracted from a lump-shaped lump formed in the axilla of a branch growing from a trunk of Parana pine is used as an antibacterial agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19687793A JPH0751488B2 (en) | 1993-07-14 | 1993-07-14 | Extract antibacterial agent from Parana pine resin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19687793A JPH0751488B2 (en) | 1993-07-14 | 1993-07-14 | Extract antibacterial agent from Parana pine resin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0725719A true JPH0725719A (en) | 1995-01-27 |
| JPH0751488B2 JPH0751488B2 (en) | 1995-06-05 |
Family
ID=16365142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP19687793A Expired - Lifetime JPH0751488B2 (en) | 1993-07-14 | 1993-07-14 | Extract antibacterial agent from Parana pine resin |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0751488B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6770147B2 (en) | 2000-05-16 | 2004-08-03 | Zuckerforschung Tulln Gesellschaft M.B.H. | Method for the production of sugar or sugar-containing products from sugar-containing vegetable raw materials, sugar and sugar-containing products made by the method, and extraction solution for use in the method |
| WO2015140528A1 (en) * | 2014-03-18 | 2015-09-24 | University Of Surrey | Pathogenic infections |
| WO2021152217A1 (en) * | 2020-01-31 | 2021-08-05 | Woimet Oy | Use of rosin for treatment of plants |
-
1993
- 1993-07-14 JP JP19687793A patent/JPH0751488B2/en not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6770147B2 (en) | 2000-05-16 | 2004-08-03 | Zuckerforschung Tulln Gesellschaft M.B.H. | Method for the production of sugar or sugar-containing products from sugar-containing vegetable raw materials, sugar and sugar-containing products made by the method, and extraction solution for use in the method |
| AT500496A1 (en) * | 2000-05-16 | 2006-01-15 | Tulln Zuckerforschung Gmbh | PROCESS FOR INHIBITING THERMOPHILIC MICROORGANISMS IN SUGAR-CONTAINING MEDIA |
| AT500496B1 (en) * | 2000-05-16 | 2006-06-15 | Tulln Zuckerforschung Gmbh | PROCESS FOR INHIBITING THERMOPHILIC MICROORGANISMS IN SUGAR-CONTAINING MEDIA |
| WO2015140528A1 (en) * | 2014-03-18 | 2015-09-24 | University Of Surrey | Pathogenic infections |
| US10039288B2 (en) | 2014-03-18 | 2018-08-07 | University Of Surrey | Pathogenic infections |
| WO2021152217A1 (en) * | 2020-01-31 | 2021-08-05 | Woimet Oy | Use of rosin for treatment of plants |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0751488B2 (en) | 1995-06-05 |
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