JPH07303694A - Dialysate preparation equipment - Google Patents

Abstract

(57) [Summary] [Purpose] To provide a dialysate preparation device which is capable of preparing a dialysate having an accurately adjusted ratio and is easy to maintain and inexpensive. [Structure] A diluting solution supply line 2 comprising a mixing container 1, a diluting solution supply line 2, and concentrated dialysate supply lines 4 and 5.
Includes a throttle valve 22 and a negative pressure pump 26 downstream thereof. The concentrated dialysate supply lines 4 and 5 are movable partition walls 4.
Constant volume container 4 partitioned into two chambers by 11, 511
Concentrated dialysate container 4 containing 1 and 51 and concentrated dialysate
2, 52, and one chamber 415, 515 of the constant volume containers 41, 51 is connected to the throttle valve 2 via the bypass passage 3.
It is switchably connected to the diluted liquid supply lines 23 and 24 upstream and downstream of the line 2. Since the constant volume container is an airtight container, when the liquid is sucked out from the chambers 415 and 515, the movable partition walls 411 and 511 move toward this chamber, and the concentrated liquid flows into the chambers 416 and 516. ing.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an apparatus for preparing a dialysate, and more particularly to an apparatus for preparing a dialysate capable of mixing a dilute solution and a concentrated dialysate in a simple and accurate ratio.

[0002]

2. Description of the Related Art Conventionally, a dialysate is generally prepared by accurately measuring the amounts of a concentrated dialysate and a diluting solution using a proportional supply pump and supplying them to a mixing tank for mixing. . However, this method has drawbacks such that the apparatus is complicated because the concentrated dialysate and the diluted solution are accurately measured, and the measurement tends to be inaccurate when the mixing ratio is large.

Therefore, in order to solve the above-mentioned drawbacks of the prior art, in a device for mixing and preparing three or more kinds of liquids at an accurate ratio using a closed container having a constant volume, a concentrated liquid connected to the closed container. Line and dilute solution line, concentrated solution metering pump provided between concentrated solution line and hermetic container, and branch valve provided on the suction side of concentrated solution metering pump for selecting two or more kinds of infusate Or a combination of a branch line and a valve provided in each branch line, and the first injection liquid is injected into a closed container by a concentrate measuring pump, and the necessary injection liquid is continuously switched using the same concentrate measuring pump while switching the valve. A mechanism capable of repeating this injection operation for the same number of times as the above, and a mechanism capable of supplying the diluted solution from the diluted solution line at the same time as the injection of the concentrated solution or at the same time until the closed container is filled (special features). Flat 1-23170 JP).

[0004]

However, the one disclosed in Japanese Patent Publication No. 1-23170 is uneconomical and requires a lot of maintenance because it uses a complex and expensive concentrate metering pump. It has drawbacks. Further, when trying to degas the diluted solution, it is uneconomical to install a separate degassing pump in the diluted solution line.
The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a dialysate preparation device that can prepare a dialysate with an accurately adjusted ratio and that is easy to maintain and inexpensive.

[0005]

In order to solve the above-mentioned problems, the present invention provides a constant-volume mixing container for mixing a concentrated dialysate and a diluent, and a diluent connected to the mixing container. A supply line and a concentrated dialysate supply line, wherein the diluted solution supply line is provided with a throttle valve upstream and a negative pressure pump is provided downstream of the throttle valve, and the concentrated dialysate supply line is provided with a movable partition wall. A closed constant volume container partitioned into two chambers is provided, and one chamber of the constant volume container is switchably connected to a dilution liquid supply line upstream and downstream of the throttle valve via a bypass flow path bypassing the throttle valve. The dialysate preparation device is characterized in that the other chamber of the constant volume container is switchably connected to the concentrated dialysate container and the mixing container. Here, the mixing container may be composed of a closed container partitioned into two chambers by a movable partition, and the diluting solution supply line and the concentrated dialysate supply line may be switchably connected to the two chambers of the closed container. The mixing container may be an open container equipped with a liquid level sensor for limiting the liquid storage capacity. In order to connect the constant volume container to the diluting liquid supply line so as to be switchable upstream or downstream of the throttle valve, a switching valve (preferably an electromagnetic switching valve) is provided in the bypass flow passage, and this switching valve is provided with one of the constant volume containers. The chambers may be connected to each other, or two valves may be provided in series in the bypass passage, and one chamber of the constant volume container may be arranged in the bypass passage between the two valves. Also, a second concentrated dialysate supply line may be provided if necessary,
In this case, the second concentrated dialysate supply line may be arranged in parallel with the first concentrated dialysate supply line, and the second concentrated dialysate container may be arranged in parallel with the first concentrated dialysate container. You may connect. In addition, in order to be able to finely adjust the concentration of the dialysate, the constant volume container is divided into three chambers by two diaphragms, and water or silicone oil is put into and taken out from the chamber formed between these two diaphragms. It may be freely filled to form a movable partition wall.

[0006]

In the dialysate preparation system of the present invention, the capacity of the mixing container is constant, a throttle valve is provided upstream of the mixing vessel, and a dilute solution supply line provided with a negative pressure pump is provided downstream of the throttle valve. A constant volume container partitioned into two chambers by a partition wall is provided, and one chamber of this constant volume container has a diluting liquid supply line upstream and downstream of the throttle valve via a bypass passage bypassing the throttle valve of the diluting liquid supply line. It consists of a concentrated dialysate supply line that is switchably connected to the other, and the other chamber of the constant volume container is switchably connected to the concentrated dialysate container and the mixing container. While being continuously supplied to the mixing container through the line, when the diluting liquid supply line is connected to one chamber of the constant volume container of the concentrated dialysate supply line via the bypass flow path, the flow rate of the diluting liquid is limited by the throttle valve. Done Because there, part of the diluted liquid supplied from the water source flows into one chamber of constant volume container. At this time,
When the other chamber is connected to the mixing container, the movable partition of the constant volume container moves toward the other chamber, and the diluting solution (the one filled during priming) in the other chamber flows out. And is supplied to the mixing container through the concentrated dialysate supply line. The inflow of dilute solution and the outflow of concentrated dialysate continue until the movable partition comes into close contact with the inner wall of the constant volume container on the other chamber side (at this time, one chamber becomes full). When one chamber becomes full, the internal pressure of the flow passage connecting the bypass flow passage and the one chamber suddenly increases.At this time, one chamber is switched to the connection with the diluted solution supply line downstream of the throttle valve, and the other When the chamber is switched to the connection with the concentrated dialysate container, the diluted solution introduced into one chamber is sucked into the diluted solution supply line downstream of the throttle valve by the negative pressure pump, while the concentrated dialyzed solution is introduced into the other chamber. The concentrated dialysate flows from the liquid container. The introduction of the concentrated dialysate continues until the movable partition comes into close contact with the inner wall of one chamber side of the constant volume container, but when the other chamber becomes full, the internal pressure of the flow channel connecting the bypass flow channel and one chamber suddenly increases. At this time, the connection between one chamber and the diluted solution supply line is switched from the downstream side of the throttle valve to the upstream side, and the connection between the other chamber and the concentrated dialysate container is switched to the mixing container. Since the diluted solution is introduced into the chamber and the movable partition wall is moved toward the other chamber, the concentrated dialysate introduced into the other chamber is extruded and supplied to the mixing container.

Here, if the volume of the mixing container is determined so that the ratio of the concentrated dialysate to the diluent becomes a predetermined value when the container is full, the dilution water is continuously supplied until it becomes full. By supplying a predetermined amount of concentrated dialysate in the meantime, a precisely adjusted dialysate can be obtained. The amount of the concentrated dialysate supplied to the mixing container is determined by the capacity of the constant volume container, but the movable partition wall is divided into, for example, the constant volume container into three chambers with two diaphragms, and between these two diaphragms. If you fill the chamber with water or silicone oil in and out freely, you can adjust the volume of the constant volume container by taking in and out water or silicone oil. It can be adjusted.

[0008]

Embodiments of the present invention will now be described with reference to the drawings. FIG. 1 is a system diagram of a dialysate preparation apparatus according to one embodiment of the present invention, FIG. 2 is a system diagram showing another embodiment, and FIG. 3 is a system diagram showing yet another embodiment. As shown in FIGS. 1 and 2, the dialysate preparation apparatus of the present invention comprises a mixing container 1, a dilute solution supply line 2, and a concentrated dialysate supply lines 4, 5.
The dilution liquid supply line 2 includes a throttle valve 22 and a negative pressure pump 26 downstream thereof. The concentrated dialysate supply lines 4 and 5 are fixed volume containers 41 and 51 partitioned into two chambers 415, 416; 515 and 516 by movable partition walls 411 and 511, and a concentrated dialysate container 42 containing the concentrated dialysate. One of the chambers 415 and 515 of the constant volume containers 41 and 51, which includes a constant volume container 41 and 51, is connected to the upstream and downstream dilution liquid supply lines 23 and 24 via the bypass passage 3 that bypasses the dilution liquid passing through the throttle valve 22. And is switchably connected. Since the constant volume containers 41 and 51 are hermetically sealed containers, when the liquid flows into the chambers 415 and 515, the movable partition wall 4
11, 511 moved to the side of the chambers 416, 516,
When the liquid filled in 6, 516 is pushed out and the liquid is sucked out from the chambers 415, 515, the movable partition wall 41
1, 511 are moved to the side of the chambers 415, 515, and the chambers 416,
The liquid flows into 516.

The dialysate preparation apparatus of the present invention will be described in detail below mainly with reference to FIG. In FIG. 1, 1
Is a mixing container, 11 is a movable partition (diaphragm), 12,
13 is a chamber of the mixing container partitioned by the diaphragm 13, 14 and 15 are solenoid valves, 16 is a dialysate line,
2 is a dilute solution supply line, 21 is a dilute solution supply source, 22 is a throttle valve, 23 and 24 are dilute solution supply lines upstream and downstream of the throttle valve 22, 25 is a heater, 26 is a negative pressure pump, and 27 is a remover. Air tank, 28 is pressure sensing means, 241,
Reference numeral 242 is a line connecting the dilution liquid supply line 2 and the chambers 12 and 13 of the mixing container 1, 243 and 244 are electromagnetic valves, 3 is a bypass flow path bypassing the throttle valve 22, 31
Is an electromagnetic switching valve, 32 and 33 are electromagnetic switching valve 31 and chambers 415 and 515 of one of constant volume containers 41 and 51 described later.
A line for connecting with, 34 is a pressure sensing means, 35, 36
Are bypass flow paths upstream and downstream of the electromagnetic switching valve 31. 4,5 are concentrated solutions containing calcium salt and magnesium salt (liquid A) and concentrated solutions containing bicarbonate (B), respectively.
A concentrated dialysate supply line for supplying a concentrated dialysate element called "liquid" (a solution, a solution B, and a diluting water are mixed to form a dialysate), and 41 and 51 are constant volume containers.
411 and 511 are movable partition walls, and silicone oil (may be water or the like) 414 and 514 are removably filled between the two diaphragms 412, 413 and 512, 513. Also, 415, 416; 515, 5
Reference numeral 16 is a chamber partitioned by movable partition walls 411 and 511, 417 and 517 are opening / closing valves, 418 and 518 are liquid suction and discharge means, and 42 and 52 are concentrated dialysate containers for storing A solution and B solution, respectively. Lines 43 and 53 connect the concentrated dialysate containers 42 and 52 to the mixing container 1, respectively (in FIG. 1, they are connected to the diluted solution supply line 24 downstream of the negative pressure pump 26 and downstream of the deaeration tank 27), 44, 5
4 is the other chamber 416 of the constant volume containers 41 and 51,
516 and the lines 43 and 53 through the concentrated dialysate containers 42 and 52
And a line connecting switchably to the mixing container 1, 45,
Reference numerals 46, 55 and 56 are solenoid valves.

The dilute solution supply line 2 is a circuit that connects the dilute solution supply source 21 and the mixing container 1, and includes a throttle valve 22 and a negative pressure pump 26. The bypass flow path 3 extends across the throttle valve 22. Are connected. And the diluted liquid supply source 2
A part of the diluted solution supplied from 1 passes through the diluted solution supply line 23 upstream of the throttle valve 22 and the bypass flow path 35 upstream of the electromagnetic switching valve 31, and one chamber 415, 515 of the constant volume containers 41, 51. Flow into the diluted liquid supply line 24 downstream from the throttle valve 22 through the bypass flow passage 36 downstream from the electromagnetic switching valve 31 by switching the electromagnetic switching valve 31. There is.

From the diluted solution supply source 21 to the diluted solution supply line 2
The flow rate of the diluted liquid supplied to (1) is restricted by the throttle valve 22 and is supplied to the mixing container 1 having a constant volume through the heater 25, the negative pressure pump 26, and the deaeration tank 27. The mixing container 1 may be one chamber, but is normally divided into two chambers 12 and 13 by a movable partition wall, for example, a diaphragm 11 made of a flexible resin, as shown in FIG. 1, so as to perform continuous mixing. The chambers 12 and 13 are provided with solenoid valves 243 and 244, respectively, and branch lines 241 and 242 of the diluted solution supply line 2 are provided.
Is connected and switchable. In order to connect the diluted solution supply line 2 and the chambers 12 and 13 in a switchable manner, an electromagnetic switching valve (not shown) is provided downstream of the diluted solution supply line 2 and branch lines 241 and 242 are provided thereto. You may connect. The throttle valve 22 limits the flow rate of the diluting liquid (usually tap water or RO water is used) from the diluting liquid supply source 21 to make the internal pressure upstream of the throttle valve 22 positive.
It is for making the internal pressure on the downstream side of 2 negative, and normally a constant flow valve with a stable flow rate is used. Also, the heater 25
Is to adjust the dialysate to a physiological temperature by warming the diluted solution. As shown in FIG. 1, when the deaeration tank 27 is provided in the downstream of the negative pressure pump 26, the diluted solution is heated. As a result, the efficiency of deaeration by the deaeration pump (in this embodiment, the negative pressure pump 26 also serves as a deaeration pump) and the deaeration tank 27 is improved.

The dialysate, the flow rate of which is restricted by the throttle valve 22, is used as the diluent supply lines 23 and 2 upstream and downstream of this valve.
By-pass flow path 3 connected to 4 allows bypass to constant volume containers 41 and 51 of concentrated dialysate supply lines 4 and 5. The electromagnetic switching valve 31 is a constant volume container 41, 5
1 and the diluted liquid supply lines 23 and 24 upstream and downstream of the throttle valve 22 are switchably connected. A switchable connection between the constant volume containers 41, 51 and the diluted solution supply lines 23, 24 upstream and downstream of the throttle valve 22 is provided with two solenoid valves (not shown) in the bypass passage 3.
Is provided, and the constant volume containers 41, 51 are provided between the two solenoid valves.
It is also possible to connect. The constant volume containers 41 and 51 are partitioned into two chambers by movable partition walls 411 and 511. When the upstream diluted solution supply line 23 and the constant volume containers 41, 51 are connected, the diluted solution passes through the bypass flow path 35, the electromagnetic switch valve 31, and the lines 32, 33 upstream of the electromagnetic switching valve 31, and the fixed volume containers 41, 51. Into one of the chambers 415, 515. Lines 32 and 33 when chambers 415 and 515 are full
Since the internal pressure in the inside suddenly increases, the pressure sensing means 34 such as a pressure switch or a flow switch provided in the lines 32 and 33 senses a large variation in the internal pressure and sends a flow path switching signal to the electromagnetic switching valve 31. When the connection with the volume containers 41 and 51 is switched from the diluted solution supply line 23 upstream of the throttle valve 22 to the diluted solution supply line 24 downstream of the throttle valve 22 in response to the flow path switching signal from the pressure sensing means 34, the diluted solution downstream. The supply line 24 is provided with a negative pressure pump 26 for sucking the diluted solution filled in the chambers 415 and 515 of the constant volume containers 41 and 51 together with the diluted solution from the upstream diluted solution supply line 23. , Lines 3 for diluted water in chambers 415 and 515
2, 33, bypass passage 36 downstream of the electromagnetic switching valve 31
Flow into the diluted solution supply line 24 at the downstream side through the heater 2 together with the diluted solution from the diluted solution supply line 23 at the upstream side.
5. Mixing container 1 via negative pressure pump 26 and deaeration tank 27
Is supplied to.

The concentrated dialysate supply lines 4 and 5 include constant volume containers 41 and 51 and concentrated dialysate containers 42 and 52, and a line 44, respectively.
54, lines 43, 53 with two solenoid valves 45, 46; 55, 56, and constant volume vessels 41, 51
Via lines 44, 54 solenoid valves 45, 46; 55,
It is connected to the lines 43 and 53 between 56. With this configuration, the constant volume containers 41 and 51 are switchably connected to the mixing container 1 and the concentrated dialysate containers 42 and 52. The switchable connection between the constant volume containers 41, 51 and the mixing container 1 and the concentrated dialysate containers 42, 52 is provided with electromagnetic switching valves (not shown) in the lines 43, 53, and the constant volume containers 41, It is also possible to connect 51. The constant volume containers 41 and 51 are partitioned by movable partition walls 411 and 511 into chambers 415 and 515 for taking in and out a diluting solution and chambers 416 and 516 for taking in and out a concentrated dialysate, respectively.
The capacities of 15, 515 and the chambers 416, 516 are adapted to increase or decrease according to the movement of the movable partition walls 411, 511. As the movable partition walls 411 and 511, two diaphragms 412 and 41 made of a flexible resin as shown in FIG. 1 are used.
3; 512, 513 may be used in which a chamber partitioned by 512, 513 is filled with silicon oil, water, or the like so that it can be freely taken in and out. In this case, the silicone oil or the like is used for opening / closing valves 417, 5
By opening 17 and taking it in and out using a liquid suction / discharge means such as a syringe, the amount of concentrated dialysate introduced into the chambers 416, 516 can be adjusted.

The concentrated dialysate is supplied from the concentrated dialysate containers 42 and 52 once to the other chambers 416 and 516 of the constant volume containers 41 and 51.
Is housed in this room 416, 516 and lines 44, 5
4 and lines 43, 53 through chamber 1 of mixing container 1
2 or 13 is supplied. here,
As shown in the figure, the lines 43 and 53 may be connected to the diluted solution supply line 24 downstream of the negative pressure pump 26 (downstream of the deaeration tank when the deaeration tank 27 is present). Here, since the constant volume containers 41 and 51 are hermetically sealed containers, the chamber 415,
When liquid flows into 515, the movable partition walls 411 and 511 move to the chamber 4.
16, the liquid filled therein is pushed out, and when the liquid is sucked out from the chambers 415, 515, the movable partition walls 411, 511 move to the chambers 415, 515 side, and the chamber 416, The liquid flows into 516. Movable partition walls 411 and 5 having variable capacities as shown in FIG.
In the case of No. 11, it is possible to adjust the mixing ratio of the concentrated dialysate by sucking and discharging the silicone oil or the like filled inside with the liquid suction / discharge means 418, 518.

The solenoid valves 45 and 55 are opened, and the solenoid valves 46 and 55 are opened.
56 is closed and the other chamber 41 of the constant volume containers 41, 51 is closed.
When the diluting solution flows into one of the chambers 415 and 515 in a state where the diluting solution supply line 2 is connected to the chambers 516 and 516, the movable partition walls 411 and 511 move to the left side in FIG. The dialysate is extruded from the chamber through the line 43 and the dilute solution supply line 2 to the chamber 1 of the mixing container 1.
2 or 13. Further, the solenoid valves 45 and 55 are closed, and the solenoid valves 46 and 56 are opened, so that the constant volume container 41,
The other chamber 416, 516 of 51 and the concentrated dialysate container 42,
When the diluting solution is sucked out from one of the chambers 415 and 515 in the state in which 52 is connected, the movable partition walls 411 and 511 are closed.
Since it moves to the right side in, the concentrated dialysate containers 42, 5
The concentrated dialysate in 2 is drawn off and flows through the lines 44, 54 into the chambers 416, 516.

The diluted solution and concentrated dialysate are supplied to the chamber 12 or 13 of the mixing container 1 as described above. When the chamber 12 or 13 becomes full, the internal pressure of the downstream diluted solution supply line 24 is suddenly increased. Since it rises, the pressure sensing means 28 such as a pressure switch senses this and the solenoid valves 243, 24
Send the switching signal to 4. For example, if the chamber 12 is being supplied with concentrated dialysate and it is full, the solenoid valve 2
43 is closed and the solenoid valve 244 is opened to open branch lines 241 and 2
42 is switched and the supply of concentrated dialysate is switched from chamber 12 to chamber 13. And at this time, the branch line 24
Simultaneously with the switching of 1 and 242, the solenoid valve 14 connected to the filled chamber 12 is opened, the solenoid valve 15 connected to the chamber 13 is closed, and the dialysate filled in the chamber 12 is dialyzed. To be supplied to.

As shown in FIG. 2, the mixing container 10 in FIG. 1 is an open container equipped with a liquid level sensor 101 such as a float switch, and the concentrated dialysate and diluting liquid supplied to the mixing container 10 by the liquid level sensor 101. In order to limit the total amount of the dialysate to a fixed amount, a dialysate preparation apparatus constituted by only main elements is shown for simplicity. In the figure, 102 is a solenoid valve, 103 is a storage container, 104 is a dialysate supply pump, 20 is a diluted solution supply line, 201 is a diluted solution supply source,
202 is a throttle valve, and 203 and 204 are throttle valves 20, respectively.
2, a diluted solution supply line upstream and downstream of 2, a negative pressure pump 206, and a solenoid valve 209. Further, 30 is a bypass flow passage, 301 and 302 are electromagnetic valves, 303 is a line connecting one chamber 404 of the constant volume container 401 described later and the bypass flow passage 30, 304 is pressure sensing means, and 305 and 306 are electromagnetic respectively. 40 is a bypass flow path upstream of the valve 301 and downstream of the solenoid valve 302, 40 is a concentrated dialysate supply line,
401 is a constant volume container, 402 is a concentrated dialysate container, 403
Is a line connecting the concentrated dialysate container 402 and the mixing container 10, 404 is a movable partition wall, and 405 and 406 are movable partition walls 40.
4 is a chamber partitioned by 4, 407 is an electromagnetic switching valve, 408
Is the other chamber 406 of the constant volume container 401 and the electromagnetic switching valve 40.
It is a line that connects the six.

The diluted solution supplied from the diluted solution supply source 201 to the diluted solution supply line 20 is supplied to the mixing container 1 through the negative pressure pump 206, the flow rate of which is restricted by the throttle valve 202. The mixing container 1 is an open container, and a liquid level sensor 101 such as a float switch is provided inside the mixing container 1 in order to limit the storage capacity of the supplied liquid to a fixed amount.

The diluting liquid whose flow rate is restricted by the throttle valve 202 is concentrated dialysis by the bypass flow passage 30 connected to the diluting liquid supply lines 203 and 204 upstream and downstream of this dialysate as in the dialysate preparation apparatus of FIG. It can be bypassed to the constant volume container 401 of the liquid supply line 40. Constant volume container 401 and upstream and downstream dilution liquid supply lines 20
As shown in the figure, the switchable connection with 3, 204 is provided with two solenoid valves 301, 302 in the bypass flow passage 301, and a constant volume container 401 is connected between these two solenoid valves to connect the valve 301, Instead of alternately opening and closing 302, an electromagnetic switching valve (31 of FIG. 1 is provided in the bypass flow passage 301.
(Refer to FIG. 4), and one chamber 40 of the constant volume container 401 is provided therein.
5 may be connected. The constant volume container 401 is partitioned into two chambers by a movable partition wall 404 made of, for example, a flexible resin diaphragm. Open the solenoid valve 301 and open the solenoid valve 30.
When 2 is closed and the upstream dilute solution supply line 203 and the constant volume container 401 are connected, the dilute solution is supplied to the upstream bypass passage 30.
5, solenoid valve 301, line 303 through constant volume container 4
01 into one chamber 405. When the chamber 405 becomes full, the internal pressure in the line 303 suddenly increases. Therefore, the pressure sensing means 304 provided in the line 303 detects a large variation in the internal pressure and sends a signal for switching the flow paths to the solenoid valves 301 and 302. In response to the flow path switching signal from the pressure sensing means 304, the solenoid valve 301 is closed and the solenoid valve 302 is opened, and the connection of the constant volume container 401 with the one chamber 405 is supplied from the diluted solution supply line 203 on the upstream side to the diluted solution supply on the downstream side. Switched to line 204. Then, the negative pressure pump 206 is provided in the diluted solution supply line 204 on the downstream side, and the constant volume container 401 is provided together with the diluted solution from the diluted solution supply line 203 on the upstream side.
Since the diluted solution filled in the chamber 405 of the
The diluted solution in 5 passes through the line 303, the electromagnetic valve 302, and the bypass flow path 306 at the downstream side, and the diluted solution supply line 20 at the downstream side.
4 and is supplied to the mixing container 1 through the negative pressure pump 206 together with the diluted solution from the upstream diluted solution supply line 203.

The concentrated dialysate supply line 40 has a constant volume container 4
01 and a concentrated dialysate container 402, a line 403 connecting the concentrated dialysate container 402 and the mixing container 10, an electromagnetic switching valve 407 provided in the line 403, and the other chamber 406 of the constant volume container 401 and an electromagnetic switching valve 407. Line 408
The constant volume container 401 is composed of an electromagnetic switching valve 407.
Is connected to the concentrated dialysate container 402 and the mixing container 10 in a switchable manner. The switchable connection between the constant volume container 401 and the concentrated dialysate container 402 and the mixing container 10 is such that two solenoid valves (45, 4 in FIG.
6) is provided, and the constant volume container 4 is provided between the two solenoid valves.
It is also possible to connect 01 to line 403. The constant volume container 401 is partitioned by a movable partition wall 404 into a chamber 405 for taking in and out a diluting solution and a chamber 406 for taking in and out a concentrated dialysate. Movable partition 404
It is designed to increase or decrease according to the movement of. The function of the concentrated dialysate supply line 40 is the same as in the case of FIG.

When the amounts of the diluted solution and the concentrated dialysate supplied to the mixing container 10 become constant, the liquid level sensor 101 such as a float switch detects the amount and the solenoid valve 2
09, 301, 302 and the negative pressure pump 206 are sent a signal to stop the supply of the diluent. At this time, naturally, the supply of the concentrated dialysate is also stopped. Then, the solenoid valve 102 is opened, the dialysate prepared in the mixing container 10 is supplied to the liquid storage container 103, and is used for dialysis treatment as needed.

As shown in FIG. 3, instead of providing the second concentrated dialysate supply line 5 in FIG. 1, a second concentrated dialysate container 47 is provided in the concentrated dialysate supply line 4 in parallel with the concentrated dialysate container 42. Is provided. In the figure, 48 is a solenoid valve, 6 is a cleaning line, 61 is a solenoid valve, and the same components are denoted by the same reference numerals as those in FIG. In this dialysate preparation device, since the concentrated dialysate containers 42 and 47 are connected in parallel to the constant volume container 41, the solenoid valves 46 and 48 are switched and used depending on the supplied concentrated dialysate. Therefore, it is necessary to wash the concentrated dialysate supply line 4 each time before switching the solenoid valves 46 and 48. The cleaning line 6 is for that purpose and is connected to the bypass flow passage 35 upstream of the electromagnetic switching valve 31. The cleaning line 6 does not necessarily have to be provided for cleaning the concentrated dialysate supply line 4, and for example, the electromagnetic switching valve 31 and the electromagnetic valve 4 can be used.
6, 48, 243, 244 may be closed to allow the diluent to flow. To clean the concentrated dialysate supply line 4,
Chamber 415 of constant volume container 41 and diluted solution supply line 2 downstream
4 and the solenoid valves 45, 46 and 48 are closed, and the solenoid valve 6
1 is opened to fill the concentrated dialysate supply line 4 with the diluting solution, then the solenoid valve 61 is closed, and the chamber 4 of the constant volume container 41 is closed.
15 is connected to the upstream diluted solution supply line 23, and the solenoid valve 4
Just open 5. At this time, the diluted solution filled in the concentrated dialysate supply line 4 is pushed out to the mixing container 1 by the diluted solution flowing into the chamber 415 of the constant volume container 41.

[0023]

As is apparent from the above description, the dialysate preparation apparatus of the present invention has a simple mechanism, and therefore can be miniaturized and is economical. In addition, maintenance is easy. Further, the negative pressure pump is used to supply the concentrated dialysate, and the negative pressure pump can be used as a degassing pump when degassing the dialysate, so that a separate degassing pump is not required.

[Brief description of drawings]

FIG. 1 is a system diagram of a dialysate preparation device according to an embodiment of the present invention.

FIG. 2 is a system diagram showing another embodiment of the present invention.

FIG. 3 is a system diagram showing still another embodiment of the present invention.

[Explanation of symbols]

 1 Mixing Container 11 Diaphragm (Movable Partition) 103 Storage Container 2, 20 Diluting Solution Supply Line 22, 202 Throttle Valve 26, 206 Negative Pressure Pump 3, 30 Bypass Flow Path 31 Electromagnetic Switching Valve 4, 5, 40 Concentrated Dialysate Supply Lines 41, 51, 401 Constant volume containers 411, 511, 404 Movable partition walls 42, 52, 47, 402 Concentrated dialysate container 6 Washing line

Claims (8)

[Claims] 1. A diluting solution comprising: a mixing container having a constant volume for mixing the supplied concentrated dialysate and the diluted solution; and a dilute solution supply line and a concentrated dialysate supply line connected to the mixing container. The supply line is provided with a throttle valve upstream and a negative pressure pump is provided downstream of the throttle valve, and the concentrated dialysate supply line is provided with a closed constant volume container partitioned into two chambers by a movable partition wall. One chamber is switchably connected to the dilution liquid supply line upstream and downstream of the throttle valve via a bypass flow path that bypasses the throttle valve, and the other chamber of the constant volume container is a concentrated dialysate container and A dialysate preparation device, which is switchably connected to a mixing container. 2. The mixing container is a closed container partitioned into two chambers by a movable partition, and a dilute solution supply line and a concentrated dialysate supply line are switchably connected to the two chambers of the closed container. The dialysate preparation device according to. 3. The dialysate preparation apparatus according to claim 1, wherein the mixing container is an open container equipped with a liquid level sensor for limiting a liquid storage capacity. 4. The dialysate preparation apparatus according to claim 1, wherein a switching valve is provided in the bypass flow passage, and one chamber of the constant volume container is connected to the switching valve. 5. A bypass passage is provided with two valves in series,
The dialysate preparation device according to any one of claims 1 to 3, wherein one chamber of the constant volume container is connected to the bypass flow path between the two valves. 6. The dialysate preparation device according to claim 4, wherein a second concentrated dialysate supply line is arranged in parallel with the concentrated dialysate supply line. 7. The dialysate preparation device according to claim 4, wherein a second concentrated dialysate container is arranged in parallel with the concentrated dialysate container. 8. A movable partition divides the constant volume container into three chambers.
The dialysate preparation apparatus according to claim 1, wherein the chamber is formed between a plurality of diaphragms, and the chamber is filled with water or silicone oil so that it can be taken in and out freely.