JPH0784476B2 - 凝血カスケードに対して治療活性を有する新規ペプチドおよびプソイドペプチド化合物 - Google Patents

凝血カスケードに対して治療活性を有する新規ペプチドおよびプソイドペプチド化合物

Info

Publication number
JPH0784476B2
JPH0784476B2 JP5006101A JP610193A JPH0784476B2 JP H0784476 B2 JPH0784476 B2 JP H0784476B2 JP 5006101 A JP5006101 A JP 5006101A JP 610193 A JP610193 A JP 610193A JP H0784476 B2 JPH0784476 B2 JP H0784476B2
Authority
JP
Japan
Prior art keywords
glu
phe
tyr
abo
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP5006101A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05286996A (ja
Inventor
− リュク フォシュル ジャン
ツリュ クリストフ
ヴェルビュラン トニイ
パラディノ ジョゼフ
Original Assignee
アディール エ コンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アディール エ コンパニー filed Critical アディール エ コンパニー
Publication of JPH05286996A publication Critical patent/JPH05286996A/ja
Publication of JPH0784476B2 publication Critical patent/JPH0784476B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP5006101A 1992-01-15 1993-01-18 凝血カスケードに対して治療活性を有する新規ペプチドおよびプソイドペプチド化合物 Expired - Lifetime JPH0784476B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9200340 1992-01-15
FR9200340A FR2686086A1 (fr) 1992-01-15 1992-01-15 Nouveaux derives de peptides et de pseudopeptides therapeutiquement actifs dans la cascade de coagulation sanguine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
JPH05286996A JPH05286996A (ja) 1993-11-02
JPH0784476B2 true JPH0784476B2 (ja) 1995-09-13

Family

ID=9425635

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5006101A Expired - Lifetime JPH0784476B2 (ja) 1992-01-15 1993-01-18 凝血カスケードに対して治療活性を有する新規ペプチドおよびプソイドペプチド化合物

Country Status (8)

Country Link
US (1) US5371071A (2)
EP (1) EP0552999A1 (2)
JP (1) JPH0784476B2 (2)
AU (1) AU658255B2 (2)
CA (1) CA2087328A1 (2)
FR (1) FR2686086A1 (2)
NZ (1) NZ245679A (2)
ZA (1) ZA93274B (2)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710917B1 (fr) * 1993-10-07 1995-11-24 Adir Nouveaux dérivés de peptides thérapeutiquement actifs dans la cascade de coagulation sanguine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
CN1498224A (zh) * 2000-07-21 2004-05-19 ���鹫˾ 用作丙型肝炎病毒ns3-丝氨酸蛋白酶抑制剂的新型肽

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649697A1 (fr) * 1989-07-11 1991-01-18 Oreal Nouveaux derives d'urethanne, leur preparation et leur application notamment comme agents hydratants dans des compositions cosmetiques ou pharmaceutiques destinees au traitement des peaux seches
ZA915658B (en) * 1990-07-24 1992-05-27 Merrell Dow Pharma Analogs of hirudin having antiplatelet activity

Also Published As

Publication number Publication date
US5371071A (en) 1994-12-06
FR2686086B1 (2) 1995-06-02
CA2087328A1 (fr) 1993-07-16
NZ245679A (en) 1995-06-27
AU3117093A (en) 1993-07-22
EP0552999A1 (fr) 1993-07-28
AU658255B2 (en) 1995-04-06
JPH05286996A (ja) 1993-11-02
ZA93274B (en) 1993-08-23
FR2686086A1 (fr) 1993-07-16

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