JPH087085A - Picture forming device - Google Patents

Abstract

PURPOSE:To form picture data into a CRT picture by synthesizing it so that the said picture can be scrolled at high speed. CONSTITUTION:A picture forming device is provided with a temporary memory 66 to store the picture data stored in a picture data storage means 40 while developing it two-dimensionally, a magnified/reduced picture data storage part 72 to store temporarily the said picture data while developing it two- dimensionally after magnifying or reducing it, a graphic data storage part 74 to store graphic data, a data synthesizing part 76 to select true picture data from among the stored graphic data, and synthesize it with the picture data developed two-dimensionally and stored temporarily in the magnified/reduced picture data storage part, a synthesized picture data storage part 78 to store the synthesized picture data and graphic data while developing them two- dimensionally, a data area selecting part 77 to select a part of the synthesized data storage part, a window memory 79 to store it temporarily while developing it two-dimensionally, and a picture display part 90 to display that data on a CRT.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an image forming apparatus, and more particularly to an image forming apparatus capable of improving observation analysis characteristics of an arbitrary image area.

[0002]

2. Description of the Related Art A substance labeled with a radiolabel is administered to an organism, and the organism or a part of the tissue of the organism is used as a sample, and the sample is used as a radiation film such as a high-sensitivity X-ray film. By overlapping for a certain time,
The radiographic film is exposed or exposed, and the position information of the radiolabeled substance in the sample is obtained based on the exposed part of the radiographic film. Numerator
A chemiluminescent substance is contacted with a chemiluminescent substance, and the chemiluminescent substance is selectively labeled with a labeling substance, and the macromolecule selectively labeled with the labeling substance is contacted with the chemiluminescent substance to label the chemiluminescent substance. By detecting chemiluminescence in the visible light wavelength range caused by contact with a substance, a chemiluminescence detection method for obtaining information on macromolecules such as genetic information, irradiating a metal or non-metal sample with an electron beam,
An electron that detects an image of a biological tissue by performing elemental analysis, composition analysis of the sample, structural analysis of the sample, etc. by detecting a diffraction image or transmission image of the sample, and irradiating the biological tissue with an electron beam. A detection method using a microscope, a radiation diffraction image detection method of irradiating a sample with radiation, detecting the obtained radiation diffraction image, and performing structural analysis of the sample are known.

These methods have hitherto been used as detection materials.
Using a photographic film, a radiographic image on the photographic film,
This was done by recording a chemiluminescence image, an electron microscope image, a radiation diffraction image, etc., and visually detecting the visible image. However, when a photographic film is used as the detection material, an autoradiography detection method is used. And the radiation diffraction image detection method have a problem that the sensitivity of the radiation film is low and it takes a long time to record an image.The chemiluminescence detection method reliably detects weak chemiluminescence. In order to do so, it is necessary to use a high-sensitivity film with a high γ value, but when using a high-sensitivity film with a high γ value, be sure to use the linear portion of the characteristic curve,
It is difficult to expose, there are many exposure mistakes, there is a problem that it is necessary to repeat exposure by changing the exposure conditions. Furthermore, in the detection method with an electron microscope, The film has a small number of linear parts of the characteristic curve, so it is difficult to select the exposure conditions, and there is the problem that repeated exposure is required due to an exposure error. However, there is a problem that the manual processing is indispensable and the operation is complicated.

Therefore, when radiation, visible light, or an electron beam is irradiated instead of the conventional photographic film, the energy is absorbed and accumulated, and then excited by using an electromagnetic wave in a specific wavelength range. Then, the emitted radiation, visible light,
The photostimulable phosphor having the characteristic of emitting photostimulable light in an amount corresponding to the amount of energy such as electron beam was used as a detection material for radiation, visible light, electron beam, etc., and was emitted from the photostimulable phosphor. The stimulated emission is photoelectrically detected, converted into a digital signal, and the obtained image data is subjected to predetermined image processing, and then the image is reproduced on a display means such as a CRT screen or a photographic film. The proposed autoradiography detection method, chemiluminescence detection method, electron microscope detection method, and radiation diffraction image detection method are proposed (for example, Japanese Patent Publication No. 1-60784 and Japanese Patent Publication No. 1-6078).
No. 2, Japanese Patent Publication No. 4952/1992, US Pat. No. 5,
No. 028,793, GB Patent Publication No. GB 2,24
6,197A, JP-A-61-51738, JP-A-61-93538, JP-A-59-15843). According to the detection method using this stimulable phosphor, not only the chemical treatment called development processing is unnecessary, but also in the autoradiography detection method and the radiation diffraction image detection method, the exposure time is significantly increased. The chemiluminescence detection method and the detection method using an electron microscope have the advantages that there are few exposure mistakes and that exposure can be performed easily. Since the image is reproduced later, it is preferable that the image data is subjected to signal processing so that the image can be reproduced as desired or quantitative analysis by a computer can be performed.

[0005]

As described above, when the image data converted into an electric signal by using the stimulable phosphor sheet is reproduced as a visible image on a display means such as a CRT screen and is observed and analyzed. In some cases, it may be necessary to magnify and display an image region to be observed and analyzed on a CRT or the like. However, for that reason, using a memory for storing the entire enlarged image data requires an extremely large-capacity memory and is not efficient. In order to solve such a problem, a first memory for two-dimensionally developing image data and temporarily storing it is provided, and a part of the image data stored in this first memory is provided. It is necessary to provide the image data selection means for selecting, select a part of the image data, and then expand and store the second memory. However, when reproducing image data as an image by a CRT or the like and performing observation analysis, the image region to be observed and analyzed is specified and its characteristics are detected, or the image data in the image region is detected. For the purpose of performing predetermined signal processing, it is often necessary to display various figures together with an image on a CRT or the like. In such a case, further,
Combine the figure data with the image data, and in the third memory,
It is necessary to develop the data two-dimensionally and temporarily store it, and display the data two-dimensionally developed and temporarily stored in the third memory by a CRT or the like.

As described above, in the image forming apparatus for displaying the image corresponding to a part of the image data on the display means such as the CRT screen, the image is displayed on the CRT so that the image area to be observed and analyzed is displayed. It is indispensable to scroll the displayed image, but in such an image forming apparatus, in order to scroll the image displayed on the CRT or the like, the image data selecting means is accessed to access the first memory. There is no choice but to select a part of the image data stored in, store it in the second memory, synthesize the graphic data, store it in the third memory, and display it on a CRT or the like. However, there is a problem that an image displayed on a CRT or the like cannot be scrolled at high speed. This means that an autoradiography image, a chemiluminescence image, an electron microscope image, a radiation diffraction image, etc. are once recorded on a photographic film, the recorded image is photoelectrically read, and a digital signal is obtained. To the signal,
By performing the desired signal processing, C
The same problem occurs when reproducing on a display means such as an RT screen.

[0007]

It is an object of the present invention to provide an image forming apparatus for forming a visible image on a CRT screen on the basis of image data.
An object of the present invention is to provide an image forming apparatus capable of scrolling an image formed on a display means such as a T screen at high speed.

[0008]

SUMMARY OF THE INVENTION An object of the present invention is to provide an image data storage means for storing image data, and a temporary memory for two-dimensionally expanding the image data stored in the image data storage means and temporarily storing it. Means, image data selecting means for selecting image data from the image data which is two-dimensionally expanded in the temporary memory means and temporarily stored, and image data selected by the image data selecting means. Image data enlarging / reducing means for enlarging or reducing, and enlarging / reducing image data storing means for two-dimensionally expanding the image data enlarged or reduced by the image data enlarging / reducing means and temporarily storing it. And with the image data,
The graphic data storage means for storing the graphic data displayed on the display means, and the graphic data to be displayed on the display means from the graphic data stored in the graphic data storage means to select the enlarged / reduced image data. A data synthesizing unit that is two-dimensionally developed in the storage unit and synthesizes with the temporarily stored image data, and the image data and the graphic data synthesized by the data synthesizing unit are two-dimensionally developed, The combined data storage means for storing, the data area selection means for selecting a part of the data area stored in the combined data storage means, and the part of the data area selected by the data area selection means are two-dimensionally And a window memory means for temporarily storing the data, and two-dimensionally stored data temporarily stored in the window memory means on the display means as an image. It is achieved by an image forming apparatus and an image display means for displaying.

In a preferred embodiment of the present invention,
Image data is generated using a stimulable phosphor sheet.
ing. In a further preferred embodiment of the present invention,
The image data is autoradiographic image data,
Radiation diffraction image data, electron microscope image data and conversion
Image data selected from the group consisting of academic luminescence image data
It is composed of Further preferred embodiment of the present invention
In, the radiographic image data, radiation
Is the diffraction image data or electron microscope image data a sample?
The radiation or electron beam emitted from the phosphor is stored in the stimulable phosphor.
The stimulable phosphor is then subjected to an electromagnetic wave.
The light emitted from the stimulable phosphor is photoelectrically irradiated by irradiating waves.
It is obtained by converting. Further preferred of the present invention
In a preferred embodiment, the chemiluminescence image is emitted from the sample.
The stimulable phosphor accumulates and absorbs visible light.
After that, the photostimulable phosphor is irradiated with an electromagnetic wave,
By photoelectrically converting the light emitted from the stimulable phosphor,
Has been obtained. In the present invention, an autoradiograph
Image, radiation diffraction image or electron microscope image
As a stimulable phosphor that can be used for
It can store radiation or electron beam energy, and
Of accumulated radiation or electron beams that are excited by
Anything that can release energy in the form of light,
However, it is not limited to light in the visible wavelength range.
Those that can be excited are preferred. Specifically,
For example, the algorithm disclosed in JP-A-55-12145 is disclosed.
Potassium earth metal fluoride halide phosphor (Ba_1-x,M²⁺
_x) FX: yA (here, M²⁺Is Mg, Ca, Sr, Z
at least one selected from the group consisting of n and Cd
Alkaline earth metal element, X is Cl, Br and I
At least one halogen selected from the group
u, Tb, Ce, Tm, Dy, Pr, Ho, Nd, Yb
And at least one 3 selected from the group consisting of
Valent metal element, x is 0 ≦ x ≦ 0.6, y is 0 ≦ y ≦ 0.2
Is. ), Disclosed in JP-A-2-276997.
Alkaline Earth Metal Fluoride Halide Phosphor SrF
X: Z (where X is a group consisting of Cl, Br and I
At least one halogen selected, Z is Eu or
It is Ce. ), Disclosed in JP-A-59-56479.
Europium-activated composite halogen-based phosphor BaF
X.xNaX ': aEu²⁺(Where X and X'yes
The deviation is also a small amount selected from the group consisting of Cl, Br and I.
At least one kind of halogen, x is 0 <x ≦ 2, and a is
0 <a ≦ 0.2. ), JP-A-58-69281
Cerium-activated trivalent metal oxyhalogen disclosed in the publication
MOX: xCe (where M is Pr,
Nd, Pm, Sm, Eu, Tb, Dy, Ho, Er, T
at least selected from the group consisting of m, Yb and Bi
A trivalent metal element, X is one of Br and I.
Or both, x is 0 <x <0.1. ), JP Sho
60-101179 and 60-90288.
Cerium-activated rare earth oxyhalogen compounds disclosed in the publication
-Based phosphor LnOX: xCe (where Ln is Y,
At least one selected from the group consisting of La, Gd and Lu
Is also a kind of rare earth element, X is Cl, Br and I
At least one halogen selected from the group, x is 0 <
x ≦ 0.1. ) And JP-A-59-75200
Europium-activated composite halogen-based firefly disclosed in the publication
Light body M^IIFX aM^IX'bM^'IIX^'' ₂・ CM^III
X^''' ₃・ XA: yEu²⁺(Here, M^IIIs Ba, Sr
And at least one a selected from the group consisting of
Lucari earth metal element, M^IIs Li, Na, K, Rb and
And at least one alka selected from the group consisting of Cs
Remetal element, M '^IIIs selected from the group consisting of Be and Mg
At least one divalent metal element, M^IIIIs Al,
At least one selected from the group consisting of Ga, In and Tl
Is also a trivalent metal element, A is at least one metal oxide
And X is a small amount selected from the group consisting of Cl, Br and I.
At least one kind of halogen, X ', X^''And X^'''Is
Less selected from the group consisting of F, Cl, Br and I
Both are a kind of halogen, a is 0 ≦ a ≦ 2, and b is
0 ≦ b ≦ 10^-2, C is 0 ≦ c ≦ 10^-2And, a +
b + c ≧ 10^-2And x is 0 <x ≦ 0.5, and y
Is 0 <y ≦ 0.2. ) Is preferably used
It

In the present invention, stimulable phosphors that can be used to generate a chemiluminescent image include:
Any energy capable of accumulating light energy in the visible light wavelength range, being excited by electromagnetic waves, and capable of releasing accumulated energy of light in the visible light wavelength area in the form of light, is not particularly limited. However, those that can be excited by light in the visible light wavelength range are preferable. Specifically, for example, the metal halophosphate-based phosphor, the rare earth element-activated phosphor, the aluminate-based phosphor, the silicate-based phosphor, and the fluoride-based phosphor disclosed in JP-A-4-232864 are disclosed. Body is,
It can be preferably used.

[0011]

According to the present invention, the image data corresponding to the image data within the range of the image data which is two-dimensionally expanded and temporarily stored in the composite data storage means is a display means such as a CRT screen. If you want to scroll the image displayed in, use the data area selection means, in the window memory,
An image displayed on a CRT or the like can be scrolled by selecting data that is two-dimensionally expanded and temporarily stored, and therefore, an image displayed on the CRT or the like can be scrolled at high speed. It will be possible.

[0012]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT A preferred embodiment of the present invention will be described in detail below with reference to the accompanying drawings. Figure 1
FIG. 1 is a schematic perspective view showing an example of an image reading apparatus that generates image data for an autoradiographic image forming apparatus according to an exemplary embodiment of the present invention. In FIG. 1, positional information of a radioactive labeling substance contained in a sample (not shown) is accumulated in a stimulable phosphor sheet 1 in the form of radiation energy. In this example, positional information of the radiolabeled substance in the gene using the Southern blotting method and the hybridization method is accumulated and recorded in the stimulable phosphor sheet 1. Here, the positional information is various information centered on the position of the radiolabeled substance or its aggregate in the sample, for example, the existence position and shape of the aggregate of the radiolabeled substance present in the sample, and its position. It means various information obtained as one or any combination of information including the concentration and distribution of the radiolabeled substance.

The position information of the radiolabeled substance in the sample is stored and recorded in the stimulable phosphor sheet 1 as follows, for example. That is, first, a plurality of DNA fragments including a DNA fragment consisting of a target gene are separated and developed by performing electrophoresis on a gel support medium, and denatured by alkali treatment (denaturation) to obtain single-stranded DNA. Of DNA. Then, the gel support medium and a transfer support such as a nitrocellulose filter are superposed by a known Southern blotting method, and at least a part of the denatured DNA fragment is transferred onto the transfer support, followed by heating treatment. , Fix it. Then, the probe prepared by a method such as radiolabeling DNA or RNA complementary to the DNA of the target gene and the denatured DNA fragment on the transcription support are hybridized by a heating treatment to give a double-stranded DNA. Re-naturation of DNA or formation of DNA / RNA conjugates. At this time, since the denatured DNA fragment on the transcription support is fixed, only the DNA fragment complementary to the probe DNA or the probe RNA hybridizes to capture the radiolabeled probe. Then, by washing away the probe that did not form a hybrid with an appropriate solution, only the DNA fragment having the gene of interest forms a hybrid with the radiolabeled DNA or RNA on the transcription support, A radioactive label is attached. In this way, the transfer support thus obtained and the stimulable phosphor sheet 1 are overlapped for a certain period of time, and an exposure operation is performed, whereby at least a part of the radiation emitted from the radiolabeled substance on the transfer support is The position information of the radiolabeled substance in the sample absorbed by the stimulable phosphor sheet 1 is stored in the stimulable phosphor sheet 1.
It is stored and recorded in.

The stimulable phosphor sheet 1 on which the positional information of the radiolabeled substance in the sample is accumulated and recorded is scanned with the laser beam 2 to be excited to generate stimulated emission. The laser light 2 is generated by the laser light source 3, and the filter 4
By passing through, the portion of the wavelength region corresponding to the wavelength region of the photostimulable light generated from the stimulable phosphor sheet 1 due to the excitation by the laser light 2 is cut. Then, the beam diameter of the laser beam 2 is accurately adjusted by the beam expander 5, and the laser beam 2 enters the optical deflector 6 such as a galvanometer mirror. Laser light 2 deflected by the optical deflector 6
Is reflected by the plane reflecting mirror 8 via the fθ lens 7 and is one-dimensionally incident on the stimulable phosphor sheet 1.
The fθ lens 7 ensures that when the stimulable phosphor sheet 1 is scanned by the laser light 2, the scanning is always performed at a uniform beam speed. In synchronization with the scanning with the laser light 2, the stimulable phosphor sheet 1 is moved in the direction of arrow A in FIG. 1, and the entire surface thereof is scanned with the laser light 2. When the stimulable phosphor sheet 1 is irradiated with the laser beam 2, the stimulable phosphor sheet 1 emits photostimulable light in an amount proportional to the radiation energy stored and recorded, and the emitted photostimulable light is incident on the light guide sheet 9. To do.

The light-guiding sheet 9 has a light-receiving end portion formed in a straight line shape and is arranged in proximity to the scanning line on the stimulable phosphor sheet 1, and the light-exiting end portion thereof has a circular shape. It forms an annular shape and is connected to the light receiving surface of a photoelectric conversion type photodetector 10 such as a photomultiplier. This light guide sheet 9 is made by processing a transparent thermoplastic resin sheet such as an acrylic synthetic resin, and the light incident from the light receiving end repeats total reflection on the inner surface of the light emitting sheet while the light exiting end is emitted. The shape is determined so as to be transmitted to the light receiving surface of the photodetector 10 through the portion. Therefore, the photostimulable light emitted from the stimulable phosphor sheet 1 in response to the irradiation of the laser beam 2 is incident on the light guide sheet 9, and inside the light guide sheet 9, while repeating total reflection, through the emission end portion, The light is received by the photodetector 10. A filter is attached to the light-receiving surface of the photodetector 10, which transmits only the light in the wavelength region of the photostimulable light emitted from the stimulable phosphor sheet 1 and cuts the light in the wavelength region of the laser light 2. Therefore, the photodetector 10 is configured to photoelectrically detect only stimulated light emitted from the stimulable phosphor sheet 1. The photostimulable light photoelectrically detected by the photodetector 10 is converted into an electric signal, amplified by an amplifier 11 having a predetermined amplification factor into an electric signal of a predetermined level, and then the A / D converter 12 Entered in. The electric signal is converted into a digital signal by the A / D converter 12 with a scale factor suitable for the signal fluctuation width, and input to the line buffer 13. The line buffer 13 is
The image data for one scanning line is temporarily stored, and when the image data for one scanning line is stored as described above, the data is stored more than the capacity of the line buffer 13. The image data is output to the transmission buffer 14 having a large capacity, and the transmission buffer 14 is configured to output the image data to the autoradiography image forming apparatus when the image data having a predetermined capacity is stored.

FIG. 2 is a block diagram of an autoradiographic image forming apparatus and an image reading apparatus according to an embodiment of the present invention. In FIG. 2, the autoradiographic image forming apparatus 30 includes a stimulable phosphor sheet 1
The image data containing the position information of the radiolabeled substance contained in the sample, which has been stored and recorded in the image reading device 20 and converted into a digital signal, is received,
In order to reproduce a visible image having proper color tone, contrast, etc. and excellent observation and analysis characteristics, the signal processing means 60 for performing signal processing and the signal processing means 60 input from the image reading device 20 to perform signal processing. The image data storage means 40 for storing the image data thus obtained and the CRT 50 for reproducing the image data including the positional information of the radiolabeled substance contained in the sample as an image are provided. The image data temporarily stored in the transmission buffer 14 of the image reading device 20 is input to the reception buffer 62 of the signal processing means 60 of the autoradiography image forming device 30, is temporarily stored, and is received. When a predetermined amount of image data is stored therein, the stored image data is output to and stored in the image data temporary storage unit 41 of the image data storage means 40. In this way, the image data sent from the transmission buffer 14 of the image reading device 20 to the reception buffer 62 of the signal processing unit 60 and temporarily stored is further stored in the image data storage unit 40 from the reception buffer 62. It is stored in the image data temporary storage unit 41. In this way, when the image data obtained by scanning the entire surface of the stimulable phosphor sheet 1 with the laser light 2 is stored in the image data temporary storage unit 41 of the image data storage unit 40, the signal of the signal processing unit 60 is output. The processing unit 64 includes the image data temporary storage unit 41.
The image data is read from the image processing unit 60, stored in the temporary memory 66 of the signal processing unit 60, subjected to necessary signal processing, and then only such image data is stored in the image data storage unit 42 of the image data storage unit 40. After that, the image data stored in the image data temporary storage unit 41 is deleted.

The image data stored in the image data storage unit 42 of the image data storage unit 40 is read out by the signal processing unit 64 and displayed on the screen of the CRT 50 for the operator to observe and analyze the image. It is supposed to be displayed. FIG. 3 is a block diagram of the signal processing means 60. In FIG. 3, a signal processing unit 60 includes a reception buffer 62 that receives image data from the transmission buffer 14 of the image reading device 20, a signal processing unit 64 that executes signal processing, and a temporary memory that temporarily stores image data. Equipped with 66. The temporary memory 66 stores the image data,
It is configured to be two-dimensionally developed and temporarily stored. The signal processing means 60 further includes a temporary memory 66.
The image data selecting unit 68 for selecting a part of the image data from the image data temporarily stored in the image data, and the image data enlarging / reducing unit for enlarging or reducing the image data selected by the image data selecting unit 68. 70, an image data enlarged / reduced by the image data enlarging / reducing unit 70, and an enlarged / reduced image data storage unit 72 for two-dimensionally expanding and temporarily storing the image data, and displaying it on the screen of the CRT 50. Figure data storage unit 7 for storing various kinds of figure data
4, the image data temporarily stored in the enlarged / reduced image data storage unit 72 and the graphic data stored in the graphic data storage unit 74 and to be displayed on the screen of the CRT 50. A composite image data storage unit 77 that two-dimensionally expands the image data and the graphic data synthesized by the data synthesizing unit 76 and temporarily stores them.
A data area selecting section 78 for selecting a predetermined data area from the image data and the graphic data temporarily stored in the composite image data storage section 77; and the image data selected by the data area selecting section 78. The data area of the graphic data is two-dimensionally developed and temporarily stored, and the image data that is two-dimensionally developed in the window memory 79 and temporarily stored is two-dimensionally stored. And a monitor frame position setting unit 8 for setting a position for generating a monitor frame in the window memory 79.
2, a monitor frame position calculation unit 84 that calculates the position of the monitor frame in the window memory 79, a monitor frame position storage unit 86 that stores the position of the monitor frame calculated by the monitor frame position calculation unit 84, and a monitor frame. The generation unit 80 selects a profile generation unit 88 that generates profile data corresponding to the gradation of the image of the image data surrounded by the monitor frame generated in the window memory 79, and the data area selection unit 77. The area of the image data and graphic data temporarily stored in the memory 79, the monitor frame position data stored in the monitor frame position storage unit 86, and the profile data generated by the profile generation unit 88 are displayed on the CRT.
The image display unit 90 displayed on the screen of 50 and the profile image corresponding to the profile data of the image data generated by the profile generation unit 88 are specified by the monitor frame generation unit 80 in the window memory 79, and the image is displayed. The display unit 90 includes an image gradation adjusting unit 92 that adjusts the gradation in a specific area of the image displayed on the screen of the CRT 50.

The image data selection unit 68 receives the image data selection signal from the selected image data determination unit 100, and the image data enlargement / reduction unit 70 receives the enlargement / reduction signal from the image data magnification determination unit 102. It has been entered. Further, a graphic data selection signal from the graphic data selecting means 104 is input to the graphic data storage unit 74, and which graphic data is selected in the data synthesizing unit 76 and how the image data and the graphic data are synthesized. Then, the data synthesizing instructing means 10 for deciding whether to display on the screen of the CRT 50.
The data synthesis signal from 6 is input. Further, the data area selection unit 78 receives a data area designation signal from the data area designation means 107. A monitor frame display instruction signal from the monitor frame display instruction unit 108 is input to the monitor frame generation unit 80 and the monitor frame position setting unit 82, and the profile generation unit 88
A profile data generation signal from the profile generation instruction means 110 is input. In addition, the image display unit 90
An image display instruction signal from the image display instruction unit 112 is input to the image gradation instruction unit 112, and a gradation adjustment instruction signal from the image gradation adjustment instruction unit 114 is input to the image gradation adjustment unit 92. Here, in the present embodiment, the selected image data determination means 100, the image data magnification determination means 102, the graphic data selection means 104, the data combination instruction means 106, the data area designation means 107, the monitor frame display instruction means 108,
Profile generation instruction means 110, image display instruction means 1
12 and the image gradation adjustment instructing means 114 are operable by a mouse (not shown).

FIG. 4 shows the CRT 50 which stores the image data which is two-dimensionally expanded and temporarily stored in the temporary memory 66.
3 shows an example of an image when displayed on the screen of FIG. 1, and the entire image data is two-dimensionally developed and stored in the temporary memory 66. In FIG. 5, the operator operates the selected image data determining means 100 to select a part of the image data stored in the temporary memory 66, and operates the image data magnification determining means 102 to select the selected image. An example of an image in which the data is enlarged at a predetermined magnification, two-dimensionally expanded in the enlarged / reduced image data storage unit 72, and the temporarily stored image data is displayed on the screen of the CRT 50 is shown. It is a thing. As shown in FIG. 5, in the enlarged / reduced image data storage unit 72, a part of the image data that is two-dimensionally expanded and temporarily stored in the temporary memory 66 is enlarged and stored in the temporary memory 66. It is dimensionally expanded and stored. In FIG. 6, the graphic data selecting means 104 and the data synthesizing instructing means 106 are further operated to two-dimensionally expand the image data in the enlarged / reduced image data storage unit 72, and the image data temporarily stored. Image data that has been synthesized and is two-dimensionally developed in the synthesized data storage unit 77, and the temporarily stored image data is CR.
It is an example of an image when displayed on the screen of T50. As shown in FIG. 6, the combined data storage unit 77
In the enlarged / reduced image data storage unit 72, the image data that is two-dimensionally expanded and temporarily stored is combined with predetermined graphic data, and the two-dimensionally expanded image data is temporarily expanded. Remembered

FIG. 7 further shows that the CRT 50 displays the image data which is two-dimensionally expanded and temporarily stored in the window memory 79 when the monitor frame display instructing means 108 is operated to generate the monitor frame. An example of an image when displayed on the screen is shown. As shown in FIG. 7, in the window unit 120 of the window memory 79, a part of the image data consisting of the image data and the graphic data which are two-dimensionally expanded and temporarily stored in the composite image data storage unit 77. The image data 122 is stored together with the monitor frame 128 generated by the monitor frame generation unit 80, and the profile display unit 124 for displaying the profile data is stored in the remaining portion.
In this state, when the operator operates the image display instruction means 112 with a mouse (not shown) to input an image display instruction signal to the image display section 90, the screen of the CRT 50 is completely different from that shown in FIG. The same image is displayed. In the autoradiographic image forming apparatus configured as described above,
It is necessary to enlarge or reduce the image displayed on the screen of the CRT 50 or to scroll the image according to the portion of the image to be observed and analyzed.

CR depending on the part of the image to be observed and analyzed
In order to enable enlargement or reduction of the image displayed on the screen of T50, in this embodiment, the operator operates the image data magnification determination means 102 with the mouse to enlarge the image data. By inputting the enlargement / reduction signal to the reduction / reduction unit 70, the enlarged / reduced image data storage unit 72 can two-dimensionally expand the enlarged or reduced image data and temporarily store it. You can do it. Further, the operator operates the selected image data determination means 100 using the mouse to move the image data selection unit 6
By inputting the image data selection signal to 8,
The image displayed on the screen of the RT 50 can be scrolled. In this case, the image data designated by the selected image data determination means 100 is selected from the temporary memory 66 by the image data selection unit 68, and the image data enlargement / reduction unit 70 enlarges or reduces the image data. Alternatively, the image data is not expanded or reduced, but is expanded two-dimensionally and temporarily stored in the expanded / reduced image data storage unit 72, and further, the data combining unit 76 combines predetermined graphic data. Then, it is two-dimensionally expanded and temporarily stored in the composite image data storage unit 77, and then the data area selection unit 78 selects the image data and graphic data areas stored in the composite image data storage unit 77. The image is displayed in the window memory 79 after being two-dimensionally expanded and temporarily stored. For the first time by 0, CR
The image on the screen of T50 is scrolled.
However, with such an operation, it is difficult to scroll the image on the screen of the CRT 50 at high speed. Therefore, in the present embodiment, the composite image data storage unit 77
A data selection unit 78 is provided which can select an area of data consisting of image data and graphic data stored in the window memory 79 and can be two-dimensionally developed in the window memory 79 and temporarily stored. Therefore, the operator inputs the data area designating signal to the data area designating means 107 by using the mouse, whereby the window memory 7
The area of the image data and the graphic data which is two-dimensionally expanded and temporarily stored in 9 can be designated, and within the range of the data including the image data and the graphic data stored in the composite image data storage unit 77. Then, the image on the screen of the CRT 50 can be scrolled at high speed.

The image data selection unit 68 causes the CRT 5
Whether the image on the screen of 0 is scrolled or the image on the screen of the CRT 50 is scrolled by the data selection unit 78 is determined by the first button (not shown) or the second button (not shown) provided on the mouse. It is selectable by operating (not shown). As described above, the operator scrolls the image displayed on the screen of the CRT 50 according to the image area to be observed and analyzed, after enlarging or reducing the image, or without enlarging or reducing the image. By storing the image region to be observed and analyzed in the monitor frame 128 and operating the profile generation instruction means 110 using a mouse (not shown) to input the profile data generation signal to the profile generation unit 88, C
The gradation profile of the image area surrounded by the monitor frame 128 on the screen of the RT50 is displayed in the profile display unit 12
4, and can be observed and analyzed. As a result, when it is determined that the gradation profile of the image area in the monitor frame 128 should be adjusted so as to be more suitable for the observation analysis, the operator uses the mouse to operate the image gradation adjustment instruction means 114. By operating and inputting a gradation adjustment instruction signal to the image gradation adjusting section 92, the gradation profile of the image area specified by the monitor frame 128 can be adjusted.

The present invention is not limited to the above embodiments, and various modifications can be made within the scope of the invention described in the claims, and these are also included in the scope of the present invention. It goes without saying that it is a thing. For example, in the above-mentioned embodiment, the positional information of the gene using the hybridization method by Southern blotting method is accumulated and recorded in the stimulable phosphor sheet 1, and this is photoelectrically read to perform a predetermined signal processing. The case where the gradation profile of the image region to be observed and analyzed is adjusted by displaying the image on the screen of the CRT 50 is described, but the present invention is not limited to such autoradiography. Thin layer chromatography (TL
C) autoradiographic image, polyacrylamide gel electrophoresis method for autoradiographic image for protein separation, identification, or evaluation of molecular weight and properties, metabolism of administered substance in experimental mice, Chemoluminescence images of genes using the Southern blot hybridization method, as well as other autoradiographic images such as those for studying absorption and excretion pathways and conditions.
Chemiluminescence images such as chemiluminescence images generated by thin-layer chromatography of proteins, chemiluminescence images for separation and identification of proteins, and evaluation of molecular weight and characteristics by polyacrylamide gel electrophoresis were used. Chemiluminescence images, electron beam transmission images and electron beam diffraction images of metal or non-metal samples generated using an electron microscope, electron microscope images of biological tissues, and radiation diffraction of metal or non-metal samples. It can be widely applied to images and the like.

Further, in the above embodiment, the CRT 50
The image displayed on the screen is enlarged or reduced, and further scrolled to fit the image area to be observed and analyzed into the monitor frame 128, and the gradation of the image area is adjusted. The image displayed on the screen is enlarged or reduced, scrolled, and the position of the monitor frame 128 is moved so that the image region to be observed and analyzed is accommodated in the monitor frame 128 and the gradation of the image region is adjusted. May be adjusted. Further, in the above-described embodiment, the monitor frame 128 specifies the image area to be observed and analyzed, and the gradation profile of the image in that area is obtained. The graphic data corresponding to the graphic is stored in a predetermined position in the composite image data storage unit 77, and the CRT 50
It is also possible to display the image on the screen, specify the image area to be observed and analyzed on the screen of the CRT 50 by this figure, specify it, and obtain the gradation profile of the image in the image area. In addition, in the above-described embodiment, the image data obtained by converting the positional information of the radiolabeled substance in the sample into an electric signal using the stimulable phosphor sheet 1 is used as the CRT50.
Although it is displayed on the screen as a visible image, a photographic film is used instead of the stimulable phosphor sheet 1.
It is also possible to form a visible image, photoelectrically read the visible image, and perform similar processing on the image data converted into an electric signal.

Further, in the present invention, the term "means" does not necessarily mean physical means, but also includes the case where the function of each means is realized by software.
Further, the function of one means may be realized by two or more physical means, or the functions of two or more means may be realized by one physical means.

[0026]

According to the present invention, based on image data,
It is possible to provide an image forming apparatus that forms a visible image on a CRT screen and is capable of scrolling an image reproduced on a display unit such as a CRT screen at high speed.

[Brief description of drawings]

FIG. 1 is a schematic perspective view showing an example of an image reading apparatus for generating image data for an autoradiographic image forming apparatus according to an embodiment of the present invention.

FIG. 2 is a block diagram of an autoradiographic image forming apparatus and an image reading apparatus according to an embodiment of the present invention.

FIG. 3 is a block diagram of a signal processing means.

FIG. 4 is a drawing showing image data two-dimensionally developed and stored in a temporary memory.

FIG. 5 is a drawing showing image data that is two-dimensionally expanded and stored in an enlarged / reduced image data storage unit.

FIG. 6 is a drawing showing image data that is two-dimensionally developed and stored in a composite image storage unit.

FIG. 7 is a drawing showing image data that is two-dimensionally expanded and stored in a window memory.

[Explanation of symbols]

 1 Storage Phosphor Sheet 2 Laser Light 3 Laser Light Source 4 Filter 5 Beam Expander 6 Optical Deflector 7 fθ Lens 8 Planar Reflector 9 Light Guide Sheet 10 Photodetector 11 Amplifier 12 A / D Converter 13 Line Buffer 14 transmission buffer 20 image reading device 30 autoradiography image forming device 40 image data storage unit 41 image data temporary storage unit 42 image data storage unit 50 CRT 60 signal processing unit 62 reception buffer 64 signal processing unit 66 temporary memory 68 image data selection 70 Image data enlargement / reduction unit 72 Enlarged / reduced image data storage unit 74 Graphic data storage unit 76 Data composition unit 77 Data area selection unit 78 Composite image data storage unit 79 Window memory 80 Monitor frame generation unit 82 Monitor frame position setting unit 84 Monitor position Calculation unit 86 Monitor frame position storage unit 88 Profile generation unit 90 Image display unit 92 Image gradation adjustment unit 100 Selected image data determination unit 102 Image data magnification determination unit 104 Graphic data selection unit 106 Data combination instruction unit 107 Data area designation unit 108 Monitor frame display instructing means 110 Profile generation instructing means 112 Image display instructing means 114 Image gradation adjusting instructing means 120 Window section 122 Image data 124 Profile display section 128 Monitor frame

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁶ Identification code Internal reference number FI Technical display location G06T 3/40 G06F 15/66 355 A 450

Claims (5)

[Claims] 1. An image data storage unit for storing image data, and image data stored in the image data storage unit,
Temporary memory means for two-dimensionally expanding and temporarily storing, and image data selection for selecting image data from the image data two-dimensionally expanded and temporarily stored in the temporary memory means. Means, image data enlarging / reducing means for enlarging or reducing the image data selected by the image data selecting means, and two-dimensionally expanding the image data enlarged or reduced by the image data enlarging / reducing means. Then, the enlarged / reduced image data storage means for temporarily storing, the graphic data storage means for storing the graphic data displayed on the display means together with the image data, and the graphic data stored in the graphic data storage means. From among the image data to be displayed on the display means, and the image data stored in the enlarged / reduced image data storage means two-dimensionally and temporarily stored. Of the data area stored in the combined data storage means, the combined data storage means for two-dimensionally developing and storing the image data and the graphic data combined by the data combiner. Data area selecting means for selecting a part, and a window memory means for two-dimensionally expanding a part of the data area selected by the data area selecting means and temporarily storing the data area,
An image forming apparatus, comprising: an image display unit for displaying, as an image, data that is two-dimensionally expanded in the window memory unit and temporarily stored on the display unit. 2. The image forming apparatus according to claim 1, wherein the image data is generated by using a stimulable phosphor sheet. 3. The image data is composed of image data selected from the group consisting of autoradiography image data, radiation diffraction image data, electron microscope image data, and chemiluminescence image data. Alternatively, the image forming apparatus described in 2. 4. The autoradiographic image data,
The radiation diffraction image data or the electron microscope image data, the radiation or electron beam emitted from the sample, accumulated in the stimulable phosphor, to absorb, after which, the stimulable phosphor, by irradiating an electromagnetic wave. The image forming apparatus according to claim 3, wherein the image forming apparatus is generated by photoelectrically converting light emitted from the stimulable phosphor. 5. The chemiluminescent image allows visible light emitted from a sample to be accumulated and absorbed in a stimulable phosphor, and thereafter, the stimulable phosphor is irradiated with an electromagnetic wave to produce the stimulable phosphor. The image forming apparatus according to claim 3, wherein the image forming apparatus is generated by photoelectrically converting light emitted from the luminescent phosphor.