JPH09202A - Food for stress - Google Patents

Abstract

(57) [Summary] [Objective] An object of the present invention is to provide a food composition that reduces the invasion due to the health-inhibiting factors that increase with the modernization of life by activating the resistance to stress. [Structure] The main function of spirulina was to ensure that the functionality of spirulina is expressed more reliably by incorporating multiple herbal medicines.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a food product for stress prepared by mixing a plurality of aspirative crude drugs with spirulina.

[0002]

2. Description of the Related Art The modernization of life inevitably produces various health-impairing factors as a by-product at the cost of convenience and comfort. Air pollutants associated with energy consumption, pesticides associated with increased food production, fungicides and insecticides whose use expands in proportion to environmental beautification,
There is no stopping the increase in factors that impair health around people's lives, such as ozone depleting substances that are gradually increasing ultraviolet rays and stress accumulated due to overcrowding of personal relationships.

The damage caused by these health-inhibiting factors is certainly weighted by any person, but since the progress is slow, it is easy to miss the time of coping, and the mischievous subjective symptoms are rarely manifested. Absent. At that time, treatment with drugs has already been unavoidable, and side effects such as continuous use of drugs will cause new demand for great costs.

The health-inhibiting factor described above acts as a stress that secondarily imbalances the immune system of all the bodies, but it is recently being actively used to prevent it. In the functional search of food objects, it is difficult to avoid uncertainty in effect reproduction due to the complexity of interactions among ingredients in general foods, and in particular, there is no food that can reduce body damage in response to stress.

[0005]

The present invention is one of the most useful nutritional components in terms of type, amount, and balance, but the reproducibility of the health maintenance function is unsatisfactory for humans. By mixing multiple spirulina herbs with Spirulina, mental and physical problems that are a byproduct of modernization of life,
In particular, it aims to provide foods that can effectively prevent the decline in body normalizing ability due to stress accumulation.

[0006]

[Means for Solving the Problems] Spirulina, which the present inventor has continued to study for a long time, has a long history of eating as a food for maintaining health, but the effect of the effect varies greatly from person to person. Even if you start taking it with the intention of maintaining it,
The interruption often ends the effort to strengthen the health infrastructure in vain. Needless to say, this is common in foods used for the purpose of maintaining health, but there is a strong expectation that the financial health insurance will collapse in addition to environmental deterioration, and nowadays there is a strong demand for primary health care, and it is the most nutritious. As a matter of urgent need to increase the functional expression rate of Spirulina, which has a good balance, we have mixed various ingredients into Spirulina and conducted trial and error. They have found that the reproducibility of the maintenance function can be improved, and have completed the present invention.

[0007] The present invention further provides a food containing spirulina as a set of carrot herbs such as ginseng, licorice and reishi.

[0008]

[Detailed Description] First, the spirulina referred to in the present invention is an alga derived from bacteria in the genus Spirulina of the genus Spirulina of the genus Cyanophyta. Maxima (Spirulina)
Most preferred is the use of maxima).

Further, the replenishing herbal medicine as referred to in the present invention is a herbal medicine that has been used in Chinese medicine (Chinese traditional medicine) and has both warmness and sweetness (heat retention and nourishment).
anax ginseng), Astragalus (Asutraga)
lasmembranaceus), Party Participants (Codon
opsis pilosula), mountain herb (Diosco)
rea batatas), Shiroyaku (Atractylo)
des batataS), Ojumu (Zyiffus)
Jujuba), licorice (Glycyrrhiza ur)
alensis), candy candy (Saccharum gra)
norum), Shikawa (Placenta homin)
is), Reishi (Ganoderma japonicu)
m), Eucommia ulmoides,
Walnut meat (Juglans regia), Cordyceps (C)
ordyceps sinensis).
Classification of "Clinical application of Chinese medicine ... Kobe Chinese Medicine Study Group, translation / edition, published by Ito Denryaku Publishing Co., Ltd." The use form of these crude drugs does not impair the effects of the present invention, either as a bulk powder or an extract, as in common Chinese herbs.

[0010] First of all, the improvement of complaints by continuous ingestion of spirulina alone by several studies showed a sex difference such as blood nutritional effects in men and a sweating function balance in women, and the improvement rate was more than half. It does not exceed.
Of course, since it is taken for the purpose of maintaining good health, the subjective symptom improvement rate should not be the only criterion, but in order to improve primary health care, health-inhibiting factors in daily life, especially tolerance to stress Good at,
Moreover, the issue is how to direct things that do not differ in their appearance.

From the above, the present inventor can more certainly induce the nutritional and function-based effects of spirulina, which should be extremely useful for maintaining health, in view of the mechanism that enhances photosynthesis most and the content of ingredients. Searching for ingredients was empirically and analytically requested for crude drugs with safety data, and repeated screening of function-inducing ability by adding single or multiple of them to Spirulina, and addition to Spirulina was extremely stressed. We have found a combination of crude drugs that prevent accumulation damage and that can be reproduced at a high rate without sex difference. That is, this is the one in which a plurality of aspirating crude drugs are arranged in spirulina as a food for stress according to the present invention.

[0012] As mentioned above, there are enumeration of health-inhibiting factors that increase with modernization of life, but they can be summarized by exerting stress and weakening the health maintenance function. However, the coping method is only to avoid stress and to have a balanced diet, and to recommend vitamins and calcium. Here, the present inventor first focused on interferon γ (IFNγ) whose productivity decreases in proportion to the degree of stress accumulation in the living body, and in the saucer of healthy human IFNγ production and its effect expression by ingesting the food composition of the present invention. There is 2
-5A synthase activation is measured to check resistance to stress,
Next, in the atopic constitution, since the onset of dermatitis is likely to be triggered by stress, the transition of serum immunoglobulin E (IgE) and dermatitis due to the ingestion of the food composition of the present invention is observed to improve the stress tolerance. I considered.

In the food composition of the present invention, the amount of spirulina as a main raw material is 30 to 95% by weight as a dry powder.
Is suitable, and the amount of each herbal medicine to be distributed is 0.3 to 3% by weight as an extract. Extraction of these crude drug extracts may be carried out by any known method using water or lower aliphatic alcohols or hydrous lower aliphatic alcohols, and, in the entire composition, can be generally used for foods. The addition of the raw materials used does not affect the effect of the present invention.

[0014]

[Examples] As spirulina, use is made of a powder which is cultivated in a batch method in an alkaline state of salt water and dried by a known method such as spray drying. 1 kg of dried carrot shreds, among the herbal medicines
Is extracted with 5 l of 30% ethanol for 3 hours, and this operation is repeated twice to combine the extracts. The filtrate after cooling is concentrated under reduced pressure to 200 g to make a soft extract. licorice,
An extract is obtained in the same manner for Reishi.

Using each of the above raw materials, the following formulation 1
Make an elementary grain of 0.2g. Amount of each raw material in 100 g of grain (number is% by weight) Spirulina 70.0 Carrot extract 0.5 Licorice extract 1.0 Reishi extract 0.5 Refined soybean oil (binder) 3.0 Dry potato starch (dispersion) Remaining amount

[0016]

[Test Example 1] 10 healthy volunteers (41 to 61 years old, 5 males and 5 females) were continuously ingested with 30 granules a day for 4 weeks, and the same as before, 2 weeks after the start of ingestion. 4 weeks later, IFNγ production in blood and 2-5
A transition of the activity of A (2'5 'oligoadenylic acid) synthase was observed. The results are shown in Tables 1 and 2.

IFNγ production was carried out using human amniotic cells and Sindbis virus (Sindobis virus) 50% CPE for measurement samples prepared from blood samples.
(Cytopathic effect) By bioassay by suppression,
The 2-5A synthase activity was measured 20 hours after Sendai virus stimulation by a radioimmunoassay kit for measuring the enzyme activity.

[0018]

[Test Example 2] 18 volunteers a day for 18 weeks a day for 4 volunteers (8 to 14 years old, 3 females) who have atopic constitution and whose exacerbation of skin inflammation occurs during strong self-inhibition After continuous ingestion, changes in serum IgE value and changes in dermatitis state before and after ingestion were observed. The results are shown in Table 3.

The serum IgE value was measured by the radioimmunoassay (RIA) method. Regarding the skin condition, the subjective symptom of the person was asked about the following 4 stages, and the one that was improved by 2 stages or more before and after ingestion was effective. Those that had stage improvement were considered to be slightly effective. (Skin condition) When irritation is high: 1. The redness is terrible and itching that I can't stand. 2. There is redness, but I can bear the itchiness. 3. Redness is not noticeable and itching is slightly itchy. 4. Not aware of redness and itching.

In the above-mentioned Test Example 1 and Test Example 2, all the general biochemical test values of the blood of each volunteer before and after the test period were normal, and there were no noticeable fluctuations. .

As can be seen from the results of Table 1, Table 2 and Table 3, the composition of the present invention has a high reproducibility and is suitable for IFNγ and 2-5A.
By inducing synthase and suppressing IgE overproduction, the body's resistance to tangible and intangible stress invasion can be improved well.

[0022]

The food composition of the present invention contains spirulina as a main component, but the function expression by ingestion thereof is significantly higher than in the case of ingestion of spirulina alone, and the appearance thereof is
It is clear that it is possible to relieve stress, that is, to reduce stress, for which the treatment method is unclear. All of the constituent raw materials were all edible, and in each test example, no signs of side effects were observed subjectively or by blood tests.

Therefore, in a place of living where modernization is further advanced, fatigue of the health maintenance function, which is overused, can be safely and effectively reduced by ingesting it.

[0024]

[Table 1]

[0025]

[Table 2]

[0026]

[Table 3]

Claims (2)

[Claims] 1. A stress-compatible food comprising spirulina and a plurality of aspirating crude drugs. 2. The stress-responsive food according to claim 1, wherein the plurality of aspirative crude drugs is a set of carrot, licorice, and ganoderma lucidum.