JPH0971520A - Skin cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin cosmetic by using both yeast or its extract and an extract of a specific fruit as a Chinese medicine, preventing dark skin, rapidly lightening dark skin, excellent in chapped skin preventing effect, keratin improving effect, etc. SOLUTION: This skin cosmetic is obtained by combining yeast and/or its extract with an extract of a fruit of Pyracantha fortu-neana, SEKISOU in Chinese, a kind of Pyracantha fortu-neana. The content of the yeast/its extract is about 0.0001-20.0wt.% calculated as a dried solid substance amount. The active ingredient of the fruit of Pyracantha fortu-neana, SEKISOU in Chinese, called SEKIYOUSHI as Chinese medicine name is extracted with water or a lower alcohol such as methanol, its mixed solution. The extracted solution is used as it is but preferably powdered and used. The amount of the fruit is about 0.001-5wt.% calculated as the extract. The cosmetic develops aging preventing effect and skin beautifying effect and can keep skin healthy.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The technical field to which the present invention pertains is
It has the effect of preventing dark skin and quickly lightening dark skin, and also exhibits excellent skin roughening prevention effect, keratin improvement effect, anti-aging effect and beautiful skin effect, and keeps the skin healthy. It is a skin cosmetic that can be applied.

[0002]

2. Description of the Related Art Conventionally, whitening cosmetics for the purpose of preventing or treating skin spots and freckles include L-ascorbic acid and its derivatives,
It contains hydroquinone derivatives, pyrones such as kojic acid, and placental extracts such as placenta extract.

These are widely known as substances having a whitening effect, with the effects of suppressing the production of melanin, light-color bleaching action of the produced melanin, and the like. However, when these substances are used alone, for example, L-ascorbic acid and its derivatives have insufficient storage stability and their effects are not sufficiently exerted, and hydroquinone derivatives have insufficient safety, for example. It was not something.

The Chinese name "Fire thorn" is known as a Chinese medicine name "Red Proton" for its fruit, and it is known to have medicinal effects such as keeping the spleen healthy and treating indigestion. Further, the fruit has a tyrosinase activity inhibitory effect and a melanin production inhibitory effect, and a whitening cosmetic composition containing this extract has been proposed (JP-A-5-58870). However, a sufficient effect was not obtained even when it was blended alone.

Therefore, as a result of intensive studies by the present inventors, a skin cosmetic containing a yeast and / or a yeast extract and a solvent extract of a fruit of the Chinese name "Fire spine" which is one of the genus Pyracanta of the family Rosaceae , Promptly eliminate the melanin present in the epidermis, found that it has an excellent whitening effect, such as suppressing the production of new melanin in the skin, further,
Due to the synergistic action of the components of the yeast extract and the moisturizing components contained in the extract from fire thorns, an excellent effect of preventing rough skin,
The inventors have found that they exhibit a keratin improving effect, an anti-aging effect and a beautiful skin effect, and have completed the present invention.

An object of the present invention is to prevent dark-skinned skin and to quickly lighten the dark-skinned skin, and to exhibit more excellent effects of preventing rough skin, improving keratin, preventing aging and beautiful skin. Another object of the present invention is to provide a skin cosmetic that can keep the skin healthy.

[0007]

Means for Solving the Problems The present invention which achieves the above-mentioned object, comprises a yeast and / or a yeast extract and a solvent extract of a fruit of the Chinese name “Fire thorn” which is a member of the genus Pyracanta of the family Rosaceae. It is a skin cosmetic.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION An embodiment of the present invention is a skin cosmetic.

The structure of the present invention will be described in detail below. The yeast / yeast extract used in the present invention includes yeast itself, dry yeast powder, and appropriate conditions such as autolysis of yeast, hot water extraction, acid hydrolysis, and enzymatic decomposition. There are yeast extracts and the like that have been solubilized, extracted and purified under the conditions below. Beer yeast, baker's yeast, etc. are generally used as yeast Sacc.
There are genus Haromyces and others, and when obtaining a yeast extract, physical, chemical and biochemical methods are applied as the destruction treatment of bacterial cells. In the present invention, it can be arbitrarily selected and used irrespective of a production method such as a bacterial cell species as a raw material, an origin, an extraction method, a purification method, and a treatment method. Above all, commercially available dry powders and yeast extracts of yeast are easy to handle and easily available and convenient. The yeasts and yeast extracts described above contain useful components such as proteins, lipids, inorganic salts, organic acids, vitamins, amino acids, sugars and nucleic acid-related substances.

The content of yeast / yeast extract is 0.00 based on the total amount of prescription ingredients of cosmetics as the dry solid content.
01 to 20.0% by weight is preferable, but not limited to this.

The active ingredient (hereinafter abbreviated as "fire thorn extract") of the Chinese name "red proton" which is a fruit of the Chinese name "fire thorn" used in the present invention is water or methanol, ethanol, propanol and the like. It is extracted with a lower alcohol or a mixed solution thereof. The extract can be blended into cosmetics as it is, but it is preferable to use it by pulverizing it by a freeze-drying method or a spray-drying method. It is also possible to mix the liquid or powdered product by purifying the extract liquid by means of liquid-liquid distribution, adsorption chromatography or the like.

The blending amount is preferably 0.001 to 5% by weight in terms of the extract in the total amount of the cosmetic, but it is not limited to this.

In the cosmetic of the present invention, in addition to the above-mentioned raw materials, pigments, fragrances, preservatives, surfactants, pigments, antioxidants, humectants, ultraviolet absorbers, etc. are achieved to achieve the object of the present invention. It can be appropriately blended within the range.

Examples of the dosage form of the cosmetic of the present invention include cream, emulsion, lotion and pack. For example, in the case of an emulsion or the like, this cosmetic can be produced by an ordinary method of emulsifying and dispersing an oily phase and an aqueous phase, which are dissolved by heating, and cooling.

[0015]

EXAMPLES The present invention will be described in detail below based on examples and comparative examples. The percentages shown in the examples are percentages by weight. The skin color lightness recovery test method described in the examples, the method for measuring the turnover speed of the stratum corneum (the effect of preventing aging), the method for measuring the effect of improving rough skin, and the sensory test (the effect of beautiful skin is as follows).
The method for preparing the fire thorn extract used in the following examples is as follows, but the scope of the present invention is not limited to these.

(Preparation method of fire thorn extract) 5.00 g of dried fire thorn fruit was immersed in 50 ml of hot water at 90 ° C., boiled for 3 hours and then filtered, and the obtained extract was used for Diaion HP-
20 (Mitsubishi Chemical Industries Co., Ltd.) column (φ3 cm × 1)
1 cm, Vt = 80 ml), then 800 ml of 10
% Aqueous solution of ethanol. Then, it was eluted with 400 ml of 40% aqueous ethanol solution, the eluate was concentrated under reduced pressure, and then freeze-dried to obtain 1.04 g of a solid matter.

(1) Skin color lightness recovery test method The back skin of 20 subjects was irradiated with ultraviolet rays in the UV-B region at twice the minimum erythema dose, and a sample application site and a non-application site were set to determine the skin of each skin. The standard brightness (V0 value, V0 'value) was measured. Subsequently, the sample was applied to the application site twice a day for 15 times.
After continuous application for three weeks, the lightness (Vn value, Vn ') of the skin at the application site and the non-application site after 3, 6, 9, 12, and 15 weeks
Was measured, and the recovery of skin color was evaluated according to the following criteria. The lightness of the skin (Munsell color system V value)
Was calculated from the X, Y, and Z values obtained by measuring with a high-speed spectral colorimeter. In addition, the evaluation was shown as an average value of the evaluation points after 3 weeks for 20 subjects.

(2) Measurement of turnover rate of stratum corneum An ointment was prepared by adding 5% by weight of fluorescent dye dansyl chloride to white petrolatum, and applied to the skin of the forearm of a subject.
Apply time-blocking adhesive and osmose dansyl chloride into the stratum corneum. After that, the test sample was applied to the same site twice a day (morning and evening), and the fluorescence of dansyl chloride was examined every day. The number of days until the fluorescence disappeared was defined as the turnover rate of skin keratin. The turnover speed of the normal skin stratum corneum is 14 to 16 days, but it extends around 18 days in aged skin, and decreases to around 12 days when the anti-aging effect appears.

(3) Method for measuring the effect of improving rough skin The effect of continuous application for 4 weeks was investigated on 20 middle-aged and elderly subjects who have rough skin on their lower legs. About 1 g of a sample was applied to the test site of the lower leg of the subject twice a day twice a day, and the skin condition before and after the start of the test was determined according to the following criteria. The lower right leg was not coated with the sample and served as a control. By comparing the judgment results of the test site and the control site before and after the test, when the skin dryness is improved by two or more steps (for example, + →
−, ++ → ±) is defined as “valid”, the case where the signal is improved by one step is “slightly valid”, and the case where there is no change is “invalid”.
The test results are shown by the number of subjects who became “effective” and “slightly effective”.

(4) Sensory test Twenty test subjects evaluated the characteristics of the sample after continuously using the sample for 10 days. The evaluation was shown by the number of respondents who answered "skin became smooth", "a whitening effect was felt", and "tension occurred on the skin" for questionnaire items of smoothness, whitening effect, and elasticity. .

Examples 1 to 3 and Comparative Examples 1 to 3 Yeast extract and fire thorn extract were blended in the composition shown in Table 1, and skin creams were prepared according to the following preparation method. The above test was conducted for each of them, and the results are shown in Table 2.
It was shown to.

[0022]

[Table 1]

[0023]

[Table 2]

Preparation method (A) and (B) are uniformly dissolved at 70 ° C., (A) is stirred and then (B) is injected into (A) to emulsify and disperse, and then stirred at a temperature of 50 ° C. To (C) and cool to 30 ° C to prepare

Properties The skin creams of Examples 1 to 3 of the present invention showed good results in the above tests. On the other hand, the skin creams of Comparative Examples 1 and 2 were inferior to the Examples of the present invention, because the sufficient effect was not recognized.

Example 4 [Skin lotion] The skin lotion of the present invention having the composition shown in Table 3 was prepared by the following production method.

[0027]

[Table 3]

Preparation Method (A), (B) Each component is mixed and dissolved, and (B)
Was added to (A) and mixed and stirred to prepare.

Properties The skin lotion of this Example 4 showed good results in the above tests.

Example 5 [Day Essence] A day essence (daytime beauty essence) of the present invention having the composition shown in Table 4 was prepared by the following production method.

[0031]

[Table 4] *, **: UV absorber manufactured by Givaudan

Preparation method (A) and (B) were mixed and dissolved at 70 ° C., and (B) was added to (A), and the mixture was stirred, cooled to 50 ° C. and (C) was added. It was prepared by cooling to 30 ° C.

Characteristics The deessence of Example 6 showed good results in the above-mentioned tests.

[0034]

As described above, the present invention has an effect of preventing dark-skinned skin and quickly lightening the dark-skinned skin, and further has excellent effects of preventing rough skin, improving keratin, and preventing aging. It is clear to provide an excellent skin cosmetic which exhibits an effect and a beautiful skin effect and can keep skin healthy.

Claims (1)

[Claims] 1. Yeast and / or yeast extract and the genus Ro-saceae Pyracanth
a) a kind of Chinese name "Pyr-acant"
A skin cosmetic containing a solvent extract of the fruit of ha fortuneana).