JPH10279466A - Preparation for external use - Google Patents
Preparation for external useInfo
- Publication number
- JPH10279466A JPH10279466A JP9103867A JP10386797A JPH10279466A JP H10279466 A JPH10279466 A JP H10279466A JP 9103867 A JP9103867 A JP 9103867A JP 10386797 A JP10386797 A JP 10386797A JP H10279466 A JPH10279466 A JP H10279466A
- Authority
- JP
- Japan
- Prior art keywords
- external preparation
- water
- birch
- polyhydric alcohol
- sap
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
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- JFRJCQJVFMHZOO-QZHHGCDDSA-N n-(2-aminoethyl)-2-[4-[[2-[4-[[9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]phenyl]acetyl]amino]phenyl]acetamide Chemical compound C1=CC(CC(=O)NCCN)=CC=C1NC(=O)CC(C=C1)=CC=C1NC1=NC=NC2=C1N=CN2[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 JFRJCQJVFMHZOO-QZHHGCDDSA-N 0.000 description 1
- 239000010466 nut oil Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- PYJBVGYZXWPIKK-UHFFFAOYSA-M potassium;tetradecanoate Chemical compound [K+].CCCCCCCCCCCCCC([O-])=O PYJBVGYZXWPIKK-UHFFFAOYSA-M 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 238000007788 roughening Methods 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 230000037393 skin firmness Effects 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、外用剤に関し、更
に詳細にはカバノキ科カバノキ属樹木の樹液と水溶性高
分子及び／又は多価アルコールとを配合することによ
り、保湿及び肌あれ改善効果等を有する化粧料及び外用
医薬品等の外用剤に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an external preparation, and more particularly, to a moisturizing agent and an improvement in rough skin by blending a sap of a birch tree with a water-soluble polymer and / or a polyhydric alcohol. The present invention relates to external preparations such as cosmetics and external medicines having the above.
【０００２】[0002]
【従来の技術】従来より、乳液、クリーム、化粧水、パ
ック、洗浄料、軟膏、分散液等の外用剤には、これらに
所定の薬効を付与することを目的として薬効成分が加え
られている。肌や毛髪の荒れを改善するためには保湿効
果のある製剤を使用することが効果的であり、様々な保
湿剤が使用されてきた。又、アルギン酸等に代表される
ような水溶性高分子や、グリセリン等に代表されるよう
な多価アルコールも、保湿効果の高いものとして汎用さ
れてきた。2. Description of the Related Art Conventionally, external preparations such as emulsions, creams, lotions, packs, detergents, ointments, and dispersions have been added with a pharmaceutically active ingredient for the purpose of imparting a predetermined pharmaceutically effect to them. . In order to improve the roughness of skin and hair, it is effective to use a preparation having a moisturizing effect, and various moisturizing agents have been used. Also, water-soluble polymers such as alginic acid and polyhydric alcohols such as glycerin have been widely used as having high moisturizing effects.
【０００３】[0003]
【発明が解決しようとする課題】しかしながら、これら
の保湿剤を安全性や使用感の面から可能な範囲で配合し
ても、必ずしもその効果は十分でなく改善が望まれてい
た。However, even if these humectants are blended within the range possible from the viewpoint of safety and feeling of use, the effect is not always sufficient and improvement has been desired.
【０００４】[0004]
【課題を解決するための手段】本発明者らは、外用剤の
薬効成分の効果を向上させるべく鋭意検討を行った結
果、カバノキ科カバノキ属樹木の樹液と水溶性高分子及
び／又は多価アルコールとを組み合わせれば、十分な肌
荒れ改善効果が得られることを見出し、本発明を完成し
た。Means for Solving the Problems The present inventors have conducted intensive studies to improve the effect of the medicinal component of the external preparation, and as a result, have found that the sap of a birch tree of the birch family and a water-soluble polymer and / or polyvalent polysaccharide are obtained. It has been found that a sufficient effect of improving rough skin can be obtained by combining with alcohol, and the present invention has been completed.
【０００５】すなわち、本発明は、次の成分（Ａ）及び
（Ｂ） （Ａ）カバノキ科カバノキ属樹木の樹液 （Ｂ）水溶性高分子及び／又は多価アルコールの一種又
は二種以上を含有する外用剤を提供するものである。That is, the present invention comprises the following components (A) and (B): (A) sap of a birch tree of the birch family, (B) one or more of a water-soluble polymer and / or a polyhydric alcohol. It is intended to provide an external preparation to be used.
【０００６】[0006]
【発明の実施の形態】本発明の（Ａ）成分であるカバノ
キ科カバノキ属樹木の樹液は、当該樹木の開花・開葉期
前に樹木に穿孔することにより溢出する液体であり、近
年日本においても飲料としての利用が始められている
（化学と生物Ｖｏｌ３３，Ｎｏ１１、７５５−７６０、
１９９５；遺伝４９巻３号、４７−５３、１９９５）。
カバノキ科カバノキ属樹木としては、シラカンバ Betul
a platyphylla Sukatchev var. japonica Hara、B. pla
typhylla Sukachev、ダケカンバ B. Ermani Cham.、ジ
ゾウカンバ B. globispica Shirai、ウダイカンバ B. M
aximowicziana Regel、シルバーバーチ B. pendula Rot
h、スイートバーチ B. lenta L.等が挙げられる。BEST MODE FOR CARRYING OUT THE INVENTION The sap of a birch tree of the birch family, which is the component (A) of the present invention, is a liquid that overflows by perforating the tree before the flowering and leafing period of the tree. Has also begun to be used as a beverage (Chemistry and Biology Vol 33, No 11, 755-760,
1995; Genetics, Vol. 49, No. 3, 47-53, 1995).
For birch trees of the birch family, birch Betul
a platyphylla Sukatchev var.japonica Hara, B. pla
typhylla Sukachev, Birch Birch B. Ermani Cham., Jizou Kamba B. globispica Shirai, Udai Kamba B. M
aximowicziana Regel, silver birch B. pendula Rot
h, sweet birch B. lenta L. and the like.
【０００７】樹液は開花・開葉期前に樹木に穿孔するこ
とにより採取でき、実使用に当たっては保存性を付与す
るために適量の防腐剤等を加えることが望ましい。[0007] Sap can be collected by piercing the tree before the flowering / leafing stage, and in actual use, it is desirable to add an appropriate amount of a preservative or the like to impart preservation.
【０００８】本発明組成物におけるカバノキ科カバノキ
属樹木の樹液の含有量は、好ましくは０．０５〜９５重
量％（以下単に「％」で示す）の範囲であり、より好ま
しくは１〜４５％の範囲である。この範囲であれば、水
溶性高分子及び／又は多価アルコールの効果を相乗的に
高めることができる。The sap content of the birch tree of the birch family in the composition of the present invention is preferably in the range of 0.05 to 95% by weight (hereinafter simply referred to as "%"), more preferably 1 to 45%. Range. Within this range, the effects of the water-soluble polymer and / or polyhydric alcohol can be synergistically enhanced.
【０００９】一方、本発明の（Ｂ）成分である水溶性高
分子は、以下に示すものが挙げられる。On the other hand, examples of the water-soluble polymer as the component (B) of the present invention include the following.
【００１０】すなわち、コンドロイチン硫酸、ヒアルロ
ン酸、ムチン、デルマタン硫酸、ヘパリン及びケラタン
硫酸などのムコ多糖類及びその塩、アルギン酸及びその
塩、アラビアゴム、寒天、プルラン、カラギーナン、ロ
ーカストビーンガム、キサンタンガム、キチン、加水分
解キチン、ゼラチン、デンプン、コラーゲン、セルロー
ス、結晶セルロース、メチルセルロース、ヒドロキシプ
ロピルセルロース、ヒドロキシメチルプロピルセルロー
ス、エチルセルロース、ヒドロキシエチルセルロース、
ポリアクリル酸ナトリウム、カルボシキシメチルセルロ
ース及びその塩、ポリビニルアルコール、ポリビニルピ
ロリドン、カルボキシビニルポリマー、アルキル変性カ
ルボキシビニルポリマー、アクリル酸メタアクリル酸ア
ルキル共重合体等が挙げられる。That is, mucopolysaccharides such as chondroitin sulfate, hyaluronic acid, mucin, dermatan sulfate, heparin and keratan sulfate and salts thereof, alginic acid and salts thereof, gum arabic, agar, pullulan, carrageenan, locust bean gum, xanthan gum, chitin , Hydrolyzed chitin, gelatin, starch, collagen, cellulose, crystalline cellulose, methylcellulose, hydroxypropylcellulose, hydroxymethylpropylcellulose, ethylcellulose, hydroxyethylcellulose,
Examples thereof include sodium polyacrylate, carboxymethylcellulose and salts thereof, polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymers, alkyl-modified carboxyvinyl polymers, and alkyl methacrylate copolymers.
【００１１】上記の（Ｂ）成分である水溶性高分子の配
合量は、乾燥固形分として好ましくは０．０００５〜２
０％の範囲であり、より好ましくは０．００５〜１０％
の範囲である。この範囲であれば、優れた保湿効果と肌
あれ改善効果が得られる。The compounding amount of the water-soluble polymer as the component (B) is preferably 0.0005 to 2 as a dry solid content.
0%, more preferably 0.005 to 10%
Range. Within this range, an excellent moisturizing effect and an effect of improving skin roughness can be obtained.
【００１２】一方、本発明のもう一つの（Ｂ）成分であ
る多価アルコールは、以下に示すものが挙げられる。On the other hand, the polyhydric alcohol which is another component (B) of the present invention includes the following.
【００１３】すなわち、グリセリン、ジグリセリン、プ
ロピレングリコール、ジプロピレングリコ−ル、１，３
−ブチレングリコール、ソルビトール、エリスリトー
ル、マルチトール、キシリトール、キシロース、トレハ
ロース、イノシトール、グルコース、ポリエチレングリ
コール等が挙げられる。That is, glycerin, diglycerin, propylene glycol, dipropylene glycol, 1,3
-Butylene glycol, sorbitol, erythritol, maltitol, xylitol, xylose, trehalose, inositol, glucose, polyethylene glycol and the like.
【００１４】多価アルコールの配合量は、好ましくは
０．１〜３０％であり、より好ましくは０．１〜１０％
である。この範囲であれば、優れた保湿効果と肌あれ改
善効果が得られる。The blending amount of the polyhydric alcohol is preferably 0.1 to 30%, more preferably 0.1 to 10%.
It is. Within this range, an excellent moisturizing effect and an effect of improving skin roughness can be obtained.
【００１５】上記の（Ｂ）成分である水溶性高分子、多
価アルコールは、これらの１種又は２種以上を組み合わ
せて用いることができる。The water-soluble polymer and the polyhydric alcohol as the component (B) can be used alone or in combination of two or more.
【００１６】本発明の外用剤は、常法に従い、カバノキ
科カバノキ属樹木の樹液と水溶性高分子及び／又は多価
アルコールとを通常の外用剤として知られる種々の形態
の基剤に配合して調製することができる。The external preparation of the present invention is prepared by mixing a sap of a birch tree of the birch family and a water-soluble polymer and / or a polyhydric alcohol in various forms known as conventional external preparations according to a conventional method. Can be prepared.
【００１７】外用剤の形態の例としては、特に限定され
ず、例えば、乳液、クリーム、化粧水、パック、洗浄
料、口紅・ファンデーションなどのメーキャップ化粧
料、頭皮・頭髪用品等の化粧料、軟膏、分散液等の外用
医薬品などとすることができ、また、これら外用剤の形
態に応じ、本発明の効果を損なわない範囲で、例えば、
精製水、低級アルコール、油脂、粉体、界面活性剤、紫
外線吸収剤、色素、美容成分、防腐剤、香料等を用いる
ことができる。Examples of the form of the external preparation are not particularly limited, and include, for example, emulsions, creams, lotions, packs, cleaning agents, makeup cosmetics such as lipsticks and foundations, cosmetics such as scalp and hair supplies, ointments. External medicines such as dispersions can be used, and depending on the form of these external preparations, within the range not impairing the effects of the present invention, for example,
Purified water, lower alcohols, oils and fats, powders, surfactants, ultraviolet absorbers, pigments, cosmetic ingredients, preservatives, fragrances, and the like can be used.
【００１８】[0018]
【実施例】次に実施例を挙げて本発明を更に詳細に説明
するが、本発明はこれらになんら制約されるものではな
い。Next, the present invention will be described in more detail with reference to examples, but the present invention is not limited thereto.
【００１９】実施例１ 表１に示す組成及び下記製法で乳液（本発明品１〜４、
及び比較品１〜３）を調製し、その肌荒れ改善効果を調
べた。この結果も併せて表１に示す。Example 1 Emulsions (products of the present invention 1 to 4,
And Comparative products 1 to 3) were prepared, and their skin roughness improving effect was examined. The results are also shown in Table 1.
【００２０】（組成及び結果）(Composition and results)
【表１】 [Table 1]
【００２１】（製法） Ａ．（６）、（７）、（１０）及び（１４）の各成分を
加熱混合し、７０℃に保つ。 Ｂ．（１）〜（５）、（１１）及び（１２）の各成分を
加熱混合し、７０℃に保つ。 Ｃ．上記Ｂを先のＡに加えて混合し、成分（８）、
（９）及び（１３）を加えて均一に乳化し、３０℃まで
冷却して乳液を得た。(Production method) A. The components (6), (7), (10) and (14) are mixed by heating and maintained at 70 ° C. B. The components (1) to (5), (11) and (12) are mixed by heating and maintained at 70 ° C. C. The above B is added to the above A and mixed, and the component (8),
(9) and (13) were added to emulsify uniformly, and cooled to 30 ° C. to obtain an emulsion.
【００２２】（試験方法）２５〜５０歳の健常人２０名
をパネルにして、実験的な荒れ肌を惹起する前の肌状態
をマイクロスコープカメラで撮影し、下記基準によりそ
のスコアを求めた。実験的な荒れ肌は、上腕屈折部をエ
ーテル、アセトン（１：１）混液で処理することにより
惹起した。さらにその後は、７日間にわたって毎日、朝
と夜の２回被験乳液を塗布し、荒れ肌惹起の１、３、５
及び７日後に前記と同様肌状態のスコアを求めた。(Testing Method) Twenty healthy persons aged 25 to 50 years were used as panels, and the skin condition before inducing experimental rough skin was photographed with a microscope camera, and the score was obtained according to the following criteria. Experimental rough skin was caused by treating the upper arm bending portion with a mixture of ether and acetone (1: 1). After that, the test emulsion was applied twice a day for 7 days, in the morning and in the evening, and 1, 3, 5
After 7 days, the skin condition score was determined in the same manner as described above.
【００２３】 肌状態スコア： ［スコア］ ［状態］ １ 肌の皮構が不鮮明であり、角質のはがれが認められる。 ２ 肌の皮構がやや不鮮明であるかまたは一方向性が強い。 ３ 肌の皮構は認められるが、浅いかまたは一方向性が強い。 ４ 肌の皮構は認められるかまたはやや網目状である。 ５ 肌の皮構がはっきり認められるかまたはきれいな網目状であ る。Skin condition score: [Score] [State] 1 Skin structure of skin is unclear, and exfoliation of keratin is recognized. 2 The skin texture of the skin is slightly unclear or strongly unidirectional. 3 Skin texture is recognized, but shallow or strongly unidirectional. 4 Skin texture is noticeable or slightly reticulated. 5 The skin texture of the skin is clearly recognized or the mesh is clean.
【００２４】表１の結果に示されるように、本発明品に
代表されるシラカンバ樹液と水溶性高分子及び／又は多
価アルコールを組み合わせた乳液は、これらを皮膚に適
用することにより、肌の荒れに改善効果を示すことが明
らかになった。As shown in the results of Table 1, the birch sap represented by the product of the present invention and the emulsion containing a combination of a water-soluble polymer and / or a polyhydric alcohol were applied to the skin to obtain It has been found that roughening has an improving effect.
【００２５】実施例２ 化粧水：次に示す下記処方及び製法で化粧水を調製し
た。 （処方） （％） （１）グリセリン ６．０ （２）１，３−ブチレングリコール ５．５ （３）ポリオキシエチレン（２０Ｅ．Ｏ．）ソルビタン １．５ モノラウレート （４）エチルアルコール ９．０ （５）シラカンバ樹液＊１ ５．０ （６）ヒアルロン酸ナトリウム＊２ ２．０ （７）エリスリトール＊３ ０．２ （８）カルボキシメチルセルロース ０．１ （９）防腐剤 適量 （１０）香料 適量 （１１）精製水 残量 ＊１ 北海道美深町産 ＊２ キューピー社製 ＊３ 日研化学社製Example 2 Lotion: A lotion was prepared according to the following formulation and manufacturing method. (Prescription) (%) (1) Glycerin 6.0 (2) 1,3-butylene glycol 5.5 (3) Polyoxyethylene (20EO) sorbitan 1.5 monolaurate (4) Ethyl alcohol 9 0.0 (5) Birch sap * 1 5.0 (6) Sodium hyaluronate * 2 2.0 (7) Erythritol * 3 0.2 (8) Carboxymethylcellulose 0.1 (9) Preservatives Appropriate amount (10) Fragrance Appropriate amount (11) Remaining purified water * 1 From Bifuka-cho, Hokkaido * 2 Made by Kewpie * 3 Made by Niken Kagaku
【００２６】（製法） Ａ．成分（３）、（４）及び（６）〜（１０）を混合溶
解する。 Ｂ．成分（１）、（２）、（５）及び（１１）を混合溶
解する。 Ｃ．ＡとＢを混合して均一にし、化粧水を得た。(Production method) A. Components (3), (4) and (6) to (10) are mixed and dissolved. B. Components (1), (2), (5) and (11) are mixed and dissolved. C. A and B were mixed and made uniform to obtain a lotion.
【００２７】実施例３ 乳液：次に示す下記処方及び製法で乳液を調製した。 （処方） （％） （１）ポリオキシエチレン（１０Ｅ．Ｏ．）ソルビタン １．０ モノステアレート （２）ポリオキシエチレン（６０Ｅ．Ｏ．）ソルビタン ０．５ テトラオレエート （３）グリセリルモノステアレート １．０ （４）ステアリン酸 ０．５ （５）ベヘニルアルコール ０．５ （６）スクワラン ８．０ （７）シルバーバーチ樹液＊１ ２０．０ （８）キサンタンガム ５．０ （９）防腐剤 ０．１ （１０）ローカストビーンガム ０．１ （１１）水酸化ナトリウム ０．０５ （１２）エチルアルコール ５．０ （１３）精製水 残量 （１４）香料 適量 ＊１ フィンランド産Example 3 Emulsion: An emulsion was prepared according to the following formulation and production method. (Formulation) (%) (1) Polyoxyethylene (10EO) sorbitan 1.0 monostearate (2) Polyoxyethylene (60EO) sorbitan 0.5 tetraoleate (3) Glyceryl monostearate Rate 1.0 (4) Stearic acid 0.5 (5) Behenyl alcohol 0.5 (6) Squalane 8.0 (7) Silver birch sap * 1 20.0 (8) Xanthan gum 5.0 (9) Preservative 0 .1 (10) Locust bean gum 0.1 (11) Sodium hydroxide 0.05 (12) Ethyl alcohol 5.0 (13) Remaining purified water (14) Perfume appropriate amount * 1 Finnish
【００２８】（製法） Ａ．成分（８）、１０）〜（１３）を加熱混合し、７０
℃に保つ。 Ｂ．成分（１）〜（６）を加熱混合し、７０℃に保つ。 Ｃ．ＢにＡを加えて混合し、均一に乳化する。 Ｄ．Ｃを冷却後、成分（７）、（９）、（１４）を加
え、均一に混合して乳液を得た。(Production method) A. The components (8), 10) to (13) are mixed by heating.
Keep at ° C. B. The components (1) to (6) are mixed by heating and kept at 70 ° C. C. Add A to B, mix and emulsify uniformly. D. After cooling C, components (7), (9) and (14) were added and mixed uniformly to obtain an emulsion.
【００２９】実施例４ クリーム：次に示す下記処方及び製法でクリームを調製
した。 （処方） （％） （１）マイクロクリスタリンワックス ４．０ （２）セタノール ３．０ （３）ワセリン ３．０ （４）スクワラン １５．０ （５）マカデミアナッツ油 １０．０ （６）親油型モノステアリン酸グリセリン １．５ （７）ポリオキシエチレンソルビタン モノオレイン酸エステル（２０Ｅ．Ｏ．） １．０ （８）グリセリン ５．０ （９）１，３−ブチレングリコール １０．０ （１０）ダケカンバ樹液＊１ ４５．０ （１１）防腐剤 ０．２ （１２）香料 ０．０５ （１３）精製水 残量 ＊１ 韓国産Example 4 Cream: A cream was prepared according to the following formulation and manufacturing method. (Prescription) (%) (1) Microcrystalline wax 4.0 (2) Cetanol 3.0 (3) Vaseline 3.0 (4) Squalane 15.0 (5) Macadamia nut oil 10.0 (6) Lipophilic type Glycerin monostearate 1.5 (7) Polyoxyethylene sorbitan monooleate (20EO) 1.0 (8) Glycerin 5.0 (9) 1,3-butylene glycol 10.0 (10) Bamboo birch Sap * 1 45.0 (11) Preservative 0.2 (12) Fragrance 0.05 (13) Purified water Remaining * 1 Made in Korea
【００３０】（製法） Ａ．成分（１）〜（７）、及び（１１）を混合し、加熱
して７０℃に保つ。 Ｂ．成分（８）〜（１０）及び（１３）を混合し、加熱
して７０℃に保つ。 Ｃ．ＡにＢを加え、混合した後、冷却して成分（１２）
を加えて、均一に混合して、クリームを得た。(Production method) A. Components (1) to (7) and (11) are mixed and heated to 70 ° C. B. Components (8)-(10) and (13) are mixed and heated to 70 ° C. C. Add B to A, mix and cool, then cool component (12)
Was added and mixed uniformly to obtain a cream.
【００３１】実施例５ ゲル軟膏：次に示す処方及び下記製法でゲル軟膏を調製
した。 （処方） （％） （１）カルボキシビニルポリマー ０．５ （２）トリエタノールアミン １．０ （３）１，３−ブチレングリコール １０．０ （４）シラカンバ樹液＊１ １．０ （５）ヘパリン＊２ ０．０１ （６）キシリトール＊３ ０．１ （７）精製水 残量 ＊１ 北海道美深町産 ＊２ 生化学工業社製 ＊３ 日研化学社製Example 5 Gel ointment: A gel ointment was prepared according to the following formulation and the following method. (Prescription) (%) (1) Carboxyvinyl polymer 0.5 (2) Triethanolamine 1.0 (3) 1,3-butylene glycol 10.0 (4) Birch sap * 1 1.0 (5) Heparin * 2 0.01 (6) Xylitol * 3 0.1 (7) Remaining purified water * 1 Bifuka-cho, Hokkaido * 2 Seikagaku Corporation * 3 Niken Chemical Co., Ltd.
【００３２】（製法） Ａ．成分（１）及び（３）〜（７）を混合溶解する。 Ｂ．Ａに成分（２）を加え均一にし、ゲル軟膏を得た。(Production method) A. The components (1) and (3) to (7) are mixed and dissolved. B. The component (2) was added to A to make it uniform, and a gel ointment was obtained.
【００３３】実施例２の化粧水、実施例３の乳液、実施
例４のクリーム及び実施例５のゲル軟膏は、いずれも経
時安定性に優れ、これらを皮膚に適用することにより、
皮膚のキメを整え、皮膚水分量が適度に保たれ、肌の
「くすみ」等の防止、改善することができることができ
るとともに、肌のはり、つやが改善され、美しい肌とす
るものであった。The lotion of Example 2, the emulsion of Example 3, the cream of Example 4, and the gel ointment of Example 5 are all excellent in stability over time, and by applying these to the skin,
The skin texture was adjusted, the skin moisture content was maintained at an appropriate level, and it was possible to prevent and improve "dullness" and the like of the skin, as well as to improve the skin firmness and luster, and to make the skin beautiful. .
【００３４】実施例６ パック：次に示す処方及び下記製法でパックを調製し
た。 （処方） （％） （１）ポリビニルアルコール １５．０ （２）エチルアルコール ２０．０ （３）グリセリン ５．０ （４）カオリン ６．０ （５）スイートバーチ樹液＊１ ３．０ （６）マルチトール＊２ ０．２ （７）防腐剤 適量 （８）香料 適量 （９）精製水 残量 ＊１ フィンランド産 ＊２ 林原生物化学研究所製Example 6 Pack: A pack was prepared according to the following formulation and the following production method. (Prescription) (%) (1) Polyvinyl alcohol 15.0 (2) Ethyl alcohol 20.0 (3) Glycerin 5.0 (4) Kaolin 6.0 (5) Sweet birch sap * 1 3.0 (6) Maltitol * 2 0.2 (7) Preservative appropriate amount (8) Flavor appropriate amount (9) Purified water Remaining * 1 Finnish * 2 Hayashibara Biochemical Laboratory
【００３５】（製法） Ａ．成分（１）、（３）〜（６）及び（９）を混合し、
７０℃に加熱し、攪拌する。 Ｂ．成分（２）、（７）及び（８）を混合する。 Ｃ．上記Ｂを先のＡに加え、混合した後、冷却してパッ
クを得た。(Production method) Mixing the components (1), (3) to (6) and (9),
Heat to 70 ° C. and stir. B. Mix components (2), (7) and (8). C. The above B was added to the above A, mixed, and then cooled to obtain a pack.
【００３６】実施例６のパックは、経時安定性に優れ、
これを皮膚にすることにより、皮膚のキメを整え、皮膚
水分量が適度に保たれ、肌の「くすみ」等の防止、改善
することができるとともに、肌のはり、つやが改善さ
れ、美しい肌とするものであった。The pack of Example 6 has excellent stability over time,
By using this as the skin, the texture of the skin can be adjusted, the moisture content of the skin can be kept at an appropriate level, the skin can be prevented or improved from dullness, etc. It was to be.
【００３７】実施例７ シャンプー：次に示す処方及び下記製法でシャンプーを
調製した。 （処方） （％） （１）Ｎ−ヤシ油脂肪酸グルタミン酸トリエタノールアミン ２５．０ （２）ラウリン酸ジエタノールアミド ５．０ （３）ミリスチン酸カリウム ５．０ （４）ジステアリン酸エチレングリコール ２．０ （５）ポリエチレングリコール４００ １５．０ （６）ジメチルポリシロキサン １．０ （７）シルバーバーチ樹液 ＊１ １２．０ （８）アルギン酸＊２ ０．０２ （９）加水分解キチン＊３ ０．０２ （１０）防腐剤 適量 （１１）香料 適量 （１２）色素 適量 （１３）精製水 残量 ＊１ フィンランド産 ＊２ シグマ社製 ＊３ 一丸ファルコス社製Example 7 Shampoo: A shampoo was prepared according to the following formulation and the following method. (Prescription) (%) (1) N-coconut oil fatty acid triethanolamine glutamate 25.0 (2) lauric acid diethanolamide 5.0 (3) potassium myristate 5.0 (4) ethylene glycol distearate 2.0 (5) polyethylene glycol 400 15.0 (6) dimethyl polysiloxane 1.0 (7) silver birch sap * 1 12.0 (8) alginic acid * 2 0.02 (9) hydrolyzed chitin * 3 0.02 ( 10) Preservative appropriate amount (11) Flavor appropriate amount (12) Dye appropriate amount (13) Purified water Remaining * 1 Finnish * 2 Sigma * 3 Ichimaru Falcos
【００３８】（製法） Ａ．成分（１）〜（５）及び（１３）を加熱混合し、均
一に溶解する。 Ｂ．Ａを冷却し、成分（６）〜（１２）を添加して均一
に混合してシャンプーを得た。(Production method) The components (1) to (5) and (13) are mixed by heating and uniformly dissolved. B. A was cooled, and components (6) to (12) were added and mixed uniformly to obtain a shampoo.
【００３９】実施例７のシャンプーは、経時安定性に優
れ、また洗い流した後のツッパリ感がなく、保湿性に優
れるもので、使用後のコンディショニング効果も良好で
あった。The shampoo of Example 7 was excellent in stability over time, did not have a crisp feeling after washing, was excellent in moisture retention, and had a good conditioning effect after use.
【００４０】[0040]
【発明の効果】以上記述したように、カバノキ科カバノ
キ属樹木の樹液と水溶性高分子及び／又は多価アルコー
ルを組み合わせることにより、肌あれ防止効果を十分に
発揮させることができ、また非常に高い保湿効果を得る
ことができる。従って、本発明の外用剤は極めて有用な
ものである。As described above, by combining the sap of the birch tree of the birch family with the water-soluble polymer and / or polyhydric alcohol, it is possible to sufficiently exert the effect of preventing rough skin, and A high moisturizing effect can be obtained. Therefore, the external preparation of the present invention is extremely useful.
フロントページの続き (51)Int.Cl.6 識別記号 ＦＩ // Ａ６１Ｋ 35/78 ＡＤＡ Ａ６１Ｋ 35/78 ＡＤＡＣ Continued on the front page (51) Int.Cl. 6 Identification symbol FI // A61K 35/78 ADA A61K 35/78 ADAC
Claims (3)
は二種以上を含有することを特徴とする外用剤。1. The following components (A) and (B): (A) a sap of a birch tree of the birch family, (B) one or more water-soluble polymers and / or polyhydric alcohols. External preparation.
アルロン酸、ムチン、デルマタン硫酸、ヘパリン及びケ
ラタン硫酸から選ばれるムコ多糖類及びその塩、アルギ
ン酸及びその塩、アラビアゴム、寒天、プルラン、カラ
ギーナン、ローカストビーンガム、キサンタンガム、キ
チン、加水分解キチン、ゼラチン、デンプン、コラーゲ
ン、セルロース、結晶セルロース、メチルセルロース、
ヒドロキシプロピルセルロース、ヒドロキシメチルプロ
ピルセルロース、エチルセルロース、ヒドロキシエチル
セルロース、ポリアクリル酸ナトリウム、カルボシキシ
メチルセルロース及びその塩、ポリビニルアルコール、
ポリビニルピロリドン、カルボキシビニルポリマー、ア
ルキル変性カルボキシビニルポリマー、アクリル酸メタ
アクリル酸アルキル共重合体より選ばれた請求項１記載
の外用剤。2. A mucopolysaccharide whose water-soluble polymer is selected from chondroitin sulfate, hyaluronic acid, mucin, dermatan sulfate, heparin and keratan sulfate and its salts, alginic acid and its salts, gum arabic, agar, pullulan, carrageenan, locust Bean gum, xanthan gum, chitin, hydrolyzed chitin, gelatin, starch, collagen, cellulose, crystalline cellulose, methylcellulose,
Hydroxypropylcellulose, hydroxymethylpropylcellulose, ethylcellulose, hydroxyethylcellulose, sodium polyacrylate, carboxymethylcellulose and its salts, polyvinyl alcohol,
The external preparation according to claim 1, wherein the external preparation is selected from polyvinylpyrrolidone, carboxyvinyl polymer, alkyl-modified carboxyvinyl polymer, and alkyl methacrylate copolymer.
リン、プロピレングリコール、ジプロピレングリコ−
ル、１，３−ブチレングリコール、ソルビトール、エリ
スリトール、マルチトール、キシリトール、キシロー
ス、トレハロース、イノシトール、グルコース、ポリエ
チレングリコールから選ばれた請求項１記載の外用剤。3. The polyhydric alcohol is glycerin, diglycerin, propylene glycol, dipropylene glyco-
2. The external preparation according to claim 1, wherein the external preparation is selected from the group consisting of toluene, 1,3-butylene glycol, sorbitol, erythritol, maltitol, xylitol, xylose, trehalose, inositol, glucose and polyethylene glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9103867A JPH10279466A (en) | 1997-04-07 | 1997-04-07 | Preparation for external use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9103867A JPH10279466A (en) | 1997-04-07 | 1997-04-07 | Preparation for external use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH10279466A true JPH10279466A (en) | 1998-10-20 |
Family
ID=14365399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9103867A Pending JPH10279466A (en) | 1997-04-07 | 1997-04-07 | Preparation for external use |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH10279466A (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001048769A (en) * | 1999-08-05 | 2001-02-20 | Shiseido Co Ltd | Skin lotion |
| JP2001081008A (en) * | 1999-07-15 | 2001-03-27 | Shiseido Co Ltd | Skin preparation for external use keeping and improving the skin from chapping |
| JP2002356406A (en) * | 2001-05-29 | 2002-12-13 | Noevir Co Ltd | External preparation for skin |
| FR2829695A1 (en) * | 2001-09-14 | 2003-03-21 | Sederma Sa | Cosmetic and dermatological compositions, useful for care of the skin, mucosa and attachments, i.e. nails, body or head hair, comprise birch sap |
| JP2003292433A (en) * | 2002-02-01 | 2003-10-15 | Masayoshi Kachi | Cosmetic |
| JP2005502664A (en) * | 2001-08-27 | 2005-01-27 | エル・ヴェ・エム・アッシュ ルシェルシュ | Cosmetic composition that has the effect of tightening the skin |
| JP2007223954A (en) * | 2006-02-24 | 2007-09-06 | Kose Corp | Cholesterol production promoter and skin external preparation containing the same |
| JP2007230933A (en) * | 2006-03-02 | 2007-09-13 | Kose Corp | Cell-activating agent and external preparation for skin including the same |
| JP2007320921A (en) * | 2006-06-01 | 2007-12-13 | Nitta Gelatin Inc | Cosmetic comprising sap formulated therein |
| KR20150070100A (en) * | 2012-08-13 | 2015-06-24 | 바스프 뷰티 케어 솔루션즈 프랑스 에스에이에스 | Cosmetic or pharmaceutical moisturising ingredient |
| JP2017505344A (en) * | 2014-02-10 | 2017-02-16 | トロイカ ファーマスーティカルズ リミテッド | Topical heparin formulation |
| EP3498259A4 (en) * | 2017-04-27 | 2019-08-28 | Yang Sheng Tang (Shanghai) Cosmetic R&D Co., Ltd. | MOISTURIZING COSMETIC PRODUCT COMPOSITION |
| EP3510993A4 (en) * | 2017-04-27 | 2020-06-03 | Yang Sheng Tang (Shanghai) Cosmetic R&D Co., Ltd. | Skin care cosmetic composition |
| JP2021514349A (en) * | 2018-02-08 | 2021-06-10 | エルジー ハウスホールド アンド ヘルスケア リミテッド | A composition for improving the optical properties of the skin, which contains a light scattering reducing substance. |
-
1997
- 1997-04-07 JP JP9103867A patent/JPH10279466A/en active Pending
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001081008A (en) * | 1999-07-15 | 2001-03-27 | Shiseido Co Ltd | Skin preparation for external use keeping and improving the skin from chapping |
| JP2001048769A (en) * | 1999-08-05 | 2001-02-20 | Shiseido Co Ltd | Skin lotion |
| JP2002356406A (en) * | 2001-05-29 | 2002-12-13 | Noevir Co Ltd | External preparation for skin |
| US7700084B2 (en) | 2001-08-27 | 2010-04-20 | Lvmh Recherche | Cosmetic composition with skin tightening effect |
| JP2005502664A (en) * | 2001-08-27 | 2005-01-27 | エル・ヴェ・エム・アッシュ ルシェルシュ | Cosmetic composition that has the effect of tightening the skin |
| US8986667B2 (en) | 2001-08-27 | 2015-03-24 | Lvmh Recherche | Cosmetic composition with skin tightening effect |
| FR2829695A1 (en) * | 2001-09-14 | 2003-03-21 | Sederma Sa | Cosmetic and dermatological compositions, useful for care of the skin, mucosa and attachments, i.e. nails, body or head hair, comprise birch sap |
| WO2003024418A3 (en) * | 2001-09-14 | 2003-11-27 | Sederma Sa | Use of birch sap in cosmetic and dermopharmaceutical compositions |
| JP2003292433A (en) * | 2002-02-01 | 2003-10-15 | Masayoshi Kachi | Cosmetic |
| JP2007223954A (en) * | 2006-02-24 | 2007-09-06 | Kose Corp | Cholesterol production promoter and skin external preparation containing the same |
| JP2007230933A (en) * | 2006-03-02 | 2007-09-13 | Kose Corp | Cell-activating agent and external preparation for skin including the same |
| JP2007320921A (en) * | 2006-06-01 | 2007-12-13 | Nitta Gelatin Inc | Cosmetic comprising sap formulated therein |
| KR20150070100A (en) * | 2012-08-13 | 2015-06-24 | 바스프 뷰티 케어 솔루션즈 프랑스 에스에이에스 | Cosmetic or pharmaceutical moisturising ingredient |
| JP2017505344A (en) * | 2014-02-10 | 2017-02-16 | トロイカ ファーマスーティカルズ リミテッド | Topical heparin formulation |
| EP3498259A4 (en) * | 2017-04-27 | 2019-08-28 | Yang Sheng Tang (Shanghai) Cosmetic R&D Co., Ltd. | MOISTURIZING COSMETIC PRODUCT COMPOSITION |
| EP3510993A4 (en) * | 2017-04-27 | 2020-06-03 | Yang Sheng Tang (Shanghai) Cosmetic R&D Co., Ltd. | Skin care cosmetic composition |
| US10799445B2 (en) | 2017-04-27 | 2020-10-13 | Yang Sheng Tang (Shanghai) Cosmetic R&D Co., Ltd. | Moisturizing cosmetic composition |
| EP4062900A3 (en) * | 2017-04-27 | 2023-08-09 | Yang Sheng Tang (Shanghai) Cosmetic R&D Co., Ltd. | Skin care cosmetic composition |
| JP2021514349A (en) * | 2018-02-08 | 2021-06-10 | エルジー ハウスホールド アンド ヘルスケア リミテッド | A composition for improving the optical properties of the skin, which contains a light scattering reducing substance. |
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