JPH1045566A - Body wash containing yucca extract and method for producing the same - Google Patents

Abstract

(57) [Summary] [PROBLEMS] To provide a body cleansing agent which is excellent in foaming property, moisturizing property and antibacterial property, prevents rough skin and matting, and keeps beautiful skin, and a method for producing the same. SOLUTION: The personal cleansing agent is characterized by containing a Yucca extract. In the extract, saponin, flavone,
Resveratrol can be included. Assuming that the total amount of the cleaning base material and the evaporation residue of the yucca extract in this body cleansing agent is 100% by weight, saponin, flavone, and resveratro-
The content of the metal can be 0.01 to 5% by weight. The method for producing the body cleansing agent is as follows. At least one of roots and stems of yucca is dried into chips, or dried and chips are crushed into powder, and the powder is a low-grade one having 1 to 3 carbon atoms. It is characterized in that it is immersed and extracted in alcohol or a mixed solvent of the above-mentioned alcohol and water to obtain a Yucca extract, and the extract is blended. The mixed solvent may have a mixing ratio of 75% by weight or more of alcohol.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a personal cleansing agent and a method for producing the same, and more specifically, it has excellent foaming properties, moisturizing properties and antibacterial properties, and prevents rough skin due to athlete's foot and the like, general rough skin and delustering, The present invention relates to a body cleansing agent for keeping beautiful skin and a method for producing the same.

[0002]

2. Description of the Related Art A conventional body cleansing agent is composed of a soap main component obtained by saponifying oils and fats with caustic alkali and a fragrance. For this purpose, for example, rice bran and Enmei skin extract Licorice extract and the like. In addition, there is a body shampoo containing amino acids, fatty acids, higher alcohols and the like as a main component, to which the above-mentioned additives are added. However, none of these body cleansing agents has a combination of excellent foaming, moisturizing and antibacterial properties.

[0003]

DISCLOSURE OF THE INVENTION The present invention is to solve the above-mentioned problems of the prior art and is excellent in foaming property, moisturizing property and antibacterial property, and prevents rough skin due to athlete's foot and the like, general rough skin and delustering. An object of the present invention is to provide a body cleansing agent for preventing and maintaining beautiful skin and a method for producing the same.

[0004]

[Means for Solving the Problems] In order to achieve the above-mentioned object, the present inventor has diligently studied the characteristics of the components of the plant extract, and as a result, blended the Yucca extract into a personal cleansing agent and foamed it. The present inventors have found that a body cleanser having excellent properties and moisturizing properties can be obtained, and that this extract contains saponin, flavone and resveratrol, thereby completing the present invention.

[0005] The body wash of the first invention is a Yucca (Yu)
cca) It contains an extract. The above-mentioned “Yucca” includes Yucca sidigera (Yucca sc
hidigera), Yucca arabolicene (Yucca)
arabolescenes), Yucca glorosa Linn, Yucca recurvifolia Sa
Lisb), Itlan (Yucca smalllian)
a Fernald), Senjuran (Yucca a)
loifolia Linn) or the like can be used. Also,
One of these may be used, or two or more of these may be used. The "Yucca extract" may be the extract itself obtained by extracting the raw yucca with a predetermined extraction solvent, or a concentrated solution obtained by concentrating this extract, or obtained by drying these. It may be a solid matter (the shape of which does not matter, such as powder and granules).

The yucca extract may contain saponin, flavone and resveratrol. In the body cleanser of the present invention, saponin,
Flavones and polyhydroxystilbene improve foaming and moisturizing properties by a combined effect. Saponin has an antibacterial action against yeast and skin-type filamentous fungi (causal bacteria such as athlete's foot) as well as foaming properties and moisturizing properties. Flavones generally dilate peripheral blood vessels to facilitate blood circulation. Polyhydroxystilbene, especially resveratrol (3, 4 ',
5-trihydroxystilbene) has a whitening effect by inhibiting tyrosinase activity.

As shown in the third aspect of the present invention, the saponin, flavone and resveratrol contents are 100% based on the total amount of the detergent base in the body wash and the evaporation residue of the yucca extract.
When it is defined as weight%, it may be 0.01 to 5 weight%, (preferably 0.05 to 1 weight%). This is because if the content of the substance is less than 0.01% by weight, the effect of the substance is not sufficiently exhibited, and if the content exceeds 5% by weight, defects such as coloring and a slight odor appear.

In the method for producing a personal cleansing agent according to the fourth aspect of the present invention, at least one of the roots and stems of Yucca is diced and dried, or after diced and dried, pulverized to produce a powder. Then, the powder has 1 carbon
To 3 or lower alcohol having 1 to 3 carbon atoms or a mixed solvent of lower alcohol having 1 to 3 carbon atoms and water to obtain a yucca extract, and then the yucca extract is blended. And The above "Yucca" has the same meaning as described above. As the yucca raw material, a root or a stem can be used, but usually both of them are used.

The mixed solvent of a lower alcohol having 1 to 3 carbon atoms and water has a mixing ratio of at least 75% by weight of a lower alcohol having 1 to 3 carbon atoms as shown in the fifth invention. Can be The lower alcohol is 7
If the content is less than 5% by weight, the ratio of the saponin component is low because the extracted component contains a large amount of sugar, and the extraction of yucca takes too much time, resulting in an impossibility rate. Further, the form of the above-mentioned “Yucca extract” may be an extract, a concentrate or a solid as described above.

The bases of the body wash of the present invention and the detergent produced by the production method of the present invention include alkali metal salts of higher fatty acids (sodium soap, potassium soap, etc.), ammonia salts of higher fatty acids, and higher fatty acids. Examples thereof include organic base salts (triethanolamine soap, etc.), higher alcohol-based neutral detergents, imidazoline-based amphoteric surfactants, and the like. The form of the body wash is not particularly limited, and may be, for example, a solid body (solid soap etc.), a liquid body (liquid soap or neutral detergent etc.) and the like. In addition, if necessary for the body wash, various additives that are generally used, for example, enhancers, fragrances, colorants, fluorescent bleaches, water softeners, bactericides,
Antioxidants and the like can be added.

[0011]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples. The following methods were used to prepare the yucca extract, the body cleansing agent (makeup soap) and its performance evaluation. (1) Preparation of Yucca extract Yucca sizzidger
The root and stem of a) were cut into chips, dried in the sun, and then crushed to obtain a bulk powder. 100 g of the bulk powder was immersed in a 5-fold amount of 90% methanol (10% is water), allowed to stand at room temperature for 24 hours, and filtered to obtain a 90% methanol extract.
This 90% methanol extract was heated at atmospheric pressure to give methanol.
Then, a concentrated liquid having an evaporation residue of 40 to 50% by weight was obtained.

[0012] The concentrated liquid 200 having the evaporation residue of 40 to 50%
g using a column filled with ion exchange resin (trade name “Diaion HP20” manufactured by Mitsubishi Chemical Corporation) using water,
The fraction was developed and developed sequentially with 0% methanol and 80% methanol. Water and 30% methanol extract mainly contain sugar components, and 80% methanol extract mainly contains saponin, flavone and resveratrol. 80% of this
Methanol was distilled off from the methanol extract at normal pressure in the initial stage and under reduced pressure in the latter half to obtain a concentrated solution having a residue of evaporation of 40 to 50% (referred to as "Yucca extract 1"). . Furthermore,
The concentrated solution was dried under vacuum to obtain 10 g of a brown powder (referred to as "Yucca extract 2"). The main components of this powder are saponin (87-90% by weight in dry powder), flavone (10-8% by weight in dry powder) and resveratrol (3-2% by weight in dry powder). The weight ratio of this saponin, flavone and resveratrol is about 40: 4: 1. The powder was dispersed in water and analyzed by HPLC (High Performance Liquid Chromatography) to find that it consisted of 10 to 11 components. In this analysis, the developing solvent was methanol, and the column was "ASAHIPAK, GS-
320 ".

When the raw powder obtained from Yucca is immersed in 80% to 90% methanol, an extract containing three components of saponin, flavone and resveratrol is obtained. Water alone, 3
With 0% methanol, the above three components are not extracted,
It is considered that 40% or more of methanol is required. Therefore,
To obtain an extract containing the above three components, 40-90%
Methanol, preferably 50 to 90% methanol, and more preferably 70 to 90% methanol can be applied.

(2) Preparation of toilet soap The toilet soap (solid soap) of Example 1 is refined from coconut oil, refined coconut oil and refined tallow to produce refined tallow, and 20 g of the refined coconut oil and the refined tallow are refined. 80g
Were mixed, and while heating and stirring, a saponification reaction was carried out by adding 35 g of an aqueous solution of about 50% sodium hydroxide. After completion of the saponification, salt was added, and heating and stirring were continued.
After leaving it to stand (salting out), it is treated with a soap base (new sodium salt).
It's called. ) Got. Thereafter, the neat soap was dried in a dryer to adjust the water content to about 15% to obtain a soap base. This soap base is put into a mixer, and a total of 100% by weight of the soap base in the soap base and the evaporation residue of Yucca extract
On the other hand, the yucca extract 1 was added in an amount of 0.6% by weight in solid content, mixed and then molded by an extruder to obtain 123 g of makeup soap (solid soap).

[0015] Cosmetic soap (solid soap) of Example 2 Purified coconut oil 40 g, refined tallow 6 in the same manner as the above formulation
0 g was used to obtain a soap base, and 0.6% of yucca extract 2 was added to obtain 125 g of makeup soap. This was slightly softer than that of Example 1, and soap with fine bubbles was obtained.

Decorative soap (liquid soap) of Example 3 100 g of refined coconut oil obtained by refining coconut oil was subjected to a saponification reaction using 50 g of an aqueous 48% potassium hydroxide solution to obtain a soap material. 1.0% by weight of the 40% evaporation residue of Yucca extract 1 and 0% of the sequestering agent were used based on 100% by weight of the total evaporation residue of the soap base and the yucca extract in the soap. 0.7% by weight was added and mixed, and the water content was adjusted to obtain 300 g of toilet soap (liquid soap) having a solid content of 40%.

Liquid body shampoo of Example 4 imidazoline-based amphoteric surfactant (30% liquid): 40 parts by weight, betaine-based amphoteric surfactant (30% liquid): 6 parts by weight, amino acid-based anionic surfactant ( 3% liquid): 4 parts by weight, fatty acid-based nonionic surfactant: 4 parts by weight, paraben: 0.2 parts by weight, fragrance: 0.1 parts by weight, and water: balance to prepare a composition. The yucca extract 1 was added to 0.
3 parts by weight was added and mixed well to obtain a uniform body shampoo.

(3) Performance Evaluation The following performance tests were conducted to clarify the performance of this soap. The items and methods of the performance test are as follows. Detergency The detergency was evaluated according to JIS K3362 "Synthetic detergent test method". That is, according to the method for evaluating the detergency of a synthetic detergent for clothing, an indicator detergent solution for judging detergency; detergent anhydrous 1.33
g was dissolved in 1000 ml of water to prepare a test solution having the same concentration as that of the test solution, and the evaluation results of three judges were obtained. Table 1 shows the results. The display of evaluation represents the frequency of evaluation points.

[0019]

[Table 1]

The foam stability was evaluated based on the same test method of JIS K3362 as the foaming power and foam stability. The test liquid was prepared by comparing the solid soap of Example 1 and the solid body concentration of the liquid body shampoo of Example 3 to 0.25 and 4.0 (Example 3 only). Table 2 shows the results.

[0021]

[Table 2]

Feeling on use The feeling on the skin during and after use was evaluated. The evaluation criteria are ⊚: the skin feels moist, ◯: the skin feels light and normal, and x: the skin feels dry. Appearance Change After using about 50% of the solid soap, the appearance was visually evaluated. The criteria for evaluation are as follows: ◯: No cracking occurred, Δ: Fine cracking occurred. By the above performance test, performance comparison between the solid soap obtained in Example 1 and general solid soap (Comparative Example 1) and performance between the liquid soap obtained in Example 2 and general liquid soap (Comparative Example 2) A comparison was made. Table 3 shows the results.

[0023]

[Table 3]

The following can be seen from Table 1. That is, makeup soap containing Yucca extract 1 (Examples 1 and 2)
When used, the foaming property and the moisturizing property are excellent as compared with the case where the makeup soap without the yucca extract 1 (Comparative Examples 1 and 2) is used.

(4) Evaluation of Whitening Effect of Resveratrol In order to observe the whitening effect of resveratrol, the effect of resveratrol on B16 melanoma cells having melanin-producing ability was examined. The resveratrol used in this test was an organic synthetic product (purity: 98% by weight). (Test method) 1) Cell culture The B16 melanoma cell solution was transferred to a culture flask 25 cm ² , 4 ml of culture solution (DMEM containing 10% FBS) was added, and 37 ° C., 5% -CO ₂ /95% -air was added. Cultured under the conditions. When the cells become semi-confluent, collect the cells by trypsinization, 5 × 10 ⁴ cells / 1
The cells were seeded on a 96-well multiplate so that the volume became 00 μl, and cultured again under the conditions of 37 ° C., 5% -CO ₂ /95% -air for 24 hours.

2) Measurement of tyrosinase biosynthesis inhibitory action After culturing in a 96-well multiple plate for 24 hours, the culture solution was removed, 195 μl of a new culture solution and 5 μl of a sample solution of each concentration were added, and the mixture was stirred for 60 minutes. 10 mM DOPA
/ PBS solution (100 μl) at 37 ° C., 5% -CO ₂
Incubate for 3 hours under the condition of / 95% -air,
The absorbance was measured at a wavelength of 475 nm. Tyrosinase biosynthesis inhibition rate (%) = [(AB) / A]
× 100 A; Absorbance without sample addition B: Absorbance with sample addition

3) Measurement of cell viability After culturing in a 96-well multiplate for 24 hours, the culture solution was removed, 195 μl of a new culture solution and 5 μl of a sample solution of each concentration were added, and the mixture was incubated at 37 ° C. and 5% CO ₂ / CO ₂ / CO ₂ . 95% -ai
Culture was performed for 24 hours under the conditions of r. After 24 hours, the culture solution containing the sample was removed, washed with PBS, and the MTT-containing medium 10 was added.
0 μl was added and incubated for 4 hours. 4 hours later,
The culture solution was removed, 200 μl of isopropyl alcohol was added, and the mixture was allowed to stand for 30 minutes, and the absorbance was measured at wavelengths of 570 nm and 655 nm. Cell viability (%) = (Y / X) × 100 X; value of absorbance without sample (570 nm-655 nm) Y; absorbance with sample added (570 nm-655 n)
Value of m) As the sample solution, 50% aqueous ethanol solution was used.

(Test Results) Table 4 shows the test results. The following can be seen from Table 4. That is, resveratro-
At a concentration of 10 ppm, a tyrosinase biosynthesis inhibition rate of 51.4% was observed, and the cell viability was 10%.
No cytotoxicity was observed at 0.3%. It is 5
Even at ppm, no cytotoxicity was observed at all, and a relatively excellent inhibition rate of 22.1% was shown. On the other hand, when it was 50 ppm or more, it showed an excellent inhibition rate and a certain degree of cytotoxicity at a cell survival rate of 32.3%. Further, when it is 100 ppm or more, the cell viability is as low as 8.4%, and thus cytotoxicity is strongly recognized, and when it is 1 ppm or less, the inhibition rate is 1.2% or less, which is excellent whitening. There was no effect.

As described above, when the concentration is 5 to 50 ppm, the cytotoxicity is suppressed to a certain degree or more,
Excellent whitening effect over a certain level. Of these, particularly at 5 to 10 ppm, no cytotoxicity was observed, and a certain degree of whitening effect was exhibited. Furthermore, from the above results, the concentration is 3-40.
When it is in ppm, it is possible to obtain an excellent balance between the tyrosinase biosynthesis inhibitory effect and the cytotoxicity reducing property.

[0030]

[Table 4]

(5) Comprehensive Evaluation The effects of adding saponin, flavone and resveratrol contained in the yucca extract to cosmetic soap will be summarized. This soap containing saponin, flavone and resveratrol is excellent in foaming property and moisturizing property, and is effective for use in toilet soap. Saponin has an antibacterial activity against yeasts and dermatophytes (causes of athlete's foot, etc.), flavone generally has an effect of expanding peripheral blood vessels to facilitate blood circulation, and resveratrol has an effect of tyrosina. -When combined with the fact that it has a whitening effect by inhibiting zease activity, toilet soap containing saponin, flavone and resveratrol is excellent in foaming properties, moisturizing properties and antibacterial properties, rough skin due to athlete's foot, etc., general rough skin It has the effect of preventing matting and keeping the skin beautiful.

The present invention is not limited to the specific embodiments described above, but can be variously modified within the scope of the present invention according to the purpose and application. Similar results were obtained when ethanol was used as the extraction solvent in place of methanol in the preparation of the yucca extract. That is,
The bulk powder of Yucca schidigera was soaked in 5 times amount of 90% ethanol to obtain a concentrated solution having an evaporation residue of 30 to 40% by weight in the same manner as described above. A brown powder was obtained in the same manner as above from the 80% ethanol extract obtained by sequentially developing and fractionating with water, 30% ethanol and 80% ethanol. The main components of this powder were saponin, flavone and resveratrol. This 3
The weight ratio of the components was 35: 4: 1 in sequence. Therefore, an ethanol extract containing such three components (preferably 40 to 90% ethanol, more preferably 70 to 9%)
(0% ethanol), the same action and effect as in the case of using the above methanol extract can be obtained. Further, as the extraction solvent, n-propanol,
iso-propanol may be used. The extraction temperature of Yucca bulk powder may be from room temperature to solvent reflux temperature. The solution obtained by filtering off and separating the insoluble matter is heated and the alcohol is distilled off to obtain a concentrated solution having a component concentration of 30 to 60% by weight. The mixing ratio of the mixed solvent for extracting the sugar component may be less than 40% alcohol. The method of drying the concentrated liquid may be vacuum drying,
Freeze drying may be used.

[0033]

EFFECTS OF THE INVENTION Since the personal cleansing agent of the present invention contains saponin, flavone and resveratrol, it is excellent in foaming property, moisturizing property and antibacterial property, and has rough skin due to athlete's foot etc., general rough skin and matting. The effect is to prevent and keep beautiful skin.

Claims (5)

[Claims] 1. A body cleanser comprising a Yucca extract. 2. The personal cleansing agent according to claim 1, wherein the yucca extract contains saponin, flavone and resveratrol. 3. The content of saponin, flavone and resveratrol when the total of the evaporation base of the detergent base and the yucca extract in the body wash is 100% by weight. 3. The personal cleansing composition according to claim 2, wherein the amount is from 0.01 to 5% by weight. 4. A method in which at least one of the roots and stems of Yucca is formed into chips and dried, or dried to form chips, and then crushed to produce a powder. Immersion and extraction in a mixed solvent of lower alcohol having 1 to 3 or lower alcohol having 1 to 3 carbon atoms and water to obtain a yucca extract, and then blending the yucca extract A method for producing a body cleanser, comprising: 5. The mixed solvent of the lower alcohol having 1 to 3 carbon atoms and water has a mixing ratio of 75% by weight or more of the lower alcohol having 1 to 3 carbon atoms. Manufacturing method of body wash of.