JPH10507177A - Ｇｆ１２０９１８ａを含む非経口医薬組成物 - Google Patents

Ｇｆ１２０９１８ａを含む非経口医薬組成物

Info

Publication number: JPH10507177A
Authority: JP; Japan
Prior art keywords: pharmaceutical composition; composition according; effective amount; safe; group
Prior art date: 1994-10-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP8512678A

Other languages

English (en)

Japanese (ja)

Inventor

トング，ウェイ−クィン

リーウェルス，ミッキー

Original Assignee

グラクソ、ウェルカム、インコーポレーテッド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-05

Filing date

1995-10-04

Publication date

1998-07-14

1995-10-04 Application filed by グラクソ、ウェルカム、インコーポレーテッド filed Critical グラクソ、ウェルカム、インコーポレーテッド

1998-07-14 Publication of JPH10507177A publication Critical patent/JPH10507177A/ja

Status Pending legal-status Critical Current

Links

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RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
229940063683 taxotere Drugs 0.000 description 1
SASWSEQJAITMKS-JJNNLWIXSA-N tert-butyl (2s)-2-[[(2s)-1-[[(2s)-1-[[(4s,5s,7s)-5-hydroxy-2,8-dimethyl-7-[[(2s,3s)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]carbamoyl]nonan-4-yl]amino]-3-(1h-imidazol-5-yl)-1-oxopropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]p Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)[C@@H](O)C[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC=1N=CC=CC=1)C(C)C)N(C)C(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H]1N(CCC1)C(=O)OC(C)(C)C)C1=CN=CN1 SASWSEQJAITMKS-JJNNLWIXSA-N 0.000 description 1
150000003512 tertiary amines Chemical class 0.000 description 1
229960003048 vinblastine Drugs 0.000 description 1
JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
229960004528 vincristine Drugs 0.000 description 1
OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
GBABOYUKABKIAF-GHYRFKGUSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-GHYRFKGUSA-N 0.000 description 1
229960002066 vinorelbine Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

JP8512678A 1994-10-05 1995-10-04 Ｇｆ１２０９１８ａを含む非経口医薬組成物 Pending JPH10507177A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US31830894A	1994-10-05	1994-10-05
US08/318,308		1994-10-05
PCT/US1995/012952 WO1996011007A1 (en)	1994-10-05	1995-10-04	Parenteral pharmaceutical compositions containing gf120918a

Publications (1)

Publication Number	Publication Date
JPH10507177A true JPH10507177A (ja)	1998-07-14

Family

ID=23237614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP8512678A Pending JPH10507177A (ja)	1994-10-05	1995-10-04	Ｇｆ１２０９１８ａを含む非経口医薬組成物

Country Status (12)

Country	Link
EP (1)	EP0784474A2 (de)
JP (1)	JPH10507177A (de)
KR (1)	KR970705997A (de)
AU (1)	AU702519B2 (de)
BR (1)	BR9509251A (de)
CA (1)	CA2201628A1 (de)
CZ (1)	CZ104197A3 (de)
HU (1)	HUT77883A (de)
NZ (1)	NZ295546A (de)
PL (1)	PL319511A1 (de)
RU (1)	RU2157687C2 (de)
WO (1)	WO1996011007A1 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2000178187A (ja) *	1998-12-15	2000-06-27	Sanochemia Pharmazeutika Ag	βカロテンの水性調合物
JP2008519828A (ja) *	2004-11-12	2008-06-12	チョンクンダンファーマセウティカルコーポレイション	タクロリムスの注射
JP2013500321A (ja) *	2009-07-30	2013-01-07	サノフイ	医薬製剤
JP2014088444A (ja) *	2000-06-30	2014-05-15	Talon Therapeutics Inc	リポソーム抗新生物薬剤およびその使用

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2333293B (en) *	1996-10-18	2000-07-12	Xenova Ltd	Process for the preparation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide used as anti cancer compounds
GB9708805D0 (en)	1997-05-01	1997-06-25	Smithkline Beecham Plc	Compounds
GB9710612D0 (en) *	1997-05-23	1997-07-16	Glaxo Group Ltd	Synthesis of acridine derivatives
GB9810876D0 (en)	1998-05-20	1998-07-22	Smithkline Beecham Plc	Compounds
US5922754A (en) *	1998-10-02	1999-07-13	Abbott Laboratories	Pharmaceutical compositions containing paclitaxel
CA2346689A1 (en)	1998-10-08	2000-04-20	Gregor James Macdonald	Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
EP1749540B1 (de)	1999-05-17	2010-10-13	Cancer Research Ventures Limited	Zubereitungen zur Erhöhung der Bioverfügbarkeit von oral verabreichten pharmazeutischen Verbindungen
US6521635B1 (en)	2000-01-20	2003-02-18	The United States Of America As Represented By The Department Of Health And Human Services	Inhibition of MXR transport by acridine derivatives
WO2003002150A1 (en) *	2001-06-28	2003-01-09	Wyeth	Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma
RU2205634C1 (ru) *	2002-06-18	2003-06-10	Нестерук Владимир Викторович	Лекарственное средство, обладающее противорвотным действием

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4544657A (en) *	1983-05-19	1985-10-01	Hoffmann-La Roche Inc.	Substituted isoquinolines
SK280864B6 (en) *	1991-01-11	2000-08-14	Laboratoires Glaxo Sa	Acridine derivatives, process for their preparation, and pharmaceutical compositions based thereon

1995
- 1995-10-04 EP EP95938184A patent/EP0784474A2/de not_active Ceased
- 1995-10-04 NZ NZ295546A patent/NZ295546A/xx unknown
- 1995-10-04 CZ CZ971041A patent/CZ104197A3/cs unknown
- 1995-10-04 HU HU9702291A patent/HUT77883A/hu unknown
- 1995-10-04 KR KR1019970702223A patent/KR970705997A/ko not_active Withdrawn
- 1995-10-04 AU AU38913/95A patent/AU702519B2/en not_active Ceased
- 1995-10-04 WO PCT/US1995/012952 patent/WO1996011007A1/en not_active Ceased
- 1995-10-04 RU RU97107466/14A patent/RU2157687C2/ru active
- 1995-10-04 JP JP8512678A patent/JPH10507177A/ja active Pending
- 1995-10-04 PL PL95319511A patent/PL319511A1/xx unknown
- 1995-10-04 CA CA002201628A patent/CA2201628A1/en not_active Abandoned
- 1995-10-04 BR BR9509251A patent/BR9509251A/pt not_active Application Discontinuation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2000178187A (ja) *	1998-12-15	2000-06-27	Sanochemia Pharmazeutika Ag	βカロテンの水性調合物
JP2014088444A (ja) *	2000-06-30	2014-05-15	Talon Therapeutics Inc	リポソーム抗新生物薬剤およびその使用
JP2008519828A (ja) *	2004-11-12	2008-06-12	チョンクンダンファーマセウティカルコーポレイション	タクロリムスの注射
JP2013500321A (ja) *	2009-07-30	2013-01-07	サノフイ	医薬製剤

Also Published As

Publication number	Publication date
RU2157687C2 (ru)	2000-10-20
WO1996011007A1 (en)	1996-04-18
AU3891395A (en)	1996-05-02
NZ295546A (en)	1999-01-28
KR970705997A (ko)	1997-11-03
PL319511A1 (en)	1997-08-18
EP0784474A2 (de)	1997-07-23
BR9509251A (pt)	1997-10-21
MX9702473A (es)	1997-07-31
CZ104197A3 (en)	1997-09-17
AU702519B2 (en)	1999-02-25
HUT77883A (hu)	1998-09-28
CA2201628A1 (en)	1996-04-18

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AU702519B2 (en)	1999-02-25	Parenteral pharmaceutical compositions containing GF120918A
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US20110130446A1 (en)	2011-06-02	Injectable taxane pharmaceutical composition
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TW201215412A (en)	2012-04-16	Stable pharmaceutical composition
MXPA97002473A (en)	1997-12-01	Parenteral pharmaceutical compositions containing gf1209
WO2025094002A1 (en)	2025-05-08	Lurbinectedin formulation
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US20060094692A1 (en)	2006-05-04	Pharmaceutical formulations of camptothecins and process for making same
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WO2026078715A1 (en)	2026-04-16	Injectable composition of aprepitant
CN1164189A (zh)	1997-11-05	含有gf120918a的非肠道药物组合物
WO2011000811A2 (en)	2011-01-06	Organic compounds
WO2018109731A1 (en)	2018-06-21	Pharmaceutical compositions of taxane and its derivatives

JPH10507177A - Ｇｆ１２０９１８ａを含む非経口医薬組成物 - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (3)

Publications (1)

Family

ID=23237614

Family Applications (1)

Country Status (12)

Cited By (4)

Families Citing this family (10)

Family Cites Families (2)

Cited By (4)

Also Published As

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