JPH10509740A5 - - Google Patents
Info
- Publication number
- JPH10509740A5 JPH10509740A5 JP1997508693A JP50869397A JPH10509740A5 JP H10509740 A5 JPH10509740 A5 JP H10509740A5 JP 1997508693 A JP1997508693 A JP 1997508693A JP 50869397 A JP50869397 A JP 50869397A JP H10509740 A5 JPH10509740 A5 JP H10509740A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US190195P | 1995-08-04 | 1995-08-04 | |
| US08/693,831 US6017700A (en) | 1995-08-04 | 1996-07-31 | Cationic oligonucleotides, and related methods of synthesis and use |
| US08/693,831 | 1996-07-31 | ||
| US60/001,901 | 1996-07-31 | ||
| PCT/US1996/013056 WO1997006183A1 (en) | 1995-08-04 | 1996-08-01 | Cationic oligonucleotides, and related methods of synthesis and use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007208670A Division JP2008013571A (ja) | 1995-08-04 | 2007-08-09 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH10509740A JPH10509740A (ja) | 1998-09-22 |
| JPH10509740A5 true JPH10509740A5 (2) | 2004-09-09 |
Family
ID=26669648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9508693A Expired - Lifetime JPH10509740A (ja) | 1995-08-04 | 1996-08-01 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
| JP2007208670A Pending JP2008013571A (ja) | 1995-08-04 | 2007-08-09 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007208670A Pending JP2008013571A (ja) | 1995-08-04 | 2007-08-09 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6017700A (2) |
| EP (1) | EP0785942A1 (2) |
| JP (2) | JPH10509740A (2) |
| AU (1) | AU702309B2 (2) |
| CA (1) | CA2201963A1 (2) |
| WO (1) | WO1997006183A1 (2) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3090102A (en) * | 2000-12-14 | 2002-06-24 | Gen Probe Inc | Method and kit for enhancing the association rates of polynucleotides |
| CA2494571C (en) * | 2003-12-02 | 2010-02-09 | F.Hoffmann-La Roche Ag | Oligonucleotides containing molecular rods |
| CA2659103C (en) * | 2006-07-12 | 2019-05-21 | The Regents Of The University Of California | Transducible delivery of nucleic acids by reversible phosphotriester charge neutralization protecting groups |
| RU2572826C2 (ru) | 2008-12-02 | 2016-01-20 | Чиралджен, Лтд. | Способ синтеза модифицированных по атому фосфора нуклеиновых кислот |
| CA2767253A1 (en) | 2009-07-06 | 2011-01-13 | Ontorii, Inc. | Novel nucleic acid prodrugs and methods of use thereof |
| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| KR102097053B1 (ko) * | 2011-05-10 | 2020-04-03 | 가부시키가이샤 보낙 | 동위체를 갖는 인산 화합물의 제조 방법 |
| AU2012284265B2 (en) | 2011-07-19 | 2017-08-17 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| JP6453212B2 (ja) * | 2012-07-13 | 2019-01-16 | ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． | キラル制御 |
| CN104684923B (zh) | 2012-07-13 | 2018-09-28 | 株式会社新日本科学 | 手性核酸佐剂 |
| SG11201500239VA (en) | 2012-07-13 | 2015-03-30 | Wave Life Sciences Japan | Asymmetric auxiliary group |
| US9950001B2 (en) | 2012-08-20 | 2018-04-24 | The Regents Of The University Of California | Polynucleotides having bioreversible groups |
| EP3013964B1 (en) | 2013-06-28 | 2020-05-06 | ethris GmbH | Compositions for introducing rna into cells |
| US9410172B2 (en) | 2013-09-16 | 2016-08-09 | General Electric Company | Isothermal amplification using oligocation-conjugated primer sequences |
| JPWO2015108046A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
| WO2015108048A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| WO2015108047A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| ES2917473T3 (es) | 2014-01-16 | 2022-07-08 | Wave Life Sciences Ltd | Diseño quiral |
| WO2015128030A1 (en) | 2014-02-26 | 2015-09-03 | Ethris Gmbh | Compositions for gastrointestinal administration of rna |
| EP3034539A1 (en) | 2014-12-19 | 2016-06-22 | Ethris GmbH | Compositions for introducing nucleic acid into cells |
| JP2019532027A (ja) | 2016-08-17 | 2019-11-07 | ソルスティス バイオロジクス，リミティッド | ポリヌクレオチド構築物 |
| MX2019012295A (es) | 2017-04-14 | 2020-02-07 | Tollnine Inc | Polinucleotidos inmunomoduladores, conjugados de anticuerpos de los mismos y metodos para su uso. |
| WO2019006455A1 (en) | 2017-06-30 | 2019-01-03 | Solstice Biologics, Ltd. | AUXILIARIES OF CHIRAL PHOSPHORAMIDITIS AND METHODS OF USE THEREOF |
| MX2020011166A (es) | 2018-04-25 | 2022-10-19 | Ethris Gmbh | Agentes crioprotectores para formulaciones en forma de particulas. |
| AU2022226409A1 (en) | 2021-02-26 | 2023-08-10 | Ethris Gmbh | Formulations for aerosol formation and aerosols for the delivery of nucleic acid |
| EP4331617A4 (en) * | 2021-04-28 | 2025-11-12 | Japan Science & Tech Agency | ARTIFICIAL NUCLEIC ACID AND METHOD OF ADMINISTRATING NUCLEIC ACID USING IT |
| EP4577243A1 (en) | 2022-08-26 | 2025-07-02 | Ethris GmbH | Stable lipid or lipidoid nanoparticle suspensions |
| EP4327829A1 (en) | 2022-08-26 | 2024-02-28 | Ethris GmbH | Stabilization of lipid or lipidoid nanoparticle suspensions |
| WO2025045767A1 (en) | 2023-08-25 | 2025-03-06 | Ethris Gmbh | Stabilized lipid and lipidoid nanoparticle formulations with specific surfactant properties for enhanced pharmaceutical applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586704B1 (fr) * | 1985-09-04 | 1987-12-18 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation et a un groupe chimique activable, leur synthese et leurs applications a titre de nucleases artificielles specifiques de sequences. centre national de la recherche scientifique (cnrs) |
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| DE3916871A1 (de) * | 1989-05-24 | 1990-11-29 | Boehringer Mannheim Gmbh | Modifiziertes phosphoramidit-verfahren zur herstellung von modifizierten nukleinsaeuren |
| US4958013A (en) * | 1989-06-06 | 1990-09-18 | Northwestern University | Cholesteryl modified oligonucleotides |
| CA2122470A1 (en) * | 1991-11-25 | 1993-06-10 | Alan F. Cook | Oligonucleotides having aminohydrocarbon phosphonate moieties |
-
1996
- 1996-07-31 US US08/693,831 patent/US6017700A/en not_active Expired - Lifetime
- 1996-08-01 JP JP9508693A patent/JPH10509740A/ja not_active Expired - Lifetime
- 1996-08-01 WO PCT/US1996/013056 patent/WO1997006183A1/en not_active Ceased
- 1996-08-01 AU AU68971/96A patent/AU702309B2/en not_active Ceased
- 1996-08-01 EP EP96929675A patent/EP0785942A1/en not_active Withdrawn
- 1996-08-01 CA CA002201963A patent/CA2201963A1/en not_active Abandoned
-
2007
- 2007-08-09 JP JP2007208670A patent/JP2008013571A/ja active Pending